Expression of TMSB10 in colorectal cancer

RECTUM ADENOCARCINOMA (READ) - Interactive survival scatter plotⁱ

The Survival Scatter plot shows the clinical status (i.e. dead or alive) for all individuals in the patient cohort, based on the same data that underlies the corresponding Kaplan-Meier plots. Patients that are alive at last time for follow-up are shown in blue and patients who have died during the study are shown in red.

The x-axis shows the expression levels (FPKM) of the investigated gene in the tumor tissue at the time of diagnosis. The y-axis shows the follow-up time after diagnosis (years). Both axes are complimented with kernel density curves demonstrating the data density over the axes. The top density plot shows the expression levels (FPKM) distribution among dead (red) and alive patients (blue). The right density plot shows the data density of the survived years of dead patients with high and low expression levels respectively, stratified using the cutoff indicated by the vertical dashed line through the Survival Scatter plot. This cutoff is automatically defined based on the FPKM cutoff that minimizes the p-score. The cutoff can be changed by dragging the vertical line or by entering a cutoff value in the square labeled "Current cut-off".

Under the Survival Scatter plot the p-score landscape (black curve; left axis) is shown together with dead median separation (red curve; right axis). Dead median separation is the difference in median mRNA expression between patients who have died with high and low expression, respectively. It is calculated as follows: median FPKM expression of dead patients with high expression - median FPKM expression of dead patients with low expression. This is intended to aid the user in visually exploring custom cutoffs and the associated p-scores and dead median separation.

Individual patient data is displayed and can be filtered by clicking on one or more of the category buttons on the top of the page. Categories describing expression level and patient information include: high, low, alive, dead, female, male and tumor stages. The scale of the x-axis can be toggled between linear and log-scale by clicking on the "x log" button. Mouse-over function shows TCGA ID, patient information and mRNA expression (FPKM) for each patient.

& Survival analysisⁱ

Stage:

Survival analysis

Current cut offⁱ:
Best expression cut offⁱ: 2968.5
Median expressionⁱ: N/A
Median follow up timeⁱ: N/A
P scoreⁱ N/A
5-year survival highⁱ N/A
5-year survival lowⁱ N/A

