Expression of MT-ND2 in melanoma - The Human Protein Atlas

MELANOMA - Interactive survival scatter plotⁱ

The Survival Scatter plot shows the clinical status (i.e. dead or alive) for all individuals in the patient cohort, based on the same data that underlies the corresponding Kaplan-Meier plots. Patients that are alive at last time for follow-up are shown in blue and patients who have died during the study are shown in red.

The x-axis shows the expression levels (FPKM) of the investigated gene in the tumor tissue at the time of diagnosis. The y-axis shows the follow-up time after diagnosis (years). Both axes are complimented with kernel density curves demonstrating the data density over the axes. The top density plot shows the expression levels (FPKM) distribution among dead (red) and alive patients (blue). The right density plot shows the data density of the survived years of dead patients with high and low expression levels respectively, stratified using the cutoff indicated by the vertical dashed line through the Survival Scatter plot. This cutoff is automatically defined based on the FPKM cutoff that minimizes the p-score. The cutoff can be changed by dragging the vertical line or by entering a cutoff value in the square labeled "Current cut-off".

Under the Survival Scatter plot the p-score landscape (black curve; left axis) is shown together with dead median separation (red curve; right axis). Dead median separation is the difference in median mRNA expression between patients who have died with high and low expression, respectively. It is calculated as follows: median FPKM expression of dead patients with high expression - median FPKM expression of dead patients with low expression. This is intended to aid the user in visually exploring custom cutoffs and the associated p-scores and dead median separation.

Individual patient data is displayed and can be filtered by clicking on one or more of the category buttons on the top of the page. Categories describing expression level and patient information include: high, low, alive, dead, female, male and tumor stages. The scale of the x-axis can be toggled between linear and log-scale by clicking on the "x log" button. Mouse-over function shows TCGA ID, patient information and mRNA expression (FPKM) for each patient.

& Survival analysisⁱ

MT-ND2 is not prognostic in melanoma

Stage:

Survival analysis

Current cut offⁱ:
Best expression cut offⁱ: 5984.66
Median expressionⁱ: N/A
Median follow up timeⁱ: N/A
P scoreⁱ N/A
3-year survival highⁱ N/A
3-year survival lowⁱ N/A

