Expression of MT-CO3 in colorectal cancer

RECTUM ADENOCARCINOMA (READ) - Interactive survival scatter plotⁱ

The Survival Scatter plot shows the clinical status (i.e. dead or alive) for all individuals in the patient cohort, based on the same data that underlies the corresponding Kaplan-Meier plots. Patients that are alive at last time for follow-up are shown in blue and patients who have died during the study are shown in red.

The x-axis shows the expression levels (FPKM) of the investigated gene in the tumor tissue at the time of diagnosis. The y-axis shows the follow-up time after diagnosis (years). Both axes are complimented with kernel density curves demonstrating the data density over the axes. The top density plot shows the expression levels (FPKM) distribution among dead (red) and alive patients (blue). The right density plot shows the data density of the survived years of dead patients with high and low expression levels respectively, stratified using the cutoff indicated by the vertical dashed line through the Survival Scatter plot. This cutoff is automatically defined based on the FPKM cutoff that minimizes the p-score. The cutoff can be changed by dragging the vertical line or by entering a cutoff value in the square labeled "Current cut-off".

Under the Survival Scatter plot the p-score landscape (black curve; left axis) is shown together with dead median separation (red curve; right axis). Dead median separation is the difference in median mRNA expression between patients who have died with high and low expression, respectively. It is calculated as follows: median FPKM expression of dead patients with high expression - median FPKM expression of dead patients with low expression. This is intended to aid the user in visually exploring custom cutoffs and the associated p-scores and dead median separation.

Individual patient data is displayed and can be filtered by clicking on one or more of the category buttons on the top of the page. Categories describing expression level and patient information include: high, low, alive, dead, female, male and tumor stages. The scale of the x-axis can be toggled between linear and log-scale by clicking on the "x log" button. Mouse-over function shows TCGA ID, patient information and mRNA expression (FPKM) for each patient.

& Survival analysisⁱ

Stage:

Survival analysis

Current cut offⁱ:
Best expression cut offⁱ: 10936.9
Median expressionⁱ: N/A
Median follow up timeⁱ: N/A
P scoreⁱ N/A
5-year survival highⁱ N/A
5-year survival lowⁱ N/A

