Expression of RPS6 in colorectal cancer

RECTUM ADENOCARCINOMA (READ) - Interactive survival scatter plotⁱ

The Survival Scatter plot shows the clinical status (i.e. dead or alive) for all individuals in the patient cohort, based on the same data that underlies the corresponding Kaplan-Meier plots. Patients that are alive at last time for follow-up are shown in blue and patients who have died during the study are shown in red.

The x-axis shows the expression levels (FPKM) of the investigated gene in the tumor tissue at the time of diagnosis. The y-axis shows the follow-up time after diagnosis (years). Both axes are complimented with kernel density curves demonstrating the data density over the axes. The top density plot shows the expression levels (FPKM) distribution among dead (red) and alive patients (blue). The right density plot shows the data density of the survived years of dead patients with high and low expression levels respectively, stratified using the cutoff indicated by the vertical dashed line through the Survival Scatter plot. This cutoff is automatically defined based on the FPKM cutoff that minimizes the p-score. The cutoff can be changed by dragging the vertical line or by entering a cutoff value in the square labeled "Current cut-off".

Under the Survival Scatter plot the p-score landscape (black curve; left axis) is shown together with dead median separation (red curve; right axis). Dead median separation is the difference in median mRNA expression between patients who have died with high and low expression, respectively. It is calculated as follows: median FPKM expression of dead patients with high expression - median FPKM expression of dead patients with low expression. This is intended to aid the user in visually exploring custom cutoffs and the associated p-scores and dead median separation.

Individual patient data is displayed and can be filtered by clicking on one or more of the category buttons on the top of the page. Categories describing expression level and patient information include: high, low, alive, dead, female, male and tumor stages. The scale of the x-axis can be toggled between linear and log-scale by clicking on the "x log" button. Mouse-over function shows TCGA ID, patient information and mRNA expression (FPKM) for each patient.

& Survival analysisⁱ

Stage:

Survival analysis

Current cut offⁱ:
Best expression cut offⁱ: 1367.64
Median expressionⁱ: N/A
Median follow up timeⁱ: N/A
P scoreⁱ N/A
5-year survival highⁱ N/A
5-year survival lowⁱ N/A

