Expression of KRT19 in pancreatic cancer

PANCREATIC CANCER - Interactive survival scatter plotⁱ

The Survival Scatter plot shows the clinical status (i.e. dead or alive) for all individuals in the patient cohort, based on the same data that underlies the corresponding Kaplan-Meier plots. Patients that are alive at last time for follow-up are shown in blue and patients who have died during the study are shown in red.

The x-axis shows the expression levels (FPKM) of the investigated gene in the tumor tissue at the time of diagnosis. The y-axis shows the follow-up time after diagnosis (years). Both axes are complimented with kernel density curves demonstrating the data density over the axes. The top density plot shows the expression levels (FPKM) distribution among dead (red) and alive patients (blue). The right density plot shows the data density of the survived years of dead patients with high and low expression levels respectively, stratified using the cutoff indicated by the vertical dashed line through the Survival Scatter plot. This cutoff is automatically defined based on the FPKM cutoff that minimizes the p-score. The cutoff can be changed by dragging the vertical line or by entering a cutoff value in the square labeled "Current cut-off".

Under the Survival Scatter plot the p-score landscape (black curve; left axis) is shown together with dead median separation (red curve; right axis). Dead median separation is the difference in median mRNA expression between patients who have died with high and low expression, respectively. It is calculated as follows: median FPKM expression of dead patients with high expression - median FPKM expression of dead patients with low expression. This is intended to aid the user in visually exploring custom cutoffs and the associated p-scores and dead median separation.

Individual patient data is displayed and can be filtered by clicking on one or more of the category buttons on the top of the page. Categories describing expression level and patient information include: high, low, alive, dead, female, male and tumor stages. The scale of the x-axis can be toggled between linear and log-scale by clicking on the "x log" button. Mouse-over function shows TCGA ID, patient information and mRNA expression (FPKM) for each patient.

& Survival analysisⁱ

KRT19 is prognostic, high expression is unfavorable in pancreatic cancer

Stage:

Survival analysis

Current cut offⁱ:
Best expression cut offⁱ: 334.25
Median expressionⁱ: N/A
Median follow up timeⁱ: N/A
P scoreⁱ N/A
5-year survival highⁱ N/A
5-year survival lowⁱ N/A

