Expression of CEACAM5 in colorectal cancer

RECTUM ADENOCARCINOMA (READ) - Interactive survival scatter plotⁱ

The Survival Scatter plot shows the clinical status (i.e. dead or alive) for all individuals in the patient cohort, based on the same data that underlies the corresponding Kaplan-Meier plots. Patients that are alive at last time for follow-up are shown in blue and patients who have died during the study are shown in red.

The x-axis shows the expression levels (FPKM) of the investigated gene in the tumor tissue at the time of diagnosis. The y-axis shows the follow-up time after diagnosis (years). Both axes are complimented with kernel density curves demonstrating the data density over the axes. The top density plot shows the expression levels (FPKM) distribution among dead (red) and alive patients (blue). The right density plot shows the data density of the survived years of dead patients with high and low expression levels respectively, stratified using the cutoff indicated by the vertical dashed line through the Survival Scatter plot. This cutoff is automatically defined based on the FPKM cutoff that minimizes the p-score. The cutoff can be changed by dragging the vertical line or by entering a cutoff value in the square labeled "Current cut-off".

Under the Survival Scatter plot the p-score landscape (black curve; left axis) is shown together with dead median separation (red curve; right axis). Dead median separation is the difference in median mRNA expression between patients who have died with high and low expression, respectively. It is calculated as follows: median FPKM expression of dead patients with high expression - median FPKM expression of dead patients with low expression. This is intended to aid the user in visually exploring custom cutoffs and the associated p-scores and dead median separation.

Individual patient data is displayed and can be filtered by clicking on one or more of the category buttons on the top of the page. Categories describing expression level and patient information include: high, low, alive, dead, female, male and tumor stages. The scale of the x-axis can be toggled between linear and log-scale by clicking on the "x log" button. Mouse-over function shows TCGA ID, patient information and mRNA expression (FPKM) for each patient.

& Survival analysisⁱ

Stage:

Survival analysis

Current cut offⁱ:
Best expression cut offⁱ: 1341.52
Median expressionⁱ: N/A
Median follow up timeⁱ: N/A
P scoreⁱ N/A
5-year survival highⁱ N/A
5-year survival lowⁱ N/A

