Expression of HLA-A in pancreatic cancer

PANCREATIC CANCER - Interactive survival scatter plotⁱ

The Survival Scatter plot shows the clinical status (i.e. dead or alive) for all individuals in the patient cohort, based on the same data that underlies the corresponding Kaplan-Meier plots. Patients that are alive at last time for follow-up are shown in blue and patients who have died during the study are shown in red.

The x-axis shows the expression levels (FPKM) of the investigated gene in the tumor tissue at the time of diagnosis. The y-axis shows the follow-up time after diagnosis (years). Both axes are complimented with kernel density curves demonstrating the data density over the axes. The top density plot shows the expression levels (FPKM) distribution among dead (red) and alive patients (blue). The right density plot shows the data density of the survived years of dead patients with high and low expression levels respectively, stratified using the cutoff indicated by the vertical dashed line through the Survival Scatter plot. This cutoff is automatically defined based on the FPKM cutoff that minimizes the p-score. The cutoff can be changed by dragging the vertical line or by entering a cutoff value in the square labeled "Current cut-off".

Under the Survival Scatter plot the p-score landscape (black curve; left axis) is shown together with dead median separation (red curve; right axis). Dead median separation is the difference in median mRNA expression between patients who have died with high and low expression, respectively. It is calculated as follows: median FPKM expression of dead patients with high expression - median FPKM expression of dead patients with low expression. This is intended to aid the user in visually exploring custom cutoffs and the associated p-scores and dead median separation.

Individual patient data is displayed and can be filtered by clicking on one or more of the category buttons on the top of the page. Categories describing expression level and patient information include: high, low, alive, dead, female, male and tumor stages. The scale of the x-axis can be toggled between linear and log-scale by clicking on the "x log" button. Mouse-over function shows TCGA ID, patient information and mRNA expression (FPKM) for each patient.

& Survival analysisⁱ

HLA-A is not prognostic in pancreatic cancer

Stage:

Survival analysis

Current cut offⁱ:
Best expression cut offⁱ: 618.7
Median expressionⁱ: N/A
Median follow up timeⁱ: N/A
P scoreⁱ N/A
5-year survival highⁱ N/A
5-year survival lowⁱ N/A

