Expression of MT-CO2 in pancreatic cancer

PANCREATIC CANCER - Interactive survival scatter plotⁱ

The Survival Scatter plot shows the clinical status (i.e. dead or alive) for all individuals in the patient cohort, based on the same data that underlies the corresponding Kaplan-Meier plots. Patients that are alive at last time for follow-up are shown in blue and patients who have died during the study are shown in red.

The x-axis shows the expression levels (FPKM) of the investigated gene in the tumor tissue at the time of diagnosis. The y-axis shows the follow-up time after diagnosis (years). Both axes are complimented with kernel density curves demonstrating the data density over the axes. The top density plot shows the expression levels (FPKM) distribution among dead (red) and alive patients (blue). The right density plot shows the data density of the survived years of dead patients with high and low expression levels respectively, stratified using the cutoff indicated by the vertical dashed line through the Survival Scatter plot. This cutoff is automatically defined based on the FPKM cutoff that minimizes the p-score. The cutoff can be changed by dragging the vertical line or by entering a cutoff value in the square labeled "Current cut-off".

Under the Survival Scatter plot the p-score landscape (black curve; left axis) is shown together with dead median separation (red curve; right axis). Dead median separation is the difference in median mRNA expression between patients who have died with high and low expression, respectively. It is calculated as follows: median FPKM expression of dead patients with high expression - median FPKM expression of dead patients with low expression. This is intended to aid the user in visually exploring custom cutoffs and the associated p-scores and dead median separation.

Individual patient data is displayed and can be filtered by clicking on one or more of the category buttons on the top of the page. Categories describing expression level and patient information include: high, low, alive, dead, female, male and tumor stages. The scale of the x-axis can be toggled between linear and log-scale by clicking on the "x log" button. Mouse-over function shows TCGA ID, patient information and mRNA expression (FPKM) for each patient.

& Survival analysisⁱ

MT-CO2 is prognostic, high expression is favorable in pancreatic cancer

Stage:

Survival analysis

Current cut offⁱ:
Best expression cut offⁱ: 6741.13
Median expressionⁱ: N/A
Median follow up timeⁱ: N/A
P scoreⁱ N/A
5-year survival highⁱ N/A
5-year survival lowⁱ N/A

