Expression of S100A11 in colorectal cancer

RECTUM ADENOCARCINOMA (READ) - Interactive survival scatter plotⁱ

The Survival Scatter plot shows the clinical status (i.e. dead or alive) for all individuals in the patient cohort, based on the same data that underlies the corresponding Kaplan-Meier plots. Patients that are alive at last time for follow-up are shown in blue and patients who have died during the study are shown in red.

The x-axis shows the expression levels (FPKM) of the investigated gene in the tumor tissue at the time of diagnosis. The y-axis shows the follow-up time after diagnosis (years). Both axes are complimented with kernel density curves demonstrating the data density over the axes. The top density plot shows the expression levels (FPKM) distribution among dead (red) and alive patients (blue). The right density plot shows the data density of the survived years of dead patients with high and low expression levels respectively, stratified using the cutoff indicated by the vertical dashed line through the Survival Scatter plot. This cutoff is automatically defined based on the FPKM cutoff that minimizes the p-score. The cutoff can be changed by dragging the vertical line or by entering a cutoff value in the square labeled "Current cut-off".

Under the Survival Scatter plot the p-score landscape (black curve; left axis) is shown together with dead median separation (red curve; right axis). Dead median separation is the difference in median mRNA expression between patients who have died with high and low expression, respectively. It is calculated as follows: median FPKM expression of dead patients with high expression - median FPKM expression of dead patients with low expression. This is intended to aid the user in visually exploring custom cutoffs and the associated p-scores and dead median separation.

Individual patient data is displayed and can be filtered by clicking on one or more of the category buttons on the top of the page. Categories describing expression level and patient information include: high, low, alive, dead, female, male and tumor stages. The scale of the x-axis can be toggled between linear and log-scale by clicking on the "x log" button. Mouse-over function shows TCGA ID, patient information and mRNA expression (FPKM) for each patient.

& Survival analysisⁱ

Stage:

Survival analysis

Current cut offⁱ:
Best expression cut offⁱ: 717.12
Median expressionⁱ: N/A
Median follow up timeⁱ: N/A
P scoreⁱ N/A
5-year survival highⁱ N/A
5-year survival lowⁱ N/A

