Expression of MT-ND5 in glioma - The Human Protein Atlas

GLIOMA - Interactive survival scatter plotⁱ

The Survival Scatter plot shows the clinical status (i.e. dead or alive) for all individuals in the patient cohort, based on the same data that underlies the corresponding Kaplan-Meier plots. Patients that are alive at last time for follow-up are shown in blue and patients who have died during the study are shown in red.

The x-axis shows the expression levels (FPKM) of the investigated gene in the tumor tissue at the time of diagnosis. The y-axis shows the follow-up time after diagnosis (years). Both axes are complimented with kernel density curves demonstrating the data density over the axes. The top density plot shows the expression levels (FPKM) distribution among dead (red) and alive patients (blue). The right density plot shows the data density of the survived years of dead patients with high and low expression levels respectively, stratified using the cutoff indicated by the vertical dashed line through the Survival Scatter plot. This cutoff is automatically defined based on the FPKM cutoff that minimizes the p-score. The cutoff can be changed by dragging the vertical line or by entering a cutoff value in the square labeled "Current cut-off".

Under the Survival Scatter plot the p-score landscape (black curve; left axis) is shown together with dead median separation (red curve; right axis). Dead median separation is the difference in median mRNA expression between patients who have died with high and low expression, respectively. It is calculated as follows: median FPKM expression of dead patients with high expression - median FPKM expression of dead patients with low expression. This is intended to aid the user in visually exploring custom cutoffs and the associated p-scores and dead median separation.

Individual patient data is displayed and can be filtered by clicking on one or more of the category buttons on the top of the page. Categories describing expression level and patient information include: high, low, alive, dead, female, male and tumor stages. The scale of the x-axis can be toggled between linear and log-scale by clicking on the "x log" button. Mouse-over function shows TCGA ID, patient information and mRNA expression (FPKM) for each patient.

& Survival analysisⁱ

MT-ND5 is not prognostic in glioma

Stage:

Survival analysis

Current cut offⁱ:
Best expression cut offⁱ: 1631.93
Median expressionⁱ: N/A
Median follow up timeⁱ: N/A
P scoreⁱ N/A
3-year survival highⁱ N/A
3-year survival lowⁱ N/A

