Expression of ACTB in pancreatic cancer

PANCREATIC CANCER - Interactive survival scatter plotⁱ

The Survival Scatter plot shows the clinical status (i.e. dead or alive) for all individuals in the patient cohort, based on the same data that underlies the corresponding Kaplan-Meier plots. Patients that are alive at last time for follow-up are shown in blue and patients who have died during the study are shown in red.

The x-axis shows the expression levels (FPKM) of the investigated gene in the tumor tissue at the time of diagnosis. The y-axis shows the follow-up time after diagnosis (years). Both axes are complimented with kernel density curves demonstrating the data density over the axes. The top density plot shows the expression levels (FPKM) distribution among dead (red) and alive patients (blue). The right density plot shows the data density of the survived years of dead patients with high and low expression levels respectively, stratified using the cutoff indicated by the vertical dashed line through the Survival Scatter plot. This cutoff is automatically defined based on the FPKM cutoff that minimizes the p-score. The cutoff can be changed by dragging the vertical line or by entering a cutoff value in the square labeled "Current cut-off".

Under the Survival Scatter plot the p-score landscape (black curve; left axis) is shown together with dead median separation (red curve; right axis). Dead median separation is the difference in median mRNA expression between patients who have died with high and low expression, respectively. It is calculated as follows: median FPKM expression of dead patients with high expression - median FPKM expression of dead patients with low expression. This is intended to aid the user in visually exploring custom cutoffs and the associated p-scores and dead median separation.

Individual patient data is displayed and can be filtered by clicking on one or more of the category buttons on the top of the page. Categories describing expression level and patient information include: high, low, alive, dead, female, male and tumor stages. The scale of the x-axis can be toggled between linear and log-scale by clicking on the "x log" button. Mouse-over function shows TCGA ID, patient information and mRNA expression (FPKM) for each patient.

& Survival analysisⁱ

ACTB is not prognostic in pancreatic cancer

Stage:

Survival analysis

Current cut offⁱ:
Best expression cut offⁱ: 1379.74
Median expressionⁱ: N/A
Median follow up timeⁱ: N/A
P scoreⁱ N/A
5-year survival highⁱ N/A
5-year survival lowⁱ N/A

