Expression of COL3A1 in pancreatic cancer

PANCREATIC CANCER - Interactive survival scatter plotⁱ

The Survival Scatter plot shows the clinical status (i.e. dead or alive) for all individuals in the patient cohort, based on the same data that underlies the corresponding Kaplan-Meier plots. Patients that are alive at last time for follow-up are shown in blue and patients who have died during the study are shown in red.

The x-axis shows the expression levels (FPKM) of the investigated gene in the tumor tissue at the time of diagnosis. The y-axis shows the follow-up time after diagnosis (years). Both axes are complimented with kernel density curves demonstrating the data density over the axes. The top density plot shows the expression levels (FPKM) distribution among dead (red) and alive patients (blue). The right density plot shows the data density of the survived years of dead patients with high and low expression levels respectively, stratified using the cutoff indicated by the vertical dashed line through the Survival Scatter plot. This cutoff is automatically defined based on the FPKM cutoff that minimizes the p-score. The cutoff can be changed by dragging the vertical line or by entering a cutoff value in the square labeled "Current cut-off".

Under the Survival Scatter plot the p-score landscape (black curve; left axis) is shown together with dead median separation (red curve; right axis). Dead median separation is the difference in median mRNA expression between patients who have died with high and low expression, respectively. It is calculated as follows: median FPKM expression of dead patients with high expression - median FPKM expression of dead patients with low expression. This is intended to aid the user in visually exploring custom cutoffs and the associated p-scores and dead median separation.

Individual patient data is displayed and can be filtered by clicking on one or more of the category buttons on the top of the page. Categories describing expression level and patient information include: high, low, alive, dead, female, male and tumor stages. The scale of the x-axis can be toggled between linear and log-scale by clicking on the "x log" button. Mouse-over function shows TCGA ID, patient information and mRNA expression (FPKM) for each patient.

& Survival analysisⁱ

COL3A1 is not prognostic in pancreatic cancer

Stage:

Survival analysis

Current cut offⁱ:
Best expression cut offⁱ: 329.03
Median expressionⁱ: N/A
Median follow up timeⁱ: N/A
P scoreⁱ N/A
5-year survival highⁱ N/A
5-year survival lowⁱ N/A

