Expression of B2M in colorectal cancer - The Human Protein Atlas

RECTUM ADENOCARCINOMA (READ) - Interactive survival scatter plotⁱ

The Survival Scatter plot shows the clinical status (i.e. dead or alive) for all individuals in the patient cohort, based on the same data that underlies the corresponding Kaplan-Meier plots. Patients that are alive at last time for follow-up are shown in blue and patients who have died during the study are shown in red.

The x-axis shows the expression levels (FPKM) of the investigated gene in the tumor tissue at the time of diagnosis. The y-axis shows the follow-up time after diagnosis (years). Both axes are complimented with kernel density curves demonstrating the data density over the axes. The top density plot shows the expression levels (FPKM) distribution among dead (red) and alive patients (blue). The right density plot shows the data density of the survived years of dead patients with high and low expression levels respectively, stratified using the cutoff indicated by the vertical dashed line through the Survival Scatter plot. This cutoff is automatically defined based on the FPKM cutoff that minimizes the p-score. The cutoff can be changed by dragging the vertical line or by entering a cutoff value in the square labeled "Current cut-off".

Under the Survival Scatter plot the p-score landscape (black curve; left axis) is shown together with dead median separation (red curve; right axis). Dead median separation is the difference in median mRNA expression between patients who have died with high and low expression, respectively. It is calculated as follows: median FPKM expression of dead patients with high expression - median FPKM expression of dead patients with low expression. This is intended to aid the user in visually exploring custom cutoffs and the associated p-scores and dead median separation.

Individual patient data is displayed and can be filtered by clicking on one or more of the category buttons on the top of the page. Categories describing expression level and patient information include: high, low, alive, dead, female, male and tumor stages. The scale of the x-axis can be toggled between linear and log-scale by clicking on the "x log" button. Mouse-over function shows TCGA ID, patient information and mRNA expression (FPKM) for each patient.

& Survival analysisⁱ

Stage:

Survival analysis

Current cut offⁱ:
Best expression cut offⁱ: 385.12
Median expressionⁱ: N/A
Median follow up timeⁱ: N/A
P scoreⁱ N/A
5-year survival highⁱ N/A
5-year survival lowⁱ N/A