TCGA RNA samplesⁱ

Average FPKM

685.1

Number of samples

159

Samples

Sample	Description	FPKM
TCGA-AG-3575-01A	51 years, male, stage:ii, alive, 365 days	2679.8
TCGA-BM-6198-01A	73 years, male, white, stage:iiib, alive, 646 days	1957.0
TCGA-AH-6643-01A	50 years, male, white, stage:iiic, dead, 1314 days	1774.9
TCGA-F5-6464-01A	77 years, female, white, stage:iiic, dead, 303 days	1669.8
TCGA-AG-3999-01A	61 years, female, stage:iiic, alive, 853 days	1565.7
TCGA-DT-5265-01A	51 years, male, asian, stage:ii, alive, 384 days	1526.7
TCGA-AG-3609-01A	65 years, female, stage:iiic, alive, 608 days	1349.8
TCGA-AG-3578-01A	76 years, female, stage:iia, alive, 974 days	1239.8
TCGA-DC-6155-01A	31 years, female, white, stage:iiia, alive, 425 days	1169.9
TCGA-AG-3611-01A	72 years, male, stage:iia, alive, 424 days	1154.3
TCGA-AG-3583-01A	66 years, male, stage:iv, dead, 610 days	1148.9
TCGA-EI-6881-01A	60 years, male, white, stage:iiia, alive, 499 days	1137.6
TCGA-F5-6813-01A	70 years, male, white, stage:iiic, dead, 598 days	1092.4
TCGA-AG-A032-01A	68 years, male, stage:iiib, alive, 1157 days	1086.3
TCGA-AG-3881-01A	83 years, female, stage:iia, alive, 579 days	1065.7
TCGA-AH-6544-01A	60 years, male, white, alive, 1173 days	1053.2
TCGA-AF-2692-01A	54 years, female, white, stage:iia, alive, 412 days	1047.5
TCGA-AG-3580-01A	67 years, male, stage:i, alive, 244 days	1031.0
TCGA-AG-3599-01A	70 years, male, stage:i, alive, 366 days	1018.1
TCGA-AG-3591-01A	66 years, female, stage:iia, alive, 1035 days	1010.9
TCGA-AG-A00H-01A	75 years, male, stage:iia, alive, 790 days	983.4
TCGA-AG-3725-01A	90 years, female, stage:iii, alive, 638 days	949.0
TCGA-AG-3894-01A	65 years, male, stage:iia, alive, 426 days	941.1
TCGA-AH-6644-01A	73 years, male, white, alive, 838 days	934.2
TCGA-AF-2693-01A	75 years, male, white, stage:i, alive, 1155 days	928.0
TCGA-AG-3593-01A	72 years, female, stage:iia, alive, 1035 days	927.2
TCGA-CL-5918-01A	90 years, female, white, stage:iia, alive, 218 days	921.4
TCGA-AG-3600-01A	62 years, male, stage:iiic, alive, 184 days	905.9
TCGA-AG-3598-01A	69 years, male, stage:iia, alive, 1522 days	899.8
TCGA-AG-A026-01A	66 years, male, stage:ii, dead, 59 days	897.8
TCGA-AF-6672-01A	43 years, male, white, stage:iv, alive, 748 days	897.4
TCGA-DC-5337-01A	69 years, male, white, stage:i, alive, 792 days	884.3
TCGA-DY-A1DF-01A	73 years, female, white, stage:iiic, dead, 734 days	882.3
TCGA-AG-A015-01A	64 years, female, stage:i, alive, 1096 days	878.9
TCGA-AG-3892-01A	57 years, female, stage:i, alive, 396 days	874.8
TCGA-AG-4005-01A	64 years, male, stage:iv, alive, 427 days	874.3
TCGA-DY-A1DG-01A	75 years, male, white, stage:iva, dead, 1566 days	854.1
TCGA-AG-3898-01A	61 years, male, stage:iia, alive, 1461 days	845.5
TCGA-DY-A1DC-01A	72 years, female, white, stage:iia, dead, 1258 days	817.5
TCGA-DY-A1H8-01A	77 years, female, white, stage:iiia, dead, 992 days	815.0
TCGA-AG-3574-01A	89 years, female, stage:ii, dead, 1096 days	812.1
TCGA-AG-A002-01A	35 years, male, stage:i, alive, 638 days	803.2
TCGA-AF-3400-01A	54 years, male, white, stage:iia, alive, 1049 days	787.9
TCGA-AG-A02X-01A	77 years, male, stage:i, alive, 1247 days	766.1
TCGA-AG-4021-01A	84 years, female, stage:iv, dead, 121 days	754.4
TCGA-AG-3902-01A	61 years, male, stage:iia, alive, 974 days	751.4
TCGA-AG-3586-01A	72 years, female, stage:iii, alive, 31 days	733.7
TCGA-AG-3594-01A	77 years, male, stage:iia, dead, 61 days	724.7
TCGA-AG-A01N-01A	68 years, female, stage:iv, alive, 943 days	724.4
TCGA-G5-6233-01A	74 years, male, white, dead, 556 days	721.6
TCGA-AG-3582-01A	75 years, male, stage:iv, dead, 1096 days	718.8
TCGA-AG-A00Y-01A	68 years, male, stage:iia, alive, 700 days	715.4
TCGA-EF-5830-01A	54 years, male, white, stage:iib, alive, 106 days	713.4
TCGA-AF-4110-01A	77 years, male, white, stage:iva, alive, 912 days	700.9
