Expression of MT-ND4 in pancreatic cancer

PANCREATIC CANCER - Interactive survival scatter plotⁱ

The Survival Scatter plot shows the clinical status (i.e. dead or alive) for all individuals in the patient cohort, based on the same data that underlies the corresponding Kaplan-Meier plots. Patients that are alive at last time for follow-up are shown in blue and patients who have died during the study are shown in red.

The x-axis shows the expression levels (FPKM) of the investigated gene in the tumor tissue at the time of diagnosis. The y-axis shows the follow-up time after diagnosis (years). Both axes are complimented with kernel density curves demonstrating the data density over the axes. The top density plot shows the expression levels (FPKM) distribution among dead (red) and alive patients (blue). The right density plot shows the data density of the survived years of dead patients with high and low expression levels respectively, stratified using the cutoff indicated by the vertical dashed line through the Survival Scatter plot. This cutoff is automatically defined based on the FPKM cutoff that minimizes the p-score. The cutoff can be changed by dragging the vertical line or by entering a cutoff value in the square labeled "Current cut-off".

Under the Survival Scatter plot the p-score landscape (black curve; left axis) is shown together with dead median separation (red curve; right axis). Dead median separation is the difference in median mRNA expression between patients who have died with high and low expression, respectively. It is calculated as follows: median FPKM expression of dead patients with high expression - median FPKM expression of dead patients with low expression. This is intended to aid the user in visually exploring custom cutoffs and the associated p-scores and dead median separation.

Individual patient data is displayed and can be filtered by clicking on one or more of the category buttons on the top of the page. Categories describing expression level and patient information include: high, low, alive, dead, female, male and tumor stages. The scale of the x-axis can be toggled between linear and log-scale by clicking on the "x log" button. Mouse-over function shows TCGA ID, patient information and mRNA expression (FPKM) for each patient.

& Survival analysisⁱ

MT-ND4 is not prognostic in pancreatic cancer

Stage:

Survival analysis

Current cut offⁱ:
Best expression cut offⁱ: 4634.9
Median expressionⁱ: N/A
Median follow up timeⁱ: N/A
P scoreⁱ N/A
5-year survival highⁱ N/A
5-year survival lowⁱ N/A