TCGA RNA samplesⁱ

Average FPKM

1457.5

Number of samples

153

Samples

Sample	Description	FPKM
TCGA-26-1442-01A	43 years, male, white, alive, 953 days	5645.9
TCGA-19-2620-01A	70 years, male, white, dead, 148 days	4229.5
TCGA-27-1835-01A	53 years, female, white, dead, 648 days	4032.3
TCGA-26-5136-01B	78 years, female, white, dead, 577 days	3783.0
TCGA-06-0141-01A	62 years, male, white, dead, 313 days	3698.6
TCGA-06-2561-01A	53 years, female, white, dead, 537 days	3436.9
TCGA-27-2519-01A	48 years, male, white, dead, 550 days	3260.8
TCGA-06-0882-01A	30 years, male, white, dead, 632 days	3256.2
TCGA-06-1804-01A	81 years, female, white, dead, 414 days	3103.3
TCGA-26-5134-01A	74 years, male, white, alive, 167 days	2994.1
TCGA-19-2625-01A	76 years, female, white, dead, 124 days	2897.6
TCGA-19-1787-01B	49 years, male, white, dead, 385 days	2889.5
TCGA-06-2557-01A	76 years, male, black or african american, dead, 33 days	2469.1
TCGA-14-0871-01A	75 years, female, white, dead, 880 days	2405.4
TCGA-06-0187-01A	69 years, male, white, dead, 828 days	2395.8
TCGA-06-0649-01B	73 years, female, black or african american, dead, 64 days	2367.1
TCGA-06-0132-01A	49 years, male, white, dead, 771 days	2323.4
TCGA-06-0210-01A	72 years, female, white, dead, 225 days	2307.4
TCGA-41-4097-01A	63 years, female, white, dead, 6 days	2304.9
TCGA-02-0047-01A	78 years, male, white, dead, 448 days	2302.5
TCGA-27-1837-01A	36 years, male, white, dead, 427 days	2245.1
TCGA-06-0168-01A	59 years, female, white, dead, 598 days	2234.2
TCGA-27-1830-01A	57 years, male, white, dead, 154 days	2224.5
TCGA-06-0743-01A	69 years, male, white, dead, 803 days	2174.5
TCGA-06-2570-01A	21 years, female, white, alive, 958 days	2135.0
TCGA-32-2615-01A	62 years, male, white, dead, 485 days	2118.9
TCGA-19-1390-01A	63 years, female, white, dead, 772 days	2104.8
TCGA-16-1045-01B	49 years, female, white, dead, 883 days	2099.9
TCGA-28-1753-01A	53 years, male, white, alive, 37 days	2095.7
TCGA-06-0156-01A	57 years, male, white, dead, 178 days	2065.2
TCGA-06-2562-01A	81 years, male, white, dead, 382 days	1997.7
TCGA-06-0750-01A	43 years, male, white, dead, 28 days	1945.9
TCGA-15-0742-01A	65 years, male, white, dead, 419 days	1934.1
TCGA-32-1982-01A	76 years, female, white, dead, 142 days	1920.0
TCGA-06-0744-01A	67 years, male, white, dead, 1426 days	1909.0
TCGA-12-0619-01A	60 years, male, white, dead, 1062 days	1883.6
TCGA-06-2564-01A	50 years, male, white, alive, 181 days	1880.8
TCGA-14-0789-01A	54 years, male, white, dead, 342 days	1870.2
TCGA-28-2499-01A	59 years, male, white, dead, 95 days	1867.3
TCGA-06-0130-01A	54 years, male, white, dead, 394 days	1844.8
TCGA-06-2558-01A	75 years, female, white, dead, 380 days	1836.8
TCGA-32-1980-01A	72 years, male, white, dead, 36 days	1816.5
TCGA-06-0129-01A	30 years, male, asian, dead, 1024 days	1812.0
TCGA-14-0781-01B	49 years, male, black or african american, dead, 29 days	1783.3
TCGA-41-2571-01A	89 years, male, white, dead, 26 days	1760.3
TCGA-28-1747-01C	44 years, male, white, dead, 77 days	1756.9
TCGA-06-5411-01A	51 years, male, white, dead, 254 days	1748.5
TCGA-76-4929-01A	76 years, female, white, dead, 111 days	1727.0
TCGA-06-0125-01A	63 years, female, white, dead, 1448 days	1726.1
TCGA-32-2638-01A	67 years, male, white, dead, 766 days	1725.9