TCGA RNA samplesⁱ

Average FPKM

725.2

Number of samples

176

Samples

Sample	Description	FPKM
TCGA-HV-A7OL-01A	70 years, male, asian, stage:iia, alive, 252 days	2480.5
TCGA-FB-A545-01A	72 years, female, white, stage:iib, dead, 732 days	2333.8
TCGA-IB-A7LX-01A	57 years, male, white, stage:iib, dead, 250 days	2237.7
TCGA-FB-AAQ2-01A	81 years, female, white, stage:iib, dead, 153 days	2035.4
TCGA-FB-AAQ1-01A	49 years, male, white, stage:iib, dead, 123 days	1833.2
TCGA-IB-A7M4-01A	81 years, male, white, stage:iib, alive, 483 days	1817.4
TCGA-2J-AABU-01A	56 years, male, white, stage:iib, dead, 277 days	1771.6
TCGA-XD-AAUL-01A	56 years, male, white, stage:iia, alive, 498 days	1634.9
TCGA-OE-A75W-01A	75 years, male, white, stage:iia, dead, 267 days	1597.3
TCGA-PZ-A5RE-01A	44 years, female, white, stage:iib, dead, 470 days	1592.9
TCGA-IB-AAUU-01A	35 years, male, white, stage:iib, alive, 245 days	1583.7
TCGA-US-A779-01A	54 years, female, white, stage:iib, dead, 511 days	1557.8
TCGA-2L-AAQI-01A	66 years, male, white, stage:iib, dead, 103 days	1545.9
TCGA-HZ-A9TJ-01A	70 years, male, white, stage:iv, alive, 603 days	1520.7
TCGA-2J-AABO-01A	43 years, male, white, stage:iib, alive, 440 days	1476.2
TCGA-IB-AAUO-01A	64 years, female, white, stage:iib, dead, 239 days	1461.2
TCGA-2J-AABI-01A	55 years, female, white, stage:iia, alive, 969 days	1427.9
TCGA-HV-A5A3-01A	50 years, male, asian, stage:iia, dead, 128 days	1404.8
TCGA-M8-A5N4-01A	48 years, female, stage:iia, alive, 584 days	1402.4
TCGA-2L-AAQJ-01A	49 years, female, white, stage:iii, dead, 394 days	1361.6
TCGA-3A-A9IU-01A	65 years, male, white, stage:iib, dead, 458 days	1358.9
TCGA-2J-AAB1-01A	65 years, male, white, stage:iib, dead, 66 days	1335.7
TCGA-3A-A9IB-01A	69 years, female, white, stage:iib, dead, 224 days	1324.8
TCGA-H6-8124-01A	56 years, female, white, stage:iib, alive, 392 days	1310.1
TCGA-3A-A9IH-01A	66 years, female, white, stage:ia, alive, 1021 days	1307.8
TCGA-FB-AAQ3-01A	65 years, female, white, stage:iib, dead, 31 days	1303.6
TCGA-FB-A5VM-01A	74 years, male, white, stage:ib, dead, 498 days	1279.0
TCGA-2L-AAQA-01A	76 years, male, white, stage:iib, dead, 143 days	1228.6
TCGA-IB-A5SP-01A	77 years, male, white, stage:iia, alive, 482 days	1219.2
TCGA-2J-AAB6-01A	75 years, male, white, stage:iia, dead, 293 days	1208.9
TCGA-RB-AA9M-01A	43 years, male, white, stage:iib, alive, 286 days	1166.0
TCGA-YH-A8SY-01A	73 years, female, white, alive, 388 days	1162.8
TCGA-FB-AAPU-01A	41 years, female, asian, stage:iia, dead, 381 days	1156.4
TCGA-FB-AAQ0-01A	68 years, male, white, stage:iia, dead, 473 days	1144.8
TCGA-HZ-A8P1-01A	81 years, male, white, stage:ib, alive, 7 days	1104.2
TCGA-FB-AAPY-01A	71 years, male, white, stage:iib, dead, 1059 days	1081.4
TCGA-HZ-A49I-01A	77 years, male, white, stage:iib, dead, 308 days	1077.4
TCGA-YY-A8LH-01A	61 years, female, white, stage:iib, alive, 2016 days	1074.2
TCGA-F2-A7TX-01A	77 years, male, white, stage:iib, dead, 95 days	1063.0
TCGA-HZ-A77O-01A	77 years, female, white, stage:iib, dead, 160 days	1050.3
TCGA-IB-7890-01A	73 years, male, stage:ib, dead, 598 days	1038.5
TCGA-IB-7885-01A	78 years, female, white, stage:iib, alive, 1257 days	1033.0
TCGA-2L-AAQE-01A	56 years, male, white, stage:iib, dead, 684 days	1029.2
TCGA-S4-A8RO-01A	75 years, female, white, stage:iib, alive, 525 days	1026.6
TCGA-IB-A5SS-01A	64 years, female, white, stage:iib, dead, 460 days	1016.2
TCGA-IB-AAUQ-01A	50 years, male, white, stage:iib, dead, 183 days	1015.3