TCGA RNA samplesⁱ

Average FPKM

887.7

Number of samples

176

Samples

Sample	Description	FPKM
TCGA-IB-7893-01A	64 years, male, white, stage:iia, dead, 117 days	4454.2
TCGA-HZ-7925-01A	66 years, male, white, stage:iib, dead, 614 days	3922.0
TCGA-IB-AAUV-01A	49 years, male, white, stage:iib, alive, 404 days	3657.6
TCGA-YH-A8SY-01A	73 years, female, white, alive, 388 days	3457.0
TCGA-HZ-8005-01A	81 years, male, white, stage:iib, dead, 120 days	3381.5
TCGA-FB-AAPS-01A	62 years, female, white, stage:iib, alive, 228 days	3136.9
TCGA-IB-7890-01A	73 years, male, stage:ib, dead, 598 days	2573.7
TCGA-3A-A9IC-01A	61 years, female, white, stage:iib, dead, 738 days	2479.6
TCGA-HZ-A77Q-01A	55 years, female, white, stage:iib, alive, 33 days	2247.0
TCGA-HV-AA8V-01A	50 years, male, asian, stage:iib, alive, 920 days	2206.2
TCGA-HZ-7922-01A	61 years, female, white, stage:iib, alive, 4 days	2179.4
TCGA-IB-AAUS-01A	84 years, female, white, stage:iib, alive, 225 days	2083.9
TCGA-XD-AAUG-01A	66 years, female, white, stage:iv, alive, 420 days	2081.2
TCGA-HZ-8001-01A	69 years, male, white, stage:iii, alive, 706 days	1840.9
TCGA-IB-A5SS-01A	64 years, female, white, stage:iib, dead, 460 days	1796.1
TCGA-IB-7885-01A	78 years, female, white, stage:iib, alive, 1257 days	1727.1
TCGA-IB-AAUP-01A	68 years, male, white, stage:iib, alive, 431 days	1684.5
TCGA-IB-A5SQ-01A	56 years, female, white, stage:ib, dead, 219 days	1676.0
TCGA-IB-7646-01A	60 years, male, white, stage:iib, dead, 145 days	1652.6
TCGA-3A-A9I7-01A	45 years, male, black or african american, stage:iib, alive, 1323 days	1592.7
TCGA-US-A774-01A	76 years, female, white, stage:iib, dead, 695 days	1587.5
TCGA-YB-A89D-01A	59 years, male, white, stage:iib, alive, 350 days	1551.9
TCGA-2J-AAB8-01A	71 years, male, white, stage:iib, alive, 80 days	1490.3
TCGA-F2-A44H-01A	65 years, male, white, stage:iia, alive, 586 days	1468.7
TCGA-HZ-8002-01A	61 years, male, white, stage:iib, dead, 366 days	1391.0
TCGA-2J-AABO-01A	43 years, male, white, stage:iib, alive, 440 days	1371.5
TCGA-IB-7645-01A	44 years, female, stage:iib, dead, 1502 days	1339.8
TCGA-IB-A5ST-01A	64 years, female, white, stage:iib, alive, 635 days	1328.3
TCGA-IB-7886-01A	80 years, male, white, stage:iib, dead, 123 days	1328.2
TCGA-2J-AABP-01A	58 years, female, white, stage:iib, alive, 463 days	1326.4
TCGA-XD-AAUL-01A	56 years, male, white, stage:iia, alive, 498 days	1309.7
TCGA-IB-7888-01A	66 years, female, black or african american, stage:iia, dead, 1332 days	1306.3
TCGA-F2-7276-01A	64 years, male, white, stage:iib, dead, 216 days	1275.8
TCGA-XN-A8T5-01A	53 years, female, white, stage:ib, alive, 720 days	1267.4
TCGA-IB-7887-01A	62 years, female, white, stage:iib, dead, 110 days	1255.1
TCGA-IB-7654-01A	80 years, male, white, stage:iib, dead, 476 days	1252.1
TCGA-US-A77E-01A	73 years, male, white, stage:iib, dead, 430 days	1243.8
TCGA-RB-A7B8-01A	81 years, female, white, stage:iib, dead, 466 days	1241.6
TCGA-RL-AAAS-01A	60 years, female, white, stage:ib, alive, 9 days	1229.8
TCGA-FB-A7DR-01A	48 years, male, asian, stage:iia, dead, 353 days	1195.1
TCGA-2J-AABE-01A	73 years, male, white, stage:iia, alive, 676 days	1193.4
TCGA-F2-7273-01A	54 years, male, black or african american, stage:iib, dead, 592 days	1185.1
TCGA-3A-A9IB-01A	69 years, female, white, stage:iib, dead, 224 days	1184.5
TCGA-IB-A5SO-01A	71 years, male, white, stage:iib, dead, 365 days	1142.3
TCGA-2J-AAB6-01A	75 years, male, white, stage:iia, dead, 293 days	1120.2
TCGA-3A-A9IX-01A	40 years, male, white, stage:ia, alive, 1037 days	1116.7