TCGA RNA samplesⁱ

Average FPKM

9358.2

Number of samples

159

Samples

Sample	Description	FPKM
TCGA-DY-A1DF-01A	73 years, female, white, stage:iiic, dead, 734 days	46110.3
TCGA-DY-A1DD-01A	77 years, female, white, stage:iiib, dead, 1741 days	31162.3
TCGA-DY-A1H8-01A	77 years, female, white, stage:iiia, dead, 992 days	26363.6
TCGA-BM-6198-01A	73 years, male, white, stage:iiib, alive, 646 days	26352.6
TCGA-AG-A011-01A	80 years, male, stage:iia, alive, 1126 days	20261.6
TCGA-F5-6812-01A	67 years, male, white, stage:iia, alive, 1110 days	19827.1
TCGA-AG-A01J-01A	59 years, female, stage:iia, alive, 31 days	19592.8
TCGA-CL-5918-01A	90 years, female, white, stage:iia, alive, 218 days	19563.2
TCGA-AF-A56K-01A	56 years, male, black or african american, stage:iia, alive, 2635 days	19170.2
TCGA-AG-A02N-01A	67 years, male, stage:ii, alive, 1885 days	17268.8
TCGA-DY-A1DG-01A	75 years, male, white, stage:iva, dead, 1566 days	17034.6
TCGA-AG-A032-01A	68 years, male, stage:iiib, alive, 1157 days	16976.6
TCGA-AG-3732-01A	78 years, female, stage:i, alive, 1003 days	16451.3
TCGA-G5-6641-01A	67 years, male, white, stage:iiia, alive, 804 days	16296.1
TCGA-AG-3591-01A	66 years, female, stage:iia, alive, 1035 days	16042.6
TCGA-AF-2691-01A	48 years, female, white, stage:i, alive, 1309 days	15412.4
TCGA-AG-A025-01A	62 years, female, stage:i, alive, 1520 days	14828.1
TCGA-DY-A1DC-01A	72 years, female, white, stage:iia, dead, 1258 days	14269.2
TCGA-AG-A026-01A	66 years, male, stage:ii, dead, 59 days	14175.9
TCGA-AG-3593-01A	72 years, female, stage:iia, alive, 1035 days	14068.6
TCGA-CL-4957-01A	79 years, female, dead, 425 days	14031.0
TCGA-AG-A00H-01A	75 years, male, stage:iia, alive, 790 days	14026.9
TCGA-EI-6510-01A	77 years, female, white, alive, 556 days	13969.6
TCGA-AG-3882-01A	66 years, female, stage:i, alive, 608 days	13913.9
TCGA-AG-3890-01A	62 years, male, stage:i, alive, 518 days	13912.1
TCGA-AG-3893-01A	74 years, male, stage:iiib, alive, 1065 days	13685.7
TCGA-AF-5654-01A	73 years, female, white, stage:i, dead, 512 days	13530.9
TCGA-AG-A015-01A	64 years, female, stage:i, alive, 1096 days	13508.1
TCGA-EI-6509-01A	53 years, male, white, stage:iiic, alive, 517 days	13435.7
TCGA-AH-6544-01A	60 years, male, white, alive, 1173 days	13431.8
TCGA-AG-A00C-01A	49 years, female, stage:iiib, alive, 183 days	13160.3
TCGA-AG-3898-01A	61 years, male, stage:iia, alive, 1461 days	12641.1
TCGA-EI-6514-01A	59 years, female, white, stage:iia, alive, 496 days	12586.4
TCGA-AG-3583-01A	66 years, male, stage:iv, dead, 610 days	12516.2
TCGA-F5-6813-01A	70 years, male, white, stage:iiic, dead, 598 days	12514.5
TCGA-CI-6619-01B	41 years, male, white, stage:iv, alive, 184 days	12140.8
TCGA-F5-6571-01A	62 years, female, white, stage:iia, alive, 1288 days	12108.1
TCGA-DT-5265-01A	51 years, male, asian, stage:ii, alive, 384 days	12075.0
TCGA-AG-3725-01A	90 years, female, stage:iii, alive, 638 days	11683.2
TCGA-AG-4008-01A	63 years, male, stage:iia, alive, 518 days	11553.4
TCGA-AH-6547-01A	79 years, female, white, dead, 76 days	11530.7
TCGA-AF-2693-01A	75 years, male, white, stage:i, alive, 1155 days	11272.3
TCGA-CI-6624-01C	53 years, female, white, stage:i, alive, 1466 days	11144.2
TCGA-G5-6233-01A	74 years, male, white, dead, 556 days	11131.5
TCGA-AG-3600-01A	62 years, male, stage:iiic, alive, 184 days	11111.7
TCGA-AG-3592-01A	68 years, male, stage:iia, alive, 1035 days	10966.4
TCGA-AG-3584-01A	60 years, male, stage:iv, dead, 730 days	10943.8
TCGA-AG-A023-01A	62 years, female, stage:iv, dead, 1581 days	10937.3
TCGA-EI-6881-01A	60 years, male, white, stage:iiia, alive, 499 days	10936.5
TCGA-AG-A036-01A	71 years, male, stage:iii, alive, 3562 days	10697.2
TCGA-AF-3911-01A	48 years, male, white, stage:iiic, alive, 1148 days	10694.2
TCGA-G5-6235-01A	72 years, male, white, stage:iiib, alive, 1696 days	10682.4
