Expression of RPLP0 in colorectal cancer

RECTUM ADENOCARCINOMA (READ) - Interactive survival scatter plotⁱ

The Survival Scatter plot shows the clinical status (i.e. dead or alive) for all individuals in the patient cohort, based on the same data that underlies the corresponding Kaplan-Meier plots. Patients that are alive at last time for follow-up are shown in blue and patients who have died during the study are shown in red.

The x-axis shows the expression levels (FPKM) of the investigated gene in the tumor tissue at the time of diagnosis. The y-axis shows the follow-up time after diagnosis (years). Both axes are complimented with kernel density curves demonstrating the data density over the axes. The top density plot shows the expression levels (FPKM) distribution among dead (red) and alive patients (blue). The right density plot shows the data density of the survived years of dead patients with high and low expression levels respectively, stratified using the cutoff indicated by the vertical dashed line through the Survival Scatter plot. This cutoff is automatically defined based on the FPKM cutoff that minimizes the p-score. The cutoff can be changed by dragging the vertical line or by entering a cutoff value in the square labeled "Current cut-off".

Under the Survival Scatter plot the p-score landscape (black curve; left axis) is shown together with dead median separation (red curve; right axis). Dead median separation is the difference in median mRNA expression between patients who have died with high and low expression, respectively. It is calculated as follows: median FPKM expression of dead patients with high expression - median FPKM expression of dead patients with low expression. This is intended to aid the user in visually exploring custom cutoffs and the associated p-scores and dead median separation.

Individual patient data is displayed and can be filtered by clicking on one or more of the category buttons on the top of the page. Categories describing expression level and patient information include: high, low, alive, dead, female, male and tumor stages. The scale of the x-axis can be toggled between linear and log-scale by clicking on the "x log" button. Mouse-over function shows TCGA ID, patient information and mRNA expression (FPKM) for each patient.

& Survival analysisⁱ

Stage:

Survival analysis

Current cut offⁱ:
Best expression cut offⁱ: 854.2
Median expressionⁱ: N/A
Median follow up timeⁱ: N/A
P scoreⁱ N/A
5-year survival highⁱ N/A
5-year survival lowⁱ N/A