TCGA-06-2565-01A	59 years, male, asian, dead, 506 days	1719.2
TCGA-15-1444-01A	21 years, male, white, dead, 1537 days	1712.2
TCGA-06-0646-01A	61 years, male, white, dead, 175 days	1688.7
TCGA-76-4926-01B	68 years, male, white, dead, 138 days	1685.8
TCGA-27-1834-01A	56 years, male, white, dead, 1233 days	1658.7
TCGA-19-4065-01A	36 years, male, white, alive, 214 days	1647.7
TCGA-32-2634-01A	82 years, male, white, alive, 693 days	1637.9
TCGA-32-1970-01A	59 years, male, white, dead, 468 days	1626.0
TCGA-06-0745-01A	59 years, male, white, dead, 239 days	1599.9
TCGA-16-0846-01A	85 years, male, white, dead, 119 days	1554.8
TCGA-06-0139-01A	40 years, male, white, dead, 362 days	1550.8
TCGA-27-1832-01A	59 years, female, white, dead, 300 days	1545.3
TCGA-26-5139-01A	65 years, female, white, alive, 48 days	1533.2
TCGA-32-2616-01A	48 years, female, white, dead, 224 days	1531.9
TCGA-06-0749-01A	50 years, male, black or african american, dead, 82 days	1516.9
TCGA-14-0790-01B	64 years, female, white, dead, 419 days	1502.8
TCGA-06-0157-01A	63 years, female, white, dead, 97 days	1501.6
TCGA-26-5135-01A	72 years, female, white, dead, 270 days	1498.0
TCGA-06-2567-01A	65 years, male, white, dead, 133 days	1479.8
TCGA-19-2619-01A	55 years, female, black or african american, alive, 294 days	1401.1
TCGA-27-2528-01A	62 years, male, white, dead, 480 days	1387.2
TCGA-06-0878-01A	74 years, male, white, alive, 218 days	1339.7
TCGA-76-4925-01A	76 years, male, white, dead, 146 days	1337.6
TCGA-06-0645-01A	56 years, female, white, dead, 175 days	1324.5
TCGA-06-0219-01A	67 years, male, white, dead, 22 days	1316.9
TCGA-06-0686-01A	53 years, male, white, dead, 432 days	1303.8
TCGA-06-5416-01A	23 years, female, white, alive, 204 days	1291.4
TCGA-08-0386-01A	74 years, male, white, dead, 548 days	1283.8
TCGA-41-2572-01A	67 years, male, white, dead, 406 days	1274.0
TCGA-06-0238-01A	46 years, male, white, dead, 405 days	1271.0
TCGA-19-2624-01A	51 years, male, white, dead, 5 days	1268.2
TCGA-32-2632-01A	80 years, male, white, dead, 269 days	1219.8
TCGA-06-0138-01A	43 years, male, white, dead, 737 days	1211.9
TCGA-06-0747-01A	53 years, male, white, dead, 82 days	1208.7
TCGA-32-4213-01A	47 years, female, white, alive, 604 days	1195.2
TCGA-14-1034-01A	60 years, female, dead, 485 days	1190.1
TCGA-14-1825-01A	70 years, male, white, dead, 232 days	1168.2
TCGA-14-0787-01A	69 years, male, asian, dead, 68 days	1156.9
TCGA-06-0184-01A	63 years, male, white, dead, 2126 days	1139.1
TCGA-26-5132-01A	74 years, male, white, alive, 286 days	1128.3
TCGA-12-0821-01A	62 years, male, white, dead, 323 days	1127.4
TCGA-06-2563-01A	72 years, female, white, alive, 932 days	1119.0
TCGA-06-5414-01A	61 years, male, white, alive, 273 days	1091.4
TCGA-41-3915-01A	48 years, male, white, dead, 360 days	1074.8
TCGA-12-0616-01A	36 years, female, white, dead, 448 days	1069.4
TCGA-28-2514-01A	45 years, male, asian, alive, 160 days	1029.5
TCGA-06-2559-01A	83 years, male, white, dead, 150 days	1020.7
TCGA-06-0158-01A	73 years, male, white, dead, 329 days	1013.6
TCGA-06-0178-01A	39 years, male, white, dead, 2681 days	1012.6
TCGA-06-5418-01A	75 years, female, white, dead, 83 days	1008.3
TCGA-06-0190-01A	62 years, male, white, dead, 317 days	1001.3
TCGA-02-2483-01A	43 years, male, asian, alive, 466 days	995.6
TCGA-28-2513-01A	69 years, female, white, alive, 222 days	994.3