TCGA RNA samplesⁱ

Average FPKM

538.3

Number of samples

176

Samples

Sample	Description	FPKM
TCGA-FB-AAPQ-01A	65 years, male, white, stage:iib, dead, 1130 days	1252.2
TCGA-IB-AAUN-01A	74 years, female, white, stage:ib, dead, 144 days	1250.1
TCGA-US-A77E-01A	73 years, male, white, stage:iib, dead, 430 days	1237.6
TCGA-HZ-A49I-01A	77 years, male, white, stage:iib, dead, 308 days	1116.7
TCGA-M8-A5N4-01A	48 years, female, stage:iia, alive, 584 days	1096.2
TCGA-HZ-8637-01A	76 years, female, white, stage:iib, dead, 517 days	1092.6
TCGA-HV-A7OL-01A	70 years, male, asian, stage:iia, alive, 252 days	1067.1
TCGA-HV-AA8X-01A	75 years, female, asian, stage:iib, dead, 532 days	984.7
TCGA-F2-A8YN-01A	76 years, male, white, stage:iia, alive, 517 days	975.1
TCGA-IB-AAUO-01A	64 years, female, white, stage:iib, dead, 239 days	955.2
TCGA-OE-A75W-01A	75 years, male, white, stage:iia, dead, 267 days	940.6
TCGA-FB-AAQ3-01A	65 years, female, white, stage:iib, dead, 31 days	915.7
TCGA-F2-A7TX-01A	77 years, male, white, stage:iib, dead, 95 days	866.6
TCGA-3A-A9IO-01A	56 years, male, white, alive, 1942 days	854.6
TCGA-Z5-AAPL-01A	74 years, female, white, stage:iia, alive, 467 days	850.1
TCGA-IB-A7M4-01A	81 years, male, white, stage:iib, alive, 483 days	848.0
TCGA-FB-A4P5-01A	69 years, female, white, stage:iib, dead, 179 days	843.3
TCGA-2J-AAB4-01A	48 years, male, white, stage:iib, alive, 729 days	836.4
TCGA-LB-A8F3-01A	64 years, female, black or african american, stage:iia, alive, 379 days	809.2
TCGA-XN-A8T5-01A	53 years, female, white, stage:ib, alive, 720 days	800.8
TCGA-IB-7651-01A	64 years, female, white, stage:iib, dead, 603 days	794.8
TCGA-US-A776-01A	61 years, male, white, stage:iia, alive, 1216 days	792.6
TCGA-3A-A9J0-01A	75 years, male, white, stage:iib, alive, 743 days	767.3
TCGA-IB-A5ST-01A	64 years, female, white, stage:iib, alive, 635 days	759.3
TCGA-HZ-A4BH-01A	75 years, male, white, stage:iib, alive, 194 days	754.8
TCGA-IB-7885-01A	78 years, female, white, stage:iib, alive, 1257 days	741.3
TCGA-RL-AAAS-01A	60 years, female, white, stage:ib, alive, 9 days	736.3
TCGA-IB-AAUS-01A	84 years, female, white, stage:iib, alive, 225 days	731.6
TCGA-2J-AAB1-01A	65 years, male, white, stage:iib, dead, 66 days	730.5
TCGA-2L-AAQL-01A	82 years, male, white, stage:iib, dead, 292 days	728.6
TCGA-3E-AAAY-01A	67 years, male, white, stage:iib, alive, 2285 days	715.3
TCGA-IB-AAUR-01A	67 years, male, white, stage:iib, alive, 338 days	702.5
TCGA-YY-A8LH-01A	61 years, female, white, stage:iib, alive, 2016 days	699.1
TCGA-FB-AAQ6-01A	85 years, male, white, stage:ia, dead, 244 days	693.1
TCGA-HV-A5A5-01A	61 years, female, asian, stage:iib, alive, 289 days	691.6
TCGA-FB-AAPY-01A	71 years, male, white, stage:iib, dead, 1059 days	676.3
TCGA-HZ-A77Q-01A	55 years, female, white, stage:iib, alive, 33 days	675.0
TCGA-IB-7887-01A	62 years, female, white, stage:iib, dead, 110 days	665.5
TCGA-XD-AAUI-01A	50 years, female, white, stage:iib, dead, 366 days	664.1
TCGA-XD-AAUL-01A	56 years, male, white, stage:iia, alive, 498 days	661.8
TCGA-PZ-A5RE-01A	44 years, female, white, stage:iib, dead, 470 days	658.2
TCGA-HZ-A77O-01A	77 years, female, white, stage:iib, dead, 160 days	651.5
TCGA-IB-7646-01A	60 years, male, white, stage:iib, dead, 145 days	651.4