TCGA RNA samplesⁱ

Average FPKM

6319.0

Number of samples

176

Samples

Sample	Description	FPKM
TCGA-3A-A9IV-01A	59 years, female, white, stage:ib, alive, 1103 days	18585.5
TCGA-RB-A7B8-01A	81 years, female, white, stage:iib, dead, 466 days	16084.9
TCGA-F2-A44H-01A	65 years, male, white, stage:iia, alive, 586 days	15581.4
TCGA-HZ-A8P1-01A	81 years, male, white, stage:ib, alive, 7 days	14986.9
TCGA-HV-A5A5-01A	61 years, female, asian, stage:iib, alive, 289 days	14485.2
TCGA-LB-A7SX-01A	74 years, female, black or african american, stage:iib, dead, 393 days	13871.6
TCGA-H8-A6C1-01A	53 years, male, white, stage:iia, alive, 671 days	13686.8
TCGA-FB-AAQ1-01A	49 years, male, white, stage:iib, dead, 123 days	13336.5
TCGA-Q3-AA2A-01A	64 years, female, white, stage:ib, alive, 95 days	13019.3
TCGA-2J-AABK-01A	71 years, male, white, stage:iib, alive, 484 days	12607.7
TCGA-FB-AAPY-01A	71 years, male, white, stage:iib, dead, 1059 days	12269.9
TCGA-2J-AABH-01A	61 years, male, white, stage:iia, alive, 1287 days	11888.2
TCGA-2L-AAQJ-01A	49 years, female, white, stage:iii, dead, 394 days	11528.1
TCGA-2L-AAQM-01A	52 years, male, white, stage:iib, alive, 1383 days	11415.8
TCGA-FB-AAQ3-01A	65 years, female, white, stage:iib, dead, 31 days	11203.3
TCGA-IB-A5SP-01A	77 years, male, white, stage:iia, alive, 482 days	11101.5
TCGA-HV-A5A3-01A	50 years, male, asian, stage:iia, dead, 128 days	10982.5
TCGA-FB-AAPP-01A	71 years, male, white, stage:iib, dead, 485 days	10914.9
TCGA-3A-A9IL-01A	39 years, female, white, stage:i, alive, 2741 days	10825.5
TCGA-HZ-A9TJ-01A	70 years, male, white, stage:iv, alive, 603 days	10721.2
TCGA-3A-A9IN-01A	62 years, female, white, stage:ib, alive, 2084 days	10632.2
TCGA-HV-A5A6-01A	65 years, female, asian, stage:iib, dead, 2036 days	10444.0
TCGA-F2-A8YN-01A	76 years, male, white, stage:iia, alive, 517 days	10172.9
TCGA-FB-AAPU-01A	41 years, female, asian, stage:iia, dead, 381 days	10151.6
TCGA-IB-AAUO-01A	64 years, female, white, stage:iib, dead, 239 days	10030.3
TCGA-HV-AA8V-01A	50 years, male, asian, stage:iib, alive, 920 days	9899.4
TCGA-US-A779-01A	54 years, female, white, stage:iib, dead, 511 days	9893.1
TCGA-3A-A9I9-01A	67 years, male, white, stage:iia, dead, 634 days	9860.8
TCGA-2J-AABE-01A	73 years, male, white, stage:iia, alive, 676 days	9282.6
TCGA-2J-AABT-01A	72 years, female, white, stage:iib, alive, 319 days	9175.1
TCGA-M8-A5N4-01A	48 years, female, stage:iia, alive, 584 days	9173.4
TCGA-US-A77E-01A	73 years, male, white, stage:iib, dead, 430 days	9136.2
TCGA-FB-AAQ0-01A	68 years, male, white, stage:iia, dead, 473 days	8883.0
TCGA-HZ-8315-01A	54 years, female, white, stage:iia, dead, 299 days	8728.4
TCGA-F2-A44G-01A	79 years, female, white, stage:iib, dead, 233 days	8685.9
TCGA-HV-A5A4-01A	72 years, female, asian, stage:iia, alive, 232 days	8682.7
TCGA-FB-AAQ6-01A	85 years, male, white, stage:ia, dead, 244 days	8433.6
TCGA-FB-AAQ2-01A	81 years, female, white, stage:iib, dead, 153 days	8413.2
TCGA-HZ-A4BK-01A	72 years, male, white, stage:iib, alive, 657 days	8354.4
TCGA-XD-AAUI-01A	50 years, female, white, stage:iib, dead, 366 days	8245.6
TCGA-HV-AA8X-01A	75 years, female, asian, stage:iib, dead, 532 days	8145.6
TCGA-HZ-8637-01A	76 years, female, white, stage:iib, dead, 517 days	8008.6
TCGA-US-A776-01A	61 years, male, white, stage:iia, alive, 1216 days	7865.2
TCGA-3A-A9I7-01A	45 years, male, black or african american, stage:iib, alive, 1323 days	7825.7
TCGA-3A-A9IS-01A	67 years, male, white, stage:ib, alive, 998 days	7751.6
TCGA-3A-A9IO-01A	56 years, male, white, alive, 1942 days	7698.9