TCGA RNA samplesⁱ

Average FPKM

7362.1

Number of samples

176

Samples

Sample	Description	FPKM
TCGA-3A-A9IV-01A	59 years, female, white, stage:ib, alive, 1103 days	25072.8
TCGA-RB-A7B8-01A	81 years, female, white, stage:iib, dead, 466 days	21327.3
TCGA-HV-A7OP-01A	72 years, male, asian, stage:iib, alive, 978 days	21107.0
TCGA-3A-A9IN-01A	62 years, female, white, stage:ib, alive, 2084 days	18442.8
TCGA-FB-AAPU-01A	41 years, female, asian, stage:iia, dead, 381 days	18441.3
TCGA-FB-AAPP-01A	71 years, male, white, stage:iib, dead, 485 days	17841.9
TCGA-2L-AAQM-01A	52 years, male, white, stage:iib, alive, 1383 days	17488.6
TCGA-FB-AAQ1-01A	49 years, male, white, stage:iib, dead, 123 days	16614.6
TCGA-HZ-A9TJ-01A	70 years, male, white, stage:iv, alive, 603 days	16460.6
TCGA-H8-A6C1-01A	53 years, male, white, stage:iia, alive, 671 days	16185.8
TCGA-LB-A7SX-01A	74 years, female, black or african american, stage:iib, dead, 393 days	15637.9
TCGA-FB-AAQ3-01A	65 years, female, white, stage:iib, dead, 31 days	15480.5
TCGA-2J-AABH-01A	61 years, male, white, stage:iia, alive, 1287 days	15394.4
TCGA-FB-AAPY-01A	71 years, male, white, stage:iib, dead, 1059 days	15029.7
TCGA-F2-A8YN-01A	76 years, male, white, stage:iia, alive, 517 days	14737.1
TCGA-3A-A9IO-01A	56 years, male, white, alive, 1942 days	14636.4
TCGA-2J-AABK-01A	71 years, male, white, stage:iib, alive, 484 days	14375.6
TCGA-HZ-A8P1-01A	81 years, male, white, stage:ib, alive, 7 days	14054.1
TCGA-2L-AAQJ-01A	49 years, female, white, stage:iii, dead, 394 days	13660.6
TCGA-FB-AAQ2-01A	81 years, female, white, stage:iib, dead, 153 days	12995.6
TCGA-US-A776-01A	61 years, male, white, stage:iia, alive, 1216 days	12842.2
TCGA-3A-A9IL-01A	39 years, female, white, stage:i, alive, 2741 days	12835.3
TCGA-HV-AA8X-01A	75 years, female, asian, stage:iib, dead, 532 days	12248.6
TCGA-HZ-7289-01A	77 years, male, white, stage:iib, dead, 661 days	12226.4
TCGA-F2-A44H-01A	65 years, male, white, stage:iia, alive, 586 days	11978.9
TCGA-HV-A5A5-01A	61 years, female, asian, stage:iib, alive, 289 days	11957.5
TCGA-HV-A5A6-01A	65 years, female, asian, stage:iib, dead, 2036 days	11671.4
TCGA-IB-A5SP-01A	77 years, male, white, stage:iia, alive, 482 days	11621.2
TCGA-OE-A75W-01A	75 years, male, white, stage:iia, dead, 267 days	11493.2
TCGA-3A-A9IJ-01A	65 years, male, white, stage:ib, alive, 1854 days	11430.5
TCGA-Q3-AA2A-01A	64 years, female, white, stage:ib, alive, 95 days	11316.7
TCGA-2J-AABT-01A	72 years, female, white, stage:iib, alive, 319 days	10412.6
TCGA-3A-A9IS-01A	67 years, male, white, stage:ib, alive, 998 days	10173.9
TCGA-3E-AAAY-01A	67 years, male, white, stage:iib, alive, 2285 days	10167.1
TCGA-3A-A9I9-01A	67 years, male, white, stage:iia, dead, 634 days	9949.1
TCGA-US-A779-01A	54 years, female, white, stage:iib, dead, 511 days	9787.7
TCGA-3A-A9I7-01A	45 years, male, black or african american, stage:iib, alive, 1323 days	9685.8
TCGA-2J-AAB4-01A	48 years, male, white, stage:iib, alive, 729 days	9453.1
TCGA-S4-A8RM-01A	67 years, male, white, stage:iib, alive, 737 days	9353.6
TCGA-3A-A9I5-01A	58 years, male, white, alive, 1794 days	9322.3
TCGA-IB-AAUO-01A	64 years, female, white, stage:iib, dead, 239 days	9275.7
TCGA-HV-AA8V-01A	50 years, male, asian, stage:iib, alive, 920 days	9139.1
TCGA-US-A77E-01A	73 years, male, white, stage:iib, dead, 430 days	8912.2
TCGA-IB-7649-01A	73 years, female, stage:iib, dead, 467 days	8831.9
TCGA-HZ-A77P-01A	77 years, male, white, stage:iib, alive, 330 days	8800.5
TCGA-FB-AAQ0-01A	68 years, male, white, stage:iia, dead, 473 days	8729.9