TCGA RNA samplesⁱ

Average FPKM

5260.4

Number of samples

102

Samples

Sample	Description	FPKM
TCGA-DA-A960-01A	73 years, male, white, stage:iib, alive, 804 days	33156.4
TCGA-EB-A553-01A	62 years, male, white, stage:iic, alive, 226 days	33028.4
TCGA-D3-A5GT-01A	43 years, male, white, stage:iiic, alive, 487 days	21431.7
TCGA-EB-A4OY-01A	65 years, female, white, stage:iiib, alive, 977 days	16142.4
TCGA-EB-A4OZ-01A	42 years, female, white, stage:iiic, alive, 620 days	14103.4
TCGA-GN-A263-01A	24 years, male, white, stage:iv, dead, 467 days	13565.2
TCGA-ER-A194-01A	77 years, male, white, dead, 1354 days	13539.2
TCGA-BF-AAP8-01A	58 years, male, white, stage:iic, alive, 447 days	11923.5
TCGA-FW-A5DX-01A	71 years, male, white, stage:iiic, alive, 640 days	11160.3
TCGA-XV-AAZY-01A	76 years, female, white, stage:iiic, alive, 405 days	10374.6
TCGA-FR-A726-01A	90 years, male, white, stage:iic, dead, 305 days	10263.3
TCGA-FR-A728-01A	54 years, female, white, stage:iiib, alive, 583 days	9882.7
TCGA-EB-A41A-01A	90 years, male, white, stage:iic, alive, 262 days	9717.1
TCGA-EB-A551-01A	78 years, female, white, stage:iiic, alive, 590 days	9240.6
TCGA-BF-A5EQ-01A	63 years, male, white, stage:iic, alive, 323 days	8803.0
TCGA-EB-A85I-01A	66 years, male, white, stage:iic, alive, 362 days	8296.6
TCGA-D9-A4Z3-01A	73 years, female, white, stage:iiic, alive, 505 days	7968.5
TCGA-BF-A5ER-01A	63 years, male, white, stage:iic, alive, 327 days	7450.6
TCGA-BF-A9VF-01A	77 years, male, white, stage:iic, alive, 440 days	7102.6
TCGA-EB-A57M-01A	56 years, male, asian, stage:iiib, dead, 472 days	6896.0
TCGA-BF-A3DL-01A	84 years, female, white, stage:iiib, alive, 769 days	6508.7
TCGA-YG-AA3N-01A	67 years, male, stage:iic, alive, 306 days	6316.5
TCGA-BF-AAOU-01A	73 years, female, white, stage:iic, alive, 476 days	6060.0
TCGA-EB-A3Y6-01A	56 years, female, white, stage:iic, alive, 126 days	5909.3
TCGA-ER-A2NB-01A	57 years, male, white, stage:iiib, dead, 857 days	5814.3
TCGA-EB-A5SF-01A	78 years, female, white, stage:iic, dead, 369 days	5777.2
TCGA-XV-AAZW-01A	62 years, female, white, stage:ii, dead, 393 days	5631.3
TCGA-EB-A82B-01A	58 years, female, asian, stage:iii, alive, 390 days	5478.2
TCGA-EB-A3Y7-01A	86 years, female, white, stage:iiib, dead, 326 days	5445.8
TCGA-D9-A4Z5-01A	68 years, male, white, stage:iib, alive, 218 days	5366.2
TCGA-BF-A5EP-01A	75 years, female, white, stage:iiic, alive, 335 days	5210.7
TCGA-XV-A9W2-01A	81 years, male, white, stage:i, alive, 417 days	5084.1
TCGA-EB-A24D-01A	72 years, male, white, stage:iiib, alive, 645 days	4995.7
TCGA-EB-A6QZ-01A	76 years, female, white, stage:iia, dead, 352 days	4892.6
TCGA-EB-A5UM-01A	48 years, female, white, stage:iic, alive, 779 days	4842.1
TCGA-GN-A4U5-01A	61 years, female, white, stage:ib, alive, 1156 days	4821.0
TCGA-EB-A5FP-01A	65 years, female, white, stage:iv, dead, 454 days	4643.4
TCGA-ER-A2NF-01A	53 years, male, white, stage:iiib, dead, 877 days	4592.9
TCGA-D9-A4Z2-01A	50 years, male, white, stage:iiic, dead, 190 days	4560.7
TCGA-BF-AAP4-01A	61 years, male, white, stage:iic, alive, 335 days	4337.8
TCGA-BF-A1PX-01A	56 years, male, white, stage:iiib, dead, 282 days	4315.4
TCGA-ER-A19K-01A	79 years, female, white, stage:iic, dead, 469 days	4296.2
TCGA-D9-A3Z4-01A	54 years, male, white, stage:iiic, dead, 519 days	4236.6
TCGA-IH-A3EA-01A	61 years, male, white, stage:iic, alive, 524 days	4217.3
TCGA-EB-A6QY-01A	71 years, male, white, stage:iic, alive, 382 days	4200.8
TCGA-GF-A769-01A	39 years, male, white, stage:iic, dead, 1070 days	4172.7
TCGA-EB-A3XB-01A	63 years, male, white, stage:ii, alive, 796 days	4112.8
TCGA-BF-AAP7-01A	76 years, female, white, stage:iic, alive, 318 days	4041.7
TCGA-EB-A3XD-01A	53 years, female, white, stage:iic, alive, 1160 days	3961.3
TCGA-BF-AAOX-01A	83 years, male, white, stage:iic, alive, 444 days	3945.4
TCGA-EB-A299-01A	63 years, male, white, stage:iia, alive, 378 days	3904.6
