The intermediate filament protein nestin (gene: NES) is highlighted in kidney through multiplex immunohistochemistry (mIHC/IF).

The glomeruli are the main filtration units of the kidney and are composed of tufts of capillaries formed from endothelial cells and podocytes. Utilizing the mIHC/IF kidney panel, nestin (NES) - a cytoskeleton-associated intermediate filament protein - is localized (green) to the cytoplasm of glomerular endothelial cells (magenta) and podocytes (yellow). Other visualized kidney structures include proximal tubular cells (white).

For more details about the mIHC/IF technique visit our method page.