TCGA-HZ-7918-01A	72 years, male, white, stage:iib, alive, 969 days	1101.9
TCGA-XN-A8T3-01A	67 years, male, white, stage:ib, alive, 951 days	1096.8
TCGA-IB-7644-01A	65 years, female, white, stage:iv, dead, 394 days	1093.8
TCGA-PZ-A5RE-01A	44 years, female, white, stage:iib, dead, 470 days	1069.4
TCGA-2J-AABU-01A	56 years, male, white, stage:iib, dead, 277 days	1065.7
TCGA-3E-AAAZ-01A	71 years, male, white, stage:iia, dead, 2182 days	1053.1
TCGA-2J-AABA-01A	55 years, male, white, stage:iib, dead, 607 days	1035.3
TCGA-HZ-A4BH-01A	75 years, male, white, stage:iib, alive, 194 days	1023.1
TCGA-3A-A9J0-01A	75 years, male, white, stage:iib, alive, 743 days	1023.0
TCGA-M8-A5N4-01A	48 years, female, stage:iia, alive, 584 days	1018.1
TCGA-F2-A8YN-01A	76 years, male, white, stage:iia, alive, 517 days	1017.9
TCGA-IB-AAUQ-01A	50 years, male, white, stage:iib, dead, 183 days	1014.9
TCGA-3A-A9IZ-01A	47 years, male, white, stage:iib, dead, 308 days	1013.6
TCGA-IB-7891-01A	49 years, female, white, stage:iib, dead, 913 days	1011.6
TCGA-H6-A45N-01A	88 years, female, white, stage:iib, dead, 421 days	1002.0
TCGA-F2-6879-01A	57 years, male, white, stage:iib, dead, 334 days	988.0
TCGA-IB-7651-01A	64 years, female, white, stage:iib, dead, 603 days	971.2
TCGA-H6-8124-01A	56 years, female, white, stage:iib, alive, 392 days	968.4
TCGA-IB-AAUR-01A	67 years, male, white, stage:iib, alive, 338 days	959.9
TCGA-F2-A44G-01A	79 years, female, white, stage:iib, dead, 233 days	958.7
TCGA-HZ-A77P-01A	77 years, male, white, stage:iib, alive, 330 days	956.8
TCGA-HV-A5A5-01A	61 years, female, asian, stage:iib, alive, 289 days	945.8
TCGA-HV-A5A6-01A	65 years, female, asian, stage:iib, dead, 2036 days	937.1
TCGA-HZ-8636-01A	58 years, female, white, stage:iv, dead, 545 days	936.1
TCGA-FB-A545-01A	72 years, female, white, stage:iib, dead, 732 days	930.5
TCGA-FB-A4P5-01A	69 years, female, white, stage:iib, dead, 179 days	929.8
TCGA-HZ-8317-01A	69 years, female, white, stage:iib, dead, 378 days	927.3
TCGA-IB-7652-01A	49 years, female, asian, stage:iib, alive, 1116 days	927.1
TCGA-HZ-8315-01A	54 years, female, white, stage:iia, dead, 299 days	923.6
TCGA-HZ-7919-01A	52 years, female, white, stage:iib, dead, 593 days	916.5
TCGA-IB-AAUT-01A	65 years, male, white, stage:iib, alive, 287 days	903.3
TCGA-IB-7649-01A	73 years, female, stage:iib, dead, 467 days	885.4
TCGA-HV-A5A4-01A	72 years, female, asian, stage:iia, alive, 232 days	873.4
TCGA-L1-A7W4-01A	48 years, female, white, stage:iib, dead, 278 days	852.7
TCGA-IB-7897-01A	54 years, female, white, stage:iib, dead, 486 days	851.0
TCGA-3A-A9IU-01A	65 years, male, white, stage:iib, dead, 458 days	839.4
TCGA-HZ-A49H-01A	68 years, female, white, stage:iib, alive, 491 days	821.3
TCGA-FB-A4P6-01A	54 years, male, white, stage:iib, alive, 767 days	798.2
TCGA-IB-8127-01A	59 years, male, white, stage:iib, alive, 522 days	795.5
TCGA-US-A77J-01A	81 years, female, white, stage:iib, dead, 568 days	789.5
TCGA-XD-AAUH-01A	57 years, female, white, stage:iib, alive, 395 days	773.7
TCGA-HZ-8637-01A	76 years, female, white, stage:iib, dead, 517 days	771.6
TCGA-S4-A8RP-01A	77 years, female, white, stage:iib, dead, 702 days	760.6
TCGA-HZ-8519-01A	73 years, male, white, stage:ia, alive, 454 days	733.4
TCGA-HZ-7923-01A	65 years, male, white, stage:iia, alive, 314 days	732.7
TCGA-2J-AABR-01A	60 years, female, white, stage:iia, alive, 438 days	725.9
TCGA-2J-AAB9-01A	71 years, female, white, stage:iib, dead, 627 days	689.6
