Expression of RPS4X in colorectal cancer

RECTUM ADENOCARCINOMA (READ) - Interactive survival scatter plotⁱ

The Survival Scatter plot shows the clinical status (i.e. dead or alive) for all individuals in the patient cohort, based on the same data that underlies the corresponding Kaplan-Meier plots. Patients that are alive at last time for follow-up are shown in blue and patients who have died during the study are shown in red.

The x-axis shows the expression levels (FPKM) of the investigated gene in the tumor tissue at the time of diagnosis. The y-axis shows the follow-up time after diagnosis (years). Both axes are complimented with kernel density curves demonstrating the data density over the axes. The top density plot shows the expression levels (FPKM) distribution among dead (red) and alive patients (blue). The right density plot shows the data density of the survived years of dead patients with high and low expression levels respectively, stratified using the cutoff indicated by the vertical dashed line through the Survival Scatter plot. This cutoff is automatically defined based on the FPKM cutoff that minimizes the p-score. The cutoff can be changed by dragging the vertical line or by entering a cutoff value in the square labeled "Current cut-off".

Under the Survival Scatter plot the p-score landscape (black curve; left axis) is shown together with dead median separation (red curve; right axis). Dead median separation is the difference in median mRNA expression between patients who have died with high and low expression, respectively. It is calculated as follows: median FPKM expression of dead patients with high expression - median FPKM expression of dead patients with low expression. This is intended to aid the user in visually exploring custom cutoffs and the associated p-scores and dead median separation.

Individual patient data is displayed and can be filtered by clicking on one or more of the category buttons on the top of the page. Categories describing expression level and patient information include: high, low, alive, dead, female, male and tumor stages. The scale of the x-axis can be toggled between linear and log-scale by clicking on the "x log" button. Mouse-over function shows TCGA ID, patient information and mRNA expression (FPKM) for each patient.

& Survival analysisⁱ

Stage:

Survival analysis

Current cut offⁱ:
Best expression cut offⁱ: 704.07
Median expressionⁱ: N/A
Median follow up timeⁱ: N/A
P scoreⁱ N/A
5-year survival highⁱ N/A
5-year survival lowⁱ N/A