TCGA RNA samplesⁱ

Average FPKM

1744.6

Number of samples

176

Samples

Sample	Description	FPKM
TCGA-2J-AABP-01A	58 years, female, white, stage:iib, alive, 463 days	3102.1
TCGA-IB-7885-01A	78 years, female, white, stage:iib, alive, 1257 days	3101.1
TCGA-2J-AAB6-01A	75 years, male, white, stage:iia, dead, 293 days	3043.3
TCGA-HV-A7OL-01A	70 years, male, asian, stage:iia, alive, 252 days	2936.5
TCGA-HV-A5A6-01A	65 years, female, asian, stage:iib, dead, 2036 days	2883.8
TCGA-2J-AABT-01A	72 years, female, white, stage:iib, alive, 319 days	2871.0
TCGA-3A-A9IC-01A	61 years, female, white, stage:iib, dead, 738 days	2756.2
TCGA-M8-A5N4-01A	48 years, female, stage:iia, alive, 584 days	2723.9
TCGA-YH-A8SY-01A	73 years, female, white, alive, 388 days	2714.4
TCGA-F2-A44G-01A	79 years, female, white, stage:iib, dead, 233 days	2645.4
TCGA-FB-AAQ2-01A	81 years, female, white, stage:iib, dead, 153 days	2644.4
TCGA-Z5-AAPL-01A	74 years, female, white, stage:iia, alive, 467 days	2632.5
TCGA-RB-A7B8-01A	81 years, female, white, stage:iib, dead, 466 days	2583.1
TCGA-XD-AAUL-01A	56 years, male, white, stage:iia, alive, 498 days	2576.5
TCGA-2J-AAB8-01A	71 years, male, white, stage:iib, alive, 80 days	2566.2
TCGA-PZ-A5RE-01A	44 years, female, white, stage:iib, dead, 470 days	2514.7
TCGA-Q3-A5QY-01A	58 years, male, white, stage:iib, alive, 416 days	2500.5
TCGA-YB-A89D-01A	59 years, male, white, stage:iib, alive, 350 days	2470.4
TCGA-2J-AAB1-01A	65 years, male, white, stage:iib, dead, 66 days	2467.8
TCGA-FB-A7DR-01A	48 years, male, asian, stage:iia, dead, 353 days	2400.0
TCGA-3A-A9J0-01A	75 years, male, white, stage:iib, alive, 743 days	2392.8
TCGA-HZ-A77P-01A	77 years, male, white, stage:iib, alive, 330 days	2390.2
TCGA-S4-A8RO-01A	75 years, female, white, stage:iib, alive, 525 days	2366.5
TCGA-FB-AAQ0-01A	68 years, male, white, stage:iia, dead, 473 days	2348.5
TCGA-3A-A9IH-01A	66 years, female, white, stage:ia, alive, 1021 days	2275.4
TCGA-IB-AAUS-01A	84 years, female, white, stage:iib, alive, 225 days	2271.3
TCGA-IB-AAUQ-01A	50 years, male, white, stage:iib, dead, 183 days	2234.8
TCGA-HZ-A77O-01A	77 years, female, white, stage:iib, dead, 160 days	2231.3
TCGA-2L-AAQL-01A	82 years, male, white, stage:iib, dead, 292 days	2229.7
TCGA-2J-AABO-01A	43 years, male, white, stage:iib, alive, 440 days	2229.6
TCGA-IB-AAUU-01A	35 years, male, white, stage:iib, alive, 245 days	2227.7
TCGA-FB-AAQ3-01A	65 years, female, white, stage:iib, dead, 31 days	2222.7
TCGA-Q3-AA2A-01A	64 years, female, white, stage:ib, alive, 95 days	2201.2
TCGA-IB-A5SS-01A	64 years, female, white, stage:iib, dead, 460 days	2196.1
TCGA-IB-7893-01A	64 years, male, white, stage:iia, dead, 117 days	2189.3
TCGA-IB-7646-01A	60 years, male, white, stage:iib, dead, 145 days	2166.4
TCGA-IB-A5SQ-01A	56 years, female, white, stage:ib, dead, 219 days	2164.5
TCGA-IB-AAUR-01A	67 years, male, white, stage:iib, alive, 338 days	2152.8
TCGA-2L-AAQA-01A	76 years, male, white, stage:iib, dead, 143 days	2151.7
TCGA-3A-A9IB-01A	69 years, female, white, stage:iib, dead, 224 days	2143.7
TCGA-YY-A8LH-01A	61 years, female, white, stage:iib, alive, 2016 days	2142.1
TCGA-OE-A75W-01A	75 years, male, white, stage:iia, dead, 267 days	2134.9
TCGA-XD-AAUI-01A	50 years, female, white, stage:iib, dead, 366 days	2134.7
TCGA-2J-AABU-01A	56 years, male, white, stage:iib, dead, 277 days	2133.9
TCGA-US-A779-01A	54 years, female, white, stage:iib, dead, 511 days	2118.2
TCGA-3A-A9I7-01A	45 years, male, black or african american, stage:iib, alive, 1323 days	2117.5