TCGA RNA samplesⁱ

Average FPKM

657.9

Number of samples

159

Samples

Sample	Description	FPKM
TCGA-AG-3609-01A	65 years, female, stage:iiic, alive, 608 days	1801.6
TCGA-AG-3883-01A	69 years, male, stage:i, alive, 31 days	1672.6
TCGA-AG-3574-01A	89 years, female, stage:ii, dead, 1096 days	1488.4
TCGA-AG-3881-01A	83 years, female, stage:iia, alive, 579 days	1459.5
TCGA-AG-3727-01A	78 years, female, stage:iii, alive, 30 days	1375.4
TCGA-AG-A02G-01A	66 years, male, stage:iv, dead, 1185 days	1323.0
TCGA-AG-3591-01A	66 years, female, stage:iia, alive, 1035 days	1255.0
TCGA-AG-3605-01A	85 years, female, stage:iv, alive, 30 days	1247.3
TCGA-AG-3887-01A	68 years, male, stage:iia, alive, 1124 days	1229.0
TCGA-DC-4745-01A	49 years, female, white, stage:iiib, alive, 639 days	1218.0
TCGA-AG-3583-01A	66 years, male, stage:iv, dead, 610 days	1183.6
TCGA-AG-3885-01A	71 years, female, stage:iiib, alive, 546 days	1180.3
TCGA-AG-3894-01A	65 years, male, stage:iia, alive, 426 days	1175.1
TCGA-AG-3587-01A	65 years, male, stage:i, alive, 1400 days	1153.8
TCGA-AG-3608-01A	79 years, female, stage:iia, alive, 485 days	1137.2
TCGA-DC-5337-01A	69 years, male, white, stage:i, alive, 792 days	1093.2
TCGA-AG-3598-01A	69 years, male, stage:iia, alive, 1522 days	1074.6
TCGA-AG-3726-01A	63 years, female, stage:i, alive, 243 days	1056.5
TCGA-AG-3999-01A	61 years, female, stage:iiic, alive, 853 days	1053.2
TCGA-EI-7002-01A	58 years, male, white, stage:iv, alive, 364 days	1021.0
TCGA-AG-3882-01A	66 years, female, stage:i, alive, 608 days	994.7
TCGA-AG-3878-01A	64 years, male, stage:i, alive, 30 days	992.7
TCGA-AG-4005-01A	64 years, male, stage:iv, alive, 427 days	980.5
TCGA-AG-3581-01A	63 years, male, stage:i, alive, 215 days	970.4
TCGA-AG-3611-01A	72 years, male, stage:iia, alive, 424 days	952.5
TCGA-AG-3892-01A	57 years, female, stage:i, alive, 396 days	912.4
TCGA-AG-3896-01A	85 years, female, stage:i, alive, 31 days	907.4
TCGA-DY-A1H8-01A	77 years, female, white, stage:iiia, dead, 992 days	904.2
TCGA-EI-6883-01A	63 years, male, white, stage:iic, alive, 350 days	901.2
TCGA-AG-3600-01A	62 years, male, stage:iiic, alive, 184 days	901.0
TCGA-AG-A023-01A	62 years, female, stage:iv, dead, 1581 days	886.3
TCGA-AG-3594-01A	77 years, male, stage:iia, dead, 61 days	875.5
TCGA-AG-3580-01A	67 years, male, stage:i, alive, 244 days	871.9
TCGA-DC-6682-01A	57 years, male, white, stage:iia, alive, 762 days	871.4
TCGA-AF-5654-01A	73 years, female, white, stage:i, dead, 512 days	859.9
TCGA-AG-A02N-01A	67 years, male, stage:ii, alive, 1885 days	848.5
TCGA-DY-A0XA-01A	57 years, female, white, stage:iia, alive, 3846 days	813.9
TCGA-AG-3599-01A	70 years, male, stage:i, alive, 366 days	802.1
TCGA-EI-6507-01A	60 years, male, white, stage:iia, alive, 607 days	796.3
TCGA-AF-4110-01A	77 years, male, white, stage:iva, alive, 912 days	781.5
TCGA-AF-2691-01A	48 years, female, white, stage:i, alive, 1309 days	771.6
TCGA-AF-2693-01A	75 years, male, white, stage:i, alive, 1155 days	762.6
TCGA-AG-A025-01A	62 years, female, stage:i, alive, 1520 days	748.3
TCGA-AG-A015-01A	64 years, female, stage:i, alive, 1096 days	742.5
TCGA-AG-3586-01A	72 years, female, stage:iii, alive, 31 days	740.3
TCGA-AG-A00C-01A	49 years, female, stage:iiib, alive, 183 days	723.7
TCGA-AG-3575-01A	51 years, male, stage:ii, alive, 365 days	719.9
TCGA-AG-3612-01A	55 years, female, stage:iiib, alive, 608 days	712.4
TCGA-AG-3582-01A	75 years, male, stage:iv, dead, 1096 days	709.6
TCGA-EF-5830-01A	54 years, male, white, stage:iib, alive, 106 days	700.4
TCGA-DC-6155-01A	31 years, female, white, stage:iiia, alive, 425 days	689.9
TCGA-AG-3902-01A	61 years, male, stage:iia, alive, 974 days	688.7
TCGA-AG-3728-01A	73 years, male, stage:iiib, alive, 912 days	671.1
TCGA-EI-6509-01A	53 years, male, white, stage:iiic, alive, 517 days	667.7
