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The primary data page shows the detailed antibody staining in 76 different cell types for each analyzed antibody. In addition, for each cell type, a knowledge-based annotated protein expression score based on all analyzed antibodies is displayed furthest to the right. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
The tissues and cell types can be ordered by organ, cell type or alphabetically. If ordered by organ, the tissues are presented in groups according to functional features. If ordered by cell type, the cells are presented in groups related to origin.
This score describes the level of antibody staining observed in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is based on the staining intensity and fraction of stained cells. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
This score describes a knowledge-based best estimate of the protein expression in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is a result of stringent evaluation of immunohistochemical staining pattern, RNA data from internal and external sources and available protein/gene characterization data. More information can be found in Assays & Annotation.
Summarizing texts describe the staining pattern for each antibody based on staining intensity, fraction of stained cells and subcellular localization. More information can be found in Assays & Annotation.
HPA030131
Trophoblastic cells in placenta displayed strong cytoplasmic immunoreactivity. Moderate nuclear positivity was observed in some squamous epithelium, nasopharynx, epididymis, neuronal cells in CNS and most endocrine tissues. Remaining normal tissues were negative or weakly stained.
HPA030132
Strong cytoplasmic positivity was observed in pancreatic islet cells, stratum granulosum of skin and subsets of neuronal cells. Leydig cells, adrenal cortex, most squamous epithelium and skeletal muscle showed moderate cytoplasmic staining. Remaining normal tissues were negative or weakly stained.
HPA030133
Normal tissues showed weak to moderate cytoplasmic staining. Respiratory epithelium of nasopharynx, trophoblastic cells, epidermal cells of skin, thyroid and colon exhibited strong cytoplasmic staining. Bile duct cells, islet cells, ovary, glial cells and the lymphoid tissues were negative or weakly stained. Stroma cells were negative.
HPA030134
Strong cytoplasmic positivity was observed in esophagus and subset of cells in adrenal cortex and neuronal cells. Gastric glands, renal tubules, leydig cells in testis, respiratory epithelia, skeletal and heart myocytes were moderately stained. Remaining normal cells were weakly stained or negative.