Expression of FTL in testis cancer - The Human Protein Atlas

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FTL

SUMMARY

TISSUE

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PATHOLOGY

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TESTIS CANCER - Interactive survival scatter plotⁱ

The Survival Scatter plot shows the clinical status (i.e. dead or alive) for all individuals in the patient cohort, based on the same data that underlies the corresponding Kaplan-Meier plots. Patients that are alive at last time for follow-up are shown in blue and patients who have died during the study are shown in red.

The x-axis shows the expression levels (FPKM) of the investigated gene in the tumor tissue at the time of diagnosis. The y-axis shows the follow-up time after diagnosis (years). Both axes are complimented with kernel density curves demonstrating the data density over the axes. The top density plot shows the expression levels (FPKM) distribution among dead (red) and alive patients (blue). The right density plot shows the data density of the survived years of dead patients with high and low expression levels respectively, stratified using the cutoff indicated by the vertical dashed line through the Survival Scatter plot. This cutoff is automatically defined based on the FPKM cutoff that minimizes the p-score. The cutoff can be changed by dragging the vertical line or by entering a cutoff value in the square labeled "Current cut-off".

Under the Survival Scatter plot the p-score landscape (black curve; left axis) is shown together with dead median separation (red curve; right axis). Dead median separation is the difference in median mRNA expression between patients who have died with high and low expression, respectively. It is calculated as follows: median FPKM expression of dead patients with high expression - median FPKM expression of dead patients with low expression. This is intended to aid the user in visually exploring custom cutoffs and the associated p-scores and dead median separation.

Individual patient data is displayed and can be filtered by clicking on one or more of the category buttons on the top of the page. Categories describing expression level and patient information include: high, low, alive, dead, female, male and tumor stages. The scale of the x-axis can be toggled between linear and log-scale by clicking on the "x log" button. Mouse-over function shows TCGA ID, patient information and mRNA expression (FPKM) for each patient.

& Survival analysisⁱ

FTL is not prognostic in testis cancer

Stage:

Survival analysis

Current cut offⁱ:
Best expression cut offⁱ: 2537.38
Median expressionⁱ: N/A
Median follow up timeⁱ: N/A
P scoreⁱ N/A
5-year survival highⁱ N/A
5-year survival lowⁱ N/A