TCGA RNA samplesⁱ

Average FPKM

581.4

Number of samples

159

Samples

Sample	Description	FPKM
TCGA-AG-3575-01A	51 years, male, stage:ii, alive, 365 days	3086.3
TCGA-AF-3400-01A	54 years, male, white, stage:iia, alive, 1049 days	1804.4
TCGA-AG-3892-01A	57 years, female, stage:i, alive, 396 days	1337.9
TCGA-DC-5337-01A	69 years, male, white, stage:i, alive, 792 days	1328.8
TCGA-AH-6547-01A	79 years, female, white, dead, 76 days	1299.4
TCGA-AF-2690-01A	77 years, female, white, stage:iiic, dead, 524 days	1295.2
TCGA-AG-3594-01A	77 years, male, stage:iia, dead, 61 days	1261.5
TCGA-DT-5265-01A	51 years, male, asian, stage:ii, alive, 384 days	1214.5
TCGA-G5-6235-01A	72 years, male, white, stage:iiib, alive, 1696 days	1182.1
TCGA-AF-4110-01A	77 years, male, white, stage:iva, alive, 912 days	1151.7
TCGA-F5-6464-01A	77 years, female, white, stage:iiic, dead, 303 days	1122.9
TCGA-AG-3611-01A	72 years, male, stage:iia, alive, 424 days	1068.3
TCGA-AG-4022-01A	59 years, female, stage:ii, alive, 1400 days	1053.4
TCGA-AG-3599-01A	70 years, male, stage:i, alive, 366 days	980.3
TCGA-F5-6811-01A	72 years, female, white, stage:iia, alive, 979 days	972.7
TCGA-CI-6624-01C	53 years, female, white, stage:i, alive, 1466 days	971.1
TCGA-DY-A1DE-01A	56 years, female, white, stage:iia, alive, 3932 days	970.9
TCGA-AG-3608-01A	79 years, female, stage:iia, alive, 485 days	953.7
TCGA-DC-6156-01A	62 years, male, white, stage:iva, alive, 943 days	951.1
TCGA-AG-3902-01A	61 years, male, stage:iia, alive, 974 days	898.7
TCGA-EI-6511-01A	52 years, male, white, stage:iiib, alive, 482 days	896.3
TCGA-AG-3586-01A	72 years, female, stage:iii, alive, 31 days	894.9
TCGA-EI-6506-01A	78 years, female, white, stage:iia, alive, 625 days	888.1
TCGA-AF-2687-01A	57 years, male, white, stage:iiic, alive, 1427 days	883.6
TCGA-AF-2691-01A	48 years, female, white, stage:i, alive, 1309 days	877.6
TCGA-AG-3598-01A	69 years, male, stage:iia, alive, 1522 days	857.9
TCGA-AG-3580-01A	67 years, male, stage:i, alive, 244 days	848.4
TCGA-DC-6158-01A	70 years, male, white, stage:i, dead, 334 days	829.6
TCGA-DC-6160-01A	68 years, male, white, stage:i, alive, 1339 days	824.6
TCGA-F5-6465-01A	64 years, female, white, stage:iia, alive, 1506 days	818.5
TCGA-AG-3731-01A	65 years, male, stage:iv, alive, 1126 days	816.8
TCGA-AF-2693-01A	75 years, male, white, stage:i, alive, 1155 days	809.2
TCGA-DC-4749-01A	57 years, male, white, stage:i, alive, 762 days	744.0
TCGA-DC-4745-01A	49 years, female, white, stage:iiib, alive, 639 days	743.7
TCGA-F5-6812-01A	67 years, male, white, stage:iia, alive, 1110 days	740.5
TCGA-EI-6512-01A	64 years, female, white, stage:iiib, alive, 538 days	738.8
TCGA-EI-6510-01A	77 years, female, white, alive, 556 days	728.7
TCGA-AG-3898-01A	61 years, male, stage:iia, alive, 1461 days	724.3
TCGA-EI-7004-01A	37 years, female, white, alive, 257 days	722.1
TCGA-F5-6814-01A	57 years, male, white, stage:iia, alive, 1131 days	712.7
TCGA-AG-3582-01A	75 years, male, stage:iv, dead, 1096 days	710.2
TCGA-AH-6903-01A	46 years, male, white, stage:iiib, alive, 592 days	701.4
TCGA-G5-6233-01A	74 years, male, white, dead, 556 days	701.3
TCGA-CI-6621-01A	63 years, male, white, stage:iiib, alive, 419 days	698.6
TCGA-EI-6884-01A	71 years, male, white, stage:iiia, alive, 328 days	693.0
TCGA-AG-3593-01A	72 years, female, stage:iia, alive, 1035 days	669.3
TCGA-F5-6864-01A	74 years, female, white, stage:iiib, alive, 379 days	668.1
TCGA-AF-6655-01A	66 years, male, white, stage:iiia, alive, 609 days	659.5
TCGA-AG-4008-01A	63 years, male, stage:iia, alive, 518 days	658.0
TCGA-CL-4957-01A	79 years, female, dead, 425 days	655.5
TCGA-CI-6622-01A	74 years, male, white, stage:iib, alive, 1362 days	649.4
TCGA-AG-3901-01A	67 years, female, stage:iiib, alive, 761 days	648.9
TCGA-AG-3609-01A	65 years, female, stage:iiic, alive, 608 days	634.7
