Expression of MT-ATP8 in colorectal cancer

RECTUM ADENOCARCINOMA (READ) - Interactive survival scatter plotⁱ

The Survival Scatter plot shows the clinical status (i.e. dead or alive) for all individuals in the patient cohort, based on the same data that underlies the corresponding Kaplan-Meier plots. Patients that are alive at last time for follow-up are shown in blue and patients who have died during the study are shown in red.

The x-axis shows the expression levels (FPKM) of the investigated gene in the tumor tissue at the time of diagnosis. The y-axis shows the follow-up time after diagnosis (years). Both axes are complimented with kernel density curves demonstrating the data density over the axes. The top density plot shows the expression levels (FPKM) distribution among dead (red) and alive patients (blue). The right density plot shows the data density of the survived years of dead patients with high and low expression levels respectively, stratified using the cutoff indicated by the vertical dashed line through the Survival Scatter plot. This cutoff is automatically defined based on the FPKM cutoff that minimizes the p-score. The cutoff can be changed by dragging the vertical line or by entering a cutoff value in the square labeled "Current cut-off".

Under the Survival Scatter plot the p-score landscape (black curve; left axis) is shown together with dead median separation (red curve; right axis). Dead median separation is the difference in median mRNA expression between patients who have died with high and low expression, respectively. It is calculated as follows: median FPKM expression of dead patients with high expression - median FPKM expression of dead patients with low expression. This is intended to aid the user in visually exploring custom cutoffs and the associated p-scores and dead median separation.

Individual patient data is displayed and can be filtered by clicking on one or more of the category buttons on the top of the page. Categories describing expression level and patient information include: high, low, alive, dead, female, male and tumor stages. The scale of the x-axis can be toggled between linear and log-scale by clicking on the "x log" button. Mouse-over function shows TCGA ID, patient information and mRNA expression (FPKM) for each patient.

& Survival analysisⁱ

Stage:

Survival analysis

Current cut offⁱ:
Best expression cut offⁱ: 2309.39
Median expressionⁱ: N/A
Median follow up timeⁱ: N/A
P scoreⁱ N/A
5-year survival highⁱ N/A
5-year survival lowⁱ N/A

