Expression of RPL12 in colorectal cancer

RECTUM ADENOCARCINOMA (READ) - Interactive survival scatter plotⁱ

The Survival Scatter plot shows the clinical status (i.e. dead or alive) for all individuals in the patient cohort, based on the same data that underlies the corresponding Kaplan-Meier plots. Patients that are alive at last time for follow-up are shown in blue and patients who have died during the study are shown in red.

The x-axis shows the expression levels (FPKM) of the investigated gene in the tumor tissue at the time of diagnosis. The y-axis shows the follow-up time after diagnosis (years). Both axes are complimented with kernel density curves demonstrating the data density over the axes. The top density plot shows the expression levels (FPKM) distribution among dead (red) and alive patients (blue). The right density plot shows the data density of the survived years of dead patients with high and low expression levels respectively, stratified using the cutoff indicated by the vertical dashed line through the Survival Scatter plot. This cutoff is automatically defined based on the FPKM cutoff that minimizes the p-score. The cutoff can be changed by dragging the vertical line or by entering a cutoff value in the square labeled "Current cut-off".

Under the Survival Scatter plot the p-score landscape (black curve; left axis) is shown together with dead median separation (red curve; right axis). Dead median separation is the difference in median mRNA expression between patients who have died with high and low expression, respectively. It is calculated as follows: median FPKM expression of dead patients with high expression - median FPKM expression of dead patients with low expression. This is intended to aid the user in visually exploring custom cutoffs and the associated p-scores and dead median separation.

Individual patient data is displayed and can be filtered by clicking on one or more of the category buttons on the top of the page. Categories describing expression level and patient information include: high, low, alive, dead, female, male and tumor stages. The scale of the x-axis can be toggled between linear and log-scale by clicking on the "x log" button. Mouse-over function shows TCGA ID, patient information and mRNA expression (FPKM) for each patient.

& Survival analysisⁱ

Stage:

Survival analysis

Current cut offⁱ:
Best expression cut offⁱ: 422.1
Median expressionⁱ: N/A
Median follow up timeⁱ: N/A
P scoreⁱ N/A
5-year survival highⁱ N/A
5-year survival lowⁱ N/A