TCGA RNA samplesⁱ

Average FPKM

1110.7

Number of samples

159

Samples

Sample	Description	FPKM
TCGA-AF-5654-01A	73 years, female, white, stage:i, dead, 512 days	3216.2
TCGA-CI-6624-01C	53 years, female, white, stage:i, alive, 1466 days	3086.6
TCGA-DC-6160-01A	68 years, male, white, stage:i, alive, 1339 days	2520.4
TCGA-EF-5831-01A	72 years, male, white, stage:iia, alive, 127 days	2432.9
TCGA-AG-3909-01A	69 years, female, stage:iiib, alive, 608 days	2362.8
TCGA-EI-6508-01A	48 years, female, white, stage:iiib, alive, 636 days	2232.7
TCGA-DC-6683-01A	43 years, male, white, stage:iiib, alive, 762 days	2161.6
TCGA-EI-6514-01A	59 years, female, white, stage:iia, alive, 496 days	2117.7
TCGA-AG-4021-01A	84 years, female, stage:iv, dead, 121 days	2117.6
TCGA-F5-6465-01A	64 years, female, white, stage:iia, alive, 1506 days	2111.1
TCGA-EI-6881-01A	60 years, male, white, stage:iiia, alive, 499 days	2093.2
TCGA-EI-7002-01A	58 years, male, white, stage:iv, alive, 364 days	2076.8
TCGA-AG-3592-01A	68 years, male, stage:iia, alive, 1035 days	2012.9
TCGA-AH-6897-01A	48 years, male, white, stage:i, alive, 804 days	1973.6
TCGA-AG-3725-01A	90 years, female, stage:iii, alive, 638 days	1906.1
TCGA-F5-6812-01A	67 years, male, white, stage:iia, alive, 1110 days	1879.2
TCGA-EI-6506-01A	78 years, female, white, stage:iia, alive, 625 days	1869.3
TCGA-AH-6547-01A	79 years, female, white, dead, 76 days	1809.8
TCGA-EI-6510-01A	77 years, female, white, alive, 556 days	1805.4
TCGA-AF-2693-01A	75 years, male, white, stage:i, alive, 1155 days	1785.2
TCGA-CL-4957-01A	79 years, female, dead, 425 days	1746.0
TCGA-CI-6622-01A	74 years, male, white, stage:iib, alive, 1362 days	1740.9
TCGA-EI-6884-01A	71 years, male, white, stage:iiia, alive, 328 days	1727.1
TCGA-AG-A032-01A	68 years, male, stage:iiib, alive, 1157 days	1704.7
TCGA-AG-3896-01A	85 years, female, stage:i, alive, 31 days	1701.0
TCGA-DC-5337-01A	69 years, male, white, stage:i, alive, 792 days	1695.8
TCGA-DC-6681-01A	70 years, female, white, stage:iva, alive, 790 days	1669.0
TCGA-F5-6811-01A	72 years, female, white, stage:iia, alive, 979 days	1620.1
TCGA-F5-6571-01A	62 years, female, white, stage:iia, alive, 1288 days	1616.5
TCGA-AG-A02X-01A	77 years, male, stage:i, alive, 1247 days	1608.1
TCGA-AG-3582-01A	75 years, male, stage:iv, dead, 1096 days	1598.2
TCGA-AH-6549-01A	66 years, male, white, alive, 532 days	1575.9
TCGA-CI-6623-01B	44 years, male, white, stage:i, alive, 1443 days	1561.4
TCGA-AG-3893-01A	74 years, male, stage:iiib, alive, 1065 days	1535.2
TCGA-AG-A00C-01A	49 years, female, stage:iiib, alive, 183 days	1507.0
TCGA-G5-6235-01A	72 years, male, white, stage:iiib, alive, 1696 days	1477.4
TCGA-AH-6544-01A	60 years, male, white, alive, 1173 days	1454.9
TCGA-F5-6813-01A	70 years, male, white, stage:iiic, dead, 598 days	1446.9
TCGA-CI-6621-01A	63 years, male, white, stage:iiib, alive, 419 days	1440.3
TCGA-AG-A025-01A	62 years, female, stage:i, alive, 1520 days	1431.3
TCGA-DC-6157-01A	48 years, male, black or african american, stage:i, alive, 1581 days	1414.9
TCGA-EI-6882-01A	59 years, male, white, stage:iia, alive, 262 days	1414.5
TCGA-DC-6682-01A	57 years, male, white, stage:iia, alive, 762 days	1388.0
TCGA-AG-3732-01A	78 years, female, stage:i, alive, 1003 days	1364.5
TCGA-AF-A56N-01A	47 years, female, black or african american, stage:iia, alive, 360 days	1349.0
TCGA-AF-6136-01A	72 years, female, white, stage:iiib, alive, 741 days	1344.3
TCGA-AG-3583-01A	66 years, male, stage:iv, dead, 610 days	1338.7
TCGA-AG-A016-01A	55 years, male, stage:iv, alive, 276 days	1328.4
TCGA-DC-6156-01A	62 years, male, white, stage:iva, alive, 943 days	1277.3
TCGA-AG-A015-01A	64 years, female, stage:i, alive, 1096 days	1274.0
TCGA-AG-3742-01A	85 years, female, stage:i, alive, 30 days	1273.4
TCGA-AG-A01J-01A	59 years, female, stage:iia, alive, 31 days	1272.4