TCGA RNA samplesⁱ

Average FPKM

1235.1

Number of samples

159

Samples

Sample	Description	FPKM
TCGA-DC-4745-01A	49 years, female, white, stage:iiib, alive, 639 days	4397.9
TCGA-AG-3605-01A	85 years, female, stage:iv, alive, 30 days	4162.7
TCGA-AG-3598-01A	69 years, male, stage:iia, alive, 1522 days	4098.7
TCGA-AG-3881-01A	83 years, female, stage:iia, alive, 579 days	3672.5
TCGA-AG-3591-01A	66 years, female, stage:iia, alive, 1035 days	3585.7
TCGA-AG-3612-01A	55 years, female, stage:iiib, alive, 608 days	3061.2
TCGA-EI-6883-01A	63 years, male, white, stage:iic, alive, 350 days	2633.7
TCGA-AG-3611-01A	72 years, male, stage:iia, alive, 424 days	2496.1
TCGA-AG-3583-01A	66 years, male, stage:iv, dead, 610 days	2172.3
TCGA-DC-5337-01A	69 years, male, white, stage:i, alive, 792 days	2163.8
TCGA-DY-A1H8-01A	77 years, female, white, stage:iiia, dead, 992 days	2054.0
TCGA-DC-6682-01A	57 years, male, white, stage:iia, alive, 762 days	1994.7
TCGA-AF-4110-01A	77 years, male, white, stage:iva, alive, 912 days	1975.3
TCGA-AF-3913-01A	60 years, male, black or african american, stage:iv, dead, 316 days	1968.5
TCGA-AG-A023-01A	62 years, female, stage:iv, dead, 1581 days	1954.7
TCGA-AG-3896-01A	85 years, female, stage:i, alive, 31 days	1936.0
TCGA-AF-3400-01A	54 years, male, white, stage:iia, alive, 1049 days	1919.2
TCGA-AG-3575-01A	51 years, male, stage:ii, alive, 365 days	1876.8
TCGA-AG-3883-01A	69 years, male, stage:i, alive, 31 days	1819.2
TCGA-AG-3894-01A	65 years, male, stage:iia, alive, 426 days	1771.3
TCGA-F5-6861-01A	60 years, female, white, stage:iia, alive, 1160 days	1745.6
TCGA-AF-6655-01A	66 years, male, white, stage:iiia, alive, 609 days	1724.0
TCGA-AG-3587-01A	65 years, male, stage:i, alive, 1400 days	1714.3
TCGA-AG-3887-01A	68 years, male, stage:iia, alive, 1124 days	1711.2
TCGA-AG-3725-01A	90 years, female, stage:iii, alive, 638 days	1696.9
TCGA-AG-3574-01A	89 years, female, stage:ii, dead, 1096 days	1690.9
TCGA-AG-3999-01A	61 years, female, stage:iiic, alive, 853 days	1683.2
TCGA-EF-5831-01A	72 years, male, white, stage:iia, alive, 127 days	1669.4
TCGA-AG-3608-01A	79 years, female, stage:iia, alive, 485 days	1653.9
TCGA-AG-3892-01A	57 years, female, stage:i, alive, 396 days	1641.4
TCGA-AH-6643-01A	50 years, male, white, stage:iiic, dead, 1314 days	1635.5
TCGA-EI-7002-01A	58 years, male, white, stage:iv, alive, 364 days	1635.1
TCGA-AF-2691-01A	48 years, female, white, stage:i, alive, 1309 days	1567.4
TCGA-AG-3592-01A	68 years, male, stage:iia, alive, 1035 days	1558.5
TCGA-AF-6136-01A	72 years, female, white, stage:iiib, alive, 741 days	1554.9
TCGA-F5-6813-01A	70 years, male, white, stage:iiic, dead, 598 days	1543.4
TCGA-AG-3582-01A	75 years, male, stage:iv, dead, 1096 days	1503.8
TCGA-EI-6917-01A	33 years, male, white, stage:iiia, alive, 531 days	1495.5
TCGA-G5-6233-01A	74 years, male, white, dead, 556 days	1495.2
TCGA-DC-5869-01A	62 years, female, black or african american, stage:iiib, alive, 943 days	1487.3
TCGA-DY-A0XA-01A	57 years, female, white, stage:iia, alive, 3846 days	1483.3
TCGA-AG-3580-01A	67 years, male, stage:i, alive, 244 days	1448.3
TCGA-AF-2690-01A	77 years, female, white, stage:iiic, dead, 524 days	1438.9
TCGA-AG-3581-01A	63 years, male, stage:i, alive, 215 days	1438.3
TCGA-EI-7004-01A	37 years, female, white, alive, 257 days	1408.3
TCGA-BM-6198-01A	73 years, male, white, stage:iiib, alive, 646 days	1392.7
TCGA-EF-5830-01A	54 years, male, white, stage:iib, alive, 106 days	1384.5
TCGA-F5-6864-01A	74 years, female, white, stage:iiib, alive, 379 days	1384.1
TCGA-DC-6155-01A	31 years, female, white, stage:iiia, alive, 425 days	1378.5
TCGA-AG-3594-01A	77 years, male, stage:iia, dead, 61 days	1370.4
TCGA-AF-6672-01A	43 years, male, white, stage:iv, alive, 748 days	1364.9
TCGA-AG-3609-01A	65 years, female, stage:iiic, alive, 608 days	1344.6