TCGA-FB-AAPZ-01A	54 years, male, white, stage:iib, alive, 716 days	2115.7
TCGA-2J-AABH-01A	61 years, male, white, stage:iia, alive, 1287 days	2105.6
TCGA-2J-AAB4-01A	48 years, male, white, stage:iib, alive, 729 days	2102.9
TCGA-HZ-A9TJ-01A	70 years, male, white, stage:iv, alive, 603 days	2098.8
TCGA-2J-AABK-01A	71 years, male, white, stage:iib, alive, 484 days	2080.9
TCGA-FB-AAPS-01A	62 years, female, white, stage:iib, alive, 228 days	2062.8
TCGA-2J-AABF-01A	73 years, male, white, stage:iib, dead, 691 days	2062.7
TCGA-IB-7889-01A	86 years, female, white, stage:iib, dead, 481 days	2055.8
TCGA-US-A77J-01A	81 years, female, white, stage:iib, dead, 568 days	2023.8
TCGA-HZ-A4BH-01A	75 years, male, white, stage:iib, alive, 194 days	2017.1
TCGA-IB-AAUN-01A	74 years, female, white, stage:ib, dead, 144 days	2011.4
TCGA-FB-A5VM-01A	74 years, male, white, stage:ib, dead, 498 days	2002.6
TCGA-2L-AAQJ-01A	49 years, female, white, stage:iii, dead, 394 days	1999.3
TCGA-RB-AA9M-01A	43 years, male, white, stage:iib, alive, 286 days	1971.6
TCGA-H6-A45N-01A	88 years, female, white, stage:iib, dead, 421 days	1964.9
TCGA-2J-AAB9-01A	71 years, female, white, stage:iib, dead, 627 days	1954.9
TCGA-HV-AA8V-01A	50 years, male, asian, stage:iib, alive, 920 days	1954.1
TCGA-FB-A4P5-01A	69 years, female, white, stage:iib, dead, 179 days	1948.1
TCGA-XN-A8T5-01A	53 years, female, white, stage:ib, alive, 720 days	1943.4
TCGA-HZ-8315-01A	54 years, female, white, stage:iia, dead, 299 days	1942.6
TCGA-HZ-A77Q-01A	55 years, female, white, stage:iib, alive, 33 days	1939.8
TCGA-IB-7886-01A	80 years, male, white, stage:iib, dead, 123 days	1928.4
TCGA-2J-AABE-01A	73 years, male, white, stage:iia, alive, 676 days	1927.9
TCGA-3A-A9IU-01A	65 years, male, white, stage:iib, dead, 458 days	1912.8
TCGA-HZ-8001-01A	69 years, male, white, stage:iii, alive, 706 days	1907.1
TCGA-IB-AAUP-01A	68 years, male, white, stage:iib, alive, 431 days	1901.4
TCGA-IB-AAUO-01A	64 years, female, white, stage:iib, dead, 239 days	1893.6
TCGA-3A-A9I5-01A	58 years, male, white, alive, 1794 days	1890.9
TCGA-HV-A5A4-01A	72 years, female, asian, stage:iia, alive, 232 days	1860.3
TCGA-HZ-8005-01A	81 years, male, white, stage:iib, dead, 120 days	1852.1
TCGA-2L-AAQE-01A	56 years, male, white, stage:iib, dead, 684 days	1849.5
TCGA-IB-7890-01A	73 years, male, stage:ib, dead, 598 days	1846.5
TCGA-FB-AAQ1-01A	49 years, male, white, stage:iib, dead, 123 days	1845.6
TCGA-FB-A545-01A	72 years, female, white, stage:iib, dead, 732 days	1835.1
TCGA-FB-AAPY-01A	71 years, male, white, stage:iib, dead, 1059 days	1821.2
TCGA-F2-7276-01A	64 years, male, white, stage:iib, dead, 216 days	1751.5
TCGA-2J-AABA-01A	55 years, male, white, stage:iib, dead, 607 days	1735.0
TCGA-IB-AAUV-01A	49 years, male, white, stage:iib, alive, 404 days	1728.3
TCGA-F2-A8YN-01A	76 years, male, white, stage:iia, alive, 517 days	1718.5
TCGA-IB-A5ST-01A	64 years, female, white, stage:iib, alive, 635 days	1717.2
TCGA-2J-AABR-01A	60 years, female, white, stage:iia, alive, 438 days	1712.8
TCGA-HZ-7919-01A	52 years, female, white, stage:iib, dead, 593 days	1712.0
TCGA-FB-AAPU-01A	41 years, female, asian, stage:iia, dead, 381 days	1701.5
TCGA-IB-7644-01A	65 years, female, white, stage:iv, dead, 394 days	1700.3
TCGA-3E-AAAY-01A	67 years, male, white, stage:iib, alive, 2285 days	1699.2
TCGA-XN-A8T3-01A	67 years, male, white, stage:ib, alive, 951 days	1695.2
TCGA-IB-7645-01A	44 years, female, stage:iib, dead, 1502 days	1687.7
TCGA-HZ-8636-01A	58 years, female, white, stage:iv, dead, 545 days	1686.3
