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The primary data page shows the detailed antibody staining in 76 different cell types for each analyzed antibody. In addition, for each cell type, a knowledge-based annotated protein expression score based on all analyzed antibodies is displayed furthest to the right. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
The tissues and cell types can be ordered by organ, cell type or alphabetically. If ordered by organ, the tissues are presented in groups according to functional features. If ordered by cell type, the cells are presented in groups related to origin.
This score describes the level of antibody staining observed in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is based on the staining intensity and fraction of stained cells. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
This score describes a knowledge-based best estimate of the protein expression in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is a result of stringent evaluation of immunohistochemical staining pattern, RNA data from internal and external sources and available protein/gene characterization data. More information can be found in Assays & Annotation.
Summarizing texts describe the staining pattern for each antibody based on staining intensity, fraction of stained cells and subcellular localization. More information can be found in Assays & Annotation.
HPA018990
A majority of normal tissues displayed moderate to strong cytoplasmic immunoreactivity with a granular pattern. Cells of the CNS were weakly stained.
HPA018993
Most of the normal tissues showed weak to moderate cytoplasmic positivity. Strong positivity in granular pattern was seen in cells of gastro-intestinal tract, adrenal gland, tubular cells of kidney and heart muscle. Lymphoid tissues and squamous epithelia were negative.
HPA018996
Most normal tissues were negative. Strong cytoplasmic positivity was observed in gastrointestinal tract and subsets of tubular cells in kidney. Testis, airway epithelia, urinary bladder and trophoblastic cells showed moderate cytoplasmic positivity.
HPA024089
Moderate to strong cytoplasmic positivity with a granular pattern was observed in most normal tissues. Gastrointestinal cells, renal tubules and heart muscle among other showed strong immunoreactivity.