TCGA-Q3-A5QY-01A	58 years, male, white, stage:iib, alive, 416 days	7698.5
TCGA-FB-AAPQ-01A	65 years, male, white, stage:iib, dead, 1130 days	7562.0
TCGA-FB-AAPZ-01A	54 years, male, white, stage:iib, alive, 716 days	7504.6
TCGA-HZ-8638-01A	84 years, female, white, stage:ia, dead, 151 days	7500.0
TCGA-HZ-A77P-01A	77 years, male, white, stage:iib, alive, 330 days	7478.9
TCGA-US-A77G-01A	64 years, male, white, stage:iib, dead, 12 days	7396.7
TCGA-HZ-A49G-01A	58 years, female, white, stage:iib, alive, 660 days	7307.7
TCGA-HZ-7289-01A	77 years, male, white, stage:iib, dead, 661 days	7307.1
TCGA-S4-A8RM-01A	67 years, male, white, stage:iib, alive, 737 days	7269.1
TCGA-2J-AABA-01A	55 years, male, white, stage:iib, dead, 607 days	7238.4
TCGA-L1-A7W4-01A	48 years, female, white, stage:iib, dead, 278 days	7198.7
TCGA-3E-AAAY-01A	67 years, male, white, stage:iib, alive, 2285 days	7143.6
TCGA-2J-AAB1-01A	65 years, male, white, stage:iib, dead, 66 days	7119.1
TCGA-HZ-A49H-01A	68 years, female, white, stage:iib, alive, 491 days	6882.1
TCGA-HZ-8317-01A	69 years, female, white, stage:iib, dead, 378 days	6871.7
TCGA-2L-AAQI-01A	66 years, male, white, stage:iib, dead, 103 days	6807.8
TCGA-IB-7649-01A	73 years, female, stage:iib, dead, 467 days	6791.2
TCGA-IB-AAUQ-01A	50 years, male, white, stage:iib, dead, 183 days	6778.6
TCGA-3E-AAAZ-01A	71 years, male, white, stage:iia, dead, 2182 days	6668.6
TCGA-FB-A78T-01A	71 years, female, white, stage:iib, dead, 375 days	6628.3
TCGA-H6-A45N-01A	88 years, female, white, stage:iib, dead, 421 days	6343.3
TCGA-FB-A7DR-01A	48 years, male, asian, stage:iia, dead, 353 days	6253.1
TCGA-3A-A9J0-01A	75 years, male, white, stage:iib, alive, 743 days	6199.0
TCGA-2J-AABF-01A	73 years, male, white, stage:iib, dead, 691 days	6197.4
TCGA-FB-A545-01A	72 years, female, white, stage:iib, dead, 732 days	6187.6
TCGA-XN-A8T5-01A	53 years, female, white, stage:ib, alive, 720 days	6168.5
TCGA-IB-AAUW-01A	63 years, female, white, stage:iib, dead, 230 days	6118.7
TCGA-XD-AAUH-01A	57 years, female, white, stage:iib, alive, 395 days	6116.0
TCGA-IB-AAUU-01A	35 years, male, white, stage:iib, alive, 245 days	6115.1
TCGA-2J-AAB4-01A	48 years, male, white, stage:iib, alive, 729 days	6100.1
TCGA-2J-AABO-01A	43 years, male, white, stage:iib, alive, 440 days	6067.8
TCGA-IB-A5SO-01A	71 years, male, white, stage:iib, dead, 365 days	6041.7
TCGA-XN-A8T3-01A	67 years, male, white, stage:ib, alive, 951 days	5953.6
TCGA-IB-A6UF-01A	63 years, male, white, stage:iib, alive, 666 days	5906.8
TCGA-XD-AAUG-01A	66 years, female, white, stage:iv, alive, 420 days	5856.9
TCGA-2J-AABR-01A	60 years, female, white, stage:iia, alive, 438 days	5787.6
TCGA-HZ-A49I-01A	77 years, male, white, stage:iib, dead, 308 days	5698.3
TCGA-HZ-A77O-01A	77 years, female, white, stage:iib, dead, 160 days	5697.2
TCGA-3A-A9IX-01A	40 years, male, white, stage:ia, alive, 1037 days	5687.3
TCGA-HZ-8519-01A	73 years, male, white, stage:ia, alive, 454 days	5624.3
TCGA-YH-A8SY-01A	73 years, female, white, alive, 388 days	5604.0
TCGA-S4-A8RO-01A	75 years, female, white, stage:iib, alive, 525 days	5560.6
TCGA-2L-AAQL-01A	82 years, male, white, stage:iib, dead, 292 days	5558.9
TCGA-3A-A9IB-01A	69 years, female, white, stage:iib, dead, 224 days	5556.1
TCGA-3A-A9IH-01A	66 years, female, white, stage:ia, alive, 1021 days	5546.3
TCGA-2J-AABU-01A	56 years, male, white, stage:iib, dead, 277 days	5531.3
TCGA-IB-8126-01A	80 years, female, white, stage:iii, alive, 462 days	5528.3
TCGA-IB-AAUR-01A	67 years, male, white, stage:iib, alive, 338 days	5520.8