TCGA RNA samplesⁱ

Average FPKM

2936.6

Number of samples

134

Samples

Sample	Description	FPKM
TCGA-VF-A8AB-01A	31 years, male, black or african american, stage:ia, alive, 760 days	16525.3
TCGA-ZM-AA0H-01A	50 years, male, white, stage:is, alive, 1736 days	13101.5
TCGA-YU-A90S-01A	26 years, male, white, stage:ia, alive, 971 days	11991.4
TCGA-ZM-AA05-01A	36 years, male, white, stage:iic, alive, 1126 days	11784.0
TCGA-XE-AAOB-01A	27 years, male, white, stage:is, dead, 513 days	10081.2
TCGA-2G-AAHA-01A	48 years, male, white, stage:ib, alive, 3349 days	7609.6
TCGA-2G-AAHN-01A	32 years, male, white, stage:i, alive, 6445 days	6918.4
TCGA-X3-A8G4-01A	33 years, male, white, stage:is, alive, 856 days	6765.1
TCGA-XY-A89B-01A	35 years, male, white, stage:ia, alive, 471 days	6270.2
TCGA-ZM-AA0F-01A	35 years, male, white, stage:ia, alive, 681 days	6016.8
TCGA-ZM-AA0E-01A	39 years, male, white, stage:ia, alive, 811 days	5839.1
TCGA-ZM-AA0D-01A	34 years, male, white, stage:ia, alive, 848 days	5766.6
TCGA-2G-AAGG-01A	20 years, male, white, stage:iiic, alive, 2611 days	5564.9
TCGA-2G-AAG9-01A	25 years, male, white, stage:iiib, alive, 2234 days	4779.3
TCGA-YU-A912-01A	34 years, male, black or african american, stage:iiic, alive, 866 days	4473.5
TCGA-4K-AA1H-01A	26 years, male, white, stage:ia, alive, 518 days	4307.1
TCGA-4K-AAAL-01A	31 years, male, white, stage:is, alive, 483 days	4101.6
TCGA-WZ-A8D5-01A	38 years, male, white, alive, 774 days	4057.8
TCGA-2G-AAGZ-01A	27 years, male, white, stage:iiia, alive, 5233 days	4054.1
TCGA-2G-AAFY-01A	24 years, male, white, stage:iia, alive, 1099 days	4004.4
TCGA-2G-AAFH-01A	38 years, male, white, stage:iib, alive, 1375 days	3994.2
TCGA-VF-A8AE-01A	39 years, male, white, stage:ia, alive, 727 days	3945.9
TCGA-2G-AAHC-01A	33 years, male, white, stage:is, alive, 5539 days	3918.9
TCGA-XE-A8H4-01A	23 years, male, white, stage:ia, alive, 559 days	3844.4
TCGA-2G-AAF6-01A	28 years, male, white, stage:is, alive, 3491 days	3723.8
TCGA-2G-AAG5-01A	36 years, male, white, stage:is, alive, 2299 days	3707.2
TCGA-4K-AA1I-01A	26 years, male, white, stage:ia, alive, 3 days	3701.6
TCGA-2G-AAFM-01A	31 years, male, white, stage:iia, alive, 503 days	3698.0
TCGA-2G-AAGF-01A	28 years, male, white, stage:is, alive, 2734 days	3601.2
TCGA-XE-A9SE-01A	35 years, male, white, stage:ia, alive, 708 days	3544.1
TCGA-2G-AAGP-01A	33 years, male, white, stage:iia, alive, 4018 days	3539.6
TCGA-2G-AAFE-01A	37 years, male, white, stage:iia, alive, 4702 days	3483.1
TCGA-VF-A8AD-01A	36 years, male, white, stage:ib, alive, 1006 days	3448.3
TCGA-XE-AAOD-01A	39 years, male, white, stage:ib, alive, 2058 days	3440.2
TCGA-2G-AAKD-01A	18 years, male, white, stage:iii, alive, 6340 days	3363.4
TCGA-2X-A9D5-01A	49 years, male, white, stage:i, alive, 435 days	3186.0
TCGA-2G-AAHL-01A	26 years, male, white, stage:i, alive, 7081 days	3185.8
TCGA-2G-AAFO-01A	33 years, male, white, stage:iia, alive, 685 days	3143.3
TCGA-2G-AAFL-01A	35 years, male, white, stage:ib, alive, 750 days	3113.9
TCGA-2G-AAKG-01A	22 years, male, white, stage:i, alive, 6598 days	3088.6
TCGA-2G-AAFG-01A	30 years, male, white, stage:is, alive, 6183 days	3087.0
TCGA-2G-AAKM-01A	14 years, male, white, stage:ii, dead, 6972 days	3083.6
TCGA-2G-AAEW-01A	31 years, male, white, stage:is, dead, 618 days	3067.0
TCGA-2G-AAHT-01A	32 years, male, white, stage:is, alive, 542 days	3034.0
TCGA-XE-AAO6-01A	47 years, male, white, stage:ia, alive, 240 days	2924.6
TCGA-2G-AAGI-01A	33 years, male, white, stage:is, alive, 3137 days	2756.3
TCGA-2G-AAH8-01A	45 years, male, white, stage:iiic, alive, 2248 days	2732.8
TCGA-XE-AAOF-01A	50 years, male, asian, stage:ia, alive, 1268 days	2723.1