TCGA-CL-5918-01A	90 years, female, white, stage:iia, alive, 218 days	1325.3
TCGA-AG-3902-01A	61 years, male, stage:iia, alive, 974 days	1319.1
TCGA-AG-3898-01A	61 years, male, stage:iia, alive, 1461 days	1290.6
TCGA-EI-6884-01A	71 years, male, white, stage:iiia, alive, 328 days	1289.2
TCGA-AF-3911-01A	48 years, male, white, stage:iiic, alive, 1148 days	1287.4
TCGA-AG-A00C-01A	49 years, female, stage:iiib, alive, 183 days	1274.1
TCGA-AG-A008-01A	50 years, female, stage:i, alive, 424 days	1265.5
TCGA-AF-2693-01A	75 years, male, white, stage:i, alive, 1155 days	1263.3
TCGA-AG-4001-01A	74 years, female, stage:iia, alive, 1096 days	1240.9
TCGA-AG-3599-01A	70 years, male, stage:i, alive, 366 days	1220.6
TCGA-AG-3728-01A	73 years, male, stage:iiib, alive, 912 days	1218.2
TCGA-AG-4005-01A	64 years, male, stage:iv, alive, 427 days	1217.6
TCGA-EI-6509-01A	53 years, male, white, stage:iiic, alive, 517 days	1215.7
TCGA-DC-6154-01A	57 years, female, white, stage:iva, alive, 365 days	1202.1
TCGA-F5-6863-01A	71 years, female, white, stage:iiib, dead, 361 days	1194.3
TCGA-F5-6571-01A	62 years, female, white, stage:iia, alive, 1288 days	1177.5
TCGA-AG-A015-01A	64 years, female, stage:i, alive, 1096 days	1164.2
TCGA-AG-4008-01A	63 years, male, stage:iia, alive, 518 days	1162.8
TCGA-AG-3586-01A	72 years, female, stage:iii, alive, 31 days	1147.4
TCGA-EI-6881-01A	60 years, male, white, stage:iiia, alive, 499 days	1134.2
TCGA-G5-6641-01A	67 years, male, white, stage:iiia, alive, 804 days	1121.1
TCGA-AG-3885-01A	71 years, female, stage:iiib, alive, 546 days	1115.9
TCGA-AG-A02G-01A	66 years, male, stage:iv, dead, 1185 days	1106.0
TCGA-AH-6644-01A	73 years, male, white, alive, 838 days	1101.7
TCGA-AG-4022-01A	59 years, female, stage:ii, alive, 1400 days	1093.4
TCGA-DY-A1DC-01A	72 years, female, white, stage:iia, dead, 1258 days	1085.9
TCGA-DY-A1DG-01A	75 years, male, white, stage:iva, dead, 1566 days	1081.3
TCGA-AG-3732-01A	78 years, female, stage:i, alive, 1003 days	1059.8
TCGA-AG-4007-01A	87 years, male, stage:iv, alive, 31 days	1052.2
TCGA-AG-A00Y-01A	68 years, male, stage:iia, alive, 700 days	1049.1
TCGA-DC-6157-01A	48 years, male, black or african american, stage:i, alive, 1581 days	1029.0
TCGA-G5-6572-01A	56 years, male, white, dead, 1432 days	1026.6
TCGA-AG-3909-01A	69 years, female, stage:iiib, alive, 608 days	1024.7
TCGA-AF-5654-01A	73 years, female, white, stage:i, dead, 512 days	1018.7
TCGA-CI-6622-01A	74 years, male, white, stage:iib, alive, 1362 days	1000.6
TCGA-AG-3901-01A	67 years, female, stage:iiib, alive, 761 days	993.7
TCGA-DY-A1DE-01A	56 years, female, white, stage:iia, alive, 3932 days	990.1
TCGA-EI-6507-01A	60 years, male, white, stage:iia, alive, 607 days	986.1
TCGA-AG-A02X-01A	77 years, male, stage:i, alive, 1247 days	984.6
TCGA-AF-A56N-01A	47 years, female, black or african american, stage:iia, alive, 360 days	980.6
TCGA-AG-A032-01A	68 years, male, stage:iiib, alive, 1157 days	962.4
TCGA-AG-A036-01A	71 years, male, stage:iii, alive, 3562 days	952.9
TCGA-AG-A016-01A	55 years, male, stage:iv, alive, 276 days	941.0
TCGA-AG-3600-01A	62 years, male, stage:iiic, alive, 184 days	940.5
TCGA-CI-6623-01B	44 years, male, white, stage:i, alive, 1443 days	928.2
TCGA-DC-6681-01A	70 years, female, white, stage:iva, alive, 790 days	923.0
TCGA-AH-6903-01A	46 years, male, white, stage:iiib, alive, 592 days	921.6
TCGA-AG-3742-01A	85 years, female, stage:i, alive, 30 days	914.3
TCGA-AG-3878-01A	64 years, male, stage:i, alive, 30 days	910.5
TCGA-AG-3584-01A	60 years, male, stage:iv, dead, 730 days	908.1
TCGA-F5-6814-01A	57 years, male, white, stage:iia, alive, 1131 days	906.9
TCGA-AG-3593-01A	72 years, female, stage:iia, alive, 1035 days	906.5
TCGA-AG-3890-01A	62 years, male, stage:i, alive, 518 days	894.5
TCGA-DC-6683-01A	43 years, male, white, stage:iiib, alive, 762 days	892.9