TCGA-2J-AAB8-01A	71 years, male, white, stage:iib, alive, 80 days	5456.5
TCGA-IB-A7M4-01A	81 years, male, white, stage:iib, alive, 483 days	5449.0
TCGA-IB-AAUS-01A	84 years, female, white, stage:iib, alive, 225 days	5417.3
TCGA-2L-AAQE-01A	56 years, male, white, stage:iib, dead, 684 days	5395.5
TCGA-FB-AAPS-01A	62 years, female, white, stage:iib, alive, 228 days	5393.6
TCGA-FB-A4P6-01A	54 years, male, white, stage:iib, alive, 767 days	5324.2
TCGA-FB-A4P5-01A	69 years, female, white, stage:iib, dead, 179 days	5305.0
TCGA-F2-6880-01A	70 years, male, white, stage:iib, alive, 289 days	5292.6
TCGA-IB-AAUT-01A	65 years, male, white, stage:iib, alive, 287 days	5278.6
TCGA-S4-A8RP-01A	77 years, female, white, stage:iib, dead, 702 days	5271.3
TCGA-IB-A6UG-01A	65 years, male, white, stage:iib, dead, 41 days	5270.8
TCGA-3A-A9I5-01A	58 years, male, white, alive, 1794 days	5132.0
TCGA-IB-AAUN-01A	74 years, female, white, stage:ib, dead, 144 days	5089.9
TCGA-IB-AAUM-01A	76 years, male, white, stage:iib, alive, 8 days	5054.6
TCGA-RL-AAAS-01A	60 years, female, white, stage:ib, alive, 9 days	5024.4
TCGA-3A-A9IR-01A	64 years, female, white, stage:ib, alive, 1542 days	4924.6
TCGA-3A-A9IC-01A	61 years, female, white, stage:iib, dead, 738 days	4914.6
TCGA-YY-A8LH-01A	61 years, female, white, stage:iib, alive, 2016 days	4898.7
TCGA-3A-A9IU-01A	65 years, male, white, stage:iib, dead, 458 days	4882.6
TCGA-Z5-AAPL-01A	74 years, female, white, stage:iia, alive, 467 days	4841.9
TCGA-PZ-A5RE-01A	44 years, female, white, stage:iib, dead, 470 days	4780.0
TCGA-2J-AABI-01A	55 years, female, white, stage:iia, alive, 969 days	4733.6
TCGA-YB-A89D-01A	59 years, male, white, stage:iib, alive, 350 days	4707.7
TCGA-IB-7652-01A	49 years, female, asian, stage:iib, alive, 1116 days	4661.9
TCGA-IB-AAUP-01A	68 years, male, white, stage:iib, alive, 431 days	4642.4
TCGA-US-A774-01A	76 years, female, white, stage:iib, dead, 695 days	4627.4
TCGA-2J-AAB9-01A	71 years, female, white, stage:iib, dead, 627 days	4615.5
TCGA-IB-A5SQ-01A	56 years, female, white, stage:ib, dead, 219 days	4527.9
TCGA-OE-A75W-01A	75 years, male, white, stage:iia, dead, 267 days	4516.0
TCGA-IB-7644-01A	65 years, female, white, stage:iv, dead, 394 days	4486.5
TCGA-HZ-A4BH-01A	75 years, male, white, stage:iib, alive, 194 days	4445.7
TCGA-IB-7887-01A	62 years, female, white, stage:iib, dead, 110 days	4432.6
TCGA-HZ-A77Q-01A	55 years, female, white, stage:iib, alive, 33 days	4416.8
TCGA-IB-A7LX-01A	57 years, male, white, stage:iib, dead, 250 days	4257.1
TCGA-HV-A7OP-01A	72 years, male, asian, stage:iib, alive, 978 days	4255.0
TCGA-IB-AAUV-01A	49 years, male, white, stage:iib, alive, 404 days	4216.9
TCGA-2L-AAQA-01A	76 years, male, white, stage:iib, dead, 143 days	4133.7
TCGA-IB-7885-01A	78 years, female, white, stage:iib, alive, 1257 days	4059.2
TCGA-HZ-7923-01A	65 years, male, white, stage:iia, alive, 314 days	4056.8
TCGA-HZ-7924-01A	60 years, female, white, stage:iia, alive, 840 days	4000.6
TCGA-XD-AAUL-01A	56 years, male, white, stage:iia, alive, 498 days	3906.2
TCGA-US-A77J-01A	81 years, female, white, stage:iib, dead, 568 days	3863.7
TCGA-F2-A7TX-01A	77 years, male, white, stage:iib, dead, 95 days	3811.3
TCGA-LB-A9Q5-01A	63 years, female, white, stage:iib, dead, 313 days	3793.3
TCGA-RB-AA9M-01A	43 years, male, white, stage:iib, alive, 286 days	3775.7
TCGA-H6-8124-01A	56 years, female, white, stage:iib, alive, 392 days	3740.1
TCGA-3A-A9IZ-01A	47 years, male, white, stage:iib, dead, 308 days	3712.1