TCGA-H8-A6C1-01A	53 years, male, white, stage:iia, alive, 671 days	688.4
TCGA-2J-AABF-01A	73 years, male, white, stage:iib, dead, 691 days	687.9
TCGA-HZ-7926-01A	57 years, male, black or african american, stage:iib, dead, 518 days	677.3
TCGA-RB-AA9M-01A	43 years, male, white, stage:iib, alive, 286 days	668.8
TCGA-HZ-8003-01A	65 years, female, white, stage:iib, dead, 596 days	641.0
TCGA-HZ-A4BK-01A	72 years, male, white, stage:iib, alive, 657 days	639.9
TCGA-Q3-A5QY-01A	58 years, male, white, stage:iib, alive, 416 days	639.4
TCGA-HZ-A49G-01A	58 years, female, white, stage:iib, alive, 660 days	637.8
TCGA-IB-AAUN-01A	74 years, female, white, stage:ib, dead, 144 days	636.7
TCGA-2J-AABI-01A	55 years, female, white, stage:iia, alive, 969 days	636.1
TCGA-2L-AAQA-01A	76 years, male, white, stage:iib, dead, 143 days	634.9
TCGA-HZ-7920-01A	71 years, male, white, stage:ib, dead, 236 days	628.5
TCGA-OE-A75W-01A	75 years, male, white, stage:iia, dead, 267 days	608.0
TCGA-FB-AAQ3-01A	65 years, female, white, stage:iib, dead, 31 days	603.0
TCGA-3E-AAAY-01A	67 years, male, white, stage:iib, alive, 2285 days	590.2
TCGA-2J-AABT-01A	72 years, female, white, stage:iib, alive, 319 days	586.7
TCGA-FB-A5VM-01A	74 years, male, white, stage:ib, dead, 498 days	576.3
TCGA-FB-AAPZ-01A	54 years, male, white, stage:iib, alive, 716 days	567.5
TCGA-XD-AAUI-01A	50 years, female, white, stage:iib, dead, 366 days	566.2
TCGA-HZ-A49I-01A	77 years, male, white, stage:iib, dead, 308 days	550.8
TCGA-HV-A5A3-01A	50 years, male, asian, stage:iia, dead, 128 days	539.3
TCGA-2L-AAQE-01A	56 years, male, white, stage:iib, dead, 684 days	521.9
TCGA-FB-AAPQ-01A	65 years, male, white, stage:iib, dead, 1130 days	507.0
TCGA-2J-AABH-01A	61 years, male, white, stage:iia, alive, 1287 days	471.9
TCGA-2L-AAQL-01A	82 years, male, white, stage:iib, dead, 292 days	463.9
TCGA-HZ-A77O-01A	77 years, female, white, stage:iib, dead, 160 days	445.4
TCGA-3A-A9I5-01A	58 years, male, white, alive, 1794 days	432.0
TCGA-IB-AAUU-01A	35 years, male, white, stage:iib, alive, 245 days	425.2
TCGA-2J-AAB1-01A	65 years, male, white, stage:iib, dead, 66 days	403.6
TCGA-2J-AAB4-01A	48 years, male, white, stage:iib, alive, 729 days	401.3
TCGA-FB-AAPY-01A	71 years, male, white, stage:iib, dead, 1059 days	396.7
TCGA-S4-A8RO-01A	75 years, female, white, stage:iib, alive, 525 days	388.8
TCGA-2L-AAQJ-01A	49 years, female, white, stage:iii, dead, 394 days	388.6
TCGA-IB-7889-01A	86 years, female, white, stage:iib, dead, 481 days	388.4
TCGA-F2-A7TX-01A	77 years, male, white, stage:iib, dead, 95 days	384.3
TCGA-HZ-8638-01A	84 years, female, white, stage:ia, dead, 151 days	384.0
TCGA-IB-A7M4-01A	81 years, male, white, stage:iib, alive, 483 days	375.1
TCGA-3A-A9IV-01A	59 years, female, white, stage:ib, alive, 1103 days	369.6
TCGA-LB-A9Q5-01A	63 years, female, white, stage:iib, dead, 313 days	364.8
TCGA-IB-A7LX-01A	57 years, male, white, stage:iib, dead, 250 days	363.8
TCGA-2L-AAQI-01A	66 years, male, white, stage:iib, dead, 103 days	363.5
TCGA-HZ-7289-01A	77 years, male, white, stage:iib, dead, 661 days	358.3
TCGA-HV-A7OL-01A	70 years, male, asian, stage:iia, alive, 252 days	353.5
TCGA-3A-A9IH-01A	66 years, female, white, stage:ia, alive, 1021 days	348.9
TCGA-IB-AAUW-01A	63 years, female, white, stage:iib, dead, 230 days	339.8
TCGA-FB-AAQ1-01A	49 years, male, white, stage:iib, dead, 123 days	338.0
TCGA-HV-AA8X-01A	75 years, female, asian, stage:iib, dead, 532 days	333.8
TCGA-IB-AAUO-01A	64 years, female, white, stage:iib, dead, 239 days	324.2
