Expression of RPS12 in colorectal cancer

RECTUM ADENOCARCINOMA (READ) - Interactive survival scatter plotⁱ

The Survival Scatter plot shows the clinical status (i.e. dead or alive) for all individuals in the patient cohort, based on the same data that underlies the corresponding Kaplan-Meier plots. Patients that are alive at last time for follow-up are shown in blue and patients who have died during the study are shown in red.

The x-axis shows the expression levels (FPKM) of the investigated gene in the tumor tissue at the time of diagnosis. The y-axis shows the follow-up time after diagnosis (years). Both axes are complimented with kernel density curves demonstrating the data density over the axes. The top density plot shows the expression levels (FPKM) distribution among dead (red) and alive patients (blue). The right density plot shows the data density of the survived years of dead patients with high and low expression levels respectively, stratified using the cutoff indicated by the vertical dashed line through the Survival Scatter plot. This cutoff is automatically defined based on the FPKM cutoff that minimizes the p-score. The cutoff can be changed by dragging the vertical line or by entering a cutoff value in the square labeled "Current cut-off".

Under the Survival Scatter plot the p-score landscape (black curve; left axis) is shown together with dead median separation (red curve; right axis). Dead median separation is the difference in median mRNA expression between patients who have died with high and low expression, respectively. It is calculated as follows: median FPKM expression of dead patients with high expression - median FPKM expression of dead patients with low expression. This is intended to aid the user in visually exploring custom cutoffs and the associated p-scores and dead median separation.

Individual patient data is displayed and can be filtered by clicking on one or more of the category buttons on the top of the page. Categories describing expression level and patient information include: high, low, alive, dead, female, male and tumor stages. The scale of the x-axis can be toggled between linear and log-scale by clicking on the "x log" button. Mouse-over function shows TCGA ID, patient information and mRNA expression (FPKM) for each patient.

& Survival analysisⁱ

Stage:

Survival analysis

Current cut offⁱ:
Best expression cut offⁱ: 1146.56
Median expressionⁱ: N/A
Median follow up timeⁱ: N/A
P scoreⁱ N/A
5-year survival highⁱ N/A
5-year survival lowⁱ N/A

