Expression of MT-CO2 in colorectal cancer

RECTUM ADENOCARCINOMA (READ) - Interactive survival scatter plotⁱ

The Survival Scatter plot shows the clinical status (i.e. dead or alive) for all individuals in the patient cohort, based on the same data that underlies the corresponding Kaplan-Meier plots. Patients that are alive at last time for follow-up are shown in blue and patients who have died during the study are shown in red.

The x-axis shows the expression levels (FPKM) of the investigated gene in the tumor tissue at the time of diagnosis. The y-axis shows the follow-up time after diagnosis (years). Both axes are complimented with kernel density curves demonstrating the data density over the axes. The top density plot shows the expression levels (FPKM) distribution among dead (red) and alive patients (blue). The right density plot shows the data density of the survived years of dead patients with high and low expression levels respectively, stratified using the cutoff indicated by the vertical dashed line through the Survival Scatter plot. This cutoff is automatically defined based on the FPKM cutoff that minimizes the p-score. The cutoff can be changed by dragging the vertical line or by entering a cutoff value in the square labeled "Current cut-off".

Under the Survival Scatter plot the p-score landscape (black curve; left axis) is shown together with dead median separation (red curve; right axis). Dead median separation is the difference in median mRNA expression between patients who have died with high and low expression, respectively. It is calculated as follows: median FPKM expression of dead patients with high expression - median FPKM expression of dead patients with low expression. This is intended to aid the user in visually exploring custom cutoffs and the associated p-scores and dead median separation.

Individual patient data is displayed and can be filtered by clicking on one or more of the category buttons on the top of the page. Categories describing expression level and patient information include: high, low, alive, dead, female, male and tumor stages. The scale of the x-axis can be toggled between linear and log-scale by clicking on the "x log" button. Mouse-over function shows TCGA ID, patient information and mRNA expression (FPKM) for each patient.

& Survival analysisⁱ

Stage:

Survival analysis

Current cut offⁱ:
Best expression cut offⁱ: 13871.18
Median expressionⁱ: N/A
Median follow up timeⁱ: N/A
P scoreⁱ N/A
5-year survival highⁱ N/A
5-year survival lowⁱ N/A

