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The primary data page shows the detailed antibody staining in 76 different cell types for each analyzed antibody. In addition, for each cell type, a knowledge-based annotated protein expression score based on all analyzed antibodies is displayed furthest to the right. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
The tissues and cell types can be ordered by organ, cell type or alphabetically. If ordered by organ, the tissues are presented in groups according to functional features. If ordered by cell type, the cells are presented in groups related to origin.
This score describes the level of antibody staining observed in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is based on the staining intensity and fraction of stained cells. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
This score describes a knowledge-based best estimate of the protein expression in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is a result of stringent evaluation of immunohistochemical staining pattern, RNA data from internal and external sources and available protein/gene characterization data. More information can be found in Assays & Annotation.
Summarizing texts describe the staining pattern for each antibody based on staining intensity, fraction of stained cells and subcellular localization. More information can be found in Assays & Annotation.
HPA023370
Most of the normal tissues displayed weak to moderate cytoplasmic positivity. Strong staining was observed in the thyroid gland, oocytes and trophoblastic cells. Bile duct cells, cells in CNS, lymphoid tissues, ovarian and endometrial stromal cells were negative.
HPA023374
Normal tissues displayed weak to moderate cytoplasmic positivity. Cells in seminiferous ducts, oocytes and neuronal cells showed strong cytoplasmic staining. Nuclear positivity was observed in lymphoid cells and nuclear membrane was distinctly stained in heart myocytes. Smooth muscle cells and spleen were negative.
CAB058695
Most of the normal tissues displayed weak to moderate cytoplasmic positivity. Additional nuclear staining was expressed in neuronal cells, Purkinje cells, cardiac and skeletal myocytes. Respiratory epithelia, renal tubules, cells in seminiferous ducts and oocytes showed strong staining. Bile ducts, renal glomeruli, placenta, prostate, spleen, smooth muscles and soft tissues were negative.