TCGA-G5-6641-01A	67 years, male, white, stage:iiia, alive, 804 days	695.0
TCGA-EF-5831-01A	72 years, male, white, stage:iia, alive, 127 days	686.1
TCGA-AF-3911-01A	48 years, male, white, stage:iiic, alive, 1148 days	678.7
TCGA-AG-A01J-01A	59 years, female, stage:iia, alive, 31 days	667.1
TCGA-AF-A56N-01A	47 years, female, black or african american, stage:iia, alive, 360 days	666.0
TCGA-DC-6160-01A	68 years, male, white, stage:i, alive, 1339 days	664.0
TCGA-AG-A00C-01A	49 years, female, stage:iiib, alive, 183 days	660.9
TCGA-CI-6623-01B	44 years, male, white, stage:i, alive, 1443 days	660.5
TCGA-AG-4008-01A	63 years, male, stage:iia, alive, 518 days	658.7
TCGA-F5-6812-01A	67 years, male, white, stage:iia, alive, 1110 days	646.3
TCGA-AG-3878-01A	64 years, male, stage:i, alive, 30 days	644.7
TCGA-AG-3581-01A	63 years, male, stage:i, alive, 215 days	644.2
TCGA-AG-3612-01A	55 years, female, stage:iiib, alive, 608 days	636.0
TCGA-AG-3896-01A	85 years, female, stage:i, alive, 31 days	634.3
TCGA-AG-A008-01A	50 years, female, stage:i, alive, 424 days	633.9
TCGA-AG-3901-01A	67 years, female, stage:iiib, alive, 761 days	631.8
TCGA-DC-6156-01A	62 years, male, white, stage:iva, alive, 943 days	626.9
TCGA-AG-3742-01A	85 years, female, stage:i, alive, 30 days	625.8
TCGA-DC-6158-01A	70 years, male, white, stage:i, dead, 334 days	622.0
TCGA-AG-3584-01A	60 years, male, stage:iv, dead, 730 days	620.6
TCGA-EI-6507-01A	60 years, male, white, stage:iia, alive, 607 days	617.3
TCGA-DY-A1DE-01A	56 years, female, white, stage:iia, alive, 3932 days	616.3
TCGA-AG-3587-01A	65 years, male, stage:i, alive, 1400 days	614.3
TCGA-AG-3893-01A	74 years, male, stage:iiib, alive, 1065 days	612.6
TCGA-AG-3728-01A	73 years, male, stage:iiib, alive, 912 days	609.6
TCGA-CI-6619-01B	41 years, male, white, stage:iv, alive, 184 days	609.4
TCGA-AG-A014-01A	86 years, male, stage:i, alive, 485 days	608.2
TCGA-AF-3913-01A	60 years, male, black or african american, stage:iv, dead, 316 days	606.3
TCGA-F5-6702-01A	71 years, male, white, stage:iva, alive, 869 days	602.5
TCGA-AH-6549-01A	66 years, male, white, alive, 532 days	600.8
TCGA-AG-4007-01A	87 years, male, stage:iv, alive, 31 days	597.9
TCGA-DC-5869-01A	62 years, female, black or african american, stage:iiib, alive, 943 days	594.8
TCGA-AG-A02N-01A	67 years, male, stage:ii, alive, 1885 days	586.5
TCGA-AG-3605-01A	85 years, female, stage:iv, alive, 30 days	581.3
TCGA-AG-3909-01A	69 years, female, stage:iiib, alive, 608 days	580.8
TCGA-CI-6622-01A	74 years, male, white, stage:iib, alive, 1362 days	575.6
TCGA-CL-4957-01A	79 years, female, dead, 425 days	575.5
TCGA-AF-2687-01A	57 years, male, white, stage:iiic, alive, 1427 days	572.9
TCGA-CI-6621-01A	63 years, male, white, stage:iiib, alive, 419 days	572.9
TCGA-EI-6512-01A	64 years, female, white, stage:iiib, alive, 538 days	570.2
TCGA-AF-6136-01A	72 years, female, white, stage:iiib, alive, 741 days	560.5
TCGA-CI-6620-01A	41 years, female, white, stage:iva, alive, 1009 days	559.2
TCGA-AG-3883-01A	69 years, male, stage:i, alive, 31 days	558.3
TCGA-F5-6861-01A	60 years, female, white, stage:iia, alive, 1160 days	557.6
TCGA-AG-A036-01A	71 years, male, stage:iii, alive, 3562 days	556.9
TCGA-F5-6811-01A	72 years, female, white, stage:iia, alive, 979 days	553.9
TCGA-DY-A1DD-01A	77 years, female, white, stage:iiib, dead, 1741 days	552.7
TCGA-F5-6863-01A	71 years, female, white, stage:iiib, dead, 361 days	549.5
TCGA-AG-A020-01A	57 years, female, stage:iii, alive, 31 days	541.9
TCGA-AG-4001-01A	74 years, female, stage:iia, alive, 1096 days	540.8
TCGA-AG-3592-01A	68 years, male, stage:iia, alive, 1035 days	539.5
TCGA-DC-6681-01A	70 years, female, white, stage:iva, alive, 790 days	534.9
TCGA-EI-6509-01A	53 years, male, white, stage:iiic, alive, 517 days	529.3
