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The primary data page shows the detailed antibody staining in 76 different cell types for each analyzed antibody. In addition, for each cell type, a knowledge-based annotated protein expression score based on all analyzed antibodies is displayed furthest to the right. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
The tissues and cell types can be ordered by organ, cell type or alphabetically. If ordered by organ, the tissues are presented in groups according to functional features. If ordered by cell type, the cells are presented in groups related to origin.
This score describes the level of antibody staining observed in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is based on the staining intensity and fraction of stained cells. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
This score describes a knowledge-based best estimate of the protein expression in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is a result of stringent evaluation of immunohistochemical staining pattern, RNA data from internal and external sources and available protein/gene characterization data. More information can be found in Assays & Annotation.
Summarizing texts describe the staining pattern for each antibody based on staining intensity, fraction of stained cells and subcellular localization. More information can be found in Assays & Annotation.
HPA042097
Fraction of glial cells and neuronal cells along with smooth muscle cells and testis displayed moderate to strong cytoplasmic and nuclear staining. Adrenal cortical cells, hematopoietic cells, renal tubular cells, squamous epithelia and exocrine pancreas showed moderate to strong cytoplasmic staining. Remaining normal tissues were negative.
CAB005044
Strong cytoplasmic staining was observed in smooth muscle for example in duodenum. Moderate to strong cytoplasmic and nuclear staining was observed in adrenal cortex, glial and myoepithelial cells as well as a subset of cells in lymphoid tissues. Remaining tissues were in general weakly stained or negative.
CAB009803
Most of the normal cells showed weak to moderate cytoplasmic immunoreactivity. Glial cells displayed strong nuclear and cytoplasmic positivity. Cells in lymphoid tissues and the female reproductive system were negative.