Expression of MT-CO3 in testis cancer - The Human Protein Atlas

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MT-CO3

SUMMARY

TISSUE

CELL TYPE

PATHOLOGY

BRAIN

BLOOD

CELL

TESTIS CANCER - Interactive survival scatter plotⁱ

The Survival Scatter plot shows the clinical status (i.e. dead or alive) for all individuals in the patient cohort, based on the same data that underlies the corresponding Kaplan-Meier plots. Patients that are alive at last time for follow-up are shown in blue and patients who have died during the study are shown in red.

The x-axis shows the expression levels (FPKM) of the investigated gene in the tumor tissue at the time of diagnosis. The y-axis shows the follow-up time after diagnosis (years). Both axes are complimented with kernel density curves demonstrating the data density over the axes. The top density plot shows the expression levels (FPKM) distribution among dead (red) and alive patients (blue). The right density plot shows the data density of the survived years of dead patients with high and low expression levels respectively, stratified using the cutoff indicated by the vertical dashed line through the Survival Scatter plot. This cutoff is automatically defined based on the FPKM cutoff that minimizes the p-score. The cutoff can be changed by dragging the vertical line or by entering a cutoff value in the square labeled "Current cut-off".

Under the Survival Scatter plot the p-score landscape (black curve; left axis) is shown together with dead median separation (red curve; right axis). Dead median separation is the difference in median mRNA expression between patients who have died with high and low expression, respectively. It is calculated as follows: median FPKM expression of dead patients with high expression - median FPKM expression of dead patients with low expression. This is intended to aid the user in visually exploring custom cutoffs and the associated p-scores and dead median separation.

Individual patient data is displayed and can be filtered by clicking on one or more of the category buttons on the top of the page. Categories describing expression level and patient information include: high, low, alive, dead, female, male and tumor stages. The scale of the x-axis can be toggled between linear and log-scale by clicking on the "x log" button. Mouse-over function shows TCGA ID, patient information and mRNA expression (FPKM) for each patient.

& Survival analysisⁱ

MT-CO3 is not prognostic in testis cancer

Stage:

Survival analysis

Current cut offⁱ:
Best expression cut offⁱ: 6826.82
Median expressionⁱ: N/A
Median follow up timeⁱ: N/A
P scoreⁱ N/A
5-year survival highⁱ N/A
5-year survival lowⁱ N/A

