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The primary data page shows the detailed antibody staining in 76 different cell types for each analyzed antibody. In addition, for each cell type, a knowledge-based annotated protein expression score based on all analyzed antibodies is displayed furthest to the right. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
The tissues and cell types can be ordered by organ, cell type or alphabetically. If ordered by organ, the tissues are presented in groups according to functional features. If ordered by cell type, the cells are presented in groups related to origin.
This score describes the level of antibody staining observed in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is based on the staining intensity and fraction of stained cells. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
This score describes a knowledge-based best estimate of the protein expression in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is a result of stringent evaluation of immunohistochemical staining pattern, RNA data from internal and external sources and available protein/gene characterization data. More information can be found in Assays & Annotation.
Summarizing texts describe the staining pattern for each antibody based on staining intensity, fraction of stained cells and subcellular localization. More information can be found in Assays & Annotation.
HPA030212
Most of the normal tissues displayed weak to moderate cytoplasmic positivity accompanied with membranous immunoreactivity. Nuclear staining was observed in for example lung alveolar cells type 2 and squamous epithelia. Cells of red pulp of spleen and bone marrow poietic cells showed strong positivity.
HPA030213
Most of the normal tissues displayed moderate cytoplasmic immunoreactivity, often combined with membranous positivity. Hepatocytes, glial cells, ovarian and endometrial stroma were weakly stained or negative.
HPA030214
Most of the normal tissues displayed weak to moderate cytoplasmic positivity. Cells in seminiferus ducts and subsets of neuronal cells were strongly stained. Skin, lymphoid tissues, myocytes and pancreatic islets were negative.
HPA030215
Most normal tissues displayed moderate to strong cytoplasmic immunoreactivity, often with a granular pattern. Strongest staining was observed in endocrine glands and the male genital tract.
CAB013496
Most normal tissues displayed weak cytoplasmic and membranous positivity or were negative. Moderate neuropil positivity in cerebellum. Trophoblastic cells, intercalated ducts in pancreas, bile ducts, thyroid and smooth muscle showed moderate to strong positivity.