TCGA-AG-3890-01A	62 years, male, stage:i, alive, 518 days	1271.0
TCGA-AF-3911-01A	48 years, male, white, stage:iiic, alive, 1148 days	1266.4
TCGA-AG-3594-01A	77 years, male, stage:iia, dead, 61 days	1263.2
TCGA-AG-A020-01A	57 years, female, stage:iii, alive, 31 days	1262.1
TCGA-EI-6885-01A	57 years, female, white, stage:iv, alive, 415 days	1255.6
TCGA-AF-6655-01A	66 years, male, white, stage:iiia, alive, 609 days	1251.0
TCGA-AF-3913-01A	60 years, male, black or african american, stage:iv, dead, 316 days	1233.0
TCGA-DC-5869-01A	62 years, female, black or african american, stage:iiib, alive, 943 days	1221.8
TCGA-AG-3587-01A	65 years, male, stage:i, alive, 1400 days	1214.9
TCGA-CI-6620-01A	41 years, female, white, stage:iva, alive, 1009 days	1204.7
TCGA-AF-2691-01A	48 years, female, white, stage:i, alive, 1309 days	1198.8
TCGA-F5-6864-01A	74 years, female, white, stage:iiib, alive, 379 days	1196.5
TCGA-CL-5918-01A	90 years, female, white, stage:iia, alive, 218 days	1191.1
TCGA-G5-6641-01A	67 years, male, white, stage:iiia, alive, 804 days	1190.9
TCGA-AG-A026-01A	66 years, male, stage:ii, dead, 59 days	1178.8
TCGA-AG-3580-01A	67 years, male, stage:i, alive, 244 days	1168.7
TCGA-DY-A1DC-01A	72 years, female, white, stage:iia, dead, 1258 days	1166.6
TCGA-DC-6154-01A	57 years, female, white, stage:iva, alive, 365 days	1165.1
TCGA-DY-A1DG-01A	75 years, male, white, stage:iva, dead, 1566 days	1164.4
TCGA-DY-A0XA-01A	57 years, female, white, stage:iia, alive, 3846 days	1163.1
TCGA-EI-6512-01A	64 years, female, white, stage:iiib, alive, 538 days	1154.6
TCGA-AF-A56K-01A	56 years, male, black or african american, stage:iia, alive, 2635 days	1153.4
TCGA-AG-4008-01A	63 years, male, stage:iia, alive, 518 days	1133.9
TCGA-AG-3581-01A	63 years, male, stage:i, alive, 215 days	1122.3
TCGA-AG-3584-01A	60 years, male, stage:iv, dead, 730 days	1077.8
TCGA-F5-6861-01A	60 years, female, white, stage:iia, alive, 1160 days	1074.8
TCGA-AH-6643-01A	50 years, male, white, stage:iiic, dead, 1314 days	1071.0
TCGA-DC-4749-01A	57 years, male, white, stage:i, alive, 762 days	1064.9
TCGA-AH-6903-01A	46 years, male, white, stage:iiib, alive, 592 days	1028.5
TCGA-AG-4007-01A	87 years, male, stage:iv, alive, 31 days	1027.1
TCGA-F5-6863-01A	71 years, female, white, stage:iiib, dead, 361 days	1026.3
TCGA-AG-3609-01A	65 years, female, stage:iiic, alive, 608 days	1007.5
TCGA-CI-6619-01B	41 years, male, white, stage:iv, alive, 184 days	1006.9
TCGA-EF-5830-01A	54 years, male, white, stage:iib, alive, 106 days	992.0
TCGA-AF-A56L-01A	48 years, female, black or african american, stage:iiic, alive, 2007 days	980.8
TCGA-AG-4001-01A	74 years, female, stage:iia, alive, 1096 days	972.8
TCGA-AG-A00H-01A	75 years, male, stage:iia, alive, 790 days	966.5
TCGA-AG-3578-01A	76 years, female, stage:iia, alive, 974 days	958.0
TCGA-EI-6513-01A	59 years, male, white, stage:iiib, alive, 497 days	936.9
TCGA-EI-6507-01A	60 years, male, white, stage:iia, alive, 607 days	921.7
TCGA-CL-5917-01A	71 years, female, white, stage:iiic, alive, 2376 days	913.6
TCGA-AG-3882-01A	66 years, female, stage:i, alive, 608 days	913.3
TCGA-AG-3612-01A	55 years, female, stage:iiib, alive, 608 days	896.4
TCGA-AH-6644-01A	73 years, male, white, alive, 838 days	895.7
TCGA-AG-4022-01A	59 years, female, stage:ii, alive, 1400 days	887.6
TCGA-AF-2692-01A	54 years, female, white, stage:iia, alive, 412 days	850.9
TCGA-AG-3898-01A	61 years, male, stage:iia, alive, 1461 days	848.0
TCGA-AG-A01N-01A	68 years, female, stage:iv, alive, 943 days	841.6
TCGA-F5-6464-01A	77 years, female, white, stage:iiic, dead, 303 days	841.0
TCGA-F5-6702-01A	71 years, male, white, stage:iva, alive, 869 days	835.7
TCGA-AG-3593-01A	72 years, female, stage:iia, alive, 1035 days	832.8
TCGA-AG-3878-01A	64 years, male, stage:i, alive, 30 days	825.5