TCGA RNA samplesⁱ

Average FPKM

7357.4

Number of samples

134

Samples

Sample	Description	FPKM
TCGA-XE-AAOL-01A	38 years, male, black or african american, stage:i, alive, 13 days	61613.4
TCGA-ZM-AA05-01A	36 years, male, white, stage:iic, alive, 1126 days	54111.0
TCGA-ZM-AA06-01A	45 years, male, white, stage:ib, alive, 1498 days	38464.1
TCGA-ZM-AA0F-01A	35 years, male, white, stage:ia, alive, 681 days	34047.4
TCGA-ZM-AA0N-01A	44 years, male, white, stage:ib, alive, 634 days	33368.8
TCGA-ZM-AA0H-01A	50 years, male, white, stage:is, alive, 1736 days	28319.0
TCGA-ZM-AA0E-01A	39 years, male, white, stage:ia, alive, 811 days	25532.8
TCGA-2G-AAGG-01A	20 years, male, white, stage:iiic, alive, 2611 days	18618.4
TCGA-XE-AAO4-01A	40 years, male, white, stage:ia, alive, 367 days	17973.9
TCGA-2G-AAKD-01A	18 years, male, white, stage:iii, alive, 6340 days	16222.9
TCGA-XE-AAO6-01A	47 years, male, white, stage:ia, alive, 240 days	15607.0
TCGA-ZM-AA0B-01A	32 years, male, white, stage:ia, alive, 838 days	15135.9
TCGA-2G-AAGV-01A	23 years, male, white, alive, 4527 days	10978.1
TCGA-YU-A90Y-01A	23 years, male, black or african american, stage:iiic, dead, 17 days	10836.1
TCGA-ZM-AA0D-01A	34 years, male, white, stage:ia, alive, 848 days	10608.6
TCGA-2G-AAGF-01A	28 years, male, white, stage:is, alive, 2734 days	10366.6
TCGA-2G-AAFM-01A	31 years, male, white, stage:iia, alive, 503 days	10090.1
TCGA-2G-AAKL-01A	26 years, male, white, stage:ii, alive, 7023 days	10064.4
TCGA-2G-AAL7-01A	32 years, male, white, stage:is, alive, 3991 days	9746.8
TCGA-2G-AAGA-01A	38 years, male, white, stage:iia, alive, 2439 days	9561.2
TCGA-2G-AAFL-01A	35 years, male, white, stage:ib, alive, 750 days	9292.8
TCGA-2G-AAFN-01A	26 years, male, white, stage:iiib, alive, 773 days	9238.3
TCGA-4K-AAAL-01A	31 years, male, white, stage:is, alive, 483 days	9123.2
TCGA-YU-A90S-01A	26 years, male, white, stage:ia, alive, 971 days	8998.2
TCGA-W4-A7U4-01A	23 years, male, white, alive, 738 days	8908.2
TCGA-2G-AAG5-01A	36 years, male, white, stage:is, alive, 2299 days	8885.3
TCGA-2G-AAG0-01A	23 years, male, white, stage:is, alive, 1529 days	8791.1
TCGA-VF-A8AD-01A	36 years, male, white, stage:ib, alive, 1006 days	8667.6
TCGA-2G-AAG6-01A	24 years, male, white, stage:is, alive, 2231 days	8383.5
TCGA-2G-AAG8-01A	21 years, male, white, stage:ib, alive, 2289 days	8378.5
TCGA-2G-AAGW-01A	38 years, male, white, stage:is, alive, 4899 days	8220.4
TCGA-2G-AAGM-01A	51 years, male, white, stage:is, alive, 3891 days	8041.2
TCGA-2G-AAKM-01A	14 years, male, white, stage:ii, dead, 6972 days	7914.0
TCGA-WZ-A8D5-01A	38 years, male, white, alive, 774 days	7195.2
TCGA-2G-AAFO-01A	33 years, male, white, stage:iia, alive, 685 days	7192.9
TCGA-2G-AAGZ-01A	27 years, male, white, stage:iiia, alive, 5233 days	7182.2
TCGA-VF-A8AE-01A	39 years, male, white, stage:ia, alive, 727 days	7161.4
TCGA-2G-AAFJ-01A	23 years, male, asian, alive, 792 days	7110.2
TCGA-2G-AAGE-01A	21 years, male, white, stage:is, alive, 2478 days	7048.3
TCGA-2G-AAGO-01A	41 years, male, white, stage:is, alive, 4026 days	7003.5
TCGA-YU-A94I-01A	66 years, male, stage:ia, alive, 536 days	6953.7
TCGA-2G-AAFY-01A	24 years, male, white, stage:iia, alive, 1099 days	6911.2
TCGA-X3-A8G4-01A	33 years, male, white, stage:is, alive, 856 days	6908.5
TCGA-XE-AAOB-01A	27 years, male, white, stage:is, dead, 513 days	6834.2
TCGA-XE-AAOJ-01A	24 years, male, white, stage:is, alive, 1550 days	6819.4
TCGA-2G-AALP-01A	43 years, male, white, stage:iiib, alive, 2645 days	6732.2
TCGA-XY-A89B-01A	35 years, male, white, stage:ia, alive, 471 days	6699.4
TCGA-2G-AAH0-01A	30 years, male, white, stage:is, alive, 5477 days	6686.6