TCGA-ER-A19T-01A	51 years, male, white, stage:iv, dead, 270 days	3843.5
TCGA-EB-A97M-01A	66 years, male, white, stage:iic, alive, 414 days	3835.1
TCGA-EB-A42Z-01A	49 years, male, asian, stage:iiic, alive, 441 days	3784.8
TCGA-BF-AAP2-01A	62 years, male, white, stage:iib, alive, 405 days	3712.1
TCGA-EB-A3XE-01A	77 years, female, white, stage:iia, alive, 180 days	3656.4
TCGA-GN-A8LN-01A	68 years, male, white, stage:iic, alive, 772 days	3501.9
TCGA-EB-A431-01A	34 years, male, white, stage:iic, alive, 568 days	3478.9
TCGA-BF-A5ES-01A	76 years, female, white, stage:iic, alive, 490 days	3427.3
TCGA-GF-A2C7-01A	48 years, male, white, stage:iic, alive, 21 days	3247.3
TCGA-EB-A1NK-01A	48 years, male, white, stage:iic, alive, 1039 days	3147.7
TCGA-BF-A1PZ-01A	71 years, female, white, stage:iib, alive, 853 days	3130.5
TCGA-EB-A4XL-01A	56 years, female, white, stage:iic, alive, 777 days	3115.2
TCGA-EB-A4IQ-01A	42 years, female, asian, stage:iiib, dead, 636 days	3081.2
TCGA-XV-A9W5-01A	51 years, male, white, stage:i/ii nos, alive, 392 days	2945.1
TCGA-BF-AAP6-01A	55 years, male, white, stage:iii, alive, 325 days	2861.1
TCGA-EB-A85J-01A	66 years, female, white, stage:iib, alive, 360 days	2706.2
TCGA-EB-A4P0-01A	82 years, male, white, stage:iic, dead, 326 days	2694.1
TCGA-EB-A4IS-01A	77 years, male, white, stage:iib, alive, 774 days	2615.4
TCGA-WE-A8K4-01A	85 years, male, white, stage:iib, alive, 614 days	2593.9
TCGA-EB-A44P-01A	58 years, female, white, stage:iic, alive, 741 days	2593.7
TCGA-EB-A3HV-01A	37 years, male, white, stage:iic, alive, 39 days	2565.3
TCGA-HR-A5NC-01A	90 years, female, alive, 1000 days	2499.7
TCGA-EB-A24C-01A	56 years, male, white, alive, 632 days	2492.4
TCGA-ER-A42H-01A	77 years, male, white, dead, 426 days	2492.0
TCGA-BF-A1PU-01A	46 years, female, white, stage:iic, alive, 387 days	2475.4
TCGA-EB-A5VU-01A	56 years, male, asian, stage:iiib, dead, 321 days	2402.8
TCGA-EB-A6R0-01A	58 years, female, white, stage:iic, dead, 608 days	2346.7
TCGA-EB-A41B-01A	76 years, female, white, stage:iic, alive, 291 days	2336.2
TCGA-BF-A5EO-01A	65 years, male, white, stage:iic, alive, 703 days	2221.2
TCGA-EB-A44N-01A	59 years, male, white, stage:iic, dead, 205 days	2182.8
TCGA-XV-AAZV-01A	56 years, female, white, stage:ii, alive, 412 days	2154.9
TCGA-EB-A42Y-01A	73 years, female, asian, stage:iic, dead, 721 days	2042.2
TCGA-BF-A3DJ-01A	36 years, female, white, stage:iiib, alive, 464 days	1949.5
TCGA-GN-A26C-01A	77 years, male, white, stage:iiic, dead, 821 days	1933.8
TCGA-BF-A3DN-01A	81 years, female, white, stage:iiic, alive, 717 days	1822.5
TCGA-EB-A51B-01A	53 years, male, white, stage:iic, alive, 931 days	1812.7
TCGA-EB-A3XC-01A	74 years, male, white, stage:iic, alive, 650 days	1784.9
TCGA-FS-A1ZN-01A	43 years, male, white, stage:iiia, dead, 730 days	1737.4
TCGA-BF-AAP1-01A	86 years, male, white, stage:iic, alive, 409 days	1622.4
TCGA-EB-A82C-01A	70 years, female, asian, stage:iic, alive, 17 days	1583.5
TCGA-EB-A44O-01A	69 years, male, white, stage:iib, alive, 81 days	1551.8
TCGA-EB-A5SE-01A	73 years, male, white, stage:iib, dead, 401 days	1548.1
TCGA-ER-A196-01A	64 years, female, white, stage:iic, alive, 1785 days	1500.3
TCGA-FR-A2OS-01A	49 years, female, white, stage:iic, dead, 368 days	1469.1
TCGA-BF-A1PV-01A	74 years, female, white, stage:iic, alive, 14 days	1453.6
TCGA-XV-A9VZ-01A	90 years, female, white, stage:ii, alive, 11 days	1412.5
TCGA-EB-A550-01A	75 years, female, white, stage:iic, dead, 264 days	1376.6
TCGA-EB-A3XF-01A	57 years, male, white, stage:iic, alive, 278 days	1302.4
TCGA-BF-A1Q0-01A	80 years, male, white, stage:iic, alive, 831 days	1172.3
TCGA-FR-A3R1-01A	69 years, male, white, stage:iic, alive, 685 days	1030.0
TCGA-BF-A3DM-01A	63 years, male, white, stage:iia, alive, 601 days	579.1
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MELANOMA - Protein expressionⁱ

Pending cancer tissue analysis