TCGA RNA samplesⁱ

Average FPKM

780.3

Number of samples

159

Samples

Sample	Description	FPKM
TCGA-AG-3605-01A	85 years, female, stage:iv, alive, 30 days	3428.7
TCGA-AG-3609-01A	65 years, female, stage:iiic, alive, 608 days	2227.5
TCGA-AG-3574-01A	89 years, female, stage:ii, dead, 1096 days	1915.4
TCGA-DC-4745-01A	49 years, female, white, stage:iiib, alive, 639 days	1801.5
TCGA-AG-3608-01A	79 years, female, stage:iia, alive, 485 days	1762.7
TCGA-DY-A1DD-01A	77 years, female, white, stage:iiib, dead, 1741 days	1587.9
TCGA-CL-5917-01A	71 years, female, white, stage:iiic, alive, 2376 days	1456.7
TCGA-AG-A023-01A	62 years, female, stage:iv, dead, 1581 days	1450.6
TCGA-AG-3881-01A	83 years, female, stage:iia, alive, 579 days	1436.7
TCGA-DC-6154-01A	57 years, female, white, stage:iva, alive, 365 days	1424.8
TCGA-AG-A00C-01A	49 years, female, stage:iiib, alive, 183 days	1421.6
TCGA-AG-4022-01A	59 years, female, stage:ii, alive, 1400 days	1412.5
TCGA-DC-5869-01A	62 years, female, black or african american, stage:iiib, alive, 943 days	1405.5
TCGA-AF-2691-01A	48 years, female, white, stage:i, alive, 1309 days	1398.4
TCGA-AF-5654-01A	73 years, female, white, stage:i, dead, 512 days	1327.8
TCGA-DY-A0XA-01A	57 years, female, white, stage:iia, alive, 3846 days	1302.2
TCGA-AG-3999-01A	61 years, female, stage:iiic, alive, 853 days	1256.7
TCGA-AG-3582-01A	75 years, male, stage:iv, dead, 1096 days	1232.0
TCGA-AF-6136-01A	72 years, female, white, stage:iiib, alive, 741 days	1218.7
TCGA-AG-3612-01A	55 years, female, stage:iiib, alive, 608 days	1172.3
TCGA-AG-3611-01A	72 years, male, stage:iia, alive, 424 days	1171.6
TCGA-AG-3898-01A	61 years, male, stage:iia, alive, 1461 days	1126.3
TCGA-AG-3893-01A	74 years, male, stage:iiib, alive, 1065 days	1108.8
TCGA-AG-3882-01A	66 years, female, stage:i, alive, 608 days	1088.7
TCGA-DC-5337-01A	69 years, male, white, stage:i, alive, 792 days	1087.7
TCGA-EI-6512-01A	64 years, female, white, stage:iiib, alive, 538 days	1070.9
TCGA-AG-3742-01A	85 years, female, stage:i, alive, 30 days	1046.1
TCGA-DC-6682-01A	57 years, male, white, stage:iia, alive, 762 days	1028.1
TCGA-AG-A014-01A	86 years, male, stage:i, alive, 485 days	1017.0
TCGA-CL-5918-01A	90 years, female, white, stage:iia, alive, 218 days	992.0
TCGA-AG-3896-01A	85 years, female, stage:i, alive, 31 days	989.9
TCGA-AF-2692-01A	54 years, female, white, stage:iia, alive, 412 days	985.9
TCGA-AG-A008-01A	50 years, female, stage:i, alive, 424 days	985.2
TCGA-AH-6903-01A	46 years, male, white, stage:iiib, alive, 592 days	978.5
TCGA-AG-3892-01A	57 years, female, stage:i, alive, 396 days	962.5
TCGA-DC-6155-01A	31 years, female, white, stage:iiia, alive, 425 days	961.1
TCGA-AG-3591-01A	66 years, female, stage:iia, alive, 1035 days	960.3
TCGA-AG-4008-01A	63 years, male, stage:iia, alive, 518 days	957.8
TCGA-EI-6514-01A	59 years, female, white, stage:iia, alive, 496 days	957.3
TCGA-EI-7002-01A	58 years, male, white, stage:iv, alive, 364 days	924.3
TCGA-AG-3583-01A	66 years, male, stage:iv, dead, 610 days	902.5
TCGA-AG-A015-01A	64 years, female, stage:i, alive, 1096 days	897.7
TCGA-F5-6465-01A	64 years, female, white, stage:iia, alive, 1506 days	889.1
TCGA-DY-A1H8-01A	77 years, female, white, stage:iiia, dead, 992 days	863.8
TCGA-AG-3732-01A	78 years, female, stage:i, alive, 1003 days	860.6
TCGA-AF-4110-01A	77 years, male, white, stage:iva, alive, 912 days	850.2
TCGA-DT-5265-01A	51 years, male, asian, stage:ii, alive, 384 days	848.2
TCGA-AG-3725-01A	90 years, female, stage:iii, alive, 638 days	841.2
TCGA-AG-3594-01A	77 years, male, stage:iia, dead, 61 days	837.8
TCGA-DC-6681-01A	70 years, female, white, stage:iva, alive, 790 days	833.7
TCGA-F5-6863-01A	71 years, female, white, stage:iiib, dead, 361 days	833.2
TCGA-AG-3902-01A	61 years, male, stage:iia, alive, 974 days	815.0