TCGA-2L-AAQI-01A	66 years, male, white, stage:iib, dead, 103 days	643.0
TCGA-FB-AAQ1-01A	49 years, male, white, stage:iib, dead, 123 days	642.2
TCGA-IB-AAUQ-01A	50 years, male, white, stage:iib, dead, 183 days	641.7
TCGA-HZ-8001-01A	69 years, male, white, stage:iii, alive, 706 days	641.6
TCGA-IB-A5SO-01A	71 years, male, white, stage:iib, dead, 365 days	632.8
TCGA-US-A77J-01A	81 years, female, white, stage:iib, dead, 568 days	632.8
TCGA-3A-A9IC-01A	61 years, female, white, stage:iib, dead, 738 days	629.2
TCGA-HZ-7289-01A	77 years, male, white, stage:iib, dead, 661 days	626.6
TCGA-Q3-A5QY-01A	58 years, male, white, stage:iib, alive, 416 days	626.3
TCGA-F2-A44G-01A	79 years, female, white, stage:iib, dead, 233 days	622.9
TCGA-HZ-A9TJ-01A	70 years, male, white, stage:iv, alive, 603 days	614.5
TCGA-IB-AAUT-01A	65 years, male, white, stage:iib, alive, 287 days	612.0
TCGA-FB-A5VM-01A	74 years, male, white, stage:ib, dead, 498 days	610.4
TCGA-IB-AAUU-01A	35 years, male, white, stage:iib, alive, 245 days	605.5
TCGA-YH-A8SY-01A	73 years, female, white, alive, 388 days	605.4
TCGA-3A-A9IS-01A	67 years, male, white, stage:ib, alive, 998 days	604.6
TCGA-IB-AAUP-01A	68 years, male, white, stage:iib, alive, 431 days	602.4
TCGA-2J-AABK-01A	71 years, male, white, stage:iib, alive, 484 days	597.2
TCGA-H6-A45N-01A	88 years, female, white, stage:iib, dead, 421 days	595.5
TCGA-Q3-AA2A-01A	64 years, female, white, stage:ib, alive, 95 days	594.9
TCGA-2J-AAB8-01A	71 years, male, white, stage:iib, alive, 80 days	589.4
TCGA-FB-A78T-01A	71 years, female, white, stage:iib, dead, 375 days	583.5
TCGA-FB-AAPS-01A	62 years, female, white, stage:iib, alive, 228 days	582.1
TCGA-IB-7654-01A	80 years, male, white, stage:iib, dead, 476 days	579.0
TCGA-HZ-A4BK-01A	72 years, male, white, stage:iib, alive, 657 days	577.5
TCGA-3A-A9IH-01A	66 years, female, white, stage:ia, alive, 1021 days	577.2
TCGA-2J-AABH-01A	61 years, male, white, stage:iia, alive, 1287 days	576.4
TCGA-US-A774-01A	76 years, female, white, stage:iib, dead, 695 days	574.0
TCGA-HZ-8638-01A	84 years, female, white, stage:ia, dead, 151 days	569.1
TCGA-IB-A5SP-01A	77 years, male, white, stage:iia, alive, 482 days	568.2
TCGA-IB-A5SS-01A	64 years, female, white, stage:iib, dead, 460 days	567.0
TCGA-HV-A7OP-01A	72 years, male, asian, stage:iib, alive, 978 days	565.3
TCGA-HZ-7918-01A	72 years, male, white, stage:iib, alive, 969 days	563.9
TCGA-HV-A5A4-01A	72 years, female, asian, stage:iia, alive, 232 days	553.5
TCGA-FB-AAPP-01A	71 years, male, white, stage:iib, dead, 485 days	552.0
TCGA-IB-7649-01A	73 years, female, stage:iib, dead, 467 days	551.6
TCGA-2J-AAB6-01A	75 years, male, white, stage:iia, dead, 293 days	551.5
TCGA-HZ-A49G-01A	58 years, female, white, stage:iib, alive, 660 days	551.4
TCGA-YB-A89D-01A	59 years, male, white, stage:iib, alive, 350 days	550.9
TCGA-IB-A5SQ-01A	56 years, female, white, stage:ib, dead, 219 days	543.8
TCGA-FB-AAPZ-01A	54 years, male, white, stage:iib, alive, 716 days	535.4
TCGA-S4-A8RP-01A	77 years, female, white, stage:iib, dead, 702 days	528.8
TCGA-H8-A6C1-01A	53 years, male, white, stage:iia, alive, 671 days	519.5
TCGA-HV-A5A6-01A	65 years, female, asian, stage:iib, dead, 2036 days	518.8
TCGA-HZ-7923-01A	65 years, male, white, stage:iia, alive, 314 days	514.2
TCGA-HZ-A49H-01A	68 years, female, white, stage:iib, alive, 491 days	513.2