TCGA RNA samplesⁱ

Average FPKM

3161.0

Number of samples

159

Samples

Sample	Description	FPKM
TCGA-DY-A1DF-01A	73 years, female, white, stage:iiic, dead, 734 days	10698.6
TCGA-AG-A032-01A	68 years, male, stage:iiib, alive, 1157 days	8719.8
TCGA-AG-A026-01A	66 years, male, stage:ii, dead, 59 days	8159.6
TCGA-DY-A1DD-01A	77 years, female, white, stage:iiib, dead, 1741 days	8095.6
TCGA-AF-A56K-01A	56 years, male, black or african american, stage:iia, alive, 2635 days	8039.1
TCGA-DY-A1H8-01A	77 years, female, white, stage:iiia, dead, 992 days	7809.8
TCGA-CL-5918-01A	90 years, female, white, stage:iia, alive, 218 days	7749.7
TCGA-BM-6198-01A	73 years, male, white, stage:iiib, alive, 646 days	7729.5
TCGA-AG-A002-01A	35 years, male, stage:i, alive, 638 days	7516.2
TCGA-F5-6812-01A	67 years, male, white, stage:iia, alive, 1110 days	7291.9
TCGA-AG-A011-01A	80 years, male, stage:iia, alive, 1126 days	6275.6
TCGA-AG-A02N-01A	67 years, male, stage:ii, alive, 1885 days	6089.9
TCGA-DY-A1DG-01A	75 years, male, white, stage:iva, dead, 1566 days	5940.6
TCGA-G5-6641-01A	67 years, male, white, stage:iiia, alive, 804 days	5924.3
TCGA-G5-6235-01A	72 years, male, white, stage:iiib, alive, 1696 days	5766.7
TCGA-AG-3898-01A	61 years, male, stage:iia, alive, 1461 days	5664.2
TCGA-F5-6571-01A	62 years, female, white, stage:iia, alive, 1288 days	5583.2
TCGA-AG-A015-01A	64 years, female, stage:i, alive, 1096 days	5511.9
TCGA-DY-A1DC-01A	72 years, female, white, stage:iia, dead, 1258 days	5430.4
TCGA-AG-3893-01A	74 years, male, stage:iiib, alive, 1065 days	5400.2
TCGA-AG-3732-01A	78 years, female, stage:i, alive, 1003 days	5274.8
TCGA-AG-3890-01A	62 years, male, stage:i, alive, 518 days	5120.7
TCGA-AG-A01J-01A	59 years, female, stage:iia, alive, 31 days	5016.5
TCGA-AH-6643-01A	50 years, male, white, stage:iiic, dead, 1314 days	4999.5
TCGA-CI-6624-01C	53 years, female, white, stage:i, alive, 1466 days	4846.2
TCGA-AG-3593-01A	72 years, female, stage:iia, alive, 1035 days	4845.3
TCGA-AG-A025-01A	62 years, female, stage:i, alive, 1520 days	4781.2
TCGA-EI-6514-01A	59 years, female, white, stage:iia, alive, 496 days	4723.8
TCGA-AG-A020-01A	57 years, female, stage:iii, alive, 31 days	4680.5
TCGA-EI-6509-01A	53 years, male, white, stage:iiic, alive, 517 days	4673.0
TCGA-EI-6510-01A	77 years, female, white, alive, 556 days	4569.1
TCGA-AF-2691-01A	48 years, female, white, stage:i, alive, 1309 days	4519.7
TCGA-EI-6881-01A	60 years, male, white, stage:iiia, alive, 499 days	4289.6
TCGA-AH-6544-01A	60 years, male, white, alive, 1173 days	4231.1
TCGA-CL-4957-01A	79 years, female, dead, 425 days	4224.5
TCGA-AG-A014-01A	86 years, male, stage:i, alive, 485 days	4152.1
TCGA-AG-3592-01A	68 years, male, stage:iia, alive, 1035 days	4130.8
TCGA-AG-3742-01A	85 years, female, stage:i, alive, 30 days	4086.9
TCGA-AG-A00H-01A	75 years, male, stage:iia, alive, 790 days	3922.2
TCGA-AG-A00C-01A	49 years, female, stage:iiib, alive, 183 days	3898.3
TCGA-EI-6513-01A	59 years, male, white, stage:iiib, alive, 497 days	3892.8
TCGA-AG-4008-01A	63 years, male, stage:iia, alive, 518 days	3858.8
TCGA-EI-6506-01A	78 years, female, white, stage:iia, alive, 625 days	3831.4
TCGA-AG-3578-01A	76 years, female, stage:iia, alive, 974 days	3792.9
TCGA-F5-6813-01A	70 years, male, white, stage:iiic, dead, 598 days	3758.0
TCGA-CI-6619-01B	41 years, male, white, stage:iv, alive, 184 days	3755.0
TCGA-G5-6572-01A	56 years, male, white, dead, 1432 days	3724.6
TCGA-AF-6672-01A	43 years, male, white, stage:iv, alive, 748 days	3721.4
TCGA-AH-6547-01A	79 years, female, white, dead, 76 days	3694.8
TCGA-DY-A0XA-01A	57 years, female, white, stage:iia, alive, 3846 days	3670.3
TCGA-G5-6233-01A	74 years, male, white, dead, 556 days	3638.2
TCGA-AG-A023-01A	62 years, female, stage:iv, dead, 1581 days	3630.2
TCGA-AG-A01N-01A	68 years, female, stage:iv, alive, 943 days	3621.0