TCGA-2G-AAGT-01A	30 years, male, white, stage:is, alive, 4406 days	2700.5
TCGA-SN-A84X-01A	21 years, male, white, stage:is, alive, 312 days	2668.7
TCGA-WZ-A7V5-01A	27 years, male, white, stage:i, alive, 1061 days	2666.4
TCGA-2G-AAH4-01A	34 years, male, white, stage:ii, alive, 6210 days	2627.7
TCGA-ZM-AA0B-01A	32 years, male, white, stage:ia, alive, 838 days	2585.7
TCGA-XE-AANJ-01A	39 years, male, white, stage:is, alive, 2007 days	2580.5
TCGA-ZM-AA0N-01A	44 years, male, white, stage:ib, alive, 634 days	2574.4
TCGA-YU-A90Y-01A	23 years, male, black or african american, stage:iiic, dead, 17 days	2544.1
TCGA-XE-AAOC-01A	31 years, male, white, stage:ia, alive, 270 days	2530.7
TCGA-YU-AA61-01A	29 years, male, white, stage:is, alive, 864 days	2485.1
TCGA-2G-AAGJ-01A	28 years, male, black or african american, stage:ia, alive, 2938 days	2464.5
TCGA-2G-AAL5-01A	31 years, male, white, stage:i, alive, 7437 days	2432.1
TCGA-YU-AA4L-01A	27 years, male, black or african american, stage:iiic, alive, 1573 days	2394.5
TCGA-XE-AAO4-01A	40 years, male, white, stage:ia, alive, 367 days	2385.1
TCGA-2G-AAFV-01A	31 years, male, white, stage:is, alive, 1389 days	2362.5
TCGA-XE-AANR-01A	24 years, male, white, stage:i, alive, 14 days	2361.7
TCGA-2G-AAH0-01A	30 years, male, white, stage:is, alive, 5477 days	2361.1
TCGA-2G-AAFI-01A	41 years, male, white, stage:ib, alive, 675 days	2358.3
TCGA-2G-AAH2-01A	20 years, male, white, stage:is, alive, 6060 days	2356.1
TCGA-2G-AAF1-01A	28 years, male, asian, stage:is, alive, 1403 days	2320.3
TCGA-2G-AAF8-01A	33 years, male, white, stage:ia, alive, 3911 days	2283.6
TCGA-ZM-AA06-01A	45 years, male, white, stage:ib, alive, 1498 days	2268.8
TCGA-2G-AAG0-01A	23 years, male, white, stage:is, alive, 1529 days	2226.3
TCGA-WZ-A7V4-01A	28 years, male, white, stage:i, alive, 894 days	2217.6
TCGA-2G-AAG3-01A	53 years, male, white, stage:is, alive, 1593 days	2170.9
TCGA-W4-A7U3-01A	26 years, male, white, alive, 149 days	2155.1
TCGA-YU-A90P-01A	25 years, male, white, stage:ia, alive, 2069 days	2089.4
TCGA-2G-AAKL-01A	26 years, male, white, stage:ii, alive, 7023 days	2074.7
TCGA-2G-AAG8-01A	21 years, male, white, stage:ib, alive, 2289 days	2013.5
TCGA-2G-AAL7-01A	32 years, male, white, stage:is, alive, 3991 days	1989.3
TCGA-VF-A8AC-01A	29 years, male, white, stage:ia, alive, 1083 days	1987.3
TCGA-XY-A9T9-01A	37 years, male, white, stage:is, alive, 281 days	1978.7
TCGA-2G-AAH3-01A	20 years, male, white, stage:i, alive, 1822 days	1951.7
TCGA-2G-AAGE-01A	21 years, male, white, stage:is, alive, 2478 days	1949.8
TCGA-2G-AAEX-01A	38 years, male, white, stage:is, alive, 1259 days	1929.3
TCGA-S6-A8JY-01A	27 years, male, white, stage:is, alive, 278 days	1878.3
TCGA-2G-AAGC-01A	28 years, male, white, stage:is, alive, 2585 days	1863.2
TCGA-2G-AAHG-01A	25 years, male, white, stage:i, alive, 1819 days	1852.6
TCGA-2G-AAFZ-01A	32 years, male, white, stage:iii, alive, 1353 days	1835.5
TCGA-SB-A6J6-01A	22 years, male, white, stage:ia, alive, 413 days	1827.4
TCGA-XE-A8H5-01A	29 years, male, stage:is, alive, 1217 days	1826.0
TCGA-2G-AAGK-01A	20 years, male, white, stage:is, alive, 3621 days	1815.8
TCGA-XE-AANV-01A	52 years, male, stage:ib, alive, 1701 days	1798.7
TCGA-2G-AAGN-01A	41 years, male, white, stage:iiib, alive, 3656 days	1793.6
TCGA-2G-AAF4-01A	30 years, male, white, stage:i, alive, 2315 days	1785.0
TCGA-YU-A94I-01A	66 years, male, stage:ia, alive, 536 days	1780.0
TCGA-XE-A8H1-01A	24 years, male, white, stage:is, alive, 209 days	1778.2
TCGA-XE-AAOJ-01A	24 years, male, white, stage:is, alive, 1550 days	1749.7
TCGA-2G-AAGY-01A	28 years, male, white, stage:is, alive, 5329 days	1724.7