TCGA-2J-AABP-01A	58 years, female, white, stage:iib, alive, 463 days	508.6
TCGA-2J-AABR-01A	60 years, female, white, stage:iia, alive, 438 days	490.4
TCGA-HZ-8005-01A	81 years, male, white, stage:iib, dead, 120 days	488.0
TCGA-FB-A545-01A	72 years, female, white, stage:iib, dead, 732 days	486.0
TCGA-F2-6879-01A	57 years, male, white, stage:iib, dead, 334 days	484.3
TCGA-3A-A9IU-01A	65 years, male, white, stage:iib, dead, 458 days	483.4
TCGA-3A-A9IB-01A	69 years, female, white, stage:iib, dead, 224 days	482.2
TCGA-IB-7645-01A	44 years, female, stage:iib, dead, 1502 days	468.5
TCGA-HZ-7925-01A	66 years, male, white, stage:iib, dead, 614 days	468.2
TCGA-3A-A9IL-01A	39 years, female, white, stage:i, alive, 2741 days	459.1
TCGA-3A-A9I7-01A	45 years, male, black or african american, stage:iib, alive, 1323 days	458.7
TCGA-FB-A4P6-01A	54 years, male, white, stage:iib, alive, 767 days	457.0
TCGA-2J-AABU-01A	56 years, male, white, stage:iib, dead, 277 days	457.0
TCGA-2J-AABF-01A	73 years, male, white, stage:iib, dead, 691 days	455.3
TCGA-RB-A7B8-01A	81 years, female, white, stage:iib, dead, 466 days	453.4
TCGA-XD-AAUH-01A	57 years, female, white, stage:iib, alive, 395 days	450.8
TCGA-HV-AA8V-01A	50 years, male, asian, stage:iib, alive, 920 days	447.1
TCGA-IB-7891-01A	49 years, female, white, stage:iib, dead, 913 days	445.9
TCGA-HZ-7926-01A	57 years, male, black or african american, stage:iib, dead, 518 days	445.3
TCGA-FB-A7DR-01A	48 years, male, asian, stage:iia, dead, 353 days	443.9
TCGA-IB-7889-01A	86 years, female, white, stage:iib, dead, 481 days	443.4
TCGA-IB-7652-01A	49 years, female, asian, stage:iib, alive, 1116 days	436.1
TCGA-LB-A7SX-01A	74 years, female, black or african american, stage:iib, dead, 393 days	434.3
TCGA-2J-AABI-01A	55 years, female, white, stage:iia, alive, 969 days	432.4
TCGA-F2-7276-01A	64 years, male, white, stage:iib, dead, 216 days	429.5
TCGA-3A-A9I5-01A	58 years, male, white, alive, 1794 days	429.3
TCGA-F2-7273-01A	54 years, male, black or african american, stage:iib, dead, 592 days	429.0
TCGA-IB-7644-01A	65 years, female, white, stage:iv, dead, 394 days	428.8
TCGA-HZ-7924-01A	60 years, female, white, stage:iia, alive, 840 days	427.7
TCGA-2J-AABA-01A	55 years, male, white, stage:iib, dead, 607 days	423.1
TCGA-2J-AABE-01A	73 years, male, white, stage:iia, alive, 676 days	421.7
TCGA-2J-AABT-01A	72 years, female, white, stage:iib, alive, 319 days	421.6
TCGA-2L-AAQJ-01A	49 years, female, white, stage:iii, dead, 394 days	419.8
TCGA-3A-A9IN-01A	62 years, female, white, stage:ib, alive, 2084 days	413.8
TCGA-HZ-A8P1-01A	81 years, male, white, stage:ib, alive, 7 days	413.1
TCGA-FB-AAPU-01A	41 years, female, asian, stage:iia, dead, 381 days	412.6
TCGA-HZ-7920-01A	71 years, male, white, stage:ib, dead, 236 days	411.3
TCGA-US-A77G-01A	64 years, male, white, stage:iib, dead, 12 days	411.1
TCGA-FB-AAQ0-01A	68 years, male, white, stage:iia, dead, 473 days	409.4
TCGA-3A-A9IZ-01A	47 years, male, white, stage:iib, dead, 308 days	399.3
TCGA-IB-A7LX-01A	57 years, male, white, stage:iib, dead, 250 days	397.7
TCGA-RB-AA9M-01A	43 years, male, white, stage:iib, alive, 286 days	397.4
TCGA-IB-AAUW-01A	63 years, female, white, stage:iib, dead, 230 days	389.4
TCGA-2J-AAB9-01A	71 years, female, white, stage:iib, dead, 627 days	386.1