TCGA-IB-A5SO-01A	71 years, male, white, stage:iib, dead, 365 days	1685.9
TCGA-H6-8124-01A	56 years, female, white, stage:iib, alive, 392 days	1685.7
TCGA-FB-A78T-01A	71 years, female, white, stage:iib, dead, 375 days	1682.4
TCGA-HZ-A8P1-01A	81 years, male, white, stage:ib, alive, 7 days	1677.7
TCGA-RL-AAAS-01A	60 years, female, white, stage:ib, alive, 9 days	1677.3
TCGA-F2-A44H-01A	65 years, male, white, stage:iia, alive, 586 days	1676.8
TCGA-HZ-7289-01A	77 years, male, white, stage:iib, dead, 661 days	1675.1
TCGA-F2-A7TX-01A	77 years, male, white, stage:iib, dead, 95 days	1672.3
TCGA-HZ-7925-01A	66 years, male, white, stage:iib, dead, 614 days	1668.4
TCGA-3E-AAAZ-01A	71 years, male, white, stage:iia, dead, 2182 days	1661.6
TCGA-FB-AAQ6-01A	85 years, male, white, stage:ia, dead, 244 days	1650.3
TCGA-IB-A7M4-01A	81 years, male, white, stage:iib, alive, 483 days	1637.4
TCGA-IB-A6UF-01A	63 years, male, white, stage:iib, alive, 666 days	1616.6
TCGA-IB-7888-01A	66 years, female, black or african american, stage:iia, dead, 1332 days	1612.2
TCGA-S4-A8RP-01A	77 years, female, white, stage:iib, dead, 702 days	1608.9
TCGA-IB-7652-01A	49 years, female, asian, stage:iib, alive, 1116 days	1608.2
TCGA-HZ-A49I-01A	77 years, male, white, stage:iib, dead, 308 days	1578.2
TCGA-XD-AAUG-01A	66 years, female, white, stage:iv, alive, 420 days	1577.4
TCGA-F2-6879-01A	57 years, male, white, stage:iib, dead, 334 days	1573.5
TCGA-IB-7887-01A	62 years, female, white, stage:iib, dead, 110 days	1565.8
TCGA-L1-A7W4-01A	48 years, female, white, stage:iib, dead, 278 days	1562.2
TCGA-HV-A5A5-01A	61 years, female, asian, stage:iib, alive, 289 days	1539.2
TCGA-US-A77E-01A	73 years, male, white, stage:iib, dead, 430 days	1536.7
TCGA-HZ-A4BK-01A	72 years, male, white, stage:iib, alive, 657 days	1535.2
TCGA-XD-AAUH-01A	57 years, female, white, stage:iib, alive, 395 days	1495.8
TCGA-3A-A9I9-01A	67 years, male, white, stage:iia, dead, 634 days	1494.7
TCGA-HZ-A49G-01A	58 years, female, white, stage:iib, alive, 660 days	1490.5
TCGA-HV-A5A3-01A	50 years, male, asian, stage:iia, dead, 128 days	1488.2
TCGA-IB-A5SP-01A	77 years, male, white, stage:iia, alive, 482 days	1487.2
TCGA-US-A774-01A	76 years, female, white, stage:iib, dead, 695 days	1466.0
TCGA-2J-AABI-01A	55 years, female, white, stage:iia, alive, 969 days	1460.9
TCGA-US-A77G-01A	64 years, male, white, stage:iib, dead, 12 days	1460.1
TCGA-IB-8127-01A	59 years, male, white, stage:iib, alive, 522 days	1438.8
TCGA-3A-A9IZ-01A	47 years, male, white, stage:iib, dead, 308 days	1435.7
TCGA-LB-A7SX-01A	74 years, female, black or african american, stage:iib, dead, 393 days	1433.3
TCGA-IB-7651-01A	64 years, female, white, stage:iib, dead, 603 days	1429.7
TCGA-H8-A6C1-01A	53 years, male, white, stage:iia, alive, 671 days	1428.7
TCGA-3A-A9IX-01A	40 years, male, white, stage:ia, alive, 1037 days	1417.0
TCGA-HZ-7922-01A	61 years, female, white, stage:iib, alive, 4 days	1414.9
TCGA-IB-A6UG-01A	65 years, male, white, stage:iib, dead, 41 days	1411.3
TCGA-2L-AAQI-01A	66 years, male, white, stage:iib, dead, 103 days	1392.8
TCGA-IB-7649-01A	73 years, female, stage:iib, dead, 467 days	1392.1
TCGA-LB-A8F3-01A	64 years, female, black or african american, stage:iia, alive, 379 days	1384.5
TCGA-HZ-7926-01A	57 years, male, black or african american, stage:iib, dead, 518 days	1383.2
TCGA-IB-AAUT-01A	65 years, male, white, stage:iib, alive, 287 days	1376.3
TCGA-FB-AAPQ-01A	65 years, male, white, stage:iib, dead, 1130 days	1349.3
TCGA-IB-7891-01A	49 years, female, white, stage:iib, dead, 913 days	1327.4