TCGA-AH-6903-01A	46 years, male, white, stage:iiib, alive, 592 days	10285.6
TCGA-AG-A01N-01A	68 years, female, stage:iv, alive, 943 days	10087.7
TCGA-G5-6572-01A	56 years, male, white, dead, 1432 days	10051.2
TCGA-AG-3883-01A	69 years, male, stage:i, alive, 31 days	9992.6
TCGA-AF-A56L-01A	48 years, female, black or african american, stage:iiic, alive, 2007 days	9847.1
TCGA-AG-A00Y-01A	68 years, male, stage:iia, alive, 700 days	9835.4
TCGA-EI-6513-01A	59 years, male, white, stage:iiib, alive, 497 days	9819.9
TCGA-AG-A002-01A	35 years, male, stage:i, alive, 638 days	9791.9
TCGA-AF-2692-01A	54 years, female, white, stage:iia, alive, 412 days	9529.5
TCGA-AF-2690-01A	77 years, female, white, stage:iiic, dead, 524 days	9451.3
TCGA-AF-6136-01A	72 years, female, white, stage:iiib, alive, 741 days	9359.8
TCGA-AG-3580-01A	67 years, male, stage:i, alive, 244 days	9329.6
TCGA-AG-A014-01A	86 years, male, stage:i, alive, 485 days	9240.3
TCGA-AG-3612-01A	55 years, female, stage:iiib, alive, 608 days	9096.9
TCGA-AG-3999-01A	61 years, female, stage:iiic, alive, 853 days	9080.7
TCGA-DY-A0XA-01A	57 years, female, white, stage:iia, alive, 3846 days	8993.5
TCGA-DC-6682-01A	57 years, male, white, stage:iia, alive, 762 days	8979.6
TCGA-CI-6622-01A	74 years, male, white, stage:iib, alive, 1362 days	8953.5
TCGA-AG-3742-01A	85 years, female, stage:i, alive, 30 days	8933.5
TCGA-AF-2687-01A	57 years, male, white, stage:iiic, alive, 1427 days	8893.0
TCGA-AG-3586-01A	72 years, female, stage:iii, alive, 31 days	8809.2
TCGA-CI-6623-01B	44 years, male, white, stage:i, alive, 1443 days	8738.6
TCGA-AG-3578-01A	76 years, female, stage:iia, alive, 974 days	8714.3
TCGA-DC-6157-01A	48 years, male, black or african american, stage:i, alive, 1581 days	8629.7
TCGA-CI-6620-01A	41 years, female, white, stage:iva, alive, 1009 days	8602.6
TCGA-AG-A008-01A	50 years, female, stage:i, alive, 424 days	8485.2
TCGA-AH-6643-01A	50 years, male, white, stage:iiic, dead, 1314 days	8412.4
TCGA-AG-3909-01A	69 years, female, stage:iiib, alive, 608 days	8395.1
TCGA-AG-3574-01A	89 years, female, stage:ii, dead, 1096 days	8236.9
TCGA-AF-6655-01A	66 years, male, white, stage:iiia, alive, 609 days	8130.8
TCGA-AG-3878-01A	64 years, male, stage:i, alive, 30 days	8080.6
TCGA-AG-4007-01A	87 years, male, stage:iv, alive, 31 days	7983.7
TCGA-AG-3582-01A	75 years, male, stage:iv, dead, 1096 days	7957.1
TCGA-CI-6621-01A	63 years, male, white, stage:iiib, alive, 419 days	7915.0
TCGA-AF-6672-01A	43 years, male, white, stage:iv, alive, 748 days	7894.3
TCGA-EI-6506-01A	78 years, female, white, stage:iia, alive, 625 days	7883.2
TCGA-AF-A56N-01A	47 years, female, black or african american, stage:iia, alive, 360 days	7710.9
TCGA-EI-6508-01A	48 years, female, white, stage:iiib, alive, 636 days	7681.8
TCGA-AG-3594-01A	77 years, male, stage:iia, dead, 61 days	7599.7
TCGA-AG-3611-01A	72 years, male, stage:iia, alive, 424 days	7508.5
TCGA-AG-3608-01A	79 years, female, stage:iia, alive, 485 days	7405.7
TCGA-AG-3581-01A	63 years, male, stage:i, alive, 215 days	7257.3
TCGA-EI-6883-01A	63 years, male, white, stage:iic, alive, 350 days	7197.6
TCGA-AG-A020-01A	57 years, female, stage:iii, alive, 31 days	7187.4
TCGA-EI-6511-01A	52 years, male, white, stage:iiib, alive, 482 days	7088.8
TCGA-DY-A1DE-01A	56 years, female, white, stage:iia, alive, 3932 days	7065.4
TCGA-AG-3605-01A	85 years, female, stage:iv, alive, 30 days	7048.0
TCGA-AH-6644-01A	73 years, male, white, alive, 838 days	6832.1
TCGA-AG-3902-01A	61 years, male, stage:iia, alive, 974 days	6724.2
TCGA-EF-5830-01A	54 years, male, white, stage:iib, alive, 106 days	6703.5
TCGA-EF-5831-01A	72 years, male, white, stage:iia, alive, 127 days	6679.0
TCGA-AG-3901-01A	67 years, female, stage:iiib, alive, 761 days	6678.6
TCGA-AG-3599-01A	70 years, male, stage:i, alive, 366 days	6624.0
TCGA-AG-4005-01A	64 years, male, stage:iv, alive, 427 days	6598.0