TCGA-AG-3885-01A	71 years, female, stage:iiib, alive, 546 days	813.6
TCGA-AG-3586-01A	72 years, female, stage:iii, alive, 31 days	801.6
TCGA-AG-3587-01A	65 years, male, stage:i, alive, 1400 days	799.9
TCGA-AF-A56N-01A	47 years, female, black or african american, stage:iia, alive, 360 days	797.7
TCGA-AG-4001-01A	74 years, female, stage:iia, alive, 1096 days	795.0
TCGA-CL-4957-01A	79 years, female, dead, 425 days	793.8
TCGA-AG-A025-01A	62 years, female, stage:i, alive, 1520 days	782.2
TCGA-AF-3913-01A	60 years, male, black or african american, stage:iv, dead, 316 days	781.9
TCGA-EI-6883-01A	63 years, male, white, stage:iic, alive, 350 days	780.2
TCGA-DY-A1DF-01A	73 years, female, white, stage:iiic, dead, 734 days	777.2
TCGA-F5-6571-01A	62 years, female, white, stage:iia, alive, 1288 days	776.7
TCGA-EI-6917-01A	33 years, male, white, stage:iiia, alive, 531 days	773.9
TCGA-F5-6861-01A	60 years, female, white, stage:iia, alive, 1160 days	767.4
TCGA-AH-6897-01A	48 years, male, white, stage:i, alive, 804 days	757.3
TCGA-AH-6643-01A	50 years, male, white, stage:iiic, dead, 1314 days	748.7
TCGA-AG-A01J-01A	59 years, female, stage:iia, alive, 31 days	747.1
TCGA-AG-3600-01A	62 years, male, stage:iiic, alive, 184 days	743.0
TCGA-AG-A02G-01A	66 years, male, stage:iv, dead, 1185 days	728.9
TCGA-AG-3728-01A	73 years, male, stage:iiib, alive, 912 days	723.9
TCGA-AG-3593-01A	72 years, female, stage:iia, alive, 1035 days	721.1
TCGA-AG-3887-01A	68 years, male, stage:iia, alive, 1124 days	707.8
TCGA-AF-2690-01A	77 years, female, white, stage:iiic, dead, 524 days	706.3
TCGA-EI-6509-01A	53 years, male, white, stage:iiic, alive, 517 days	701.8
TCGA-EI-6506-01A	78 years, female, white, stage:iia, alive, 625 days	700.1
TCGA-DC-6683-01A	43 years, male, white, stage:iiib, alive, 762 days	699.3
TCGA-AF-A56L-01A	48 years, female, black or african american, stage:iiic, alive, 2007 days	698.4
TCGA-AG-4005-01A	64 years, male, stage:iv, alive, 427 days	693.7
TCGA-EI-6511-01A	52 years, male, white, stage:iiib, alive, 482 days	690.2
TCGA-AF-6672-01A	43 years, male, white, stage:iv, alive, 748 days	683.3
TCGA-EF-5830-01A	54 years, male, white, stage:iib, alive, 106 days	683.1
TCGA-AF-3400-01A	54 years, male, white, stage:iia, alive, 1049 days	679.7
TCGA-EI-6510-01A	77 years, female, white, alive, 556 days	678.1
TCGA-AG-A01N-01A	68 years, female, stage:iv, alive, 943 days	677.0
TCGA-G5-6233-01A	74 years, male, white, dead, 556 days	674.1
TCGA-AG-3901-01A	67 years, female, stage:iiib, alive, 761 days	670.0
TCGA-AH-6544-01A	60 years, male, white, alive, 1173 days	669.9
TCGA-AG-3598-01A	69 years, male, stage:iia, alive, 1522 days	659.9
TCGA-AG-3894-01A	65 years, male, stage:iia, alive, 426 days	650.5
TCGA-G5-6235-01A	72 years, male, white, stage:iiib, alive, 1696 days	649.2
TCGA-AF-A56K-01A	56 years, male, black or african american, stage:iia, alive, 2635 days	647.2
TCGA-EI-6885-01A	57 years, female, white, stage:iv, alive, 415 days	644.6
TCGA-AG-3592-01A	68 years, male, stage:iia, alive, 1035 days	635.7
TCGA-AG-3581-01A	63 years, male, stage:i, alive, 215 days	629.8
TCGA-AG-3726-01A	63 years, female, stage:i, alive, 243 days	626.3
TCGA-AG-3575-01A	51 years, male, stage:ii, alive, 365 days	613.9
TCGA-AG-3883-01A	69 years, male, stage:i, alive, 31 days	610.1
TCGA-EI-6513-01A	59 years, male, white, stage:iiib, alive, 497 days	604.4
TCGA-DC-6158-01A	70 years, male, white, stage:i, dead, 334 days	602.7
TCGA-AG-3909-01A	69 years, female, stage:iiib, alive, 608 days	593.3
TCGA-AH-6644-01A	73 years, male, white, alive, 838 days	593.1
TCGA-AG-3890-01A	62 years, male, stage:i, alive, 518 days	585.6
TCGA-CI-6620-01A	41 years, female, white, stage:iva, alive, 1009 days	580.0
TCGA-DY-A1DG-01A	75 years, male, white, stage:iva, dead, 1566 days	574.9
TCGA-EI-7004-01A	37 years, female, white, alive, 257 days	571.4