TCGA-HZ-7926-01A	57 years, male, black or african american, stage:iib, dead, 518 days	3701.9
TCGA-2J-AAB6-01A	75 years, male, white, stage:iia, dead, 293 days	3701.5
TCGA-HV-A7OL-01A	70 years, male, asian, stage:iia, alive, 252 days	3661.3
TCGA-3A-A9IJ-01A	65 years, male, white, stage:ib, alive, 1854 days	3608.7
TCGA-IB-A5ST-01A	64 years, female, white, stage:iib, alive, 635 days	3559.7
TCGA-IB-7645-01A	44 years, female, stage:iib, dead, 1502 days	3512.4
TCGA-HZ-8636-01A	58 years, female, white, stage:iv, dead, 545 days	3476.8
TCGA-IB-7654-01A	80 years, male, white, stage:iib, dead, 476 days	3379.6
TCGA-F2-7276-01A	64 years, male, white, stage:iib, dead, 216 days	3317.2
TCGA-FB-A5VM-01A	74 years, male, white, stage:ib, dead, 498 days	3311.3
TCGA-IB-7646-01A	60 years, male, white, stage:iib, dead, 145 days	3245.1
TCGA-IB-7897-01A	54 years, female, white, stage:iib, dead, 486 days	3192.8
TCGA-LB-A8F3-01A	64 years, female, black or african american, stage:iia, alive, 379 days	3187.5
TCGA-IB-7651-01A	64 years, female, white, stage:iib, dead, 603 days	3011.4
TCGA-IB-8127-01A	59 years, male, white, stage:iib, alive, 522 days	2940.0
TCGA-HZ-8001-01A	69 years, male, white, stage:iii, alive, 706 days	2718.4
TCGA-IB-7889-01A	86 years, female, white, stage:iib, dead, 481 days	2648.2
TCGA-HZ-8002-01A	61 years, male, white, stage:iib, dead, 366 days	2627.5
TCGA-HZ-7925-01A	66 years, male, white, stage:iib, dead, 614 days	2564.7
TCGA-IB-7890-01A	73 years, male, stage:ib, dead, 598 days	2493.9
TCGA-2J-AABP-01A	58 years, female, white, stage:iib, alive, 463 days	2439.7
TCGA-HZ-7920-01A	71 years, male, white, stage:ib, dead, 236 days	2347.2
TCGA-2J-AABV-01A	74 years, male, white, stage:iib, dead, 652 days	2297.3
TCGA-IB-7888-01A	66 years, female, black or african american, stage:iia, dead, 1332 days	2174.1
TCGA-HZ-8003-01A	65 years, female, white, stage:iib, dead, 596 days	2156.6
TCGA-HZ-8005-01A	81 years, male, white, stage:iib, dead, 120 days	2132.3
TCGA-IB-A5SS-01A	64 years, female, white, stage:iib, dead, 460 days	2110.2
TCGA-F2-6879-01A	57 years, male, white, stage:iib, dead, 334 days	1986.8
TCGA-HZ-7919-01A	52 years, female, white, stage:iib, dead, 593 days	1938.4
TCGA-IB-7891-01A	49 years, female, white, stage:iib, dead, 913 days	1901.8
TCGA-F2-7273-01A	54 years, male, black or african american, stage:iib, dead, 592 days	1747.7
TCGA-IB-7893-01A	64 years, male, white, stage:iia, dead, 117 days	1740.4
TCGA-HZ-7918-01A	72 years, male, white, stage:iib, alive, 969 days	1574.1
TCGA-HZ-7922-01A	61 years, female, white, stage:iib, alive, 4 days	1535.7
TCGA-IB-7886-01A	80 years, male, white, stage:iib, dead, 123 days	1059.2
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PANCREATIC CANCER - Protein expressionⁱ A mouse-over function shows sample information and annotation data. Click on an image to view it in a full screen mode. Samples can be filtered based on level of antibody staining by selecting one or several of the following categories: high, medium, low and not detected. The assay and annotation is described here. Note that samples used for immunohistochemistry by the Human Protein Atlas do not correspond to samples in the TCGA dataset.

Antibody stainingⁱ Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high. This score is based on the staining intensity and fraction of stained cells. Read more	Antibody HPA053928
Staining
High
Medium
Low
Not detected
Intensity
Strong
Moderate
Weak
Negative
Quantity
>75%
75%-25%
<25%
None
Location
Nuclear
Cytoplasmic/membranous
Cytoplasmic/membranous,nuclear
None
Click images for details