Expression of S100A11 in pancreatic cancer

PANCREATIC CANCER - Interactive survival scatter plotⁱ

The Survival Scatter plot shows the clinical status (i.e. dead or alive) for all individuals in the patient cohort, based on the same data that underlies the corresponding Kaplan-Meier plots. Patients that are alive at last time for follow-up are shown in blue and patients who have died during the study are shown in red.

The x-axis shows the expression levels (FPKM) of the investigated gene in the tumor tissue at the time of diagnosis. The y-axis shows the follow-up time after diagnosis (years). Both axes are complimented with kernel density curves demonstrating the data density over the axes. The top density plot shows the expression levels (FPKM) distribution among dead (red) and alive patients (blue). The right density plot shows the data density of the survived years of dead patients with high and low expression levels respectively, stratified using the cutoff indicated by the vertical dashed line through the Survival Scatter plot. This cutoff is automatically defined based on the FPKM cutoff that minimizes the p-score. The cutoff can be changed by dragging the vertical line or by entering a cutoff value in the square labeled "Current cut-off".

Under the Survival Scatter plot the p-score landscape (black curve; left axis) is shown together with dead median separation (red curve; right axis). Dead median separation is the difference in median mRNA expression between patients who have died with high and low expression, respectively. It is calculated as follows: median FPKM expression of dead patients with high expression - median FPKM expression of dead patients with low expression. This is intended to aid the user in visually exploring custom cutoffs and the associated p-scores and dead median separation.

Individual patient data is displayed and can be filtered by clicking on one or more of the category buttons on the top of the page. Categories describing expression level and patient information include: high, low, alive, dead, female, male and tumor stages. The scale of the x-axis can be toggled between linear and log-scale by clicking on the "x log" button. Mouse-over function shows TCGA ID, patient information and mRNA expression (FPKM) for each patient.

& Survival analysisⁱ

S100A11 is not prognostic in pancreatic cancer

Stage:

Survival analysis

Current cut offⁱ:
Best expression cut offⁱ: 725.16
Median expressionⁱ: N/A
Median follow up timeⁱ: N/A
P scoreⁱ N/A
5-year survival highⁱ N/A
5-year survival lowⁱ N/A