TCGA-M8-A5N4-01A	48 years, female, stage:iia, alive, 584 days	8728.2
TCGA-XD-AAUI-01A	50 years, female, white, stage:iib, dead, 366 days	8633.9
TCGA-HZ-A4BK-01A	72 years, male, white, stage:iib, alive, 657 days	8531.7
TCGA-HZ-8637-01A	76 years, female, white, stage:iib, dead, 517 days	8436.4
TCGA-3A-A9J0-01A	75 years, male, white, stage:iib, alive, 743 days	8415.0
TCGA-2L-AAQL-01A	82 years, male, white, stage:iib, dead, 292 days	8398.2
TCGA-Q3-A5QY-01A	58 years, male, white, stage:iib, alive, 416 days	8318.0
TCGA-FB-AAQ6-01A	85 years, male, white, stage:ia, dead, 244 days	8241.0
TCGA-HV-A5A4-01A	72 years, female, asian, stage:iia, alive, 232 days	8094.4
TCGA-HZ-8638-01A	84 years, female, white, stage:ia, dead, 151 days	8011.8
TCGA-HZ-A49H-01A	68 years, female, white, stage:iib, alive, 491 days	7990.4
TCGA-HV-A7OL-01A	70 years, male, asian, stage:iia, alive, 252 days	7978.3
TCGA-RL-AAAS-01A	60 years, female, white, stage:ib, alive, 9 days	7928.9
TCGA-F2-A44G-01A	79 years, female, white, stage:iib, dead, 233 days	7828.1
TCGA-2J-AABE-01A	73 years, male, white, stage:iia, alive, 676 days	7798.9
TCGA-2J-AAB8-01A	71 years, male, white, stage:iib, alive, 80 days	7703.7
TCGA-2J-AABF-01A	73 years, male, white, stage:iib, dead, 691 days	7648.9
TCGA-HZ-8519-01A	73 years, male, white, stage:ia, alive, 454 days	7611.1
TCGA-XN-A8T5-01A	53 years, female, white, stage:ib, alive, 720 days	7583.7
TCGA-FB-AAPQ-01A	65 years, male, white, stage:iib, dead, 1130 days	7562.8
TCGA-IB-A7M4-01A	81 years, male, white, stage:iib, alive, 483 days	7407.6
TCGA-2J-AABO-01A	43 years, male, white, stage:iib, alive, 440 days	7269.8
TCGA-2J-AAB1-01A	65 years, male, white, stage:iib, dead, 66 days	7239.7
TCGA-IB-AAUU-01A	35 years, male, white, stage:iib, alive, 245 days	7098.1
TCGA-FB-AAPZ-01A	54 years, male, white, stage:iib, alive, 716 days	6997.1
TCGA-FB-A7DR-01A	48 years, male, asian, stage:iia, dead, 353 days	6963.1
TCGA-IB-A5SO-01A	71 years, male, white, stage:iib, dead, 365 days	6934.3
TCGA-2J-AABA-01A	55 years, male, white, stage:iib, dead, 607 days	6894.9
TCGA-Z5-AAPL-01A	74 years, female, white, stage:iia, alive, 467 days	6892.4
TCGA-XD-AAUH-01A	57 years, female, white, stage:iib, alive, 395 days	6832.6
TCGA-3E-AAAZ-01A	71 years, male, white, stage:iia, dead, 2182 days	6759.5
TCGA-3A-A9IH-01A	66 years, female, white, stage:ia, alive, 1021 days	6748.6
TCGA-HZ-A77O-01A	77 years, female, white, stage:iib, dead, 160 days	6733.7
TCGA-PZ-A5RE-01A	44 years, female, white, stage:iib, dead, 470 days	6693.5
TCGA-IB-AAUQ-01A	50 years, male, white, stage:iib, dead, 183 days	6671.8
TCGA-3A-A9IR-01A	64 years, female, white, stage:ib, alive, 1542 days	6660.2
TCGA-IB-AAUR-01A	67 years, male, white, stage:iib, alive, 338 days	6467.5
TCGA-FB-A5VM-01A	74 years, male, white, stage:ib, dead, 498 days	6402.6
TCGA-2L-AAQI-01A	66 years, male, white, stage:iib, dead, 103 days	6367.0
TCGA-IB-7645-01A	44 years, female, stage:iib, dead, 1502 days	6279.4
TCGA-FB-A78T-01A	71 years, female, white, stage:iib, dead, 375 days	6221.0
TCGA-2L-AAQE-01A	56 years, male, white, stage:iib, dead, 684 days	6174.0
TCGA-YH-A8SY-01A	73 years, female, white, alive, 388 days	6132.6
TCGA-L1-A7W4-01A	48 years, female, white, stage:iib, dead, 278 days	6112.6
TCGA-US-A77G-01A	64 years, male, white, stage:iib, dead, 12 days	6031.3
TCGA-HV-A5A3-01A	50 years, male, asian, stage:iia, dead, 128 days	5936.4
TCGA-XN-A8T3-01A	67 years, male, white, stage:ib, alive, 951 days	5867.5
TCGA-2J-AABR-01A	60 years, female, white, stage:iia, alive, 438 days	5843.3