TCGA-IB-A7LX-01A	57 years, male, white, stage:iib, dead, 250 days	1324.5
TCGA-FB-AAPP-01A	71 years, male, white, stage:iib, dead, 485 days	1319.2
TCGA-HZ-8637-01A	76 years, female, white, stage:iib, dead, 517 days	1311.1
TCGA-IB-7654-01A	80 years, male, white, stage:iib, dead, 476 days	1287.0
TCGA-S4-A8RM-01A	67 years, male, white, stage:iib, alive, 737 days	1271.1
TCGA-HV-AA8X-01A	75 years, female, asian, stage:iib, dead, 532 days	1256.5
TCGA-HZ-7923-01A	65 years, male, white, stage:iia, alive, 314 days	1240.5
TCGA-US-A776-01A	61 years, male, white, stage:iia, alive, 1216 days	1208.8
TCGA-HZ-8317-01A	69 years, female, white, stage:iib, dead, 378 days	1158.7
TCGA-HZ-A49H-01A	68 years, female, white, stage:iib, alive, 491 days	1154.2
TCGA-HZ-7924-01A	60 years, female, white, stage:iia, alive, 840 days	1141.1
TCGA-HZ-7920-01A	71 years, male, white, stage:ib, dead, 236 days	1099.9
TCGA-IB-7897-01A	54 years, female, white, stage:iib, dead, 486 days	1053.4
TCGA-F2-7273-01A	54 years, male, black or african american, stage:iib, dead, 592 days	1034.4
TCGA-HZ-7918-01A	72 years, male, white, stage:iib, alive, 969 days	1028.8
TCGA-IB-AAUW-01A	63 years, female, white, stage:iib, dead, 230 days	1026.5
TCGA-HZ-8002-01A	61 years, male, white, stage:iib, dead, 366 days	1018.5
TCGA-FB-A4P6-01A	54 years, male, white, stage:iib, alive, 767 days	1012.4
TCGA-LB-A9Q5-01A	63 years, female, white, stage:iib, dead, 313 days	996.7
TCGA-3A-A9IV-01A	59 years, female, white, stage:ib, alive, 1103 days	937.2
TCGA-3A-A9IN-01A	62 years, female, white, stage:ib, alive, 2084 days	900.0
TCGA-HZ-8638-01A	84 years, female, white, stage:ia, dead, 151 days	892.7
TCGA-3A-A9IL-01A	39 years, female, white, stage:i, alive, 2741 days	868.2
TCGA-3A-A9IJ-01A	65 years, male, white, stage:ib, alive, 1854 days	842.6
TCGA-HZ-8519-01A	73 years, male, white, stage:ia, alive, 454 days	798.8
TCGA-HZ-8003-01A	65 years, female, white, stage:iib, dead, 596 days	732.4
TCGA-3A-A9IS-01A	67 years, male, white, stage:ib, alive, 998 days	721.9
TCGA-2L-AAQM-01A	52 years, male, white, stage:iib, alive, 1383 days	681.2
TCGA-HV-A7OP-01A	72 years, male, asian, stage:iib, alive, 978 days	678.3
TCGA-3A-A9IR-01A	64 years, female, white, stage:ib, alive, 1542 days	647.4
TCGA-IB-AAUM-01A	76 years, male, white, stage:iib, alive, 8 days	506.3
TCGA-IB-8126-01A	80 years, female, white, stage:iii, alive, 462 days	491.6
TCGA-2J-AABV-01A	74 years, male, white, stage:iib, dead, 652 days	453.5
TCGA-3A-A9IO-01A	56 years, male, white, alive, 1942 days	417.1
TCGA-F2-6880-01A	70 years, male, white, stage:iib, alive, 289 days	148.8
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PANCREATIC CANCER - Protein expressionⁱ A mouse-over function shows sample information and annotation data. Click on an image to view it in a full screen mode. Samples can be filtered based on level of antibody staining by selecting one or several of the following categories: high, medium, low and not detected. The assay and annotation is described here. Note that samples used for immunohistochemistry by the Human Protein Atlas do not correspond to samples in the TCGA dataset.

Antibody stainingⁱ Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high. This score is based on the staining intensity and fraction of stained cells. Read more	Antibody HPA041264	Antibody HPA041271	Antibody CAB002621
Staining
High
Medium
Low
Not detected
Intensity
Strong
Moderate
Weak
Negative
Quantity
>75%
75%-25%
<25%
None
Location
Nuclear
Cytoplasmic/membranous
Cytoplasmic/membranous,nuclear
None
Click images for details