TCGA-IB-A6UF-01A	63 years, male, white, stage:iib, alive, 666 days	323.3
TCGA-3A-A9I9-01A	67 years, male, white, stage:iia, dead, 634 days	312.9
TCGA-HZ-7924-01A	60 years, female, white, stage:iia, alive, 840 days	312.3
TCGA-FB-AAQ6-01A	85 years, male, white, stage:ia, dead, 244 days	307.1
TCGA-LB-A8F3-01A	64 years, female, black or african american, stage:iia, alive, 379 days	282.5
TCGA-Q3-AA2A-01A	64 years, female, white, stage:ib, alive, 95 days	278.2
TCGA-FB-AAQ0-01A	68 years, male, white, stage:iia, dead, 473 days	272.8
TCGA-FB-AAQ2-01A	81 years, female, white, stage:iib, dead, 153 days	263.1
TCGA-IB-8126-01A	80 years, female, white, stage:iii, alive, 462 days	246.6
TCGA-IB-A6UG-01A	65 years, male, white, stage:iib, dead, 41 days	243.5
TCGA-S4-A8RM-01A	67 years, male, white, stage:iib, alive, 737 days	241.3
TCGA-HZ-A9TJ-01A	70 years, male, white, stage:iv, alive, 603 days	235.0
TCGA-HZ-A8P1-01A	81 years, male, white, stage:ib, alive, 7 days	224.6
TCGA-LB-A7SX-01A	74 years, female, black or african american, stage:iib, dead, 393 days	221.8
TCGA-Z5-AAPL-01A	74 years, female, white, stage:iia, alive, 467 days	207.0
TCGA-IB-AAUM-01A	76 years, male, white, stage:iib, alive, 8 days	196.8
TCGA-FB-A78T-01A	71 years, female, white, stage:iib, dead, 375 days	186.3
TCGA-FB-AAPU-01A	41 years, female, asian, stage:iia, dead, 381 days	184.0
TCGA-3A-A9IN-01A	62 years, female, white, stage:ib, alive, 2084 days	145.8
TCGA-IB-A5SP-01A	77 years, male, white, stage:iia, alive, 482 days	142.6
TCGA-2L-AAQM-01A	52 years, male, white, stage:iib, alive, 1383 days	112.3
TCGA-3A-A9IL-01A	39 years, female, white, stage:i, alive, 2741 days	104.3
TCGA-2J-AABK-01A	71 years, male, white, stage:iib, alive, 484 days	100.7
TCGA-US-A779-01A	54 years, female, white, stage:iib, dead, 511 days	95.5
TCGA-YY-A8LH-01A	61 years, female, white, stage:iib, alive, 2016 days	93.2
TCGA-US-A77G-01A	64 years, male, white, stage:iib, dead, 12 days	79.0
TCGA-2J-AABV-01A	74 years, male, white, stage:iib, dead, 652 days	56.4
TCGA-FB-AAPP-01A	71 years, male, white, stage:iib, dead, 485 days	52.2
TCGA-US-A776-01A	61 years, male, white, stage:iia, alive, 1216 days	47.7
TCGA-3A-A9IO-01A	56 years, male, white, alive, 1942 days	37.1
TCGA-3A-A9IR-01A	64 years, female, white, stage:ib, alive, 1542 days	17.6
TCGA-F2-6880-01A	70 years, male, white, stage:iib, alive, 289 days	16.2
TCGA-3A-A9IS-01A	67 years, male, white, stage:ib, alive, 998 days	13.5
TCGA-3A-A9IJ-01A	65 years, male, white, stage:ib, alive, 1854 days	6.6
TCGA-HV-A7OP-01A	72 years, male, asian, stage:iib, alive, 978 days	5.0
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PANCREATIC CANCER - Protein expressionⁱ A mouse-over function shows sample information and annotation data. Click on an image to view it in a full screen mode. Samples can be filtered based on level of antibody staining by selecting one or several of the following categories: high, medium, low and not detected. The assay and annotation is described here. Note that samples used for immunohistochemistry by the Human Protein Atlas do not correspond to samples in the TCGA dataset.

Antibody stainingⁱ Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high. This score is based on the staining intensity and fraction of stained cells. Read more	Antibody HPA007583	Antibody CAB016766	Antibody CAB059993
Staining
High
Medium
Low
Not detected
Intensity
Strong
Moderate
Weak
Negative
Quantity
>75%
75%-25%
<25%
None
Location
Nuclear
Cytoplasmic/membranous
Cytoplasmic/membranous,nuclear
None
Click images for details