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The primary data page shows the detailed antibody staining in 76 different cell types for each analyzed antibody. In addition, for each cell type, a knowledge-based annotated protein expression score based on all analyzed antibodies is displayed furthest to the right. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
The tissues and cell types can be ordered by organ, cell type or alphabetically. If ordered by organ, the tissues are presented in groups according to functional features. If ordered by cell type, the cells are presented in groups related to origin.
This score describes the level of antibody staining observed in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is based on the staining intensity and fraction of stained cells. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
This score describes a knowledge-based best estimate of the protein expression in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is a result of stringent evaluation of immunohistochemical staining pattern, RNA data from internal and external sources and available protein/gene characterization data. More information can be found in Assays & Annotation.
Summarizing texts describe the staining pattern for each antibody based on staining intensity, fraction of stained cells and subcellular localization. More information can be found in Assays & Annotation.
HPA008338
Most normal tissues showed moderate cytoplasmic positivity. Additional membranous or nuclear staining was observed in a few cases. Strong immunoreactivity was observed in gastrointestinal tract, exocrine pancreas, endocrine glands, glandular cells of uterus, Leydig cells and subsets of neuronal cells.
CAB016797
A majority of the normal tissues displayed moderate cytoplasmic positivity, in a few cases with additional membranous staining. Strong positivity was observed in the gastrointestinal tract, adrenal cortical cells, renal tubules and placental trophoblasts. Hepatocytes and bile ducts were weakly stained. Mesenchymal cells were mainly negative.