TCGA-3A-A9IX-01A	40 years, male, white, stage:ia, alive, 1037 days	5840.2
TCGA-2J-AABU-01A	56 years, male, white, stage:iib, dead, 277 days	5780.8
TCGA-3A-A9IZ-01A	47 years, male, white, stage:iib, dead, 308 days	5759.8
TCGA-US-A77J-01A	81 years, female, white, stage:iib, dead, 568 days	5725.4
TCGA-FB-A4P5-01A	69 years, female, white, stage:iib, dead, 179 days	5708.7
TCGA-LB-A8F3-01A	64 years, female, black or african american, stage:iia, alive, 379 days	5680.7
TCGA-HZ-8317-01A	69 years, female, white, stage:iib, dead, 378 days	5679.2
TCGA-HZ-A49I-01A	77 years, male, white, stage:iib, dead, 308 days	5678.1
TCGA-IB-AAUS-01A	84 years, female, white, stage:iib, alive, 225 days	5536.1
TCGA-YY-A8LH-01A	61 years, female, white, stage:iib, alive, 2016 days	5525.4
TCGA-IB-A6UG-01A	65 years, male, white, stage:iib, dead, 41 days	5522.6
TCGA-H6-A45N-01A	88 years, female, white, stage:iib, dead, 421 days	5505.9
TCGA-IB-7651-01A	64 years, female, white, stage:iib, dead, 603 days	5495.1
TCGA-S4-A8RP-01A	77 years, female, white, stage:iib, dead, 702 days	5446.5
TCGA-US-A774-01A	76 years, female, white, stage:iib, dead, 695 days	5438.4
TCGA-FB-AAPS-01A	62 years, female, white, stage:iib, alive, 228 days	5435.5
TCGA-S4-A8RO-01A	75 years, female, white, stage:iib, alive, 525 days	5433.4
TCGA-IB-AAUM-01A	76 years, male, white, stage:iib, alive, 8 days	5408.5
TCGA-F2-A7TX-01A	77 years, male, white, stage:iib, dead, 95 days	5403.7
TCGA-HZ-8001-01A	69 years, male, white, stage:iii, alive, 706 days	5275.5
TCGA-2J-AABV-01A	74 years, male, white, stage:iib, dead, 652 days	5243.4
TCGA-2J-AABI-01A	55 years, female, white, stage:iia, alive, 969 days	5207.9
TCGA-IB-AAUW-01A	63 years, female, white, stage:iib, dead, 230 days	5100.7
TCGA-HZ-A49G-01A	58 years, female, white, stage:iib, alive, 660 days	5084.9
TCGA-F2-6880-01A	70 years, male, white, stage:iib, alive, 289 days	5008.9
TCGA-XD-AAUG-01A	66 years, female, white, stage:iv, alive, 420 days	4976.8
TCGA-HZ-7924-01A	60 years, female, white, stage:iia, alive, 840 days	4826.7
TCGA-FB-A545-01A	72 years, female, white, stage:iib, dead, 732 days	4764.5
TCGA-2J-AAB6-01A	75 years, male, white, stage:iia, dead, 293 days	4763.4
TCGA-HZ-A77Q-01A	55 years, female, white, stage:iib, alive, 33 days	4733.2
TCGA-IB-8126-01A	80 years, female, white, stage:iii, alive, 462 days	4700.0
TCGA-IB-7889-01A	86 years, female, white, stage:iib, dead, 481 days	4662.1
TCGA-IB-AAUN-01A	74 years, female, white, stage:ib, dead, 144 days	4565.0
TCGA-HZ-8315-01A	54 years, female, white, stage:iia, dead, 299 days	4557.5
TCGA-IB-7652-01A	49 years, female, asian, stage:iib, alive, 1116 days	4557.2
TCGA-IB-7644-01A	65 years, female, white, stage:iv, dead, 394 days	4489.1
TCGA-IB-A5ST-01A	64 years, female, white, stage:iib, alive, 635 days	4486.2
TCGA-2J-AAB9-01A	71 years, female, white, stage:iib, dead, 627 days	4475.6
TCGA-IB-A6UF-01A	63 years, male, white, stage:iib, alive, 666 days	4467.1
TCGA-IB-A5SQ-01A	56 years, female, white, stage:ib, dead, 219 days	4432.0
TCGA-3A-A9IC-01A	61 years, female, white, stage:iib, dead, 738 days	4398.2
TCGA-3A-A9IB-01A	69 years, female, white, stage:iib, dead, 224 days	4376.7
TCGA-3A-A9IU-01A	65 years, male, white, stage:iib, dead, 458 days	4339.6
TCGA-IB-AAUV-01A	49 years, male, white, stage:iib, alive, 404 days	4286.4
TCGA-RB-AA9M-01A	43 years, male, white, stage:iib, alive, 286 days	4267.2
TCGA-LB-A9Q5-01A	63 years, female, white, stage:iib, dead, 313 days	4266.4
TCGA-FB-A4P6-01A	54 years, male, white, stage:iib, alive, 767 days	4164.1