TCGA-CL-5918-01A	90 years, female, white, stage:iia, alive, 218 days	667.4
TCGA-AG-3898-01A	61 years, male, stage:iia, alive, 1461 days	663.3
TCGA-AG-A016-01A	55 years, male, stage:iv, alive, 276 days	654.6
TCGA-AG-3893-01A	74 years, male, stage:iiib, alive, 1065 days	654.5
TCGA-CL-4957-01A	79 years, female, dead, 425 days	654.0
TCGA-AG-4007-01A	87 years, male, stage:iv, alive, 31 days	647.3
TCGA-AF-2692-01A	54 years, female, white, stage:iia, alive, 412 days	633.1
TCGA-AH-6549-01A	66 years, male, white, alive, 532 days	629.8
TCGA-AG-A00Y-01A	68 years, male, stage:iia, alive, 700 days	625.3
TCGA-AG-3890-01A	62 years, male, stage:i, alive, 518 days	621.4
TCGA-F5-6861-01A	60 years, female, white, stage:iia, alive, 1160 days	616.1
TCGA-AH-6903-01A	46 years, male, white, stage:iiib, alive, 592 days	614.7
TCGA-DY-A1DD-01A	77 years, female, white, stage:iiib, dead, 1741 days	613.2
TCGA-EI-6510-01A	77 years, female, white, alive, 556 days	608.5
TCGA-AF-6672-01A	43 years, male, white, stage:iv, alive, 748 days	605.8
TCGA-F5-6863-01A	71 years, female, white, stage:iiib, dead, 361 days	602.7
TCGA-AG-A008-01A	50 years, female, stage:i, alive, 424 days	602.2
TCGA-DC-5869-01A	62 years, female, black or african american, stage:iiib, alive, 943 days	601.3
TCGA-G5-6641-01A	67 years, male, white, stage:iiia, alive, 804 days	598.5
TCGA-EI-6917-01A	33 years, male, white, stage:iiia, alive, 531 days	592.5
TCGA-AG-4008-01A	63 years, male, stage:iia, alive, 518 days	591.5
TCGA-AG-A02X-01A	77 years, male, stage:i, alive, 1247 days	590.6
TCGA-EI-7004-01A	37 years, female, white, alive, 257 days	588.9
TCGA-AG-A01N-01A	68 years, female, stage:iv, alive, 943 days	583.1
TCGA-DC-6681-01A	70 years, female, white, stage:iva, alive, 790 days	580.9
TCGA-AG-A020-01A	57 years, female, stage:iii, alive, 31 days	578.7
TCGA-F5-6814-01A	57 years, male, white, stage:iia, alive, 1131 days	573.5
TCGA-AG-A026-01A	66 years, male, stage:ii, dead, 59 days	571.7
TCGA-CI-6620-01A	41 years, female, white, stage:iva, alive, 1009 days	571.0
TCGA-AF-3400-01A	54 years, male, white, stage:iia, alive, 1049 days	571.0
TCGA-CI-6619-01B	41 years, male, white, stage:iv, alive, 184 days	552.3
TCGA-EI-6885-01A	57 years, female, white, stage:iv, alive, 415 days	552.0
TCGA-AH-6643-01A	50 years, male, white, stage:iiic, dead, 1314 days	547.6
TCGA-AG-3732-01A	78 years, female, stage:i, alive, 1003 days	546.9
TCGA-F5-6571-01A	62 years, female, white, stage:iia, alive, 1288 days	546.7
TCGA-AG-3909-01A	69 years, female, stage:iiib, alive, 608 days	537.3
TCGA-CI-6622-01A	74 years, male, white, stage:iib, alive, 1362 days	536.6
TCGA-DT-5265-01A	51 years, male, asian, stage:ii, alive, 384 days	531.8
TCGA-EI-6512-01A	64 years, female, white, stage:iiib, alive, 538 days	531.1
TCGA-G5-6572-01A	56 years, male, white, dead, 1432 days	529.7
TCGA-G5-6235-01A	72 years, male, white, stage:iiib, alive, 1696 days	523.5
TCGA-AH-6897-01A	48 years, male, white, stage:i, alive, 804 days	523.3
TCGA-AF-A56L-01A	48 years, female, black or african american, stage:iiic, alive, 2007 days	523.0
TCGA-AF-2690-01A	77 years, female, white, stage:iiic, dead, 524 days	521.8
TCGA-F5-6864-01A	74 years, female, white, stage:iiib, alive, 379 days	521.4
TCGA-AG-3584-01A	60 years, male, stage:iv, dead, 730 days	519.7
TCGA-DC-6160-01A	68 years, male, white, stage:i, alive, 1339 days	517.5
TCGA-DC-4749-01A	57 years, male, white, stage:i, alive, 762 days	516.7
TCGA-EI-6506-01A	78 years, female, white, stage:iia, alive, 625 days	516.6
TCGA-DC-6683-01A	43 years, male, white, stage:iiib, alive, 762 days	511.6
TCGA-AF-6136-01A	72 years, female, white, stage:iiib, alive, 741 days	505.7
TCGA-AG-3593-01A	72 years, female, stage:iia, alive, 1035 days	502.6
TCGA-AF-3911-01A	48 years, male, white, stage:iiic, alive, 1148 days	500.4