TCGA RNA samplesⁱ

Average FPKM

1349.8

Number of samples

159

Samples

Sample	Description	FPKM
TCGA-AG-3881-01A	83 years, female, stage:iia, alive, 579 days	2756.5
TCGA-AG-3609-01A	65 years, female, stage:iiic, alive, 608 days	2731.1
TCGA-AG-A02G-01A	66 years, male, stage:iv, dead, 1185 days	2719.4
TCGA-AG-3883-01A	69 years, male, stage:i, alive, 31 days	2556.8
TCGA-EI-6883-01A	63 years, male, white, stage:iic, alive, 350 days	2518.0
TCGA-EI-6917-01A	33 years, male, white, stage:iiia, alive, 531 days	2415.0
TCGA-AF-6136-01A	72 years, female, white, stage:iiib, alive, 741 days	2411.2
TCGA-AG-3999-01A	61 years, female, stage:iiic, alive, 853 days	2396.7
TCGA-EI-7002-01A	58 years, male, white, stage:iv, alive, 364 days	2368.7
TCGA-DY-A0XA-01A	57 years, female, white, stage:iia, alive, 3846 days	2314.0
TCGA-AG-3591-01A	66 years, female, stage:iia, alive, 1035 days	2287.1
TCGA-EF-5830-01A	54 years, male, white, stage:iib, alive, 106 days	2253.1
TCGA-EI-6509-01A	53 years, male, white, stage:iiic, alive, 517 days	2153.1
TCGA-EI-6507-01A	60 years, male, white, stage:iia, alive, 607 days	2101.5
TCGA-DC-4745-01A	49 years, female, white, stage:iiib, alive, 639 days	2065.1
TCGA-AG-A02X-01A	77 years, male, stage:i, alive, 1247 days	2061.6
TCGA-DC-6155-01A	31 years, female, white, stage:iiia, alive, 425 days	2049.2
TCGA-CI-6623-01B	44 years, male, white, stage:i, alive, 1443 days	2004.0
TCGA-CI-6619-01B	41 years, male, white, stage:iv, alive, 184 days	1992.8
TCGA-AF-4110-01A	77 years, male, white, stage:iva, alive, 912 days	1937.0
TCGA-EI-7004-01A	37 years, female, white, alive, 257 days	1908.0
TCGA-DC-5869-01A	62 years, female, black or african american, stage:iiib, alive, 943 days	1891.4
TCGA-AG-3594-01A	77 years, male, stage:iia, dead, 61 days	1890.3
TCGA-AG-3892-01A	57 years, female, stage:i, alive, 396 days	1874.5
TCGA-AG-3583-01A	66 years, male, stage:iv, dead, 610 days	1798.2
TCGA-F5-6571-01A	62 years, female, white, stage:iia, alive, 1288 days	1779.2
TCGA-AG-3612-01A	55 years, female, stage:iiib, alive, 608 days	1738.5
TCGA-AG-3598-01A	69 years, male, stage:iia, alive, 1522 days	1736.0
TCGA-AG-3732-01A	78 years, female, stage:i, alive, 1003 days	1715.4
TCGA-AG-3885-01A	71 years, female, stage:iiib, alive, 546 days	1705.3
TCGA-AG-3896-01A	85 years, female, stage:i, alive, 31 days	1701.7
TCGA-AG-3902-01A	61 years, male, stage:iia, alive, 974 days	1692.2
TCGA-AH-6549-01A	66 years, male, white, alive, 532 days	1681.3
TCGA-EI-6511-01A	52 years, male, white, stage:iiib, alive, 482 days	1680.9
TCGA-AG-3725-01A	90 years, female, stage:iii, alive, 638 days	1677.4
TCGA-DC-6682-01A	57 years, male, white, stage:iia, alive, 762 days	1660.9
TCGA-AG-3611-01A	72 years, male, stage:iia, alive, 424 days	1660.3
TCGA-AH-6643-01A	50 years, male, white, stage:iiic, dead, 1314 days	1645.5
TCGA-AF-6672-01A	43 years, male, white, stage:iv, alive, 748 days	1644.0
TCGA-G5-6572-01A	56 years, male, white, dead, 1432 days	1640.4
TCGA-DC-6157-01A	48 years, male, black or african american, stage:i, alive, 1581 days	1616.6
TCGA-DC-5337-01A	69 years, male, white, stage:i, alive, 792 days	1614.0
TCGA-AG-A023-01A	62 years, female, stage:iv, dead, 1581 days	1609.2
TCGA-AG-3728-01A	73 years, male, stage:iiib, alive, 912 days	1600.8
TCGA-AG-4007-01A	87 years, male, stage:iv, alive, 31 days	1593.0
TCGA-AG-A015-01A	64 years, female, stage:i, alive, 1096 days	1583.4
TCGA-F5-6814-01A	57 years, male, white, stage:iia, alive, 1131 days	1566.5
TCGA-AG-3574-01A	89 years, female, stage:ii, dead, 1096 days	1548.5
TCGA-DC-6154-01A	57 years, female, white, stage:iva, alive, 365 days	1540.5
TCGA-AG-A01N-01A	68 years, female, stage:iv, alive, 943 days	1528.3
TCGA-AH-6644-01A	73 years, male, white, alive, 838 days	1528.0
TCGA-CL-4957-01A	79 years, female, dead, 425 days	1519.3
TCGA-AG-3887-01A	68 years, male, stage:iia, alive, 1124 days	1506.3