TCGA-AG-A00Y-01A	68 years, male, stage:iia, alive, 700 days	819.3
TCGA-AG-4005-01A	64 years, male, stage:iv, alive, 427 days	817.7
TCGA-DC-6158-01A	70 years, male, white, stage:i, dead, 334 days	811.5
TCGA-G5-6233-01A	74 years, male, white, dead, 556 days	800.8
TCGA-AG-A023-01A	62 years, female, stage:iv, dead, 1581 days	797.6
TCGA-AG-A036-01A	71 years, male, stage:iii, alive, 3562 days	796.6
TCGA-AG-3574-01A	89 years, female, stage:ii, dead, 1096 days	791.7
TCGA-AG-3728-01A	73 years, male, stage:iiib, alive, 912 days	791.3
TCGA-EI-6511-01A	52 years, male, white, stage:iiib, alive, 482 days	779.7
TCGA-AG-3586-01A	72 years, female, stage:iii, alive, 31 days	763.4
TCGA-DY-A1DE-01A	56 years, female, white, stage:iia, alive, 3932 days	748.6
TCGA-DT-5265-01A	51 years, male, asian, stage:ii, alive, 384 days	730.1
TCGA-AG-3599-01A	70 years, male, stage:i, alive, 366 days	726.2
TCGA-AG-3611-01A	72 years, male, stage:iia, alive, 424 days	722.2
TCGA-BM-6198-01A	73 years, male, white, stage:iiib, alive, 646 days	716.9
TCGA-DC-4745-01A	49 years, female, white, stage:iiib, alive, 639 days	711.4
TCGA-AG-3591-01A	66 years, female, stage:iia, alive, 1035 days	703.3
TCGA-AG-3901-01A	67 years, female, stage:iiib, alive, 761 days	698.8
TCGA-AG-3999-01A	61 years, female, stage:iiic, alive, 853 days	689.0
TCGA-AG-3726-01A	63 years, female, stage:i, alive, 243 days	680.3
TCGA-AG-3902-01A	61 years, male, stage:iia, alive, 974 days	679.2
TCGA-AG-A02N-01A	67 years, male, stage:ii, alive, 1885 days	677.9
TCGA-EI-7004-01A	37 years, female, white, alive, 257 days	676.8
TCGA-AF-6672-01A	43 years, male, white, stage:iv, alive, 748 days	661.4
TCGA-AG-3608-01A	79 years, female, stage:iia, alive, 485 days	619.7
TCGA-AF-2690-01A	77 years, female, white, stage:iiic, dead, 524 days	604.5
TCGA-AG-3598-01A	69 years, male, stage:iia, alive, 1522 days	598.9
TCGA-AG-3600-01A	62 years, male, stage:iiic, alive, 184 days	597.0
TCGA-AF-3400-01A	54 years, male, white, stage:iia, alive, 1049 days	591.2
TCGA-AF-4110-01A	77 years, male, white, stage:iva, alive, 912 days	568.4
TCGA-AG-3894-01A	65 years, male, stage:iia, alive, 426 days	568.0
TCGA-G5-6572-01A	56 years, male, white, dead, 1432 days	567.5
TCGA-AG-A014-01A	86 years, male, stage:i, alive, 485 days	563.9
TCGA-AG-A008-01A	50 years, female, stage:i, alive, 424 days	560.9
TCGA-AG-3727-01A	78 years, female, stage:iii, alive, 30 days	545.4
TCGA-EI-6883-01A	63 years, male, white, stage:iic, alive, 350 days	507.8
TCGA-AG-3731-01A	65 years, male, stage:iv, alive, 1126 days	498.1
TCGA-AG-A011-01A	80 years, male, stage:iia, alive, 1126 days	476.5
TCGA-AF-2687-01A	57 years, male, white, stage:iiic, alive, 1427 days	437.0
TCGA-AG-3892-01A	57 years, female, stage:i, alive, 396 days	424.0
TCGA-AG-3887-01A	68 years, male, stage:iia, alive, 1124 days	411.3
TCGA-AG-3605-01A	85 years, female, stage:iv, alive, 30 days	400.5
TCGA-AG-3885-01A	71 years, female, stage:iiib, alive, 546 days	397.1
TCGA-AG-3881-01A	83 years, female, stage:iia, alive, 579 days	384.9
TCGA-AG-3883-01A	69 years, male, stage:i, alive, 31 days	298.4
TCGA-EI-6509-01A	53 years, male, white, stage:iiic, alive, 517 days	262.3
TCGA-EI-6917-01A	33 years, male, white, stage:iiia, alive, 531 days	254.6
TCGA-AG-A02G-01A	66 years, male, stage:iv, dead, 1185 days	177.3
TCGA-DY-A1H8-01A	77 years, female, white, stage:iiia, dead, 992 days	170.2
TCGA-DC-6155-01A	31 years, female, white, stage:iiia, alive, 425 days	162.4
TCGA-F5-6814-01A	57 years, male, white, stage:iia, alive, 1131 days	154.6
TCGA-AG-A002-01A	35 years, male, stage:i, alive, 638 days	106.2
TCGA-DY-A1DD-01A	77 years, female, white, stage:iiib, dead, 1741 days	73.3
TCGA-DY-A1DF-01A	73 years, female, white, stage:iiic, dead, 734 days	52.4
TCGA-AG-3575-01A	51 years, male, stage:ii, alive, 365 days	32.3
Show allShow less