TCGA-AG-3882-01A	66 years, female, stage:i, alive, 608 days	515.1
TCGA-EI-6511-01A	52 years, male, white, stage:iiib, alive, 482 days	512.9
TCGA-AF-6655-01A	66 years, male, white, stage:iiia, alive, 609 days	507.8
TCGA-EI-6513-01A	59 years, male, white, stage:iiib, alive, 497 days	505.3
TCGA-DC-4749-01A	57 years, male, white, stage:i, alive, 762 days	498.6
TCGA-AG-3608-01A	79 years, female, stage:iia, alive, 485 days	495.0
TCGA-AF-2690-01A	77 years, female, white, stage:iiic, dead, 524 days	492.0
TCGA-EI-6882-01A	59 years, male, white, stage:iia, alive, 262 days	491.6
TCGA-DC-6683-01A	43 years, male, white, stage:iiib, alive, 762 days	487.3
TCGA-EI-6508-01A	48 years, female, white, stage:iiib, alive, 636 days	483.9
TCGA-AF-5654-01A	73 years, female, white, stage:i, dead, 512 days	481.6
TCGA-AF-A56L-01A	48 years, female, black or african american, stage:iiic, alive, 2007 days	481.0
TCGA-EI-6506-01A	78 years, female, white, stage:iia, alive, 625 days	479.2
TCGA-CI-6624-01C	53 years, female, white, stage:i, alive, 1466 days	475.7
TCGA-EI-6514-01A	59 years, female, white, stage:iia, alive, 496 days	474.7
TCGA-AF-2691-01A	48 years, female, white, stage:i, alive, 1309 days	472.4
TCGA-AH-6903-01A	46 years, male, white, stage:iiib, alive, 592 days	468.4
TCGA-AG-A025-01A	62 years, female, stage:i, alive, 1520 days	467.4
TCGA-EI-6884-01A	71 years, male, white, stage:iiia, alive, 328 days	467.0
TCGA-DY-A0XA-01A	57 years, female, white, stage:iia, alive, 3846 days	464.6
TCGA-AG-A023-01A	62 years, female, stage:iv, dead, 1581 days	464.4
TCGA-AG-3885-01A	71 years, female, stage:iiib, alive, 546 days	462.0
TCGA-DC-4745-01A	49 years, female, white, stage:iiib, alive, 639 days	454.3
TCGA-G5-6235-01A	72 years, male, white, stage:iiib, alive, 1696 days	452.0
TCGA-AG-3887-01A	68 years, male, stage:iia, alive, 1124 days	450.8
TCGA-AG-A016-01A	55 years, male, stage:iv, alive, 276 days	436.3
TCGA-AG-4022-01A	59 years, female, stage:ii, alive, 1400 days	422.2
TCGA-EI-6917-01A	33 years, male, white, stage:iiia, alive, 531 days	417.0
TCGA-EI-6510-01A	77 years, female, white, alive, 556 days	416.2
TCGA-CL-5917-01A	71 years, female, white, stage:iiic, alive, 2376 days	413.5
TCGA-AG-3890-01A	62 years, male, stage:i, alive, 518 days	409.3
TCGA-DC-6154-01A	57 years, female, white, stage:iva, alive, 365 days	409.1
TCGA-AH-6897-01A	48 years, male, white, stage:i, alive, 804 days	405.0
TCGA-AF-A56K-01A	56 years, male, black or african american, stage:iia, alive, 2635 days	403.7
TCGA-F5-6814-01A	57 years, male, white, stage:iia, alive, 1131 days	400.1
TCGA-DC-6682-01A	57 years, male, white, stage:iia, alive, 762 days	399.2
TCGA-EI-7002-01A	58 years, male, white, stage:iv, alive, 364 days	390.1
TCGA-AG-A02G-01A	66 years, male, stage:iv, dead, 1185 days	381.8
TCGA-F5-6571-01A	62 years, female, white, stage:iia, alive, 1288 days	362.7
TCGA-AG-3731-01A	65 years, male, stage:iv, alive, 1126 days	360.3
TCGA-F5-6465-01A	64 years, female, white, stage:iia, alive, 1506 days	359.5
TCGA-AG-3726-01A	63 years, female, stage:i, alive, 243 days	354.7
TCGA-AG-A011-01A	80 years, male, stage:iia, alive, 1126 days	338.5
TCGA-G5-6572-01A	56 years, male, white, dead, 1432 days	336.9
TCGA-EI-6885-01A	57 years, female, white, stage:iv, alive, 415 days	334.9
TCGA-AH-6547-01A	79 years, female, white, dead, 76 days	328.7
TCGA-AG-3732-01A	78 years, female, stage:i, alive, 1003 days	311.9
TCGA-AG-3727-01A	78 years, female, stage:iii, alive, 30 days	286.3
TCGA-EI-7004-01A	37 years, female, white, alive, 257 days	280.8
TCGA-EI-6883-01A	63 years, male, white, stage:iic, alive, 350 days	279.4
TCGA-DC-6157-01A	48 years, male, black or african american, stage:i, alive, 1581 days	271.3
TCGA-F5-6864-01A	74 years, female, white, stage:iiib, alive, 379 days	266.1
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