Expression of MT-ND4 in colorectal cancer

RECTUM ADENOCARCINOMA (READ) - Interactive survival scatter plotⁱ

The Survival Scatter plot shows the clinical status (i.e. dead or alive) for all individuals in the patient cohort, based on the same data that underlies the corresponding Kaplan-Meier plots. Patients that are alive at last time for follow-up are shown in blue and patients who have died during the study are shown in red.

The x-axis shows the expression levels (FPKM) of the investigated gene in the tumor tissue at the time of diagnosis. The y-axis shows the follow-up time after diagnosis (years). Both axes are complimented with kernel density curves demonstrating the data density over the axes. The top density plot shows the expression levels (FPKM) distribution among dead (red) and alive patients (blue). The right density plot shows the data density of the survived years of dead patients with high and low expression levels respectively, stratified using the cutoff indicated by the vertical dashed line through the Survival Scatter plot. This cutoff is automatically defined based on the FPKM cutoff that minimizes the p-score. The cutoff can be changed by dragging the vertical line or by entering a cutoff value in the square labeled "Current cut-off".

Under the Survival Scatter plot the p-score landscape (black curve; left axis) is shown together with dead median separation (red curve; right axis). Dead median separation is the difference in median mRNA expression between patients who have died with high and low expression, respectively. It is calculated as follows: median FPKM expression of dead patients with high expression - median FPKM expression of dead patients with low expression. This is intended to aid the user in visually exploring custom cutoffs and the associated p-scores and dead median separation.

Individual patient data is displayed and can be filtered by clicking on one or more of the category buttons on the top of the page. Categories describing expression level and patient information include: high, low, alive, dead, female, male and tumor stages. The scale of the x-axis can be toggled between linear and log-scale by clicking on the "x log" button. Mouse-over function shows TCGA ID, patient information and mRNA expression (FPKM) for each patient.

& Survival analysisⁱ

Stage:

Survival analysis

Current cut offⁱ:
Best expression cut offⁱ: 7679.39
Median expressionⁱ: N/A
Median follow up timeⁱ: N/A
P scoreⁱ N/A
5-year survival highⁱ N/A
5-year survival lowⁱ N/A