TCGA RNA samplesⁱ

Average FPKM

2983.0

Number of samples

159

Samples

Sample	Description	FPKM
TCGA-DC-6155-01A	31 years, female, white, stage:iiia, alive, 425 days	26179.6
TCGA-AG-3575-01A	51 years, male, stage:ii, alive, 365 days	11754.2
TCGA-AG-3598-01A	69 years, male, stage:iia, alive, 1522 days	7571.0
TCGA-DY-A1H8-01A	77 years, female, white, stage:iiia, dead, 992 days	6258.3
TCGA-F5-6863-01A	71 years, female, white, stage:iiib, dead, 361 days	6034.7
TCGA-AG-3611-01A	72 years, male, stage:iia, alive, 424 days	5613.0
TCGA-AG-3892-01A	57 years, female, stage:i, alive, 396 days	5610.0
TCGA-AG-3583-01A	66 years, male, stage:iv, dead, 610 days	5096.9
TCGA-AG-3591-01A	66 years, female, stage:iia, alive, 1035 days	4947.2
TCGA-AG-3901-01A	67 years, female, stage:iiib, alive, 761 days	4932.3
TCGA-DY-A1DE-01A	56 years, female, white, stage:iia, alive, 3932 days	4883.2
TCGA-DY-A1DG-01A	75 years, male, white, stage:iva, dead, 1566 days	4840.9
TCGA-DC-5337-01A	69 years, male, white, stage:i, alive, 792 days	4567.7
TCGA-BM-6198-01A	73 years, male, white, stage:iiib, alive, 646 days	4374.9
TCGA-AG-3599-01A	70 years, male, stage:i, alive, 366 days	4370.5
TCGA-DT-5265-01A	51 years, male, asian, stage:ii, alive, 384 days	4367.6
TCGA-AH-6897-01A	48 years, male, white, stage:i, alive, 804 days	4319.6
TCGA-AG-3898-01A	61 years, male, stage:iia, alive, 1461 days	4189.9
TCGA-AG-3605-01A	85 years, female, stage:iv, alive, 30 days	4172.2
TCGA-DC-4745-01A	49 years, female, white, stage:iiib, alive, 639 days	4145.6
TCGA-DC-5869-01A	62 years, female, black or african american, stage:iiib, alive, 943 days	4120.0
TCGA-DC-6154-01A	57 years, female, white, stage:iva, alive, 365 days	4079.2
TCGA-AG-3574-01A	89 years, female, stage:ii, dead, 1096 days	3970.4
TCGA-AF-3913-01A	60 years, male, black or african american, stage:iv, dead, 316 days	3959.7
TCGA-AG-A008-01A	50 years, female, stage:i, alive, 424 days	3955.1
TCGA-F5-6814-01A	57 years, male, white, stage:iia, alive, 1131 days	3861.3
TCGA-CL-5918-01A	90 years, female, white, stage:iia, alive, 218 days	3771.8
TCGA-AG-3883-01A	69 years, male, stage:i, alive, 31 days	3733.4
TCGA-AG-3887-01A	68 years, male, stage:iia, alive, 1124 days	3662.1
TCGA-AG-3594-01A	77 years, male, stage:iia, dead, 61 days	3634.2
TCGA-AF-3400-01A	54 years, male, white, stage:iia, alive, 1049 days	3630.3
TCGA-AG-3728-01A	73 years, male, stage:iiib, alive, 912 days	3607.5
TCGA-AH-6544-01A	60 years, male, white, alive, 1173 days	3578.9
TCGA-AG-A00C-01A	49 years, female, stage:iiib, alive, 183 days	3493.1
TCGA-DY-A1DC-01A	72 years, female, white, stage:iia, dead, 1258 days	3481.9
TCGA-AH-6549-01A	66 years, male, white, alive, 532 days	3454.6
TCGA-AG-3593-01A	72 years, female, stage:iia, alive, 1035 days	3453.3
TCGA-F5-6861-01A	60 years, female, white, stage:iia, alive, 1160 days	3434.3
TCGA-AG-4008-01A	63 years, male, stage:iia, alive, 518 days	3334.9
TCGA-AH-6643-01A	50 years, male, white, stage:iiic, dead, 1314 days	3328.2
TCGA-G5-6572-01A	56 years, male, white, dead, 1432 days	3267.6
TCGA-AG-3581-01A	63 years, male, stage:i, alive, 215 days	3242.3
TCGA-AF-5654-01A	73 years, female, white, stage:i, dead, 512 days	3179.6
TCGA-AF-A56N-01A	47 years, female, black or african american, stage:iia, alive, 360 days	3171.2
TCGA-EI-6509-01A	53 years, male, white, stage:iiic, alive, 517 days	3157.1
TCGA-AG-3586-01A	72 years, female, stage:iii, alive, 31 days	3147.5
TCGA-F5-6813-01A	70 years, male, white, stage:iiic, dead, 598 days	3115.0
TCGA-AG-A015-01A	64 years, female, stage:i, alive, 1096 days	3080.5
TCGA-AF-2687-01A	57 years, male, white, stage:iiic, alive, 1427 days	3021.6
TCGA-EI-6917-01A	33 years, male, white, stage:iiia, alive, 531 days	3007.0
TCGA-AG-3894-01A	65 years, male, stage:iia, alive, 426 days	2987.2
TCGA-AG-3580-01A	67 years, male, stage:i, alive, 244 days	2986.3