TCGA-AG-4022-01A	59 years, female, stage:ii, alive, 1400 days	3612.3
TCGA-DC-6682-01A	57 years, male, white, stage:iia, alive, 762 days	3508.2
TCGA-AG-4001-01A	74 years, female, stage:iia, alive, 1096 days	3502.2
TCGA-AG-A02X-01A	77 years, male, stage:i, alive, 1247 days	3478.5
TCGA-AF-3911-01A	48 years, male, white, stage:iiic, alive, 1148 days	3450.4
TCGA-EF-5831-01A	72 years, male, white, stage:iia, alive, 127 days	3425.2
TCGA-AG-3584-01A	60 years, male, stage:iv, dead, 730 days	3398.6
TCGA-F5-6702-01A	71 years, male, white, stage:iva, alive, 869 days	3354.3
TCGA-AG-3725-01A	90 years, female, stage:iii, alive, 638 days	3345.9
TCGA-AG-A02G-01A	66 years, male, stage:iv, dead, 1185 days	3248.4
TCGA-CI-6621-01A	63 years, male, white, stage:iiib, alive, 419 days	3247.9
TCGA-AG-3594-01A	77 years, male, stage:iia, dead, 61 days	3170.2
TCGA-AG-3580-01A	67 years, male, stage:i, alive, 244 days	3150.0
TCGA-F5-6811-01A	72 years, female, white, stage:iia, alive, 979 days	3145.4
TCGA-AG-3901-01A	67 years, female, stage:iiib, alive, 761 days	3095.6
TCGA-AG-3612-01A	55 years, female, stage:iiib, alive, 608 days	3093.2
TCGA-AG-3999-01A	61 years, female, stage:iiic, alive, 853 days	3064.7
TCGA-CI-6623-01B	44 years, male, white, stage:i, alive, 1443 days	3029.8
TCGA-AG-3583-01A	66 years, male, stage:iv, dead, 610 days	3014.4
TCGA-CI-6620-01A	41 years, female, white, stage:iva, alive, 1009 days	3004.8
TCGA-EI-6512-01A	64 years, female, white, stage:iiib, alive, 538 days	2977.0
TCGA-AG-A00Y-01A	68 years, male, stage:iia, alive, 700 days	2974.0
TCGA-AF-2687-01A	57 years, male, white, stage:iiic, alive, 1427 days	2947.9
TCGA-AG-3600-01A	62 years, male, stage:iiic, alive, 184 days	2938.7
TCGA-AG-A008-01A	50 years, female, stage:i, alive, 424 days	2928.4
TCGA-AG-3909-01A	69 years, female, stage:iiib, alive, 608 days	2921.3
TCGA-AG-A036-01A	71 years, male, stage:iii, alive, 3562 days	2916.5
TCGA-AG-3582-01A	75 years, male, stage:iv, dead, 1096 days	2862.8
TCGA-AG-A016-01A	55 years, male, stage:iv, alive, 276 days	2828.5
TCGA-AG-3611-01A	72 years, male, stage:iia, alive, 424 days	2810.0
TCGA-AG-4005-01A	64 years, male, stage:iv, alive, 427 days	2799.8
TCGA-EF-5830-01A	54 years, male, white, stage:iib, alive, 106 days	2703.1
TCGA-AG-4021-01A	84 years, female, stage:iv, dead, 121 days	2685.3
TCGA-CI-6622-01A	74 years, male, white, stage:iib, alive, 1362 days	2682.0
TCGA-EI-6511-01A	52 years, male, white, stage:iiib, alive, 482 days	2673.4
TCGA-AF-4110-01A	77 years, male, white, stage:iva, alive, 912 days	2576.4
TCGA-DC-6683-01A	43 years, male, white, stage:iiib, alive, 762 days	2568.1
TCGA-F5-6464-01A	77 years, female, white, stage:iiic, dead, 303 days	2532.3
TCGA-AF-2692-01A	54 years, female, white, stage:iia, alive, 412 days	2528.1
TCGA-AG-3591-01A	66 years, female, stage:iia, alive, 1035 days	2521.5
TCGA-AF-A56N-01A	47 years, female, black or african american, stage:iia, alive, 360 days	2510.1
TCGA-AG-3896-01A	85 years, female, stage:i, alive, 31 days	2498.5
TCGA-AG-3731-01A	65 years, male, stage:iv, alive, 1126 days	2495.0
TCGA-CL-5917-01A	71 years, female, white, stage:iiic, alive, 2376 days	2493.5
TCGA-EI-6508-01A	48 years, female, white, stage:iiib, alive, 636 days	2445.6
TCGA-AG-3574-01A	89 years, female, stage:ii, dead, 1096 days	2440.3
TCGA-F5-6465-01A	64 years, female, white, stage:iia, alive, 1506 days	2416.6
TCGA-AG-4007-01A	87 years, male, stage:iv, alive, 31 days	2410.2
TCGA-AG-3586-01A	72 years, female, stage:iii, alive, 31 days	2351.4
TCGA-AF-2690-01A	77 years, female, white, stage:iiic, dead, 524 days	2344.6
TCGA-AF-5654-01A	73 years, female, white, stage:i, dead, 512 days	2311.2
TCGA-AH-6549-01A	66 years, male, white, alive, 532 days	2307.6
TCGA-DY-A1DE-01A	56 years, female, white, stage:iia, alive, 3932 days	2303.8
TCGA-AG-3887-01A	68 years, male, stage:iia, alive, 1124 days	2293.7