TCGA RNA samplesⁱ

Average FPKM

1098.0

Number of samples

176

Samples

Sample	Description	FPKM
TCGA-2J-AAB6-01A	75 years, male, white, stage:iia, dead, 293 days	3997.6
TCGA-2J-AABH-01A	61 years, male, white, stage:iia, alive, 1287 days	3242.8
TCGA-HV-A7OL-01A	70 years, male, asian, stage:iia, alive, 252 days	2749.5
TCGA-3A-A9IU-01A	65 years, male, white, stage:iib, dead, 458 days	2693.0
TCGA-FB-AAQ0-01A	68 years, male, white, stage:iia, dead, 473 days	2584.7
TCGA-FB-A5VM-01A	74 years, male, white, stage:ib, dead, 498 days	2457.6
TCGA-2L-AAQL-01A	82 years, male, white, stage:iib, dead, 292 days	2188.0
TCGA-FB-AAPU-01A	41 years, female, asian, stage:iia, dead, 381 days	2131.4
TCGA-HV-AA8X-01A	75 years, female, asian, stage:iib, dead, 532 days	2048.0
TCGA-YY-A8LH-01A	61 years, female, white, stage:iib, alive, 2016 days	2043.6
TCGA-FB-AAQ3-01A	65 years, female, white, stage:iib, dead, 31 days	2010.2
TCGA-2J-AABK-01A	71 years, male, white, stage:iib, alive, 484 days	1930.9
TCGA-2J-AABU-01A	56 years, male, white, stage:iib, dead, 277 days	1896.6
TCGA-IB-AAUO-01A	64 years, female, white, stage:iib, dead, 239 days	1868.4
TCGA-IB-A6UF-01A	63 years, male, white, stage:iib, alive, 666 days	1857.1
TCGA-HZ-A9TJ-01A	70 years, male, white, stage:iv, alive, 603 days	1830.1
TCGA-FB-AAQ6-01A	85 years, male, white, stage:ia, dead, 244 days	1822.2
TCGA-2L-AAQA-01A	76 years, male, white, stage:iib, dead, 143 days	1794.2
TCGA-FB-AAQ1-01A	49 years, male, white, stage:iib, dead, 123 days	1760.5
TCGA-OE-A75W-01A	75 years, male, white, stage:iia, dead, 267 days	1735.3
TCGA-YH-A8SY-01A	73 years, female, white, alive, 388 days	1728.8
TCGA-RB-A7B8-01A	81 years, female, white, stage:iib, dead, 466 days	1698.7
TCGA-FB-AAQ2-01A	81 years, female, white, stage:iib, dead, 153 days	1694.0
TCGA-HV-A5A3-01A	50 years, male, asian, stage:iia, dead, 128 days	1645.5
TCGA-IB-7646-01A	60 years, male, white, stage:iib, dead, 145 days	1627.1
TCGA-IB-A7LX-01A	57 years, male, white, stage:iib, dead, 250 days	1626.8
TCGA-IB-A5SS-01A	64 years, female, white, stage:iib, dead, 460 days	1621.9
TCGA-2J-AAB8-01A	71 years, male, white, stage:iib, alive, 80 days	1609.7
TCGA-PZ-A5RE-01A	44 years, female, white, stage:iib, dead, 470 days	1608.3
TCGA-LB-A8F3-01A	64 years, female, black or african american, stage:iia, alive, 379 days	1586.3
TCGA-Q3-AA2A-01A	64 years, female, white, stage:ib, alive, 95 days	1571.0
TCGA-S4-A8RO-01A	75 years, female, white, stage:iib, alive, 525 days	1563.9
TCGA-M8-A5N4-01A	48 years, female, stage:iia, alive, 584 days	1548.9
TCGA-H6-8124-01A	56 years, female, white, stage:iib, alive, 392 days	1539.3
TCGA-IB-AAUU-01A	35 years, male, white, stage:iib, alive, 245 days	1535.5
TCGA-FB-AAPY-01A	71 years, male, white, stage:iib, dead, 1059 days	1534.4
TCGA-IB-7889-01A	86 years, female, white, stage:iib, dead, 481 days	1534.0
TCGA-FB-A78T-01A	71 years, female, white, stage:iib, dead, 375 days	1529.7
TCGA-2L-AAQJ-01A	49 years, female, white, stage:iii, dead, 394 days	1528.5
TCGA-3A-A9IH-01A	66 years, female, white, stage:ia, alive, 1021 days	1527.1
TCGA-L1-A7W4-01A	48 years, female, white, stage:iib, dead, 278 days	1518.4
TCGA-US-A779-01A	54 years, female, white, stage:iib, dead, 511 days	1501.0
TCGA-HZ-A8P1-01A	81 years, male, white, stage:ib, alive, 7 days	1496.6
TCGA-FB-AAPQ-01A	65 years, male, white, stage:iib, dead, 1130 days	1494.9
TCGA-HV-A7OP-01A	72 years, male, asian, stage:iib, alive, 978 days	1479.0
TCGA-2J-AABO-01A	43 years, male, white, stage:iib, alive, 440 days	1454.6