TCGA RNA samplesⁱ

Average FPKM

443.6

Number of samples

159

Samples

Sample	Description	FPKM
TCGA-DY-A1H8-01A	77 years, female, white, stage:iiia, dead, 992 days	1142.3
TCGA-AG-3605-01A	85 years, female, stage:iv, alive, 30 days	1043.0
TCGA-AG-3574-01A	89 years, female, stage:ii, dead, 1096 days	1029.8
TCGA-DC-4745-01A	49 years, female, white, stage:iiib, alive, 639 days	972.0
TCGA-EI-6883-01A	63 years, male, white, stage:iic, alive, 350 days	909.0
TCGA-AG-3902-01A	61 years, male, stage:iia, alive, 974 days	903.8
TCGA-AG-3598-01A	69 years, male, stage:iia, alive, 1522 days	880.1
TCGA-AG-3894-01A	65 years, male, stage:iia, alive, 426 days	823.3
TCGA-DC-6682-01A	57 years, male, white, stage:iia, alive, 762 days	794.5
TCGA-AG-3896-01A	85 years, female, stage:i, alive, 31 days	755.8
TCGA-AG-3999-01A	61 years, female, stage:iiic, alive, 853 days	722.9
TCGA-DY-A1DG-01A	75 years, male, white, stage:iva, dead, 1566 days	722.0
TCGA-AG-3591-01A	66 years, female, stage:iia, alive, 1035 days	720.7
TCGA-AG-3581-01A	63 years, male, stage:i, alive, 215 days	695.4
TCGA-AG-3887-01A	68 years, male, stage:iia, alive, 1124 days	693.3
TCGA-F5-6861-01A	60 years, female, white, stage:iia, alive, 1160 days	692.8
TCGA-DC-6155-01A	31 years, female, white, stage:iiia, alive, 425 days	690.0
TCGA-EI-6917-01A	33 years, male, white, stage:iiia, alive, 531 days	689.4
TCGA-G5-6233-01A	74 years, male, white, dead, 556 days	661.1
TCGA-DY-A1DD-01A	77 years, female, white, stage:iiib, dead, 1741 days	659.0
TCGA-AG-3609-01A	65 years, female, stage:iiic, alive, 608 days	657.2
TCGA-AF-2691-01A	48 years, female, white, stage:i, alive, 1309 days	651.5
TCGA-AG-3608-01A	79 years, female, stage:iia, alive, 485 days	644.2
TCGA-AG-3611-01A	72 years, male, stage:iia, alive, 424 days	626.5
TCGA-AF-4110-01A	77 years, male, white, stage:iva, alive, 912 days	619.3
TCGA-DY-A0XA-01A	57 years, female, white, stage:iia, alive, 3846 days	615.1
TCGA-AF-5654-01A	73 years, female, white, stage:i, dead, 512 days	595.7
TCGA-EI-6509-01A	53 years, male, white, stage:iiic, alive, 517 days	595.1
TCGA-AG-3580-01A	67 years, male, stage:i, alive, 244 days	589.9
TCGA-AG-A023-01A	62 years, female, stage:iv, dead, 1581 days	584.7
TCGA-BM-6198-01A	73 years, male, white, stage:iiib, alive, 646 days	564.7
TCGA-AG-3583-01A	66 years, male, stage:iv, dead, 610 days	543.3
TCGA-AH-6903-01A	46 years, male, white, stage:iiib, alive, 592 days	538.9
TCGA-EI-6507-01A	60 years, male, white, stage:iia, alive, 607 days	530.9
TCGA-AG-3725-01A	90 years, female, stage:iii, alive, 638 days	529.4
TCGA-AG-A032-01A	68 years, male, stage:iiib, alive, 1157 days	527.7
TCGA-F5-6863-01A	71 years, female, white, stage:iiib, dead, 361 days	522.1
TCGA-AH-6544-01A	60 years, male, white, alive, 1173 days	520.4
TCGA-AH-6644-01A	73 years, male, white, alive, 838 days	520.1
TCGA-EI-7002-01A	58 years, male, white, stage:iv, alive, 364 days	517.9
TCGA-AG-3586-01A	72 years, female, stage:iii, alive, 31 days	517.8
TCGA-AG-3599-01A	70 years, male, stage:i, alive, 366 days	513.5
TCGA-AG-A00C-01A	49 years, female, stage:iiib, alive, 183 days	505.9
TCGA-AG-3909-01A	69 years, female, stage:iiib, alive, 608 days	502.3
TCGA-EI-6510-01A	77 years, female, white, alive, 556 days	502.0
TCGA-AG-4005-01A	64 years, male, stage:iv, alive, 427 days	500.5
TCGA-AF-6672-01A	43 years, male, white, stage:iv, alive, 748 days	500.4
TCGA-AF-3400-01A	54 years, male, white, stage:iia, alive, 1049 days	499.4
TCGA-AG-A02G-01A	66 years, male, stage:iv, dead, 1185 days	496.7
TCGA-DC-5337-01A	69 years, male, white, stage:i, alive, 792 days	493.7
TCGA-AG-A025-01A	62 years, female, stage:i, alive, 1520 days	491.8
TCGA-AG-3881-01A	83 years, female, stage:iia, alive, 579 days	490.4
TCGA-AG-A008-01A	50 years, female, stage:i, alive, 424 days	485.8