TCGA-HZ-A4BK-01A	72 years, male, white, stage:iib, alive, 657 days	1009.0
TCGA-2J-AABA-01A	55 years, male, white, stage:iib, dead, 607 days	1003.8
TCGA-XD-AAUI-01A	50 years, female, white, stage:iib, dead, 366 days	994.0
TCGA-US-A77G-01A	64 years, male, white, stage:iib, dead, 12 days	992.1
TCGA-HZ-7926-01A	57 years, male, black or african american, stage:iib, dead, 518 days	983.4
TCGA-FB-A78T-01A	71 years, female, white, stage:iib, dead, 375 days	976.5
TCGA-2J-AABH-01A	61 years, male, white, stage:iia, alive, 1287 days	939.4
TCGA-3E-AAAY-01A	67 years, male, white, stage:iib, alive, 2285 days	939.3
TCGA-HV-A5A6-01A	65 years, female, asian, stage:iib, dead, 2036 days	925.8
TCGA-HZ-7922-01A	61 years, female, white, stage:iib, alive, 4 days	918.8
TCGA-HZ-7919-01A	52 years, female, white, stage:iib, dead, 593 days	906.3
TCGA-Q3-AA2A-01A	64 years, female, white, stage:ib, alive, 95 days	898.2
TCGA-3E-AAAZ-01A	71 years, male, white, stage:iia, dead, 2182 days	893.6
TCGA-IB-AAUN-01A	74 years, female, white, stage:ib, dead, 144 days	893.5
TCGA-3A-A9J0-01A	75 years, male, white, stage:iib, alive, 743 days	887.8
TCGA-2L-AAQL-01A	82 years, male, white, stage:iib, dead, 292 days	872.2
TCGA-HZ-7924-01A	60 years, female, white, stage:iia, alive, 840 days	849.8
TCGA-FB-A7DR-01A	48 years, male, asian, stage:iia, dead, 353 days	829.1
TCGA-LB-A8F3-01A	64 years, female, black or african american, stage:iia, alive, 379 days	807.9
TCGA-IB-A5SO-01A	71 years, male, white, stage:iib, dead, 365 days	805.5
TCGA-FB-AAQ6-01A	85 years, male, white, stage:ia, dead, 244 days	800.6
TCGA-3A-A9I7-01A	45 years, male, black or african american, stage:iib, alive, 1323 days	791.4
TCGA-RB-A7B8-01A	81 years, female, white, stage:iib, dead, 466 days	787.7
TCGA-IB-7646-01A	60 years, male, white, stage:iib, dead, 145 days	779.7
TCGA-F2-A44G-01A	79 years, female, white, stage:iib, dead, 233 days	758.7
TCGA-FB-AAPZ-01A	54 years, male, white, stage:iib, alive, 716 days	756.0
TCGA-L1-A7W4-01A	48 years, female, white, stage:iib, dead, 278 days	756.0
TCGA-IB-8127-01A	59 years, male, white, stage:iib, alive, 522 days	752.2
TCGA-YB-A89D-01A	59 years, male, white, stage:iib, alive, 350 days	741.8
TCGA-2J-AABK-01A	71 years, male, white, stage:iib, alive, 484 days	738.1
TCGA-LB-A7SX-01A	74 years, female, black or african american, stage:iib, dead, 393 days	731.2
TCGA-S4-A8RM-01A	67 years, male, white, stage:iib, alive, 737 days	726.6
TCGA-HZ-8638-01A	84 years, female, white, stage:ia, dead, 151 days	724.0
TCGA-S4-A8RP-01A	77 years, female, white, stage:iib, dead, 702 days	723.4
TCGA-XN-A8T3-01A	67 years, male, white, stage:ib, alive, 951 days	709.4
TCGA-2J-AAB9-01A	71 years, female, white, stage:iib, dead, 627 days	694.6
TCGA-IB-7887-01A	62 years, female, white, stage:iib, dead, 110 days	686.7
TCGA-H6-A45N-01A	88 years, female, white, stage:iib, dead, 421 days	675.7
TCGA-IB-7889-01A	86 years, female, white, stage:iib, dead, 481 days	668.3
TCGA-3A-A9IC-01A	61 years, female, white, stage:iib, dead, 738 days	643.6
TCGA-FB-AAPQ-01A	65 years, male, white, stage:iib, dead, 1130 days	639.6
TCGA-HZ-8001-01A	69 years, male, white, stage:iii, alive, 706 days	632.4
TCGA-HZ-8005-01A	81 years, male, white, stage:iib, dead, 120 days	623.7
TCGA-FB-A4P5-01A	69 years, female, white, stage:iib, dead, 179 days	623.3
TCGA-IB-A5SQ-01A	56 years, female, white, stage:ib, dead, 219 days	620.7
TCGA-HV-A7OP-01A	72 years, male, asian, stage:iib, alive, 978 days	612.0
TCGA-2J-AABR-01A	60 years, female, white, stage:iia, alive, 438 days	611.3