TCGA-AF-4110-01A	77 years, male, white, stage:iva, alive, 912 days	6584.7
TCGA-AF-3400-01A	54 years, male, white, stage:iia, alive, 1049 days	6575.0
TCGA-AG-4001-01A	74 years, female, stage:iia, alive, 1096 days	6540.6
TCGA-F5-6465-01A	64 years, female, white, stage:iia, alive, 1506 days	6481.9
TCGA-AG-3887-01A	68 years, male, stage:iia, alive, 1124 days	6427.0
TCGA-EI-6512-01A	64 years, female, white, stage:iiib, alive, 538 days	6401.4
TCGA-AG-A02G-01A	66 years, male, stage:iv, dead, 1185 days	6353.8
TCGA-AG-3896-01A	85 years, female, stage:i, alive, 31 days	6337.5
TCGA-DC-6681-01A	70 years, female, white, stage:iva, alive, 790 days	6088.5
TCGA-AG-3587-01A	65 years, male, stage:i, alive, 1400 days	5982.4
TCGA-F5-6861-01A	60 years, female, white, stage:iia, alive, 1160 days	5980.8
TCGA-DC-4749-01A	57 years, male, white, stage:i, alive, 762 days	5879.2
TCGA-AG-4021-01A	84 years, female, stage:iv, dead, 121 days	5822.5
TCGA-AG-3894-01A	65 years, male, stage:iia, alive, 426 days	5744.5
TCGA-F5-6811-01A	72 years, female, white, stage:iia, alive, 979 days	5714.0
TCGA-AG-3598-01A	69 years, male, stage:iia, alive, 1522 days	5602.6
TCGA-AG-A016-01A	55 years, male, stage:iv, alive, 276 days	5568.1
TCGA-AG-3892-01A	57 years, female, stage:i, alive, 396 days	5461.0
TCGA-F5-6702-01A	71 years, male, white, stage:iva, alive, 869 days	5340.9
TCGA-DC-6156-01A	62 years, male, white, stage:iva, alive, 943 days	5196.6
TCGA-F5-6464-01A	77 years, female, white, stage:iiic, dead, 303 days	5189.4
TCGA-AG-3731-01A	65 years, male, stage:iv, alive, 1126 days	5125.1
TCGA-AH-6549-01A	66 years, male, white, alive, 532 days	5114.7
TCGA-CL-5917-01A	71 years, female, white, stage:iiic, alive, 2376 days	5049.5
TCGA-AG-3885-01A	71 years, female, stage:iiib, alive, 546 days	5014.0
TCGA-AF-3913-01A	60 years, male, black or african american, stage:iv, dead, 316 days	4999.8
TCGA-DC-6160-01A	68 years, male, white, stage:i, alive, 1339 days	4999.0
TCGA-DC-6683-01A	43 years, male, white, stage:iiib, alive, 762 days	4720.0
TCGA-AG-A02X-01A	77 years, male, stage:i, alive, 1247 days	4719.5
TCGA-DC-4745-01A	49 years, female, white, stage:iiib, alive, 639 days	4681.9
TCGA-AG-4022-01A	59 years, female, stage:ii, alive, 1400 days	4591.5
TCGA-F5-6814-01A	57 years, male, white, stage:iia, alive, 1131 days	4443.3
TCGA-F5-6864-01A	74 years, female, white, stage:iiib, alive, 379 days	4358.7
TCGA-AG-3728-01A	73 years, male, stage:iiib, alive, 912 days	4273.5
TCGA-DC-6158-01A	70 years, male, white, stage:i, dead, 334 days	4139.5
TCGA-AG-3609-01A	65 years, female, stage:iiic, alive, 608 days	4087.9
TCGA-AG-3881-01A	83 years, female, stage:iia, alive, 579 days	3971.8
TCGA-DC-6154-01A	57 years, female, white, stage:iva, alive, 365 days	3793.1
TCGA-EI-6917-01A	33 years, male, white, stage:iiia, alive, 531 days	3698.4
TCGA-F5-6863-01A	71 years, female, white, stage:iiib, dead, 361 days	3277.0
TCGA-AG-3575-01A	51 years, male, stage:ii, alive, 365 days	3221.9
TCGA-EI-6884-01A	71 years, male, white, stage:iiia, alive, 328 days	3165.9
TCGA-DC-5337-01A	69 years, male, white, stage:i, alive, 792 days	3123.5
TCGA-EI-6882-01A	59 years, male, white, stage:iia, alive, 262 days	2968.0
TCGA-EI-6885-01A	57 years, female, white, stage:iv, alive, 415 days	2828.1
TCGA-AG-3726-01A	63 years, female, stage:i, alive, 243 days	2776.8
TCGA-AH-6897-01A	48 years, male, white, stage:i, alive, 804 days	2719.6
TCGA-EI-7002-01A	58 years, male, white, stage:iv, alive, 364 days	2709.7
TCGA-DC-5869-01A	62 years, female, black or african american, stage:iiib, alive, 943 days	2544.5
TCGA-EI-6507-01A	60 years, male, white, stage:iia, alive, 607 days	2408.4
TCGA-DC-6155-01A	31 years, female, white, stage:iiia, alive, 425 days	1964.7
TCGA-AG-3727-01A	78 years, female, stage:iii, alive, 30 days	1890.1
TCGA-EI-7004-01A	37 years, female, white, alive, 257 days	1594.5
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