TCGA-CL-5918-01A	90 years, female, white, stage:iia, alive, 218 days	477.9
TCGA-G5-6572-01A	56 years, male, white, dead, 1432 days	475.9
TCGA-AH-6643-01A	50 years, male, white, stage:iiic, dead, 1314 days	472.1
TCGA-AG-A02N-01A	67 years, male, stage:ii, alive, 1885 days	468.8
TCGA-DY-A1DF-01A	73 years, female, white, stage:iiic, dead, 734 days	468.3
TCGA-EF-5830-01A	54 years, male, white, stage:iib, alive, 106 days	463.0
TCGA-AG-4007-01A	87 years, male, stage:iv, alive, 31 days	462.7
TCGA-DY-A1DE-01A	56 years, female, white, stage:iia, alive, 3932 days	455.7
TCGA-AG-3892-01A	57 years, female, stage:i, alive, 396 days	451.3
TCGA-DC-6681-01A	70 years, female, white, stage:iva, alive, 790 days	450.3
TCGA-F5-6813-01A	70 years, male, white, stage:iiic, dead, 598 days	449.8
TCGA-G5-6641-01A	67 years, male, white, stage:iiia, alive, 804 days	442.2
TCGA-AG-3584-01A	60 years, male, stage:iv, dead, 730 days	442.1
TCGA-EI-7004-01A	37 years, female, white, alive, 257 days	442.0
TCGA-AG-3898-01A	61 years, male, stage:iia, alive, 1461 days	440.0
TCGA-AG-3612-01A	55 years, female, stage:iiib, alive, 608 days	433.3
TCGA-AG-A020-01A	57 years, female, stage:iii, alive, 31 days	431.5
TCGA-DT-5265-01A	51 years, male, asian, stage:ii, alive, 384 days	431.3
TCGA-AG-3594-01A	77 years, male, stage:iia, dead, 61 days	424.3
TCGA-F5-6814-01A	57 years, male, white, stage:iia, alive, 1131 days	423.1
TCGA-DY-A1DC-01A	72 years, female, white, stage:iia, dead, 1258 days	422.4
TCGA-AG-A015-01A	64 years, female, stage:i, alive, 1096 days	421.8
TCGA-AG-3732-01A	78 years, female, stage:i, alive, 1003 days	421.5
TCGA-EI-6881-01A	60 years, male, white, stage:iiia, alive, 499 days	420.2
TCGA-AG-3600-01A	62 years, male, stage:iiic, alive, 184 days	417.9
TCGA-AG-4022-01A	59 years, female, stage:ii, alive, 1400 days	417.3
TCGA-AG-3742-01A	85 years, female, stage:i, alive, 30 days	408.8
TCGA-AG-3587-01A	65 years, male, stage:i, alive, 1400 days	406.1
TCGA-AG-3885-01A	71 years, female, stage:iiib, alive, 546 days	404.4
TCGA-AG-A016-01A	55 years, male, stage:iv, alive, 276 days	404.4
TCGA-F5-6864-01A	74 years, female, white, stage:iiib, alive, 379 days	403.9
TCGA-AG-3582-01A	75 years, male, stage:iv, dead, 1096 days	399.0
TCGA-AG-A00Y-01A	68 years, male, stage:iia, alive, 700 days	398.3
TCGA-AF-A56L-01A	48 years, female, black or african american, stage:iiic, alive, 2007 days	397.0
TCGA-DC-5869-01A	62 years, female, black or african american, stage:iiib, alive, 943 days	393.4
TCGA-AF-2690-01A	77 years, female, white, stage:iiic, dead, 524 days	392.3
TCGA-AG-4008-01A	63 years, male, stage:iia, alive, 518 days	386.2
TCGA-AG-3890-01A	62 years, male, stage:i, alive, 518 days	385.7
TCGA-CI-6622-01A	74 years, male, white, stage:iib, alive, 1362 days	381.6
TCGA-AF-2693-01A	75 years, male, white, stage:i, alive, 1155 days	381.5
TCGA-F5-6571-01A	62 years, female, white, stage:iia, alive, 1288 days	378.2
TCGA-AG-A036-01A	71 years, male, stage:iii, alive, 3562 days	375.3
TCGA-AG-3878-01A	64 years, male, stage:i, alive, 30 days	375.1
TCGA-CI-6619-01B	41 years, male, white, stage:iv, alive, 184 days	371.2
TCGA-F5-6465-01A	64 years, female, white, stage:iia, alive, 1506 days	368.3
TCGA-EI-6513-01A	59 years, male, white, stage:iiib, alive, 497 days	365.1
TCGA-AG-A02X-01A	77 years, male, stage:i, alive, 1247 days	360.3
TCGA-AG-3882-01A	66 years, female, stage:i, alive, 608 days	355.0
TCGA-AG-3883-01A	69 years, male, stage:i, alive, 31 days	353.2
TCGA-DC-6157-01A	48 years, male, black or african american, stage:i, alive, 1581 days	352.1
TCGA-AG-A01N-01A	68 years, female, stage:iv, alive, 943 days	349.9
TCGA-AF-6136-01A	72 years, female, white, stage:iiib, alive, 741 days	349.5
TCGA-AG-3575-01A	51 years, male, stage:ii, alive, 365 days	348.6
TCGA-DC-6154-01A	57 years, female, white, stage:iva, alive, 365 days	346.8