TCGA-CI-6623-01B	44 years, male, white, stage:i, alive, 1443 days	570.9
TCGA-AG-3580-01A	67 years, male, stage:i, alive, 244 days	570.3
TCGA-BM-6198-01A	73 years, male, white, stage:iiib, alive, 646 days	568.1
TCGA-F5-6814-01A	57 years, male, white, stage:iia, alive, 1131 days	563.8
TCGA-AG-A020-01A	57 years, female, stage:iii, alive, 31 days	560.5
TCGA-F5-6464-01A	77 years, female, white, stage:iiic, dead, 303 days	554.7
TCGA-F5-6813-01A	70 years, male, white, stage:iiic, dead, 598 days	552.1
TCGA-AF-6655-01A	66 years, male, white, stage:iiia, alive, 609 days	541.7
TCGA-AG-3878-01A	64 years, male, stage:i, alive, 30 days	533.3
TCGA-AF-2693-01A	75 years, male, white, stage:i, alive, 1155 days	531.9
TCGA-F5-6864-01A	74 years, female, white, stage:iiib, alive, 379 days	529.5
TCGA-AF-3911-01A	48 years, male, white, stage:iiic, alive, 1148 days	528.5
TCGA-DC-6157-01A	48 years, male, black or african american, stage:i, alive, 1581 days	526.8
TCGA-AG-4007-01A	87 years, male, stage:iv, alive, 31 days	525.5
TCGA-AG-3599-01A	70 years, male, stage:i, alive, 366 days	525.4
TCGA-AG-3578-01A	76 years, female, stage:iia, alive, 974 days	525.1
TCGA-G5-6572-01A	56 years, male, white, dead, 1432 days	517.3
TCGA-DY-A1DC-01A	72 years, female, white, stage:iia, dead, 1258 days	515.2
TCGA-AG-A00Y-01A	68 years, male, stage:iia, alive, 700 days	513.8
TCGA-EI-6881-01A	60 years, male, white, stage:iiia, alive, 499 days	510.8
TCGA-EF-5831-01A	72 years, male, white, stage:iia, alive, 127 days	510.0
TCGA-DC-6156-01A	62 years, male, white, stage:iva, alive, 943 days	507.7
TCGA-AF-2687-01A	57 years, male, white, stage:iiic, alive, 1427 days	506.5
TCGA-EI-6507-01A	60 years, male, white, stage:iia, alive, 607 days	504.8
TCGA-F5-6811-01A	72 years, female, white, stage:iia, alive, 979 days	495.3
TCGA-G5-6641-01A	67 years, male, white, stage:iiia, alive, 804 days	484.0
TCGA-DY-A1DE-01A	56 years, female, white, stage:iia, alive, 3932 days	483.3
TCGA-CI-6622-01A	74 years, male, white, stage:iib, alive, 1362 days	476.3
TCGA-AH-6549-01A	66 years, male, white, alive, 532 days	474.1
TCGA-AG-A02N-01A	67 years, male, stage:ii, alive, 1885 days	471.2
TCGA-AH-6547-01A	79 years, female, white, dead, 76 days	451.9
TCGA-CI-6621-01A	63 years, male, white, stage:iiib, alive, 419 days	450.4
TCGA-EI-6508-01A	48 years, female, white, stage:iiib, alive, 636 days	448.2
TCGA-AG-A016-01A	55 years, male, stage:iv, alive, 276 days	439.8
TCGA-AG-A036-01A	71 years, male, stage:iii, alive, 3562 days	433.6
TCGA-AG-A026-01A	66 years, male, stage:ii, dead, 59 days	420.3
TCGA-AG-3584-01A	60 years, male, stage:iv, dead, 730 days	420.2
TCGA-DC-4749-01A	57 years, male, white, stage:i, alive, 762 days	413.3
TCGA-EI-6884-01A	71 years, male, white, stage:iiia, alive, 328 days	412.0
TCGA-F5-6702-01A	71 years, male, white, stage:iva, alive, 869 days	405.0
TCGA-DC-6160-01A	68 years, male, white, stage:i, alive, 1339 days	390.1
TCGA-AG-A011-01A	80 years, male, stage:iia, alive, 1126 days	388.4
TCGA-CI-6624-01C	53 years, female, white, stage:i, alive, 1466 days	387.4
TCGA-AG-A00H-01A	75 years, male, stage:iia, alive, 790 days	383.0
TCGA-AG-4021-01A	84 years, female, stage:iv, dead, 121 days	348.0
TCGA-CI-6619-01B	41 years, male, white, stage:iv, alive, 184 days	331.4
TCGA-F5-6812-01A	67 years, male, white, stage:iia, alive, 1110 days	328.7
TCGA-EI-6882-01A	59 years, male, white, stage:iia, alive, 262 days	325.4
TCGA-AG-3731-01A	65 years, male, stage:iv, alive, 1126 days	320.9
TCGA-AG-3727-01A	78 years, female, stage:iii, alive, 30 days	306.6
TCGA-AG-A02X-01A	77 years, male, stage:i, alive, 1247 days	297.7
TCGA-AG-A032-01A	68 years, male, stage:iiib, alive, 1157 days	263.7
TCGA-AG-A002-01A	35 years, male, stage:i, alive, 638 days	217.0
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