TCGA-26-5133-01A	59 years, male, white, alive, 452 days	979.3
TCGA-76-4927-01A	58 years, male, white, dead, 535 days	969.9
TCGA-14-1823-01A	58 years, female, white, dead, 543 days	966.7
TCGA-27-2521-01A	34 years, male, white, dead, 510 days	951.7
TCGA-14-2554-01A	52 years, female, white, dead, 532 days	919.5
TCGA-28-5216-01A	52 years, male, white, alive, 415 days	909.7
TCGA-06-5858-01A	45 years, female, white, alive, 187 days	904.8
TCGA-28-5218-01A	63 years, male, white, dead, 157 days	892.8
TCGA-14-0817-01A	69 years, female, white, dead, 164 days	891.4
TCGA-06-5412-01A	78 years, female, white, dead, 138 days	890.9
TCGA-28-5207-01A	71 years, male, white, dead, 343 days	890.1
TCGA-06-5417-01A	45 years, female, white, alive, 155 days	840.5
TCGA-28-5220-01A	67 years, male, white, dead, 388 days	834.2
TCGA-76-4928-01B	85 years, female, white, dead, 94 days	832.4
TCGA-19-2629-01A	60 years, male, white, dead, 737 days	819.4
TCGA-06-5410-01A	72 years, female, white, dead, 108 days	793.9
TCGA-28-5215-01A	62 years, female, white, dead, 335 days	784.8
TCGA-76-4931-01A	70 years, female, white, dead, 279 days	782.7
TCGA-41-5651-01A	59 years, female, black or african american, dead, 460 days	779.1
TCGA-06-2569-01A	24 years, female, black or african american, alive, 13 days	777.7
TCGA-27-2524-01A	56 years, male, white, dead, 231 days	776.5
TCGA-06-0644-01A	71 years, male, black or african american, dead, 384 days	768.0
TCGA-12-0618-01A	49 years, male, white, dead, 395 days	756.2
TCGA-06-0211-01B	47 years, male, white, dead, 360 days	739.2
TCGA-76-4932-01A	50 years, female, white, dead, 1458 days	729.6
TCGA-28-2509-01A	77 years, female, white, alive, 145 days	665.8
TCGA-27-2526-01A	79 years, female, white, dead, 87 days	656.5
TCGA-02-2485-01A	53 years, male, black or african american, alive, 470 days	638.2
TCGA-02-0055-01A	62 years, female, white, dead, 76 days	616.4
TCGA-28-5209-01A	66 years, female, white, alive, 77 days	611.5
TCGA-19-5960-01A	56 years, male, white, dead, 455 days	608.8
TCGA-12-1597-01B	62 years, female, white, dead, 675 days	601.0
TCGA-14-1829-01A	57 years, male, black or african american, alive, 218 days	594.9
TCGA-06-5413-01A	67 years, male, white, alive, 268 days	548.6
TCGA-06-5856-01A	58 years, male, white, dead, 114 days	535.5
TCGA-06-5408-01A	54 years, female, white, dead, 357 days	512.9
TCGA-06-0174-01A	54 years, male, white, dead, 98 days	490.4
TCGA-27-2523-01A	63 years, male, white, dead, 489 days	443.5
TCGA-06-5859-01A	63 years, male, white, alive, 139 days	415.4
TCGA-12-3653-01A	34 years, female, white, dead, 442 days	407.4
TCGA-28-5204-01A	72 years, male, white, dead, 454 days	380.6
TCGA-12-5299-01A	56 years, female, white, dead, 98 days	358.2
TCGA-12-3650-01A	46 years, male, white, dead, 333 days	328.5
TCGA-12-3652-01A	60 years, male, white, dead, 1062 days	311.2
TCGA-27-1831-01A	66 years, male, white, dead, 505 days	306.1
TCGA-02-2486-01A	64 years, male, white, dead, 618 days	297.0
TCGA-28-5208-01A	52 years, male, white, dead, 544 days	293.9
TCGA-32-5222-01A	66 years, male, white, dead, 585 days	256.1
TCGA-28-5213-01A	72 years, male, white, alive, 951 days	220.0
TCGA-12-5295-01A	60 years, female, white, dead, 454 days	206.5
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GLIOMA - Protein expressionⁱ

Pending cancer tissue analysis