TCGA-EF-5831-01A	72 years, male, white, stage:iia, alive, 127 days	343.0
TCGA-F5-6811-01A	72 years, female, white, stage:iia, alive, 979 days	342.7
TCGA-AF-3911-01A	48 years, male, white, stage:iiic, alive, 1148 days	340.4
TCGA-AF-6655-01A	66 years, male, white, stage:iiia, alive, 609 days	339.9
TCGA-AG-A00H-01A	75 years, male, stage:iia, alive, 790 days	328.4
TCGA-AG-3728-01A	73 years, male, stage:iiib, alive, 912 days	328.1
TCGA-G5-6235-01A	72 years, male, white, stage:iiib, alive, 1696 days	326.1
TCGA-AG-A014-01A	86 years, male, stage:i, alive, 485 days	324.4
TCGA-EI-6884-01A	71 years, male, white, stage:iiia, alive, 328 days	319.8
TCGA-CL-5917-01A	71 years, female, white, stage:iiic, alive, 2376 days	318.3
TCGA-AG-3593-01A	72 years, female, stage:iia, alive, 1035 days	317.5
TCGA-AF-A56K-01A	56 years, male, black or african american, stage:iia, alive, 2635 days	315.1
TCGA-CI-6621-01A	63 years, male, white, stage:iiib, alive, 419 days	304.8
TCGA-AG-A01J-01A	59 years, female, stage:iia, alive, 31 days	303.7
TCGA-AG-3901-01A	67 years, female, stage:iiib, alive, 761 days	303.2
TCGA-AG-3727-01A	78 years, female, stage:iii, alive, 30 days	299.1
TCGA-F5-6812-01A	67 years, male, white, stage:iia, alive, 1110 days	297.3
TCGA-AF-A56N-01A	47 years, female, black or african american, stage:iia, alive, 360 days	295.2
TCGA-AH-6549-01A	66 years, male, white, alive, 532 days	294.7
TCGA-AF-3913-01A	60 years, male, black or african american, stage:iv, dead, 316 days	293.6
TCGA-AG-3592-01A	68 years, male, stage:iia, alive, 1035 days	291.8
TCGA-AG-4021-01A	84 years, female, stage:iv, dead, 121 days	290.9
TCGA-AG-3893-01A	74 years, male, stage:iiib, alive, 1065 days	290.3
TCGA-AH-6897-01A	48 years, male, white, stage:i, alive, 804 days	285.8
TCGA-AG-3726-01A	63 years, female, stage:i, alive, 243 days	285.7
TCGA-F5-6464-01A	77 years, female, white, stage:iiic, dead, 303 days	281.7
TCGA-EI-6885-01A	57 years, female, white, stage:iv, alive, 415 days	281.1
TCGA-EI-6511-01A	52 years, male, white, stage:iiib, alive, 482 days	281.0
TCGA-AF-2687-01A	57 years, male, white, stage:iiic, alive, 1427 days	275.8
TCGA-CI-6620-01A	41 years, female, white, stage:iva, alive, 1009 days	275.6
TCGA-DC-6683-01A	43 years, male, white, stage:iiib, alive, 762 days	275.5
TCGA-EI-6506-01A	78 years, female, white, stage:iia, alive, 625 days	273.0
TCGA-AG-A026-01A	66 years, male, stage:ii, dead, 59 days	269.1
TCGA-EI-6514-01A	59 years, female, white, stage:iia, alive, 496 days	267.1
TCGA-DC-6160-01A	68 years, male, white, stage:i, alive, 1339 days	263.9
TCGA-AG-A011-01A	80 years, male, stage:iia, alive, 1126 days	256.7
TCGA-EI-6512-01A	64 years, female, white, stage:iiib, alive, 538 days	255.8
TCGA-DC-6156-01A	62 years, male, white, stage:iva, alive, 943 days	250.9
TCGA-AG-3731-01A	65 years, male, stage:iv, alive, 1126 days	250.6
TCGA-AG-3578-01A	76 years, female, stage:iia, alive, 974 days	239.6
TCGA-CI-6623-01B	44 years, male, white, stage:i, alive, 1443 days	238.2
TCGA-CL-4957-01A	79 years, female, dead, 425 days	230.8
TCGA-AG-4001-01A	74 years, female, stage:iia, alive, 1096 days	228.4
TCGA-AF-2692-01A	54 years, female, white, stage:iia, alive, 412 days	227.6
TCGA-EI-6508-01A	48 years, female, white, stage:iiib, alive, 636 days	227.4
TCGA-F5-6702-01A	71 years, male, white, stage:iva, alive, 869 days	218.1
TCGA-DC-4749-01A	57 years, male, white, stage:i, alive, 762 days	208.1
TCGA-AG-A002-01A	35 years, male, stage:i, alive, 638 days	198.0
TCGA-AH-6547-01A	79 years, female, white, dead, 76 days	195.4
TCGA-DC-6158-01A	70 years, male, white, stage:i, dead, 334 days	164.4
TCGA-EI-6882-01A	59 years, male, white, stage:iia, alive, 262 days	158.8
TCGA-CI-6624-01C	53 years, female, white, stage:i, alive, 1466 days	155.1
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