TCGA-AG-A00C-01A	49 years, female, stage:iiib, alive, 183 days	1494.8
TCGA-AG-3894-01A	65 years, male, stage:iia, alive, 426 days	1489.2
TCGA-BM-6198-01A	73 years, male, white, stage:iiib, alive, 646 days	1481.1
TCGA-AG-A036-01A	71 years, male, stage:iii, alive, 3562 days	1478.1
TCGA-F5-6861-01A	60 years, female, white, stage:iia, alive, 1160 days	1470.8
TCGA-G5-6233-01A	74 years, male, white, dead, 556 days	1459.7
TCGA-AG-3592-01A	68 years, male, stage:iia, alive, 1035 days	1456.3
TCGA-AF-2687-01A	57 years, male, white, stage:iiic, alive, 1427 days	1448.0
TCGA-AG-A025-01A	62 years, female, stage:i, alive, 1520 days	1441.3
TCGA-AG-4022-01A	59 years, female, stage:ii, alive, 1400 days	1438.2
TCGA-F5-6813-01A	70 years, male, white, stage:iiic, dead, 598 days	1426.6
TCGA-EI-6881-01A	60 years, male, white, stage:iiia, alive, 499 days	1425.4
TCGA-AG-3608-01A	79 years, female, stage:iia, alive, 485 days	1422.5
TCGA-AF-5654-01A	73 years, female, white, stage:i, dead, 512 days	1416.8
TCGA-AG-A00Y-01A	68 years, male, stage:iia, alive, 700 days	1415.5
TCGA-DC-6160-01A	68 years, male, white, stage:i, alive, 1339 days	1394.6
TCGA-EI-6513-01A	59 years, male, white, stage:iiib, alive, 497 days	1389.3
TCGA-DY-A1DG-01A	75 years, male, white, stage:iva, dead, 1566 days	1361.7
TCGA-F5-6864-01A	74 years, female, white, stage:iiib, alive, 379 days	1361.6
TCGA-AG-3581-01A	63 years, male, stage:i, alive, 215 days	1344.3
TCGA-G5-6641-01A	67 years, male, white, stage:iiia, alive, 804 days	1333.9
TCGA-AF-A56L-01A	48 years, female, black or african american, stage:iiic, alive, 2007 days	1327.9
TCGA-CL-5918-01A	90 years, female, white, stage:iia, alive, 218 days	1321.9
TCGA-AH-6903-01A	46 years, male, white, stage:iiib, alive, 592 days	1319.3
TCGA-CI-6622-01A	74 years, male, white, stage:iib, alive, 1362 days	1306.7
TCGA-EI-6884-01A	71 years, male, white, stage:iiia, alive, 328 days	1302.5
TCGA-AG-3727-01A	78 years, female, stage:iii, alive, 30 days	1298.2
TCGA-EI-6512-01A	64 years, female, white, stage:iiib, alive, 538 days	1279.3
TCGA-F5-6863-01A	71 years, female, white, stage:iiib, dead, 361 days	1271.3
TCGA-AG-3882-01A	66 years, female, stage:i, alive, 608 days	1250.3
TCGA-EI-6506-01A	78 years, female, white, stage:iia, alive, 625 days	1245.7
TCGA-AG-A00H-01A	75 years, male, stage:iia, alive, 790 days	1236.6
TCGA-AG-A02N-01A	67 years, male, stage:ii, alive, 1885 days	1233.1
TCGA-AF-2691-01A	48 years, female, white, stage:i, alive, 1309 days	1227.3
TCGA-G5-6235-01A	72 years, male, white, stage:iiib, alive, 1696 days	1218.4
TCGA-EI-6510-01A	77 years, female, white, alive, 556 days	1217.2
TCGA-AG-3909-01A	69 years, female, stage:iiib, alive, 608 days	1188.7
TCGA-DY-A1DE-01A	56 years, female, white, stage:iia, alive, 3932 days	1184.2
TCGA-AG-3586-01A	72 years, female, stage:iii, alive, 31 days	1180.8
TCGA-CI-6620-01A	41 years, female, white, stage:iva, alive, 1009 days	1179.9
TCGA-AG-3742-01A	85 years, female, stage:i, alive, 30 days	1178.3
TCGA-AG-3580-01A	67 years, male, stage:i, alive, 244 days	1177.6
TCGA-AG-3587-01A	65 years, male, stage:i, alive, 1400 days	1152.5
TCGA-AG-A008-01A	50 years, female, stage:i, alive, 424 days	1146.8
TCGA-DY-A1DD-01A	77 years, female, white, stage:iiib, dead, 1741 days	1146.4
TCGA-AG-4005-01A	64 years, male, stage:iv, alive, 427 days	1142.5
TCGA-AG-3878-01A	64 years, male, stage:i, alive, 30 days	1141.1
TCGA-EI-6514-01A	59 years, female, white, stage:iia, alive, 496 days	1139.6
TCGA-DY-A1DC-01A	72 years, female, white, stage:iia, dead, 1258 days	1135.9
TCGA-EF-5831-01A	72 years, male, white, stage:iia, alive, 127 days	1127.9
TCGA-F5-6811-01A	72 years, female, white, stage:iia, alive, 979 days	1125.9
TCGA-AG-A016-01A	55 years, male, stage:iv, alive, 276 days	1116.4
TCGA-F5-6465-01A	64 years, female, white, stage:iia, alive, 1506 days	1109.2