TCGA-AG-4005-01A	64 years, male, stage:iv, alive, 427 days	2979.4
TCGA-F5-6464-01A	77 years, female, white, stage:iiic, dead, 303 days	2969.3
TCGA-AG-3608-01A	79 years, female, stage:iia, alive, 485 days	2967.7
TCGA-F5-6465-01A	64 years, female, white, stage:iia, alive, 1506 days	2952.6
TCGA-AF-A56L-01A	48 years, female, black or african american, stage:iiic, alive, 2007 days	2950.8
TCGA-AF-3911-01A	48 years, male, white, stage:iiic, alive, 1148 days	2933.5
TCGA-AG-A00Y-01A	68 years, male, stage:iia, alive, 700 days	2891.3
TCGA-AG-3725-01A	90 years, female, stage:iii, alive, 638 days	2869.6
TCGA-AF-6672-01A	43 years, male, white, stage:iv, alive, 748 days	2852.8
TCGA-EF-5831-01A	72 years, male, white, stage:iia, alive, 127 days	2849.5
TCGA-F5-6812-01A	67 years, male, white, stage:iia, alive, 1110 days	2805.9
TCGA-G5-6641-01A	67 years, male, white, stage:iiia, alive, 804 days	2795.9
TCGA-AG-4007-01A	87 years, male, stage:iv, alive, 31 days	2788.8
TCGA-G5-6233-01A	74 years, male, white, dead, 556 days	2777.0
TCGA-AG-3587-01A	65 years, male, stage:i, alive, 1400 days	2774.5
TCGA-AG-A00H-01A	75 years, male, stage:iia, alive, 790 days	2760.7
TCGA-AG-A032-01A	68 years, male, stage:iiib, alive, 1157 days	2728.2
TCGA-CL-4957-01A	79 years, female, dead, 425 days	2721.0
TCGA-EF-5830-01A	54 years, male, white, stage:iib, alive, 106 days	2713.8
TCGA-CI-6620-01A	41 years, female, white, stage:iva, alive, 1009 days	2711.0
TCGA-AH-6644-01A	73 years, male, white, alive, 838 days	2709.9
TCGA-DC-6681-01A	70 years, female, white, stage:iva, alive, 790 days	2681.9
TCGA-AG-4001-01A	74 years, female, stage:iia, alive, 1096 days	2647.7
TCGA-AG-3896-01A	85 years, female, stage:i, alive, 31 days	2644.5
TCGA-DC-4749-01A	57 years, male, white, stage:i, alive, 762 days	2621.4
TCGA-CI-6623-01B	44 years, male, white, stage:i, alive, 1443 days	2587.7
TCGA-EI-6881-01A	60 years, male, white, stage:iiia, alive, 499 days	2580.6
TCGA-AF-4110-01A	77 years, male, white, stage:iva, alive, 912 days	2566.1
TCGA-AG-A025-01A	62 years, female, stage:i, alive, 1520 days	2562.7
TCGA-AF-2690-01A	77 years, female, white, stage:iiic, dead, 524 days	2543.6
TCGA-AG-3902-01A	61 years, male, stage:iia, alive, 974 days	2525.7
TCGA-AG-3881-01A	83 years, female, stage:iia, alive, 579 days	2509.1
TCGA-AG-3609-01A	65 years, female, stage:iiic, alive, 608 days	2502.1
TCGA-AG-A002-01A	35 years, male, stage:i, alive, 638 days	2499.5
TCGA-F5-6864-01A	74 years, female, white, stage:iiib, alive, 379 days	2487.8
TCGA-EI-6508-01A	48 years, female, white, stage:iiib, alive, 636 days	2478.3
TCGA-AF-2692-01A	54 years, female, white, stage:iia, alive, 412 days	2453.0
TCGA-DY-A1DF-01A	73 years, female, white, stage:iiic, dead, 734 days	2394.9
TCGA-DC-6682-01A	57 years, male, white, stage:iia, alive, 762 days	2367.3
TCGA-AG-3612-01A	55 years, female, stage:iiib, alive, 608 days	2338.8
TCGA-DC-6160-01A	68 years, male, white, stage:i, alive, 1339 days	2322.5
TCGA-AF-A56K-01A	56 years, male, black or african american, stage:iia, alive, 2635 days	2313.4
TCGA-EI-6511-01A	52 years, male, white, stage:iiib, alive, 482 days	2309.7
TCGA-AG-3578-01A	76 years, female, stage:iia, alive, 974 days	2278.7
TCGA-EI-6506-01A	78 years, female, white, stage:iia, alive, 625 days	2255.1
TCGA-CI-6619-01B	41 years, male, white, stage:iv, alive, 184 days	2254.8
TCGA-F5-6702-01A	71 years, male, white, stage:iva, alive, 869 days	2244.6
TCGA-DC-6156-01A	62 years, male, white, stage:iva, alive, 943 days	2229.0
TCGA-AF-2693-01A	75 years, male, white, stage:i, alive, 1155 days	2229.0
TCGA-EI-6884-01A	71 years, male, white, stage:iiia, alive, 328 days	2222.0
TCGA-AG-A020-01A	57 years, female, stage:iii, alive, 31 days	2198.0
TCGA-EI-6510-01A	77 years, female, white, alive, 556 days	2197.7
TCGA-CI-6622-01A	74 years, male, white, stage:iib, alive, 1362 days	2195.8