TCGA-2J-AAB4-01A	48 years, male, white, stage:iib, alive, 729 days	606.9
TCGA-US-A77J-01A	81 years, female, white, stage:iib, dead, 568 days	597.3
TCGA-2J-AAB8-01A	71 years, male, white, stage:iib, alive, 80 days	578.4
TCGA-HZ-8315-01A	54 years, female, white, stage:iia, dead, 299 days	576.5
TCGA-IB-A6UF-01A	63 years, male, white, stage:iib, alive, 666 days	571.9
TCGA-HZ-A49G-01A	58 years, female, white, stage:iib, alive, 660 days	571.5
TCGA-2J-AABF-01A	73 years, male, white, stage:iib, dead, 691 days	570.2
TCGA-HV-AA8V-01A	50 years, male, asian, stage:iib, alive, 920 days	560.5
TCGA-2J-AABE-01A	73 years, male, white, stage:iia, alive, 676 days	559.5
TCGA-US-A77E-01A	73 years, male, white, stage:iib, dead, 430 days	552.5
TCGA-LB-A9Q5-01A	63 years, female, white, stage:iib, dead, 313 days	551.8
TCGA-IB-A6UG-01A	65 years, male, white, stage:iib, dead, 41 days	544.9
TCGA-HV-A5A4-01A	72 years, female, asian, stage:iia, alive, 232 days	544.1
TCGA-US-A774-01A	76 years, female, white, stage:iib, dead, 695 days	536.6
TCGA-HV-A5A5-01A	61 years, female, asian, stage:iib, alive, 289 days	533.2
TCGA-HZ-A4BH-01A	75 years, male, white, stage:iib, alive, 194 days	527.2
TCGA-3A-A9IZ-01A	47 years, male, white, stage:iib, dead, 308 days	523.5
TCGA-IB-7893-01A	64 years, male, white, stage:iia, dead, 117 days	507.5
TCGA-F2-A8YN-01A	76 years, male, white, stage:iia, alive, 517 days	489.3
TCGA-HZ-7289-01A	77 years, male, white, stage:iib, dead, 661 days	488.8
TCGA-RL-AAAS-01A	60 years, female, white, stage:ib, alive, 9 days	487.5
TCGA-IB-7886-01A	80 years, male, white, stage:iib, dead, 123 days	470.3
TCGA-HV-AA8X-01A	75 years, female, asian, stage:iib, dead, 532 days	469.6
TCGA-Q3-A5QY-01A	58 years, male, white, stage:iib, alive, 416 days	466.1
TCGA-IB-7654-01A	80 years, male, white, stage:iib, dead, 476 days	461.6
TCGA-F2-6879-01A	57 years, male, white, stage:iib, dead, 334 days	442.0
TCGA-IB-7649-01A	73 years, female, stage:iib, dead, 467 days	418.8
TCGA-IB-AAUW-01A	63 years, female, white, stage:iib, dead, 230 days	418.1
TCGA-3A-A9IX-01A	40 years, male, white, stage:ia, alive, 1037 days	408.8
TCGA-IB-7651-01A	64 years, female, white, stage:iib, dead, 603 days	398.4
TCGA-HZ-A77Q-01A	55 years, female, white, stage:iib, alive, 33 days	392.2
TCGA-XN-A8T5-01A	53 years, female, white, stage:ib, alive, 720 days	382.4
TCGA-HZ-8636-01A	58 years, female, white, stage:iv, dead, 545 days	376.4
TCGA-Z5-AAPL-01A	74 years, female, white, stage:iia, alive, 467 days	374.7
TCGA-IB-7644-01A	65 years, female, white, stage:iv, dead, 394 days	349.4
TCGA-HZ-7925-01A	66 years, male, white, stage:iib, dead, 614 days	343.7
TCGA-HZ-8317-01A	69 years, female, white, stage:iib, dead, 378 days	337.1
TCGA-IB-AAUP-01A	68 years, male, white, stage:iib, alive, 431 days	331.4
TCGA-IB-AAUR-01A	67 years, male, white, stage:iib, alive, 338 days	318.6
TCGA-3A-A9I9-01A	67 years, male, white, stage:iia, dead, 634 days	314.2
TCGA-US-A776-01A	61 years, male, white, stage:iia, alive, 1216 days	304.9
TCGA-3A-A9I5-01A	58 years, male, white, alive, 1794 days	300.0
TCGA-FB-AAPS-01A	62 years, female, white, stage:iib, alive, 228 days	290.8
TCGA-FB-A4P6-01A	54 years, male, white, stage:iib, alive, 767 days	284.3
TCGA-H8-A6C1-01A	53 years, male, white, stage:iia, alive, 671 days	284.0
TCGA-HZ-A77P-01A	77 years, male, white, stage:iib, alive, 330 days	274.3
TCGA-IB-AAUT-01A	65 years, male, white, stage:iib, alive, 287 days	272.7
TCGA-F2-7276-01A	64 years, male, white, stage:iib, dead, 216 days	271.5