TCGA-AG-A020-01A	57 years, female, stage:iii, alive, 31 days	886.9
TCGA-EI-6513-01A	59 years, male, white, stage:iiib, alive, 497 days	879.1
TCGA-AG-A025-01A	62 years, female, stage:i, alive, 1520 days	867.6
TCGA-AG-3727-01A	78 years, female, stage:iii, alive, 30 days	867.1
TCGA-AG-3726-01A	63 years, female, stage:i, alive, 243 days	864.0
TCGA-AG-3893-01A	74 years, male, stage:iiib, alive, 1065 days	854.3
TCGA-AG-3578-01A	76 years, female, stage:iia, alive, 974 days	849.6
TCGA-CI-6620-01A	41 years, female, white, stage:iva, alive, 1009 days	830.1
TCGA-AG-A011-01A	80 years, male, stage:iia, alive, 1126 days	827.7
TCGA-AF-A56K-01A	56 years, male, black or african american, stage:iia, alive, 2635 days	825.1
TCGA-F5-6811-01A	72 years, female, white, stage:iia, alive, 979 days	824.8
TCGA-DT-5265-01A	51 years, male, asian, stage:ii, alive, 384 days	822.2
TCGA-AG-A01N-01A	68 years, female, stage:iv, alive, 943 days	805.9
TCGA-DY-A1DD-01A	77 years, female, white, stage:iiib, dead, 1741 days	803.3
TCGA-DC-6160-01A	68 years, male, white, stage:i, alive, 1339 days	795.4
TCGA-AH-6897-01A	48 years, male, white, stage:i, alive, 804 days	793.9
TCGA-EI-6885-01A	57 years, female, white, stage:iv, alive, 415 days	788.8
TCGA-G5-6235-01A	72 years, male, white, stage:iiib, alive, 1696 days	788.7
TCGA-EI-6510-01A	77 years, female, white, alive, 556 days	787.6
TCGA-AG-3882-01A	66 years, female, stage:i, alive, 608 days	786.5
TCGA-AF-A56L-01A	48 years, female, black or african american, stage:iiic, alive, 2007 days	784.9
TCGA-AG-A02N-01A	67 years, male, stage:ii, alive, 1885 days	783.3
TCGA-EI-6511-01A	52 years, male, white, stage:iiib, alive, 482 days	759.5
TCGA-F5-6812-01A	67 years, male, white, stage:iia, alive, 1110 days	750.7
TCGA-EI-6506-01A	78 years, female, white, stage:iia, alive, 625 days	745.0
TCGA-CI-6621-01A	63 years, male, white, stage:iiib, alive, 419 days	744.2
TCGA-AG-A00H-01A	75 years, male, stage:iia, alive, 790 days	737.2
TCGA-EI-6512-01A	64 years, female, white, stage:iiib, alive, 538 days	733.1
TCGA-F5-6702-01A	71 years, male, white, stage:iva, alive, 869 days	728.1
TCGA-F5-6465-01A	64 years, female, white, stage:iia, alive, 1506 days	709.6
TCGA-AH-6544-01A	60 years, male, white, alive, 1173 days	704.0
TCGA-EI-6514-01A	59 years, female, white, stage:iia, alive, 496 days	702.0
TCGA-AG-A014-01A	86 years, male, stage:i, alive, 485 days	701.7
TCGA-AF-2687-01A	57 years, male, white, stage:iiic, alive, 1427 days	691.4
TCGA-CI-6619-01B	41 years, male, white, stage:iv, alive, 184 days	691.3
TCGA-AF-2692-01A	54 years, female, white, stage:iia, alive, 412 days	676.1
TCGA-DC-4749-01A	57 years, male, white, stage:i, alive, 762 days	665.6
TCGA-AG-A01J-01A	59 years, female, stage:iia, alive, 31 days	646.6
TCGA-CL-5917-01A	71 years, female, white, stage:iiic, alive, 2376 days	644.3
TCGA-F5-6464-01A	77 years, female, white, stage:iiic, dead, 303 days	635.6
TCGA-AH-6549-01A	66 years, male, white, alive, 532 days	616.1
TCGA-DC-6156-01A	62 years, male, white, stage:iva, alive, 943 days	595.0
TCGA-EI-6508-01A	48 years, female, white, stage:iiib, alive, 636 days	573.3
TCGA-AH-6547-01A	79 years, female, white, dead, 76 days	563.4
TCGA-AG-3731-01A	65 years, male, stage:iv, alive, 1126 days	557.6
TCGA-EI-6882-01A	59 years, male, white, stage:iia, alive, 262 days	486.3
TCGA-AG-A026-01A	66 years, male, stage:ii, dead, 59 days	477.0
TCGA-AG-A002-01A	35 years, male, stage:i, alive, 638 days	456.5
TCGA-CL-4957-01A	79 years, female, dead, 425 days	441.3
TCGA-DC-6158-01A	70 years, male, white, stage:i, dead, 334 days	405.9
TCGA-AG-4021-01A	84 years, female, stage:iv, dead, 121 days	395.5
TCGA-CI-6624-01C	53 years, female, white, stage:i, alive, 1466 days	367.2
TCGA-DY-A1DF-01A	73 years, female, white, stage:iiic, dead, 734 days	302.2
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