TCGA-CI-6621-01A	63 years, male, white, stage:iiib, alive, 419 days	2188.3
TCGA-AG-A036-01A	71 years, male, stage:iii, alive, 3562 days	2180.3
TCGA-AG-A011-01A	80 years, male, stage:iia, alive, 1126 days	2167.3
TCGA-AH-6903-01A	46 years, male, white, stage:iiib, alive, 592 days	2154.4
TCGA-AG-3999-01A	61 years, female, stage:iiic, alive, 853 days	2153.3
TCGA-AG-3909-01A	69 years, female, stage:iiib, alive, 608 days	2146.8
TCGA-AF-6655-01A	66 years, male, white, stage:iiia, alive, 609 days	2104.6
TCGA-AG-A01N-01A	68 years, female, stage:iv, alive, 943 days	2089.5
TCGA-AG-3582-01A	75 years, male, stage:iv, dead, 1096 days	2088.4
TCGA-AG-3592-01A	68 years, male, stage:iia, alive, 1035 days	2067.1
TCGA-EI-6513-01A	59 years, male, white, stage:iiib, alive, 497 days	2052.8
TCGA-AG-4021-01A	84 years, female, stage:iv, dead, 121 days	2049.1
TCGA-EI-6512-01A	64 years, female, white, stage:iiib, alive, 538 days	2044.7
TCGA-EI-6507-01A	60 years, male, white, stage:iia, alive, 607 days	2038.7
TCGA-CL-5917-01A	71 years, female, white, stage:iiic, alive, 2376 days	2006.4
TCGA-AG-3731-01A	65 years, male, stage:iv, alive, 1126 days	2005.7
TCGA-DC-6157-01A	48 years, male, black or african american, stage:i, alive, 1581 days	2001.5
TCGA-F5-6811-01A	72 years, female, white, stage:iia, alive, 979 days	1980.5
TCGA-AG-3600-01A	62 years, male, stage:iiic, alive, 184 days	1975.9
TCGA-AG-3742-01A	85 years, female, stage:i, alive, 30 days	1966.5
TCGA-AG-3893-01A	74 years, male, stage:iiib, alive, 1065 days	1965.5
TCGA-DY-A0XA-01A	57 years, female, white, stage:iia, alive, 3846 days	1949.4
TCGA-EI-6514-01A	59 years, female, white, stage:iia, alive, 496 days	1941.9
TCGA-EI-6885-01A	57 years, female, white, stage:iv, alive, 415 days	1938.6
TCGA-CI-6624-01C	53 years, female, white, stage:i, alive, 1466 days	1938.3
TCGA-AG-3885-01A	71 years, female, stage:iiib, alive, 546 days	1924.2
TCGA-EI-7002-01A	58 years, male, white, stage:iv, alive, 364 days	1914.1
TCGA-AF-6136-01A	72 years, female, white, stage:iiib, alive, 741 days	1913.8
TCGA-AG-3882-01A	66 years, female, stage:i, alive, 608 days	1912.2
TCGA-AG-A01J-01A	59 years, female, stage:iia, alive, 31 days	1910.4
TCGA-DC-6683-01A	43 years, male, white, stage:iiib, alive, 762 days	1886.6
TCGA-DC-6158-01A	70 years, male, white, stage:i, dead, 334 days	1863.1
TCGA-AF-2691-01A	48 years, female, white, stage:i, alive, 1309 days	1857.7
TCGA-AG-3584-01A	60 years, male, stage:iv, dead, 730 days	1851.6
TCGA-AG-4022-01A	59 years, female, stage:ii, alive, 1400 days	1844.6
TCGA-DY-A1DD-01A	77 years, female, white, stage:iiib, dead, 1741 days	1805.9
TCGA-G5-6235-01A	72 years, male, white, stage:iiib, alive, 1696 days	1796.8
TCGA-EI-6882-01A	59 years, male, white, stage:iia, alive, 262 days	1792.5
TCGA-AG-A016-01A	55 years, male, stage:iv, alive, 276 days	1777.6
TCGA-EI-6883-01A	63 years, male, white, stage:iic, alive, 350 days	1672.5
TCGA-AG-3878-01A	64 years, male, stage:i, alive, 30 days	1635.6
TCGA-AG-A023-01A	62 years, female, stage:iv, dead, 1581 days	1624.2
TCGA-AG-A02G-01A	66 years, male, stage:iv, dead, 1185 days	1618.0
TCGA-AG-3890-01A	62 years, male, stage:i, alive, 518 days	1613.7
TCGA-EI-7004-01A	37 years, female, white, alive, 257 days	1598.4
TCGA-AG-A02X-01A	77 years, male, stage:i, alive, 1247 days	1575.7
TCGA-AH-6547-01A	79 years, female, white, dead, 76 days	1477.0
TCGA-AG-A026-01A	66 years, male, stage:ii, dead, 59 days	1461.9
TCGA-AG-A02N-01A	67 years, male, stage:ii, alive, 1885 days	1364.0
TCGA-AG-3732-01A	78 years, female, stage:i, alive, 1003 days	1299.3
TCGA-F5-6571-01A	62 years, female, white, stage:iia, alive, 1288 days	1254.2
TCGA-AG-A014-01A	86 years, male, stage:i, alive, 485 days	1197.2
TCGA-AG-3727-01A	78 years, female, stage:iii, alive, 30 days	935.5
TCGA-AG-3726-01A	63 years, female, stage:i, alive, 243 days	850.7
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