TCGA-HZ-A49H-01A	68 years, female, white, stage:iib, alive, 491 days	259.2
TCGA-IB-AAUS-01A	84 years, female, white, stage:iib, alive, 225 days	257.8
TCGA-2J-AABT-01A	72 years, female, white, stage:iib, alive, 319 days	254.7
TCGA-IB-7645-01A	44 years, female, stage:iib, dead, 1502 days	254.0
TCGA-F2-A44H-01A	65 years, male, white, stage:iia, alive, 586 days	247.2
TCGA-2L-AAQM-01A	52 years, male, white, stage:iib, alive, 1383 days	235.9
TCGA-F2-7273-01A	54 years, male, black or african american, stage:iib, dead, 592 days	229.1
TCGA-HZ-7920-01A	71 years, male, white, stage:ib, dead, 236 days	223.1
TCGA-IB-7652-01A	49 years, female, asian, stage:iib, alive, 1116 days	222.8
TCGA-IB-A5ST-01A	64 years, female, white, stage:iib, alive, 635 days	222.4
TCGA-IB-7891-01A	49 years, female, white, stage:iib, dead, 913 days	221.2
TCGA-FB-AAPP-01A	71 years, male, white, stage:iib, dead, 485 days	218.2
TCGA-IB-7888-01A	66 years, female, black or african american, stage:iia, dead, 1332 days	199.9
TCGA-XD-AAUH-01A	57 years, female, white, stage:iib, alive, 395 days	190.6
TCGA-2J-AABV-01A	74 years, male, white, stage:iib, dead, 652 days	188.4
TCGA-HZ-8637-01A	76 years, female, white, stage:iib, dead, 517 days	168.3
TCGA-XD-AAUG-01A	66 years, female, white, stage:iv, alive, 420 days	167.2
TCGA-HZ-8002-01A	61 years, male, white, stage:iib, dead, 366 days	165.7
TCGA-HZ-7923-01A	65 years, male, white, stage:iia, alive, 314 days	162.2
TCGA-HZ-8519-01A	73 years, male, white, stage:ia, alive, 454 days	136.1
TCGA-IB-7897-01A	54 years, female, white, stage:iib, dead, 486 days	131.5
TCGA-HZ-8003-01A	65 years, female, white, stage:iib, dead, 596 days	103.3
TCGA-IB-AAUM-01A	76 years, male, white, stage:iib, alive, 8 days	102.6
TCGA-HZ-7918-01A	72 years, male, white, stage:iib, alive, 969 days	73.4
TCGA-3A-A9IL-01A	39 years, female, white, stage:i, alive, 2741 days	61.6
TCGA-IB-8126-01A	80 years, female, white, stage:iii, alive, 462 days	49.4
TCGA-IB-AAUV-01A	49 years, male, white, stage:iib, alive, 404 days	47.3
TCGA-3A-A9IV-01A	59 years, female, white, stage:ib, alive, 1103 days	30.6
TCGA-3A-A9IO-01A	56 years, male, white, alive, 1942 days	19.2
TCGA-F2-6880-01A	70 years, male, white, stage:iib, alive, 289 days	16.4
TCGA-3A-A9IN-01A	62 years, female, white, stage:ib, alive, 2084 days	15.7
TCGA-3A-A9IJ-01A	65 years, male, white, stage:ib, alive, 1854 days	8.6
TCGA-2J-AABP-01A	58 years, female, white, stage:iib, alive, 463 days	2.6
TCGA-3A-A9IR-01A	64 years, female, white, stage:ib, alive, 1542 days	2.1
TCGA-3A-A9IS-01A	67 years, male, white, stage:ib, alive, 998 days	0.2
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PANCREATIC CANCER - Protein expressionⁱ A mouse-over function shows sample information and annotation data. Click on an image to view it in a full screen mode. Samples can be filtered based on level of antibody staining by selecting one or several of the following categories: high, medium, low and not detected. The assay and annotation is described here. Note that samples used for immunohistochemistry by the Human Protein Atlas do not correspond to samples in the TCGA dataset.

Antibody stainingⁱ Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high. This score is based on the staining intensity and fraction of stained cells. Read more	Antibody HPA002465	Antibody CAB000031
Staining
High
Medium
Low
Not detected
Intensity
Strong
Moderate
Weak
Negative
Quantity
>75%
75%-25%
<25%
None
Location
Nuclear
Cytoplasmic/membranous
Cytoplasmic/membranous,nuclear
None
Click images for details