TCGA-IB-7885-01A	78 years, female, white, stage:iib, alive, 1257 days	4060.8
TCGA-IB-AAUT-01A	65 years, male, white, stage:iib, alive, 287 days	3975.3
TCGA-HZ-A4BH-01A	75 years, male, white, stage:iib, alive, 194 days	3963.2
TCGA-IB-AAUP-01A	68 years, male, white, stage:iib, alive, 431 days	3958.9
TCGA-2J-AABP-01A	58 years, female, white, stage:iib, alive, 463 days	3930.8
TCGA-XD-AAUL-01A	56 years, male, white, stage:iia, alive, 498 days	3924.3
TCGA-2L-AAQA-01A	76 years, male, white, stage:iib, dead, 143 days	3917.9
TCGA-IB-7646-01A	60 years, male, white, stage:iib, dead, 145 days	3857.2
TCGA-IB-7887-01A	62 years, female, white, stage:iib, dead, 110 days	3843.1
TCGA-YB-A89D-01A	59 years, male, white, stage:iib, alive, 350 days	3841.2
TCGA-IB-A7LX-01A	57 years, male, white, stage:iib, dead, 250 days	3811.3
TCGA-HZ-7923-01A	65 years, male, white, stage:iia, alive, 314 days	3634.3
TCGA-IB-7897-01A	54 years, female, white, stage:iib, dead, 486 days	3472.3
TCGA-HZ-7926-01A	57 years, male, black or african american, stage:iib, dead, 518 days	3361.2
TCGA-IB-7654-01A	80 years, male, white, stage:iib, dead, 476 days	3261.6
TCGA-HZ-8636-01A	58 years, female, white, stage:iv, dead, 545 days	3195.1
TCGA-IB-7888-01A	66 years, female, black or african american, stage:iia, dead, 1332 days	3109.8
TCGA-HZ-7920-01A	71 years, male, white, stage:ib, dead, 236 days	3109.2
TCGA-HZ-7925-01A	66 years, male, white, stage:iib, dead, 614 days	3039.3
TCGA-HZ-8002-01A	61 years, male, white, stage:iib, dead, 366 days	2810.6
TCGA-F2-7276-01A	64 years, male, white, stage:iib, dead, 216 days	2754.7
TCGA-IB-A5SS-01A	64 years, female, white, stage:iib, dead, 460 days	2753.5
TCGA-H6-8124-01A	56 years, female, white, stage:iib, alive, 392 days	2747.2
TCGA-IB-8127-01A	59 years, male, white, stage:iib, alive, 522 days	2678.4
TCGA-IB-7890-01A	73 years, male, stage:ib, dead, 598 days	2321.5
TCGA-HZ-7919-01A	52 years, female, white, stage:iib, dead, 593 days	2319.3
TCGA-IB-7891-01A	49 years, female, white, stage:iib, dead, 913 days	2275.3
TCGA-HZ-8005-01A	81 years, male, white, stage:iib, dead, 120 days	2236.5
TCGA-F2-6879-01A	57 years, male, white, stage:iib, dead, 334 days	2114.4
TCGA-HZ-8003-01A	65 years, female, white, stage:iib, dead, 596 days	2019.8
TCGA-IB-7893-01A	64 years, male, white, stage:iia, dead, 117 days	1957.1
TCGA-HZ-7918-01A	72 years, male, white, stage:iib, alive, 969 days	1887.5
TCGA-F2-7273-01A	54 years, male, black or african american, stage:iib, dead, 592 days	1771.7
TCGA-HZ-7922-01A	61 years, female, white, stage:iib, alive, 4 days	1371.5
TCGA-IB-7886-01A	80 years, male, white, stage:iib, dead, 123 days	1293.9
Show allShow less

PANCREATIC CANCER - Protein expressionⁱ A mouse-over function shows sample information and annotation data. Click on an image to view it in a full screen mode. Samples can be filtered based on level of antibody staining by selecting one or several of the following categories: high, medium, low and not detected. The assay and annotation is described here. Note that samples used for immunohistochemistry by the Human Protein Atlas do not correspond to samples in the TCGA dataset.

Antibody stainingⁱ Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high. This score is based on the staining intensity and fraction of stained cells. Read more	Antibody HPA051505	Antibody HPA054758	Antibody CAB016243
Staining
High
Medium
Low
Not detected
Intensity
Strong
Moderate
Weak
Negative
Quantity
>75%
75%-25%
<25%
None
Location
Nuclear
Cytoplasmic/membranous
Cytoplasmic/membranous,nuclear
None
Click images for details