TCGA-AG-3581-01A	63 years, male, stage:i, alive, 215 days	618.5
TCGA-AH-6544-01A	60 years, male, white, alive, 1173 days	614.6
TCGA-F5-6702-01A	71 years, male, white, stage:iva, alive, 869 days	612.4
TCGA-AG-3887-01A	68 years, male, stage:iia, alive, 1124 days	612.1
TCGA-AG-A00C-01A	49 years, female, stage:iiib, alive, 183 days	607.7
TCGA-F5-6813-01A	70 years, male, white, stage:iiic, dead, 598 days	606.1
TCGA-AF-6136-01A	72 years, female, white, stage:iiib, alive, 741 days	606.0
TCGA-AF-3911-01A	48 years, male, white, stage:iiic, alive, 1148 days	591.3
TCGA-EF-5831-01A	72 years, male, white, stage:iia, alive, 127 days	585.4
TCGA-EI-6882-01A	59 years, male, white, stage:iia, alive, 262 days	582.8
TCGA-AG-A036-01A	71 years, male, stage:iii, alive, 3562 days	581.3
TCGA-AG-3893-01A	74 years, male, stage:iiib, alive, 1065 days	577.8
TCGA-AG-3591-01A	66 years, female, stage:iia, alive, 1035 days	576.9
TCGA-AG-3583-01A	66 years, male, stage:iv, dead, 610 days	575.1
TCGA-DC-6681-01A	70 years, female, white, stage:iva, alive, 790 days	564.8
TCGA-EI-6513-01A	59 years, male, white, stage:iiib, alive, 497 days	559.3
TCGA-AG-3605-01A	85 years, female, stage:iv, alive, 30 days	555.3
TCGA-EI-6881-01A	60 years, male, white, stage:iiia, alive, 499 days	554.6
TCGA-F5-6861-01A	60 years, female, white, stage:iia, alive, 1160 days	537.5
TCGA-EI-6507-01A	60 years, male, white, stage:iia, alive, 607 days	536.1
TCGA-G5-6641-01A	67 years, male, white, stage:iiia, alive, 804 days	533.2
TCGA-DC-6682-01A	57 years, male, white, stage:iia, alive, 762 days	533.2
TCGA-AG-3890-01A	62 years, male, stage:i, alive, 518 days	528.9
TCGA-EI-6917-01A	33 years, male, white, stage:iiia, alive, 531 days	528.0
TCGA-AG-3587-01A	65 years, male, stage:i, alive, 1400 days	523.2
TCGA-AG-A008-01A	50 years, female, stage:i, alive, 424 days	516.2
TCGA-EI-6514-01A	59 years, female, white, stage:iia, alive, 496 days	513.1
TCGA-CI-6619-01B	41 years, male, white, stage:iv, alive, 184 days	508.1
TCGA-AG-3725-01A	90 years, female, stage:iii, alive, 638 days	499.4
TCGA-DC-5869-01A	62 years, female, black or african american, stage:iiib, alive, 943 days	498.4
TCGA-AG-4007-01A	87 years, male, stage:iv, alive, 31 days	488.2
TCGA-AG-3592-01A	68 years, male, stage:iia, alive, 1035 days	476.8
TCGA-AG-3883-01A	69 years, male, stage:i, alive, 31 days	473.3
TCGA-AG-3896-01A	85 years, female, stage:i, alive, 31 days	470.9
TCGA-AG-4001-01A	74 years, female, stage:iia, alive, 1096 days	468.8
TCGA-DC-6683-01A	43 years, male, white, stage:iiib, alive, 762 days	467.8
TCGA-AG-A020-01A	57 years, female, stage:iii, alive, 31 days	467.4
TCGA-AG-A01J-01A	59 years, female, stage:iia, alive, 31 days	458.9
TCGA-F5-6571-01A	62 years, female, white, stage:iia, alive, 1288 days	450.6
TCGA-AG-4021-01A	84 years, female, stage:iv, dead, 121 days	448.5
TCGA-AG-3894-01A	65 years, male, stage:iia, alive, 426 days	439.3
TCGA-AG-A032-01A	68 years, male, stage:iiib, alive, 1157 days	438.0
TCGA-AG-A011-01A	80 years, male, stage:iia, alive, 1126 days	435.9
TCGA-AH-6643-01A	50 years, male, white, stage:iiic, dead, 1314 days	429.4
TCGA-EI-6508-01A	48 years, female, white, stage:iiib, alive, 636 days	426.8
TCGA-AF-2692-01A	54 years, female, white, stage:iia, alive, 412 days	425.4
TCGA-AF-A56K-01A	56 years, male, black or african american, stage:iia, alive, 2635 days	422.8
TCGA-AG-A023-01A	62 years, female, stage:iv, dead, 1581 days	417.7
TCGA-AH-6644-01A	73 years, male, white, alive, 838 days	414.3
TCGA-AF-6672-01A	43 years, male, white, stage:iv, alive, 748 days	410.5
TCGA-CI-6623-01B	44 years, male, white, stage:i, alive, 1443 days	407.8
TCGA-DC-6157-01A	48 years, male, black or african american, stage:i, alive, 1581 days	405.3
TCGA-DY-A1DF-01A	73 years, female, white, stage:iiic, dead, 734 days	404.9