TCGA-2G-AAGM-01A	51 years, male, white, stage:is, alive, 3891 days	1723.3
TCGA-VF-A8A9-01A	31 years, male, white, stage:ia, alive, 1119 days	1721.8
TCGA-2G-AAFN-01A	26 years, male, white, stage:iiib, alive, 773 days	1705.1
TCGA-2G-AAFJ-01A	23 years, male, asian, alive, 792 days	1689.0
TCGA-2G-AAGS-01A	39 years, male, white, stage:iiib, alive, 4816 days	1677.3
TCGA-YU-A94D-01A	28 years, male, stage:iiib, alive, 2167 days	1667.1
TCGA-2G-AAG7-01A	33 years, male, white, stage:is, alive, 2475 days	1642.7
TCGA-2G-AALP-01A	43 years, male, white, stage:iiib, alive, 2645 days	1628.8
TCGA-VF-A8A8-01A	18 years, male, white, stage:ia, alive, 1131 days	1613.6
TCGA-2G-AAKH-01A	19 years, male, white, stage:ii, alive, 6862 days	1588.7
TCGA-4K-AA1G-01A	34 years, male, white, stage:is, alive, 436 days	1550.6
TCGA-2X-A9D6-01A	42 years, male, white, stage:i, alive, 607 days	1547.0
TCGA-WZ-A7V3-01A	20 years, male, white, stage:i, alive, 753 days	1535.7
TCGA-SN-A84W-01A	30 years, male, white, stage:is, alive, 293 days	1513.4
TCGA-VF-A8AA-01A	51 years, male, white, stage:i, alive, 1146 days	1480.4
TCGA-YU-A90W-01A	45 years, male, white, stage:ia, alive, 1113 days	1403.8
TCGA-W4-A7U4-01A	23 years, male, white, alive, 738 days	1403.4
TCGA-2G-AAG6-01A	24 years, male, white, stage:is, alive, 2231 days	1393.3
TCGA-W4-A7U2-01A	26 years, male, white, alive, 1263 days	1365.8
TCGA-2G-AAGX-01A	22 years, male, white, stage:ia, alive, 5514 days	1305.4
TCGA-S6-A8JW-01A	37 years, male, white, stage:is, alive, 698 days	1295.1
TCGA-XY-A8S3-01B	24 years, male, white, stage:is, alive, 843 days	1283.0
TCGA-SN-A6IS-01A	26 years, male, white, stage:is, alive, 496 days	1282.8
TCGA-SO-A8JP-01A	29 years, male, white, stage:i, alive, 540 days	1195.7
TCGA-XE-AANI-01A	37 years, male, white, stage:is, alive, 1041 days	1191.9
TCGA-SN-A84Y-01A	18 years, male, white, stage:is, alive, 524 days	1182.3
TCGA-2G-AAGO-01A	41 years, male, white, stage:is, alive, 4026 days	1148.7
TCGA-2G-AAHP-01A	31 years, male, white, stage:is, alive, 5667 days	1121.4
TCGA-2G-AAGW-01A	38 years, male, white, stage:is, alive, 4899 days	1104.2
TCGA-XY-A8S2-01A	67 years, male, white, stage:i, alive, 672 days	1101.6
TCGA-2G-AAGV-01A	23 years, male, white, alive, 4527 days	1041.7
TCGA-XE-AAO3-01A	33 years, male, asian, stage:i, alive, 2857 days	960.8
TCGA-SB-A76C-01A	38 years, male, white, alive, 42 days	912.0
TCGA-2G-AAGA-01A	38 years, male, white, stage:iia, alive, 2439 days	829.3
TCGA-S6-A8JX-01A	27 years, male, white, stage:ib, alive, 552 days	813.1
TCGA-YU-A90Q-01A	21 years, male, stage:ib, alive, 1964 days	786.2
TCGA-XE-AAOL-01A	38 years, male, black or african american, stage:i, alive, 13 days	656.3
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TESTIS CANCER - Protein expressionⁱ A mouse-over function shows sample information and annotation data. Click on an image to view it in a full screen mode. Samples can be filtered based on level of antibody staining by selecting one or several of the following categories: high, medium, low and not detected. The assay and annotation is described here. Note that samples used for immunohistochemistry by the Human Protein Atlas do not correspond to samples in the TCGA dataset.

Antibody stainingⁱ Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high. This score is based on the staining intensity and fraction of stained cells. Read more	Antibody HPA041602	Antibody CAB020769
Staining
High
Medium
Low
Not detected
Intensity
Strong
Moderate
Weak
Negative
Quantity
>75%
75%-25%
<25%
None
Location
Nuclear
Cytoplasmic/membranous
Cytoplasmic/membranous,nuclear
None
Click images for details

Contact

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.