TCGA-IB-A5SQ-01A	56 years, female, white, stage:ib, dead, 219 days	1445.8
TCGA-2J-AAB4-01A	48 years, male, white, stage:iib, alive, 729 days	1427.9
TCGA-3E-AAAZ-01A	71 years, male, white, stage:iia, dead, 2182 days	1425.1
TCGA-3A-A9IC-01A	61 years, female, white, stage:iib, dead, 738 days	1409.6
TCGA-IB-AAUN-01A	74 years, female, white, stage:ib, dead, 144 days	1381.4
TCGA-2J-AABE-01A	73 years, male, white, stage:iia, alive, 676 days	1374.5
TCGA-US-A77G-01A	64 years, male, white, stage:iib, dead, 12 days	1371.7
TCGA-HZ-8636-01A	58 years, female, white, stage:iv, dead, 545 days	1352.6
TCGA-2L-AAQE-01A	56 years, male, white, stage:iib, dead, 684 days	1341.7
TCGA-3A-A9I9-01A	67 years, male, white, stage:iia, dead, 634 days	1318.0
TCGA-XD-AAUI-01A	50 years, female, white, stage:iib, dead, 366 days	1313.4
TCGA-IB-8127-01A	59 years, male, white, stage:iib, alive, 522 days	1308.7
TCGA-2J-AAB1-01A	65 years, male, white, stage:iib, dead, 66 days	1307.6
TCGA-2L-AAQI-01A	66 years, male, white, stage:iib, dead, 103 days	1299.7
TCGA-HZ-8001-01A	69 years, male, white, stage:iii, alive, 706 days	1278.6
TCGA-2J-AABF-01A	73 years, male, white, stage:iib, dead, 691 days	1276.4
TCGA-HZ-7919-01A	52 years, female, white, stage:iib, dead, 593 days	1273.5
TCGA-IB-A5SP-01A	77 years, male, white, stage:iia, alive, 482 days	1270.7
TCGA-IB-7885-01A	78 years, female, white, stage:iib, alive, 1257 days	1266.1
TCGA-3A-A9J0-01A	75 years, male, white, stage:iib, alive, 743 days	1265.3
TCGA-HV-A5A6-01A	65 years, female, asian, stage:iib, dead, 2036 days	1251.9
TCGA-3A-A9I5-01A	58 years, male, white, alive, 1794 days	1238.5
TCGA-XD-AAUL-01A	56 years, male, white, stage:iia, alive, 498 days	1196.9
TCGA-LB-A7SX-01A	74 years, female, black or african american, stage:iib, dead, 393 days	1185.7
TCGA-IB-7893-01A	64 years, male, white, stage:iia, dead, 117 days	1184.2
TCGA-FB-AAPZ-01A	54 years, male, white, stage:iib, alive, 716 days	1182.5
TCGA-IB-7887-01A	62 years, female, white, stage:iib, dead, 110 days	1176.4
TCGA-HV-AA8V-01A	50 years, male, asian, stage:iib, alive, 920 days	1172.3
TCGA-S4-A8RM-01A	67 years, male, white, stage:iib, alive, 737 days	1165.2
TCGA-F2-6879-01A	57 years, male, white, stage:iib, dead, 334 days	1148.6
TCGA-F2-A8YN-01A	76 years, male, white, stage:iia, alive, 517 days	1147.8
TCGA-XN-A8T3-01A	67 years, male, white, stage:ib, alive, 951 days	1135.2
TCGA-3A-A9I7-01A	45 years, male, black or african american, stage:iib, alive, 1323 days	1118.7
TCGA-HZ-A77O-01A	77 years, female, white, stage:iib, dead, 160 days	1118.1
TCGA-YB-A89D-01A	59 years, male, white, stage:iib, alive, 350 days	1108.7
TCGA-3E-AAAY-01A	67 years, male, white, stage:iib, alive, 2285 days	1101.9
TCGA-HV-A5A4-01A	72 years, female, asian, stage:iia, alive, 232 days	1099.5
TCGA-3A-A9IB-01A	69 years, female, white, stage:iib, dead, 224 days	1096.2
TCGA-HZ-A77Q-01A	55 years, female, white, stage:iib, alive, 33 days	1084.1
TCGA-IB-7888-01A	66 years, female, black or african american, stage:iia, dead, 1332 days	1074.2
TCGA-3A-A9IZ-01A	47 years, male, white, stage:iib, dead, 308 days	1044.8
TCGA-FB-A7DR-01A	48 years, male, asian, stage:iia, dead, 353 days	1041.3
TCGA-F2-A7TX-01A	77 years, male, white, stage:iib, dead, 95 days	1038.1
TCGA-HZ-7925-01A	66 years, male, white, stage:iib, dead, 614 days	1032.1
TCGA-HZ-8315-01A	54 years, female, white, stage:iia, dead, 299 days	1023.3
TCGA-S4-A8RP-01A	77 years, female, white, stage:iib, dead, 702 days	1016.8
TCGA-H8-A6C1-01A	53 years, male, white, stage:iia, alive, 671 days	1015.6