TCGA-YU-AA4L-01A	27 years, male, black or african american, stage:iiic, alive, 1573 days	6477.4
TCGA-4K-AA1I-01A	26 years, male, white, stage:ia, alive, 3 days	6396.5
TCGA-2G-AAFE-01A	37 years, male, white, stage:iia, alive, 4702 days	6250.0
TCGA-VF-A8AB-01A	31 years, male, black or african american, stage:ia, alive, 760 days	6159.9
TCGA-2G-AAGP-01A	33 years, male, white, stage:iia, alive, 4018 days	6130.2
TCGA-S6-A8JX-01A	27 years, male, white, stage:ib, alive, 552 days	6037.0
TCGA-2G-AAFH-01A	38 years, male, white, stage:iib, alive, 1375 days	5978.9
TCGA-2G-AAG3-01A	53 years, male, white, stage:is, alive, 1593 days	5971.2
TCGA-SN-A84W-01A	30 years, male, white, stage:is, alive, 293 days	5902.0
TCGA-2G-AAGY-01A	28 years, male, white, stage:is, alive, 5329 days	5783.2
TCGA-2G-AAH2-01A	20 years, male, white, stage:is, alive, 6060 days	5683.9
TCGA-XE-A8H1-01A	24 years, male, white, stage:is, alive, 209 days	5670.4
TCGA-WZ-A7V4-01A	28 years, male, white, stage:i, alive, 894 days	5619.6
TCGA-2G-AAKG-01A	22 years, male, white, stage:i, alive, 6598 days	5611.6
TCGA-VF-A8A8-01A	18 years, male, white, stage:ia, alive, 1131 days	5583.7
TCGA-4K-AA1H-01A	26 years, male, white, stage:ia, alive, 518 days	5305.5
TCGA-XE-AAOC-01A	31 years, male, white, stage:ia, alive, 270 days	5295.7
TCGA-2G-AAGJ-01A	28 years, male, black or african american, stage:ia, alive, 2938 days	5197.2
TCGA-YU-A90P-01A	25 years, male, white, stage:ia, alive, 2069 days	5118.4
TCGA-2G-AAG7-01A	33 years, male, white, stage:is, alive, 2475 days	5104.6
TCGA-VF-A8A9-01A	31 years, male, white, stage:ia, alive, 1119 days	5085.0
TCGA-2G-AAGS-01A	39 years, male, white, stage:iiib, alive, 4816 days	4986.6
TCGA-XE-AAOD-01A	39 years, male, white, stage:ib, alive, 2058 days	4945.0
TCGA-2G-AAGN-01A	41 years, male, white, stage:iiib, alive, 3656 days	4897.0
TCGA-YU-A90W-01A	45 years, male, white, stage:ia, alive, 1113 days	4846.2
TCGA-XE-A8H4-01A	23 years, male, white, stage:ia, alive, 559 days	4812.7
TCGA-2G-AAG9-01A	25 years, male, white, stage:iiib, alive, 2234 days	4806.1
TCGA-2G-AAKH-01A	19 years, male, white, stage:ii, alive, 6862 days	4754.1
TCGA-2G-AAGI-01A	33 years, male, white, stage:is, alive, 3137 days	4647.9
TCGA-SN-A84Y-01A	18 years, male, white, stage:is, alive, 524 days	4606.0
TCGA-WZ-A7V3-01A	20 years, male, white, stage:i, alive, 753 days	4513.7
TCGA-YU-AA61-01A	29 years, male, white, stage:is, alive, 864 days	4399.1
TCGA-2G-AAFZ-01A	32 years, male, white, stage:iii, alive, 1353 days	4365.1
TCGA-2G-AAH4-01A	34 years, male, white, stage:ii, alive, 6210 days	4294.8
TCGA-YU-A94D-01A	28 years, male, stage:iiib, alive, 2167 days	4179.2
TCGA-YU-A912-01A	34 years, male, black or african american, stage:iiic, alive, 866 days	4128.8
TCGA-2G-AAGT-01A	30 years, male, white, stage:is, alive, 4406 days	4125.6
TCGA-XE-AANR-01A	24 years, male, white, stage:i, alive, 14 days	4118.6
TCGA-YU-A90Q-01A	21 years, male, stage:ib, alive, 1964 days	3927.8
TCGA-XE-AANI-01A	37 years, male, white, stage:is, alive, 1041 days	3913.4
TCGA-2G-AAGC-01A	28 years, male, white, stage:is, alive, 2585 days	3873.6
TCGA-XY-A8S3-01B	24 years, male, white, stage:is, alive, 843 days	3782.4
TCGA-VF-A8AA-01A	51 years, male, white, stage:i, alive, 1146 days	3780.4
TCGA-2G-AAGX-01A	22 years, male, white, stage:ia, alive, 5514 days	3740.2
TCGA-XY-A8S2-01A	67 years, male, white, stage:i, alive, 672 days	3665.5
TCGA-2G-AAFV-01A	31 years, male, white, stage:is, alive, 1389 days	3662.7
TCGA-W4-A7U3-01A	26 years, male, white, alive, 149 days	3489.4
TCGA-2G-AAFI-01A	41 years, male, white, stage:ib, alive, 675 days	3426.7
TCGA-2G-AAF4-01A	30 years, male, white, stage:i, alive, 2315 days	3380.7