TCGA RNA samplesⁱ

Average FPKM

8386.6

Number of samples

159

Samples

Sample	Description	FPKM
TCGA-DY-A1DF-01A	73 years, female, white, stage:iiic, dead, 734 days	36957.8
TCGA-DY-A1H8-01A	77 years, female, white, stage:iiia, dead, 992 days	28808.7
TCGA-EI-6514-01A	59 years, female, white, stage:iia, alive, 496 days	25146.7
TCGA-DY-A1DD-01A	77 years, female, white, stage:iiib, dead, 1741 days	24602.2
TCGA-BM-6198-01A	73 years, male, white, stage:iiib, alive, 646 days	21152.4
TCGA-AG-A032-01A	68 years, male, stage:iiib, alive, 1157 days	19170.0
TCGA-AG-A01J-01A	59 years, female, stage:iia, alive, 31 days	18332.0
TCGA-AG-A02N-01A	67 years, male, stage:ii, alive, 1885 days	18325.1
TCGA-AG-A026-01A	66 years, male, stage:ii, dead, 59 days	18123.0
TCGA-AF-A56K-01A	56 years, male, black or african american, stage:iia, alive, 2635 days	18070.3
TCGA-AG-3593-01A	72 years, female, stage:iia, alive, 1035 days	18033.1
TCGA-F5-6812-01A	67 years, male, white, stage:iia, alive, 1110 days	17645.5
TCGA-CL-5918-01A	90 years, female, white, stage:iia, alive, 218 days	16401.6
TCGA-AG-A011-01A	80 years, male, stage:iia, alive, 1126 days	16348.3
TCGA-AF-5654-01A	73 years, female, white, stage:i, dead, 512 days	15911.2
TCGA-F5-6571-01A	62 years, female, white, stage:iia, alive, 1288 days	15654.5
TCGA-G5-6572-01A	56 years, male, white, dead, 1432 days	14925.9
TCGA-AG-3882-01A	66 years, female, stage:i, alive, 608 days	14575.9
TCGA-AG-A002-01A	35 years, male, stage:i, alive, 638 days	14558.7
TCGA-CI-6624-01C	53 years, female, white, stage:i, alive, 1466 days	14487.4
TCGA-G5-6235-01A	72 years, male, white, stage:iiib, alive, 1696 days	14366.8
TCGA-AG-A014-01A	86 years, male, stage:i, alive, 485 days	14036.1
TCGA-DY-A1DG-01A	75 years, male, white, stage:iva, dead, 1566 days	13923.7
TCGA-AG-A00H-01A	75 years, male, stage:iia, alive, 790 days	13539.8
TCGA-G5-6641-01A	67 years, male, white, stage:iiia, alive, 804 days	13377.7
TCGA-AG-3898-01A	61 years, male, stage:iia, alive, 1461 days	13045.4
TCGA-AF-2691-01A	48 years, female, white, stage:i, alive, 1309 days	12958.3
TCGA-AG-A01N-01A	68 years, female, stage:iv, alive, 943 days	12860.4
TCGA-AG-3574-01A	89 years, female, stage:ii, dead, 1096 days	12836.6
TCGA-DY-A1DC-01A	72 years, female, white, stage:iia, dead, 1258 days	12566.2
TCGA-AG-3890-01A	62 years, male, stage:i, alive, 518 days	12108.5
TCGA-AG-A015-01A	64 years, female, stage:i, alive, 1096 days	12104.9
TCGA-AF-2692-01A	54 years, female, white, stage:iia, alive, 412 days	11944.6
TCGA-AG-4022-01A	59 years, female, stage:ii, alive, 1400 days	11802.3
TCGA-EI-6509-01A	53 years, male, white, stage:iiic, alive, 517 days	11595.9
TCGA-AH-6544-01A	60 years, male, white, alive, 1173 days	11584.2
TCGA-AG-A00C-01A	49 years, female, stage:iiib, alive, 183 days	11538.9
TCGA-AG-3600-01A	62 years, male, stage:iiic, alive, 184 days	11352.7
TCGA-AG-A023-01A	62 years, female, stage:iv, dead, 1581 days	11302.3
TCGA-AG-A025-01A	62 years, female, stage:i, alive, 1520 days	11224.2
TCGA-CL-4957-01A	79 years, female, dead, 425 days	11157.9
TCGA-EI-6510-01A	77 years, female, white, alive, 556 days	11147.8
TCGA-AG-A036-01A	71 years, male, stage:iii, alive, 3562 days	10748.9
TCGA-AF-6672-01A	43 years, male, white, stage:iv, alive, 748 days	10661.7
TCGA-AG-3893-01A	74 years, male, stage:iiib, alive, 1065 days	10333.2
TCGA-AG-A00Y-01A	68 years, male, stage:iia, alive, 700 days	10168.7
TCGA-AG-3732-01A	78 years, female, stage:i, alive, 1003 days	10060.8
TCGA-AG-3578-01A	76 years, female, stage:iia, alive, 974 days	9598.1
TCGA-AG-3909-01A	69 years, female, stage:iiib, alive, 608 days	9597.9
TCGA-AG-4001-01A	74 years, female, stage:iia, alive, 1096 days	9329.5
TCGA-F5-6813-01A	70 years, male, white, stage:iiic, dead, 598 days	9302.7
TCGA-AG-3584-01A	60 years, male, stage:iv, dead, 730 days	9227.9
TCGA-AG-3581-01A	63 years, male, stage:i, alive, 215 days	8775.5