TCGA-2J-AABO-01A	43 years, male, white, stage:iib, alive, 440 days	377.3
TCGA-S4-A8RO-01A	75 years, female, white, stage:iib, alive, 525 days	376.2
TCGA-FB-AAQ2-01A	81 years, female, white, stage:iib, dead, 153 days	375.9
TCGA-HZ-8519-01A	73 years, male, white, stage:ia, alive, 454 days	375.1
TCGA-IB-7888-01A	66 years, female, black or african american, stage:iia, dead, 1332 days	366.9
TCGA-3A-A9IV-01A	59 years, female, white, stage:ib, alive, 1103 days	365.4
TCGA-IB-7897-01A	54 years, female, white, stage:iib, dead, 486 days	364.7
TCGA-XN-A8T3-01A	67 years, male, white, stage:ib, alive, 951 days	358.5
TCGA-3A-A9I9-01A	67 years, male, white, stage:iia, dead, 634 days	350.6
TCGA-HV-A5A3-01A	50 years, male, asian, stage:iia, dead, 128 days	350.2
TCGA-HZ-8636-01A	58 years, female, white, stage:iv, dead, 545 days	349.9
TCGA-S4-A8RM-01A	67 years, male, white, stage:iib, alive, 737 days	344.2
TCGA-IB-7893-01A	64 years, male, white, stage:iia, dead, 117 days	340.2
TCGA-2L-AAQE-01A	56 years, male, white, stage:iib, dead, 684 days	337.9
TCGA-XD-AAUG-01A	66 years, female, white, stage:iv, alive, 420 days	335.7
TCGA-3A-A9IJ-01A	65 years, male, white, stage:ib, alive, 1854 days	335.2
TCGA-IB-A6UF-01A	63 years, male, white, stage:iib, alive, 666 days	333.3
TCGA-F2-A44H-01A	65 years, male, white, stage:iia, alive, 586 days	331.6
TCGA-3A-A9IX-01A	40 years, male, white, stage:ia, alive, 1037 days	329.7
TCGA-HZ-8002-01A	61 years, male, white, stage:iib, dead, 366 days	322.7
TCGA-IB-8127-01A	59 years, male, white, stage:iib, alive, 522 days	322.1
TCGA-IB-7890-01A	73 years, male, stage:ib, dead, 598 days	321.6
TCGA-US-A779-01A	54 years, female, white, stage:iib, dead, 511 days	320.6
TCGA-HZ-8003-01A	65 years, female, white, stage:iib, dead, 596 days	319.7
TCGA-3A-A9IR-01A	64 years, female, white, stage:ib, alive, 1542 days	313.0
TCGA-IB-7886-01A	80 years, male, white, stage:iib, dead, 123 days	311.3
TCGA-HZ-7922-01A	61 years, female, white, stage:iib, alive, 4 days	284.5
TCGA-LB-A9Q5-01A	63 years, female, white, stage:iib, dead, 313 days	269.0
TCGA-HZ-8315-01A	54 years, female, white, stage:iia, dead, 299 days	269.0
TCGA-HZ-A77P-01A	77 years, male, white, stage:iib, alive, 330 days	254.7
TCGA-IB-A6UG-01A	65 years, male, white, stage:iib, dead, 41 days	241.4
TCGA-L1-A7W4-01A	48 years, female, white, stage:iib, dead, 278 days	240.9
TCGA-3E-AAAZ-01A	71 years, male, white, stage:iia, dead, 2182 days	231.7
TCGA-IB-AAUV-01A	49 years, male, white, stage:iib, alive, 404 days	230.9
TCGA-HZ-7919-01A	52 years, female, white, stage:iib, dead, 593 days	229.3
TCGA-HZ-8317-01A	69 years, female, white, stage:iib, dead, 378 days	222.7
TCGA-H6-8124-01A	56 years, female, white, stage:iib, alive, 392 days	211.6
TCGA-IB-8126-01A	80 years, female, white, stage:iii, alive, 462 days	209.3
TCGA-2L-AAQA-01A	76 years, male, white, stage:iib, dead, 143 days	201.4
TCGA-IB-AAUM-01A	76 years, male, white, stage:iib, alive, 8 days	187.0
TCGA-2J-AABV-01A	74 years, male, white, stage:iib, dead, 652 days	174.9
TCGA-2L-AAQM-01A	52 years, male, white, stage:iib, alive, 1383 days	173.1
TCGA-F2-6880-01A	70 years, male, white, stage:iib, alive, 289 days	64.3
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PANCREATIC CANCER - Protein expressionⁱ

Pending cancer tissue analysis