TCGA-IB-7651-01A	64 years, female, white, stage:iib, dead, 603 days	1014.3
TCGA-FB-A545-01A	72 years, female, white, stage:iib, dead, 732 days	1007.8
TCGA-RB-AA9M-01A	43 years, male, white, stage:iib, alive, 286 days	998.8
TCGA-IB-A5ST-01A	64 years, female, white, stage:iib, alive, 635 days	980.9
TCGA-IB-A7M4-01A	81 years, male, white, stage:iib, alive, 483 days	971.0
TCGA-IB-AAUS-01A	84 years, female, white, stage:iib, alive, 225 days	948.2
TCGA-HZ-A49I-01A	77 years, male, white, stage:iib, dead, 308 days	943.5
TCGA-HZ-A4BK-01A	72 years, male, white, stage:iib, alive, 657 days	942.8
TCGA-HZ-7926-01A	57 years, male, black or african american, stage:iib, dead, 518 days	932.4
TCGA-IB-AAUQ-01A	50 years, male, white, stage:iib, dead, 183 days	924.1
TCGA-2J-AABI-01A	55 years, female, white, stage:iia, alive, 969 days	921.9
TCGA-2J-AAB9-01A	71 years, female, white, stage:iib, dead, 627 days	906.8
TCGA-HZ-A4BH-01A	75 years, male, white, stage:iib, alive, 194 days	903.0
TCGA-HZ-7289-01A	77 years, male, white, stage:iib, dead, 661 days	900.7
TCGA-IB-7649-01A	73 years, female, stage:iib, dead, 467 days	883.2
TCGA-RL-AAAS-01A	60 years, female, white, stage:ib, alive, 9 days	873.2
TCGA-IB-7652-01A	49 years, female, asian, stage:iib, alive, 1116 days	872.0
TCGA-IB-7890-01A	73 years, male, stage:ib, dead, 598 days	862.9
TCGA-H6-A45N-01A	88 years, female, white, stage:iib, dead, 421 days	857.3
TCGA-2J-AABP-01A	58 years, female, white, stage:iib, alive, 463 days	816.0
TCGA-2J-AABR-01A	60 years, female, white, stage:iia, alive, 438 days	809.2
TCGA-IB-7891-01A	49 years, female, white, stage:iib, dead, 913 days	779.2
TCGA-IB-7644-01A	65 years, female, white, stage:iv, dead, 394 days	777.5
TCGA-HZ-8005-01A	81 years, male, white, stage:iib, dead, 120 days	776.7
TCGA-F2-A44G-01A	79 years, female, white, stage:iib, dead, 233 days	775.9
TCGA-IB-7886-01A	80 years, male, white, stage:iib, dead, 123 days	767.9
TCGA-HZ-8637-01A	76 years, female, white, stage:iib, dead, 517 days	764.6
TCGA-US-A774-01A	76 years, female, white, stage:iib, dead, 695 days	745.3
TCGA-IB-A6UG-01A	65 years, male, white, stage:iib, dead, 41 days	741.3
TCGA-FB-A4P5-01A	69 years, female, white, stage:iib, dead, 179 days	740.2
TCGA-US-A77E-01A	73 years, male, white, stage:iib, dead, 430 days	738.1
TCGA-2J-AABA-01A	55 years, male, white, stage:iib, dead, 607 days	734.9
TCGA-FB-AAPS-01A	62 years, female, white, stage:iib, alive, 228 days	729.6
TCGA-IB-A5SO-01A	71 years, male, white, stage:iib, dead, 365 days	725.9
TCGA-HZ-7918-01A	72 years, male, white, stage:iib, alive, 969 days	724.5
TCGA-IB-7654-01A	80 years, male, white, stage:iib, dead, 476 days	721.7
TCGA-Q3-A5QY-01A	58 years, male, white, stage:iib, alive, 416 days	713.5
TCGA-HZ-A49G-01A	58 years, female, white, stage:iib, alive, 660 days	706.7
TCGA-XD-AAUH-01A	57 years, female, white, stage:iib, alive, 395 days	703.7
TCGA-IB-7645-01A	44 years, female, stage:iib, dead, 1502 days	699.0
TCGA-HV-A5A5-01A	61 years, female, asian, stage:iib, alive, 289 days	695.8
TCGA-IB-AAUR-01A	67 years, male, white, stage:iib, alive, 338 days	676.7
TCGA-LB-A9Q5-01A	63 years, female, white, stage:iib, dead, 313 days	667.8
TCGA-F2-A44H-01A	65 years, male, white, stage:iia, alive, 586 days	658.7
TCGA-FB-AAPP-01A	71 years, male, white, stage:iib, dead, 485 days	636.2
TCGA-HZ-7922-01A	61 years, female, white, stage:iib, alive, 4 days	602.5
TCGA-HZ-8317-01A	69 years, female, white, stage:iib, dead, 378 days	600.8
TCGA-US-A77J-01A	81 years, female, white, stage:iib, dead, 568 days	594.9
