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The primary data page shows the detailed antibody staining in 76 different cell types for each analyzed antibody. In addition, for each cell type, a knowledge-based annotated protein expression score based on all analyzed antibodies is displayed furthest to the right. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
The tissues and cell types can be ordered by organ, cell type or alphabetically. If ordered by organ, the tissues are presented in groups according to functional features. If ordered by cell type, the cells are presented in groups related to origin.
This score describes the level of antibody staining observed in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is based on the staining intensity and fraction of stained cells. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
This score describes a knowledge-based best estimate of the protein expression in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is a result of stringent evaluation of immunohistochemical staining pattern, RNA data from internal and external sources and available protein/gene characterization data. More information can be found in Assays & Annotation.
Summarizing texts describe the staining pattern for each antibody based on staining intensity, fraction of stained cells and subcellular localization. More information can be found in Assays & Annotation.
HPA037949
Normal tissues displayed moderate to strong cytoplasmic positivity in granular pattern. Cerebellum, hippocampus, bile duct cells, pneumocytes, smooth muscle cells and adipocytes were weakly stained or negative.
HPA037950
Most normal tissues displayed moderate cytoplasmic positivity, often granular. Superficial layers in squamous epithelia, Paneth cells in the intestine, exocrine pancreas, renal tubules and Purkinje cells showed strong staining. Alveolar cells, bile ducts, glial cells and spleen were negative.
HPA066098
Most normal tissues displayed weak to moderate, granular cytoplasmic positivity. Renal tubules and endometrial glands along with subset of cells in red pulp of spleen and hepatocytes were strongly stained. Bile ducts, renal glomeruli, placental trophoblastic cells and cells of CNS were mostly negative.