TCGA-AF-6655-01A	66 years, male, white, stage:iiia, alive, 609 days	2265.6
TCGA-AH-6903-01A	46 years, male, white, stage:iiib, alive, 592 days	2264.6
TCGA-AG-3581-01A	63 years, male, stage:i, alive, 215 days	2232.0
TCGA-DC-4749-01A	57 years, male, white, stage:i, alive, 762 days	2223.1
TCGA-AH-6644-01A	73 years, male, white, alive, 838 days	2183.4
TCGA-AF-2693-01A	75 years, male, white, stage:i, alive, 1155 days	2152.5
TCGA-AG-3894-01A	65 years, male, stage:iia, alive, 426 days	2140.3
TCGA-AG-3882-01A	66 years, female, stage:i, alive, 608 days	2138.2
TCGA-DC-6160-01A	68 years, male, white, stage:i, alive, 1339 days	2130.9
TCGA-AF-6136-01A	72 years, female, white, stage:iiib, alive, 741 days	2123.4
TCGA-AG-3599-01A	70 years, male, stage:i, alive, 366 days	2008.0
TCGA-AF-A56L-01A	48 years, female, black or african american, stage:iiic, alive, 2007 days	2006.3
TCGA-AG-3608-01A	79 years, female, stage:iia, alive, 485 days	1956.5
TCGA-DT-5265-01A	51 years, male, asian, stage:ii, alive, 384 days	1940.1
TCGA-AG-3902-01A	61 years, male, stage:iia, alive, 974 days	1915.2
TCGA-AG-3598-01A	69 years, male, stage:iia, alive, 1522 days	1872.8
TCGA-DC-6157-01A	48 years, male, black or african american, stage:i, alive, 1581 days	1849.6
TCGA-DC-6156-01A	62 years, male, white, stage:iva, alive, 943 days	1844.1
TCGA-AG-3605-01A	85 years, female, stage:iv, alive, 30 days	1711.7
TCGA-F5-6861-01A	60 years, female, white, stage:iia, alive, 1160 days	1684.1
TCGA-AG-3892-01A	57 years, female, stage:i, alive, 396 days	1666.0
TCGA-DC-6158-01A	70 years, male, white, stage:i, dead, 334 days	1652.8
TCGA-AG-3587-01A	65 years, male, stage:i, alive, 1400 days	1623.6
TCGA-AF-3913-01A	60 years, male, black or african american, stage:iv, dead, 316 days	1572.0
TCGA-F5-6814-01A	57 years, male, white, stage:iia, alive, 1131 days	1555.4
TCGA-AF-3400-01A	54 years, male, white, stage:iia, alive, 1049 days	1544.1
TCGA-DC-6681-01A	70 years, female, white, stage:iva, alive, 790 days	1534.0
TCGA-EI-6507-01A	60 years, male, white, stage:iia, alive, 607 days	1428.8
TCGA-F5-6864-01A	74 years, female, white, stage:iiib, alive, 379 days	1289.6
TCGA-AG-3878-01A	64 years, male, stage:i, alive, 30 days	1242.2
TCGA-DC-4745-01A	49 years, female, white, stage:iiib, alive, 639 days	1142.9
TCGA-F5-6863-01A	71 years, female, white, stage:iiib, dead, 361 days	1038.0
TCGA-AG-3609-01A	65 years, female, stage:iiic, alive, 608 days	971.3
TCGA-EI-6883-01A	63 years, male, white, stage:iic, alive, 350 days	890.3
TCGA-EI-6885-01A	57 years, female, white, stage:iv, alive, 415 days	830.9
TCGA-EI-6882-01A	59 years, male, white, stage:iia, alive, 262 days	738.8
TCGA-AG-3728-01A	73 years, male, stage:iiib, alive, 912 days	704.8
TCGA-AH-6897-01A	48 years, male, white, stage:i, alive, 804 days	693.9
TCGA-EI-6917-01A	33 years, male, white, stage:iiia, alive, 531 days	663.3
TCGA-AG-3575-01A	51 years, male, stage:ii, alive, 365 days	643.4
TCGA-AG-3883-01A	69 years, male, stage:i, alive, 31 days	642.4
TCGA-EI-7002-01A	58 years, male, white, stage:iv, alive, 364 days	619.3
TCGA-DC-5337-01A	69 years, male, white, stage:i, alive, 792 days	603.8
TCGA-AG-3885-01A	71 years, female, stage:iiib, alive, 546 days	588.7
TCGA-DC-5869-01A	62 years, female, black or african american, stage:iiib, alive, 943 days	532.0
TCGA-DC-6154-01A	57 years, female, white, stage:iva, alive, 365 days	437.1
TCGA-AG-3881-01A	83 years, female, stage:iia, alive, 579 days	434.2
TCGA-EI-6884-01A	71 years, male, white, stage:iiia, alive, 328 days	414.3
TCGA-EI-7004-01A	37 years, female, white, alive, 257 days	358.7
TCGA-AG-3727-01A	78 years, female, stage:iii, alive, 30 days	256.4
TCGA-AG-3726-01A	63 years, female, stage:i, alive, 243 days	239.8
TCGA-DC-6155-01A	31 years, female, white, stage:iiia, alive, 425 days	105.5
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