TCGA-AG-4021-01A	84 years, female, stage:iv, dead, 121 days	499.6
TCGA-AF-A56N-01A	47 years, female, black or african american, stage:iia, alive, 360 days	498.4
TCGA-DY-A1DG-01A	75 years, male, white, stage:iva, dead, 1566 days	497.4
TCGA-EI-6513-01A	59 years, male, white, stage:iiib, alive, 497 days	496.1
TCGA-AG-A032-01A	68 years, male, stage:iiib, alive, 1157 days	489.0
TCGA-AF-3913-01A	60 years, male, black or african american, stage:iv, dead, 316 days	484.1
TCGA-AG-4022-01A	59 years, female, stage:ii, alive, 1400 days	472.4
TCGA-AG-4001-01A	74 years, female, stage:iia, alive, 1096 days	471.3
TCGA-DY-A1DC-01A	72 years, female, white, stage:iia, dead, 1258 days	470.6
TCGA-AG-3742-01A	85 years, female, stage:i, alive, 30 days	467.9
TCGA-CI-6623-01B	44 years, male, white, stage:i, alive, 1443 days	462.4
TCGA-F5-6811-01A	72 years, female, white, stage:iia, alive, 979 days	459.1
TCGA-AG-3578-01A	76 years, female, stage:iia, alive, 974 days	458.3
TCGA-DC-6154-01A	57 years, female, white, stage:iva, alive, 365 days	458.1
TCGA-G5-6233-01A	74 years, male, white, dead, 556 days	454.2
TCGA-F5-6813-01A	70 years, male, white, stage:iiic, dead, 598 days	453.9
TCGA-AH-6544-01A	60 years, male, white, alive, 1173 days	445.6
TCGA-DC-6157-01A	48 years, male, black or african american, stage:i, alive, 1581 days	445.3
TCGA-EF-5831-01A	72 years, male, white, stage:iia, alive, 127 days	439.0
TCGA-AG-3592-01A	68 years, male, stage:iia, alive, 1035 days	437.0
TCGA-DY-A1DE-01A	56 years, female, white, stage:iia, alive, 3932 days	436.8
TCGA-AG-A036-01A	71 years, male, stage:iii, alive, 3562 days	436.4
TCGA-AG-A014-01A	86 years, male, stage:i, alive, 485 days	433.7
TCGA-EI-6884-01A	71 years, male, white, stage:iiia, alive, 328 days	429.0
TCGA-AG-3731-01A	65 years, male, stage:iv, alive, 1126 days	428.9
TCGA-EI-6508-01A	48 years, female, white, stage:iiib, alive, 636 days	428.5
TCGA-CI-6621-01A	63 years, male, white, stage:iiib, alive, 419 days	426.1
TCGA-AG-A01J-01A	59 years, female, stage:iia, alive, 31 days	421.5
TCGA-EI-6511-01A	52 years, male, white, stage:iiib, alive, 482 days	419.0
TCGA-AF-A56K-01A	56 years, male, black or african american, stage:iia, alive, 2635 days	417.3
TCGA-AG-3725-01A	90 years, female, stage:iii, alive, 638 days	411.7
TCGA-AF-6655-01A	66 years, male, white, stage:iiia, alive, 609 days	408.6
TCGA-AG-A00H-01A	75 years, male, stage:iia, alive, 790 days	407.2
TCGA-AH-6644-01A	73 years, male, white, alive, 838 days	404.3
TCGA-AG-3901-01A	67 years, female, stage:iiib, alive, 761 days	401.7
TCGA-AG-A011-01A	80 years, male, stage:iia, alive, 1126 days	398.7
TCGA-EI-6881-01A	60 years, male, white, stage:iiia, alive, 499 days	396.1
TCGA-F5-6812-01A	67 years, male, white, stage:iia, alive, 1110 days	391.1
TCGA-AF-2687-01A	57 years, male, white, stage:iiic, alive, 1427 days	391.1
TCGA-EI-6882-01A	59 years, male, white, stage:iia, alive, 262 days	375.4
TCGA-BM-6198-01A	73 years, male, white, stage:iiib, alive, 646 days	372.8
TCGA-EI-6514-01A	59 years, female, white, stage:iia, alive, 496 days	341.7
TCGA-CL-5917-01A	71 years, female, white, stage:iiic, alive, 2376 days	317.0
TCGA-AH-6547-01A	79 years, female, white, dead, 76 days	300.3
TCGA-F5-6465-01A	64 years, female, white, stage:iia, alive, 1506 days	299.8
TCGA-F5-6464-01A	77 years, female, white, stage:iiic, dead, 303 days	297.3
TCGA-F5-6702-01A	71 years, male, white, stage:iva, alive, 869 days	281.9
TCGA-DC-6156-01A	62 years, male, white, stage:iva, alive, 943 days	275.3
TCGA-DC-6158-01A	70 years, male, white, stage:i, dead, 334 days	274.7
TCGA-CI-6624-01C	53 years, female, white, stage:i, alive, 1466 days	267.3
TCGA-DY-A1DF-01A	73 years, female, white, stage:iiic, dead, 734 days	242.6
TCGA-AG-A002-01A	35 years, male, stage:i, alive, 638 days	222.4
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