TCGA-CI-6619-01B	41 years, male, white, stage:iv, alive, 184 days	8773.5
TCGA-AG-3583-01A	66 years, male, stage:iv, dead, 610 days	8717.2
TCGA-AG-3580-01A	67 years, male, stage:i, alive, 244 days	8646.4
TCGA-AH-6547-01A	79 years, female, white, dead, 76 days	8576.9
TCGA-AG-3586-01A	72 years, female, stage:iii, alive, 31 days	8524.5
TCGA-EI-6506-01A	78 years, female, white, stage:iia, alive, 625 days	8490.4
TCGA-AH-6903-01A	46 years, male, white, stage:iiib, alive, 592 days	8353.2
TCGA-DT-5265-01A	51 years, male, asian, stage:ii, alive, 384 days	8303.4
TCGA-CI-6621-01A	63 years, male, white, stage:iiib, alive, 419 days	8196.1
TCGA-AG-3612-01A	55 years, female, stage:iiib, alive, 608 days	8167.5
TCGA-AG-A020-01A	57 years, female, stage:iii, alive, 31 days	8132.4
TCGA-AG-A016-01A	55 years, male, stage:iv, alive, 276 days	7992.0
TCGA-AG-A02G-01A	66 years, male, stage:iv, dead, 1185 days	7717.5
TCGA-AG-3999-01A	61 years, female, stage:iiic, alive, 853 days	7685.6
TCGA-AG-3594-01A	77 years, male, stage:iia, dead, 61 days	7679.7
TCGA-EI-6881-01A	60 years, male, white, stage:iiia, alive, 499 days	7679.1
TCGA-F5-6465-01A	64 years, female, white, stage:iia, alive, 1506 days	7665.4
TCGA-AG-A02X-01A	77 years, male, stage:i, alive, 1247 days	7642.5
TCGA-AG-4008-01A	63 years, male, stage:iia, alive, 518 days	7641.5
TCGA-DC-6682-01A	57 years, male, white, stage:iia, alive, 762 days	7509.6
TCGA-EI-6513-01A	59 years, male, white, stage:iiib, alive, 497 days	7453.4
TCGA-CI-6623-01B	44 years, male, white, stage:i, alive, 1443 days	7447.0
TCGA-AG-3592-01A	68 years, male, stage:iia, alive, 1035 days	7440.5
TCGA-AG-3742-01A	85 years, female, stage:i, alive, 30 days	7373.7
TCGA-AF-A56L-01A	48 years, female, black or african american, stage:iiic, alive, 2007 days	7304.4
TCGA-AG-3878-01A	64 years, male, stage:i, alive, 30 days	7288.9
TCGA-EI-6511-01A	52 years, male, white, stage:iiib, alive, 482 days	7285.4
TCGA-AG-3725-01A	90 years, female, stage:iii, alive, 638 days	6990.2
TCGA-AH-6643-01A	50 years, male, white, stage:iiic, dead, 1314 days	6818.6
TCGA-AG-A008-01A	50 years, female, stage:i, alive, 424 days	6618.3
TCGA-AG-4005-01A	64 years, male, stage:iv, alive, 427 days	6604.5
TCGA-DY-A1DE-01A	56 years, female, white, stage:iia, alive, 3932 days	6594.6
TCGA-CI-6622-01A	74 years, male, white, stage:iib, alive, 1362 days	6546.7
TCGA-DC-6157-01A	48 years, male, black or african american, stage:i, alive, 1581 days	6511.0
TCGA-AG-3883-01A	69 years, male, stage:i, alive, 31 days	6495.9
TCGA-AG-3726-01A	63 years, female, stage:i, alive, 243 days	6433.2
TCGA-AG-3587-01A	65 years, male, stage:i, alive, 1400 days	6377.1
TCGA-AG-3582-01A	75 years, male, stage:iv, dead, 1096 days	6302.0
TCGA-G5-6233-01A	74 years, male, white, dead, 556 days	6275.3
TCGA-EF-5831-01A	72 years, male, white, stage:iia, alive, 127 days	6232.4
TCGA-CI-6620-01A	41 years, female, white, stage:iva, alive, 1009 days	6112.9
TCGA-F5-6702-01A	71 years, male, white, stage:iva, alive, 869 days	6103.2
TCGA-DC-6683-01A	43 years, male, white, stage:iiib, alive, 762 days	6097.3
TCGA-EI-6512-01A	64 years, female, white, stage:iiib, alive, 538 days	6040.5
TCGA-AG-3608-01A	79 years, female, stage:iia, alive, 485 days	6004.7
TCGA-AF-A56N-01A	47 years, female, black or african american, stage:iia, alive, 360 days	5953.0
TCGA-AF-2687-01A	57 years, male, white, stage:iiic, alive, 1427 days	5933.3
TCGA-EF-5830-01A	54 years, male, white, stage:iib, alive, 106 days	5913.2
TCGA-AG-3611-01A	72 years, male, stage:iia, alive, 424 days	5860.6
TCGA-DY-A0XA-01A	57 years, female, white, stage:iia, alive, 3846 days	5859.0
TCGA-F5-6811-01A	72 years, female, white, stage:iia, alive, 979 days	5537.3
TCGA-AF-6136-01A	72 years, female, white, stage:iiib, alive, 741 days	5440.0
TCGA-AH-6644-01A	73 years, male, white, alive, 838 days	5393.6
TCGA-AG-4007-01A	87 years, male, stage:iv, alive, 31 days	5291.4