TCGA-DC-6154-01A	57 years, female, white, stage:iva, alive, 365 days	403.2
TCGA-AG-3732-01A	78 years, female, stage:i, alive, 1003 days	402.3
TCGA-EI-7002-01A	58 years, male, white, stage:iv, alive, 364 days	397.8
TCGA-AG-A02X-01A	77 years, male, stage:i, alive, 1247 days	389.1
TCGA-AH-6549-01A	66 years, male, white, alive, 532 days	387.0
TCGA-AG-A015-01A	64 years, female, stage:i, alive, 1096 days	386.6
TCGA-AG-3600-01A	62 years, male, stage:iiic, alive, 184 days	386.4
TCGA-AG-A02G-01A	66 years, male, stage:iv, dead, 1185 days	383.8
TCGA-DY-A1DC-01A	72 years, female, white, stage:iia, dead, 1258 days	380.8
TCGA-AG-3882-01A	66 years, female, stage:i, alive, 608 days	376.8
TCGA-AG-A025-01A	62 years, female, stage:i, alive, 1520 days	376.1
TCGA-AG-3878-01A	64 years, male, stage:i, alive, 30 days	375.0
TCGA-EF-5830-01A	54 years, male, white, stage:iib, alive, 106 days	373.4
TCGA-EI-6509-01A	53 years, male, white, stage:iiic, alive, 517 days	363.1
TCGA-AG-3909-01A	69 years, female, stage:iiib, alive, 608 days	362.6
TCGA-AG-3728-01A	73 years, male, stage:iiib, alive, 912 days	361.0
TCGA-CL-5918-01A	90 years, female, white, stage:iia, alive, 218 days	359.3
TCGA-AF-A56N-01A	47 years, female, black or african american, stage:iia, alive, 360 days	358.4
TCGA-AG-3584-01A	60 years, male, stage:iv, dead, 730 days	358.0
TCGA-AG-A02N-01A	67 years, male, stage:ii, alive, 1885 days	352.2
TCGA-AG-3578-01A	76 years, female, stage:iia, alive, 974 days	349.7
TCGA-AF-5654-01A	73 years, female, white, stage:i, dead, 512 days	344.4
TCGA-AG-3574-01A	89 years, female, stage:ii, dead, 1096 days	336.8
TCGA-DY-A1DG-01A	75 years, male, white, stage:iva, dead, 1566 days	335.3
TCGA-AH-6897-01A	48 years, male, white, stage:i, alive, 804 days	331.2
TCGA-AG-4005-01A	64 years, male, stage:iv, alive, 427 days	330.5
TCGA-AG-3742-01A	85 years, female, stage:i, alive, 30 days	330.2
TCGA-AG-3881-01A	83 years, female, stage:iia, alive, 579 days	318.1
TCGA-AG-3612-01A	55 years, female, stage:iiib, alive, 608 days	313.9
TCGA-CI-6620-01A	41 years, female, white, stage:iva, alive, 1009 days	313.8
TCGA-DY-A0XA-01A	57 years, female, white, stage:iia, alive, 3846 days	297.3
TCGA-BM-6198-01A	73 years, male, white, stage:iiib, alive, 646 days	286.7
TCGA-CL-5917-01A	71 years, female, white, stage:iiic, alive, 2376 days	284.3
TCGA-EI-6885-01A	57 years, female, white, stage:iv, alive, 415 days	282.9
TCGA-AG-A00Y-01A	68 years, male, stage:iia, alive, 700 days	279.6
TCGA-AF-A56L-01A	48 years, female, black or african american, stage:iiic, alive, 2007 days	277.0
TCGA-AG-A014-01A	86 years, male, stage:i, alive, 485 days	273.4
TCGA-AG-3885-01A	71 years, female, stage:iiib, alive, 546 days	272.5
TCGA-AG-A00H-01A	75 years, male, stage:iia, alive, 790 days	263.6
TCGA-F5-6863-01A	71 years, female, white, stage:iiib, dead, 361 days	252.7
TCGA-AF-3913-01A	60 years, male, black or african american, stage:iv, dead, 316 days	232.1
TCGA-AG-A01N-01A	68 years, female, stage:iv, alive, 943 days	226.2
TCGA-G5-6572-01A	56 years, male, white, dead, 1432 days	216.2
TCGA-AG-3999-01A	61 years, female, stage:iiic, alive, 853 days	208.4
TCGA-AG-A016-01A	55 years, male, stage:iv, alive, 276 days	177.4
TCGA-DY-A1H8-01A	77 years, female, white, stage:iiia, dead, 992 days	172.0
TCGA-AG-A026-01A	66 years, male, stage:ii, dead, 59 days	168.7
TCGA-AG-A002-01A	35 years, male, stage:i, alive, 638 days	167.7
TCGA-DY-A1DD-01A	77 years, female, white, stage:iiib, dead, 1741 days	151.9
TCGA-AG-3726-01A	63 years, female, stage:i, alive, 243 days	118.3
TCGA-EI-6883-01A	63 years, male, white, stage:iic, alive, 350 days	114.9
TCGA-DC-6155-01A	31 years, female, white, stage:iiia, alive, 425 days	93.5
TCGA-AG-3727-01A	78 years, female, stage:iii, alive, 30 days	64.2
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