TCGA-2G-AAF8-01A	33 years, male, white, stage:ia, alive, 3911 days	3368.0
TCGA-S6-A8JW-01A	37 years, male, white, stage:is, alive, 698 days	3280.6
TCGA-XE-A9SE-01A	35 years, male, white, stage:ia, alive, 708 days	3270.4
TCGA-XE-AANJ-01A	39 years, male, white, stage:is, alive, 2007 days	3142.1
TCGA-SN-A84X-01A	21 years, male, white, stage:is, alive, 312 days	3138.8
TCGA-XE-AANV-01A	52 years, male, stage:ib, alive, 1701 days	3137.6
TCGA-S6-A8JY-01A	27 years, male, white, stage:is, alive, 278 days	3078.5
TCGA-2G-AAFG-01A	30 years, male, white, stage:is, alive, 6183 days	2997.0
TCGA-XE-A8H5-01A	29 years, male, stage:is, alive, 1217 days	2932.2
TCGA-2X-A9D5-01A	49 years, male, white, stage:i, alive, 435 days	2922.8
TCGA-2G-AAHA-01A	48 years, male, white, stage:ib, alive, 3349 days	2821.1
TCGA-SN-A6IS-01A	26 years, male, white, stage:is, alive, 496 days	2720.8
TCGA-2G-AAHN-01A	32 years, male, white, stage:i, alive, 6445 days	2685.0
TCGA-2G-AAH3-01A	20 years, male, white, stage:i, alive, 1822 days	2672.3
TCGA-2X-A9D6-01A	42 years, male, white, stage:i, alive, 607 days	2646.2
TCGA-2G-AAEX-01A	38 years, male, white, stage:is, alive, 1259 days	2618.9
TCGA-2G-AAL5-01A	31 years, male, white, stage:i, alive, 7437 days	2591.7
TCGA-2G-AAHL-01A	26 years, male, white, stage:i, alive, 7081 days	2558.3
TCGA-XE-AAOF-01A	50 years, male, asian, stage:ia, alive, 1268 days	2547.2
TCGA-2G-AAHG-01A	25 years, male, white, stage:i, alive, 1819 days	2472.9
TCGA-SB-A6J6-01A	22 years, male, white, stage:ia, alive, 413 days	2441.3
TCGA-2G-AAGK-01A	20 years, male, white, stage:is, alive, 3621 days	2418.2
TCGA-2G-AAHC-01A	33 years, male, white, stage:is, alive, 5539 days	2352.9
TCGA-WZ-A7V5-01A	27 years, male, white, stage:i, alive, 1061 days	2239.9
TCGA-VF-A8AC-01A	29 years, male, white, stage:ia, alive, 1083 days	2167.4
TCGA-XY-A9T9-01A	37 years, male, white, stage:is, alive, 281 days	2119.7
TCGA-SB-A76C-01A	38 years, male, white, alive, 42 days	2112.4
TCGA-XE-AAO3-01A	33 years, male, asian, stage:i, alive, 2857 days	2000.4
TCGA-W4-A7U2-01A	26 years, male, white, alive, 1263 days	1855.9
TCGA-SO-A8JP-01A	29 years, male, white, stage:i, alive, 540 days	1760.6
TCGA-2G-AAH8-01A	45 years, male, white, stage:iiic, alive, 2248 days	1753.5
TCGA-4K-AA1G-01A	34 years, male, white, stage:is, alive, 436 days	1667.6
TCGA-2G-AAHT-01A	32 years, male, white, stage:is, alive, 542 days	1420.9
TCGA-2G-AAEW-01A	31 years, male, white, stage:is, dead, 618 days	1344.2
TCGA-2G-AAF6-01A	28 years, male, white, stage:is, alive, 3491 days	1319.7
TCGA-2G-AAHP-01A	31 years, male, white, stage:is, alive, 5667 days	1233.5
TCGA-2G-AAF1-01A	28 years, male, asian, stage:is, alive, 1403 days	1105.1
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TESTIS CANCER - Protein expressionⁱ A mouse-over function shows sample information and annotation data. Click on an image to view it in a full screen mode. Samples can be filtered based on level of antibody staining by selecting one or several of the following categories: high, medium, low and not detected. The assay and annotation is described here. Note that samples used for immunohistochemistry by the Human Protein Atlas do not correspond to samples in the TCGA dataset.

Antibody stainingⁱ Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high. This score is based on the staining intensity and fraction of stained cells. Read more	Antibody HPA042788
Staining
High
Medium
Low
Not detected
Intensity
Strong
Moderate
Weak
Negative
Quantity
>75%
75%-25%
<25%
None
Location
Nuclear
Cytoplasmic/membranous
Cytoplasmic/membranous,nuclear
None
Click images for details

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.