TCGA-CL-5917-01A	71 years, female, white, stage:iiic, alive, 2376 days	5268.4
TCGA-AF-2690-01A	77 years, female, white, stage:iiic, dead, 524 days	5257.7
TCGA-AF-2693-01A	75 years, male, white, stage:i, alive, 1155 days	5151.0
TCGA-AG-3901-01A	67 years, female, stage:iiib, alive, 761 days	5149.3
TCGA-EI-6508-01A	48 years, female, white, stage:iiib, alive, 636 days	5129.6
TCGA-AG-4021-01A	84 years, female, stage:iv, dead, 121 days	5048.9
TCGA-AG-3902-01A	61 years, male, stage:iia, alive, 974 days	4968.5
TCGA-AG-3894-01A	65 years, male, stage:iia, alive, 426 days	4916.2
TCGA-F5-6464-01A	77 years, female, white, stage:iiic, dead, 303 days	4914.5
TCGA-AF-3911-01A	48 years, male, white, stage:iiic, alive, 1148 days	4858.4
TCGA-AF-3400-01A	54 years, male, white, stage:iia, alive, 1049 days	4817.5
TCGA-AG-3896-01A	85 years, female, stage:i, alive, 31 days	4794.8
TCGA-F5-6861-01A	60 years, female, white, stage:iia, alive, 1160 days	4726.9
TCGA-AG-3731-01A	65 years, male, stage:iv, alive, 1126 days	4675.7
TCGA-AF-4110-01A	77 years, male, white, stage:iva, alive, 912 days	4635.0
TCGA-DC-4749-01A	57 years, male, white, stage:i, alive, 762 days	4626.9
TCGA-AG-3591-01A	66 years, female, stage:iia, alive, 1035 days	4556.4
TCGA-AH-6549-01A	66 years, male, white, alive, 532 days	4180.9
TCGA-AG-3605-01A	85 years, female, stage:iv, alive, 30 days	4114.8
TCGA-AG-3599-01A	70 years, male, stage:i, alive, 366 days	4096.2
TCGA-DC-6681-01A	70 years, female, white, stage:iva, alive, 790 days	4048.4
TCGA-AF-6655-01A	66 years, male, white, stage:iiia, alive, 609 days	3983.1
TCGA-AG-3887-01A	68 years, male, stage:iia, alive, 1124 days	3979.4
TCGA-AG-3727-01A	78 years, female, stage:iii, alive, 30 days	3946.1
TCGA-F5-6864-01A	74 years, female, white, stage:iiib, alive, 379 days	3939.5
TCGA-AG-3885-01A	71 years, female, stage:iiib, alive, 546 days	3824.2
TCGA-F5-6814-01A	57 years, male, white, stage:iia, alive, 1131 days	3766.8
TCGA-AG-3892-01A	57 years, female, stage:i, alive, 396 days	3765.1
TCGA-DC-6156-01A	62 years, male, white, stage:iva, alive, 943 days	3518.1
TCGA-EI-6883-01A	63 years, male, white, stage:iic, alive, 350 days	3395.2
TCGA-DC-6158-01A	70 years, male, white, stage:i, dead, 334 days	3338.9
TCGA-AF-3913-01A	60 years, male, black or african american, stage:iv, dead, 316 days	3271.2
TCGA-AG-3598-01A	69 years, male, stage:iia, alive, 1522 days	3224.1
TCGA-F5-6863-01A	71 years, female, white, stage:iiib, dead, 361 days	3121.6
TCGA-DC-6160-01A	68 years, male, white, stage:i, alive, 1339 days	3042.4
TCGA-DC-6154-01A	57 years, female, white, stage:iva, alive, 365 days	3004.4
TCGA-AG-3881-01A	83 years, female, stage:iia, alive, 579 days	2934.8
TCGA-EI-6507-01A	60 years, male, white, stage:iia, alive, 607 days	2833.7
TCGA-AG-3609-01A	65 years, female, stage:iiic, alive, 608 days	2688.8
TCGA-EI-7002-01A	58 years, male, white, stage:iv, alive, 364 days	2679.3
TCGA-AG-3728-01A	73 years, male, stage:iiib, alive, 912 days	2637.8
TCGA-EI-6882-01A	59 years, male, white, stage:iia, alive, 262 days	2532.3
TCGA-AH-6897-01A	48 years, male, white, stage:i, alive, 804 days	2492.6
TCGA-EI-6917-01A	33 years, male, white, stage:iiia, alive, 531 days	2264.4
TCGA-EI-6885-01A	57 years, female, white, stage:iv, alive, 415 days	2203.7
TCGA-EI-6884-01A	71 years, male, white, stage:iiia, alive, 328 days	2120.3
TCGA-DC-4745-01A	49 years, female, white, stage:iiib, alive, 639 days	1647.0
TCGA-EI-7004-01A	37 years, female, white, alive, 257 days	1239.8
TCGA-DC-6155-01A	31 years, female, white, stage:iiia, alive, 425 days	1237.6
TCGA-AG-3575-01A	51 years, male, stage:ii, alive, 365 days	1235.6
TCGA-DC-5337-01A	69 years, male, white, stage:i, alive, 792 days	1196.5
TCGA-DC-5869-01A	62 years, female, black or african american, stage:iiib, alive, 943 days	1041.1
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