TCGA-AF-2690-01A	77 years, female, white, stage:iiic, dead, 524 days	1093.0
TCGA-AG-3599-01A	70 years, male, stage:i, alive, 366 days	1091.9
TCGA-AG-3582-01A	75 years, male, stage:iv, dead, 1096 days	1091.5
TCGA-AG-3605-01A	85 years, female, stage:iv, alive, 30 days	1075.9
TCGA-AG-3890-01A	62 years, male, stage:i, alive, 518 days	1065.4
TCGA-DC-6156-01A	62 years, male, white, stage:iva, alive, 943 days	1062.5
TCGA-AG-4001-01A	74 years, female, stage:iia, alive, 1096 days	1061.5
TCGA-CI-6621-01A	63 years, male, white, stage:iiib, alive, 419 days	1060.5
TCGA-AF-3913-01A	60 years, male, black or african american, stage:iv, dead, 316 days	1019.6
TCGA-AH-6897-01A	48 years, male, white, stage:i, alive, 804 days	1019.5
TCGA-AF-A56N-01A	47 years, female, black or african american, stage:iia, alive, 360 days	1018.9
TCGA-AG-4021-01A	84 years, female, stage:iv, dead, 121 days	1017.7
TCGA-DC-4749-01A	57 years, male, white, stage:i, alive, 762 days	985.8
TCGA-DC-6683-01A	43 years, male, white, stage:iiib, alive, 762 days	977.9
TCGA-DC-6681-01A	70 years, female, white, stage:iva, alive, 790 days	976.8
TCGA-EI-6508-01A	48 years, female, white, stage:iiib, alive, 636 days	971.2
TCGA-AF-A56K-01A	56 years, male, black or african american, stage:iia, alive, 2635 days	967.6
TCGA-AG-3731-01A	65 years, male, stage:iv, alive, 1126 days	958.6
TCGA-AG-A026-01A	66 years, male, stage:ii, dead, 59 days	933.7
TCGA-EI-6885-01A	57 years, female, white, stage:iv, alive, 415 days	919.0
TCGA-F5-6812-01A	67 years, male, white, stage:iia, alive, 1110 days	912.4
TCGA-AG-A020-01A	57 years, female, stage:iii, alive, 31 days	911.8
TCGA-AF-2693-01A	75 years, male, white, stage:i, alive, 1155 days	905.9
TCGA-AH-6544-01A	60 years, male, white, alive, 1173 days	896.7
TCGA-AF-6655-01A	66 years, male, white, stage:iiia, alive, 609 days	895.1
TCGA-AG-3893-01A	74 years, male, stage:iiib, alive, 1065 days	895.0
TCGA-AG-A014-01A	86 years, male, stage:i, alive, 485 days	888.5
TCGA-AG-3726-01A	63 years, female, stage:i, alive, 243 days	885.8
TCGA-CL-5917-01A	71 years, female, white, stage:iiic, alive, 2376 days	862.1
TCGA-AH-6547-01A	79 years, female, white, dead, 76 days	848.7
TCGA-F5-6464-01A	77 years, female, white, stage:iiic, dead, 303 days	846.1
TCGA-EI-6882-01A	59 years, male, white, stage:iia, alive, 262 days	841.1
TCGA-DC-6158-01A	70 years, male, white, stage:i, dead, 334 days	840.5
TCGA-AF-3911-01A	48 years, male, white, stage:iiic, alive, 1148 days	833.5
TCGA-AF-3400-01A	54 years, male, white, stage:iia, alive, 1049 days	811.6
TCGA-AG-A01J-01A	59 years, female, stage:iia, alive, 31 days	805.9
TCGA-AG-3898-01A	61 years, male, stage:iia, alive, 1461 days	790.1
TCGA-AG-3600-01A	62 years, male, stage:iiic, alive, 184 days	777.9
TCGA-DY-A1H8-01A	77 years, female, white, stage:iiia, dead, 992 days	770.0
TCGA-AG-A032-01A	68 years, male, stage:iiib, alive, 1157 days	769.2
TCGA-F5-6702-01A	71 years, male, white, stage:iva, alive, 869 days	768.6
TCGA-DT-5265-01A	51 years, male, asian, stage:ii, alive, 384 days	747.6
TCGA-AG-3901-01A	67 years, female, stage:iiib, alive, 761 days	705.4
TCGA-AG-3593-01A	72 years, female, stage:iia, alive, 1035 days	703.6
TCGA-AG-3575-01A	51 years, male, stage:ii, alive, 365 days	681.4
TCGA-CI-6624-01C	53 years, female, white, stage:i, alive, 1466 days	665.3
TCGA-AF-2692-01A	54 years, female, white, stage:iia, alive, 412 days	613.4
TCGA-DY-A1DF-01A	73 years, female, white, stage:iiic, dead, 734 days	586.9
TCGA-AG-A002-01A	35 years, male, stage:i, alive, 638 days	504.9
TCGA-AG-4008-01A	63 years, male, stage:iia, alive, 518 days	421.6
TCGA-AG-3584-01A	60 years, male, stage:iv, dead, 730 days	407.8
TCGA-AG-3578-01A	76 years, female, stage:iia, alive, 974 days	356.6
TCGA-AG-A011-01A	80 years, male, stage:iia, alive, 1126 days	354.7
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