TCGA-FB-A4P6-01A	54 years, male, white, stage:iib, alive, 767 days	586.9
TCGA-IB-AAUP-01A	68 years, male, white, stage:iib, alive, 431 days	574.3
TCGA-IB-AAUT-01A	65 years, male, white, stage:iib, alive, 287 days	571.3
TCGA-HZ-8638-01A	84 years, female, white, stage:ia, dead, 151 days	567.8
TCGA-HZ-8519-01A	73 years, male, white, stage:ia, alive, 454 days	556.8
TCGA-F2-7276-01A	64 years, male, white, stage:iib, dead, 216 days	528.1
TCGA-IB-AAUV-01A	49 years, male, white, stage:iib, alive, 404 days	519.5
TCGA-XD-AAUG-01A	66 years, female, white, stage:iv, alive, 420 days	514.7
TCGA-HZ-A49H-01A	68 years, female, white, stage:iib, alive, 491 days	506.8
TCGA-HZ-8002-01A	61 years, male, white, stage:iib, dead, 366 days	501.4
TCGA-US-A776-01A	61 years, male, white, stage:iia, alive, 1216 days	501.0
TCGA-3A-A9IX-01A	40 years, male, white, stage:ia, alive, 1037 days	488.5
TCGA-F2-7273-01A	54 years, male, black or african american, stage:iib, dead, 592 days	488.0
TCGA-Z5-AAPL-01A	74 years, female, white, stage:iia, alive, 467 days	485.3
TCGA-XN-A8T5-01A	53 years, female, white, stage:ib, alive, 720 days	484.3
TCGA-IB-AAUW-01A	63 years, female, white, stage:iib, dead, 230 days	479.0
TCGA-2J-AABT-01A	72 years, female, white, stage:iib, alive, 319 days	458.9
TCGA-HZ-7924-01A	60 years, female, white, stage:iia, alive, 840 days	443.6
TCGA-HZ-7923-01A	65 years, male, white, stage:iia, alive, 314 days	443.6
TCGA-HZ-A77P-01A	77 years, male, white, stage:iib, alive, 330 days	416.3
TCGA-IB-AAUM-01A	76 years, male, white, stage:iib, alive, 8 days	354.5
TCGA-HZ-7920-01A	71 years, male, white, stage:ib, dead, 236 days	348.7
TCGA-IB-7897-01A	54 years, female, white, stage:iib, dead, 486 days	304.6
TCGA-2J-AABV-01A	74 years, male, white, stage:iib, dead, 652 days	293.2
TCGA-HZ-8003-01A	65 years, female, white, stage:iib, dead, 596 days	266.5
TCGA-IB-8126-01A	80 years, female, white, stage:iii, alive, 462 days	200.1
TCGA-3A-A9IN-01A	62 years, female, white, stage:ib, alive, 2084 days	109.1
TCGA-2L-AAQM-01A	52 years, male, white, stage:iib, alive, 1383 days	85.3
TCGA-3A-A9IV-01A	59 years, female, white, stage:ib, alive, 1103 days	83.3
TCGA-3A-A9IJ-01A	65 years, male, white, stage:ib, alive, 1854 days	72.2
TCGA-3A-A9IL-01A	39 years, female, white, stage:i, alive, 2741 days	68.8
TCGA-3A-A9IO-01A	56 years, male, white, alive, 1942 days	54.7
TCGA-F2-6880-01A	70 years, male, white, stage:iib, alive, 289 days	49.5
TCGA-3A-A9IR-01A	64 years, female, white, stage:ib, alive, 1542 days	19.8
TCGA-3A-A9IS-01A	67 years, male, white, stage:ib, alive, 998 days	12.5
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PANCREATIC CANCER - Protein expressionⁱ A mouse-over function shows sample information and annotation data. Click on an image to view it in a full screen mode. Samples can be filtered based on level of antibody staining by selecting one or several of the following categories: high, medium, low and not detected. The assay and annotation is described here. Note that samples used for immunohistochemistry by the Human Protein Atlas do not correspond to samples in the TCGA dataset.

Antibody stainingⁱ Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high. This score is based on the staining intensity and fraction of stained cells. Read more	Antibody HPA042745	Antibody CAB034320
Staining
High
Medium
Low
Not detected
Intensity
Strong
Moderate
Weak
Negative
Quantity
>75%
75%-25%
<25%
None
Location
Nuclear
Cytoplasmic/membranous
Cytoplasmic/membranous,nuclear
None
Click images for details