TCGA RNA samplesⁱ

Average FPKM

11904.0

Number of samples

159

Samples

Sample	Description	FPKM
TCGA-DY-A1DF-01A	73 years, female, white, stage:iiic, dead, 734 days	76124.4
TCGA-DY-A1H8-01A	77 years, female, white, stage:iiia, dead, 992 days	36214.4
TCGA-BM-6198-01A	73 years, male, white, stage:iiib, alive, 646 days	34036.7
TCGA-DY-A1DD-01A	77 years, female, white, stage:iiib, dead, 1741 days	31207.5
TCGA-F5-6812-01A	67 years, male, white, stage:iia, alive, 1110 days	29923.6
TCGA-AG-A026-01A	66 years, male, stage:ii, dead, 59 days	26778.4
TCGA-AG-A01J-01A	59 years, female, stage:iia, alive, 31 days	25823.5
TCGA-AF-A56K-01A	56 years, male, black or african american, stage:iia, alive, 2635 days	25234.5
TCGA-AG-A011-01A	80 years, male, stage:iia, alive, 1126 days	25145.9
TCGA-CL-5918-01A	90 years, female, white, stage:iia, alive, 218 days	23507.2
TCGA-F5-6571-01A	62 years, female, white, stage:iia, alive, 1288 days	23390.1
TCGA-DY-A1DG-01A	75 years, male, white, stage:iva, dead, 1566 days	21989.3
TCGA-EI-6514-01A	59 years, female, white, stage:iia, alive, 496 days	21811.4
TCGA-DY-A1DC-01A	72 years, female, white, stage:iia, dead, 1258 days	20246.1
TCGA-AG-3592-01A	68 years, male, stage:iia, alive, 1035 days	20052.7
TCGA-AH-6544-01A	60 years, male, white, alive, 1173 days	19972.3
TCGA-CI-6624-01C	53 years, female, white, stage:i, alive, 1466 days	19529.3
TCGA-G5-6235-01A	72 years, male, white, stage:iiib, alive, 1696 days	19143.4
TCGA-AG-A00H-01A	75 years, male, stage:iia, alive, 790 days	19134.0
TCGA-AG-A014-01A	86 years, male, stage:i, alive, 485 days	18494.5
TCGA-AG-A015-01A	64 years, female, stage:i, alive, 1096 days	18133.1
TCGA-AG-3583-01A	66 years, male, stage:iv, dead, 610 days	17593.2
TCGA-AG-3593-01A	72 years, female, stage:iia, alive, 1035 days	17408.0
TCGA-AG-3882-01A	66 years, female, stage:i, alive, 608 days	17375.9
TCGA-AG-A032-01A	68 years, male, stage:iiib, alive, 1157 days	17112.3
TCGA-AG-3898-01A	61 years, male, stage:iia, alive, 1461 days	16377.8
TCGA-AG-A002-01A	35 years, male, stage:i, alive, 638 days	15882.9
TCGA-AG-3586-01A	72 years, female, stage:iii, alive, 31 days	15869.9
TCGA-AG-A02N-01A	67 years, male, stage:ii, alive, 1885 days	15834.8
TCGA-EI-6510-01A	77 years, female, white, alive, 556 days	15659.7
TCGA-AG-3581-01A	63 years, male, stage:i, alive, 215 days	15455.0
TCGA-AF-2692-01A	54 years, female, white, stage:iia, alive, 412 days	15450.7
TCGA-AG-A036-01A	71 years, male, stage:iii, alive, 3562 days	15077.9
TCGA-G5-6233-01A	74 years, male, white, dead, 556 days	14888.1
TCGA-AF-2691-01A	48 years, female, white, stage:i, alive, 1309 days	14883.6
TCGA-AG-3732-01A	78 years, female, stage:i, alive, 1003 days	14879.0
TCGA-G5-6572-01A	56 years, male, white, dead, 1432 days	14839.7
TCGA-F5-6813-01A	70 years, male, white, stage:iiic, dead, 598 days	14782.8
TCGA-AG-3890-01A	62 years, male, stage:i, alive, 518 days	14559.4
TCGA-AG-3584-01A	60 years, male, stage:iv, dead, 730 days	14553.7
TCGA-AH-6547-01A	79 years, female, white, dead, 76 days	14439.3
TCGA-G5-6641-01A	67 years, male, white, stage:iiia, alive, 804 days	14316.3
TCGA-EF-5831-01A	72 years, male, white, stage:iia, alive, 127 days	13987.5
TCGA-AG-3893-01A	74 years, male, stage:iiib, alive, 1065 days	13879.9
TCGA-AF-5654-01A	73 years, female, white, stage:i, dead, 512 days	13874.8
TCGA-AG-A025-01A	62 years, female, stage:i, alive, 1520 days	13867.5
TCGA-AG-A01N-01A	68 years, female, stage:iv, alive, 943 days	13719.4
TCGA-AG-3578-01A	76 years, female, stage:iia, alive, 974 days	13691.6
TCGA-EI-6513-01A	59 years, male, white, stage:iiib, alive, 497 days	13580.3
TCGA-AG-3612-01A	55 years, female, stage:iiib, alive, 608 days	13419.6
TCGA-AG-4022-01A	59 years, female, stage:ii, alive, 1400 days	13335.6
TCGA-CI-6619-01B	41 years, male, white, stage:iv, alive, 184 days	13288.7
TCGA-EI-6509-01A	53 years, male, white, stage:iiic, alive, 517 days	13164.6
TCGA-AG-A00C-01A	49 years, female, stage:iiib, alive, 183 days	13132.4
TCGA-AG-3574-01A	89 years, female, stage:ii, dead, 1096 days	12967.9
TCGA-AG-A023-01A	62 years, female, stage:iv, dead, 1581 days	12886.5
TCGA-DY-A1DE-01A	56 years, female, white, stage:iia, alive, 3932 days	12386.9
TCGA-AG-A016-01A	55 years, male, stage:iv, alive, 276 days	12369.0
TCGA-AF-6672-01A	43 years, male, white, stage:iv, alive, 748 days	12329.5
TCGA-CI-6623-01B	44 years, male, white, stage:i, alive, 1443 days	12290.0
TCGA-AF-3911-01A	48 years, male, white, stage:iiic, alive, 1148 days	12120.7
TCGA-EI-6881-01A	60 years, male, white, stage:iiia, alive, 499 days	12111.2
TCGA-AG-3600-01A	62 years, male, stage:iiic, alive, 184 days	11630.7
TCGA-AG-3878-01A	64 years, male, stage:i, alive, 30 days	11492.8
TCGA-AH-6643-01A	50 years, male, white, stage:iiic, dead, 1314 days	11465.6
TCGA-AG-3742-01A	85 years, female, stage:i, alive, 30 days	11426.6
TCGA-EI-6506-01A	78 years, female, white, stage:iia, alive, 625 days	11410.5
TCGA-AG-A00Y-01A	68 years, male, stage:iia, alive, 700 days	11399.0
TCGA-EF-5830-01A	54 years, male, white, stage:iib, alive, 106 days	11307.0
TCGA-DY-A0XA-01A	57 years, female, white, stage:iia, alive, 3846 days	11244.2
TCGA-AG-3725-01A	90 years, female, stage:iii, alive, 638 days	11226.4
TCGA-AG-3580-01A	67 years, male, stage:i, alive, 244 days	11192.7
TCGA-AG-4001-01A	74 years, female, stage:iia, alive, 1096 days	11174.7
TCGA-CI-6621-01A	63 years, male, white, stage:iiib, alive, 419 days	10824.9
TCGA-AG-3999-01A	61 years, female, stage:iiic, alive, 853 days	10776.0
TCGA-AH-6903-01A	46 years, male, white, stage:iiib, alive, 592 days	10487.3
TCGA-AG-3909-01A	69 years, female, stage:iiib, alive, 608 days	10357.2
TCGA-CL-4957-01A	79 years, female, dead, 425 days	10318.2
TCGA-CI-6620-01A	41 years, female, white, stage:iva, alive, 1009 days	10159.6
TCGA-AG-3883-01A	69 years, male, stage:i, alive, 31 days	10069.1
TCGA-AG-3605-01A	85 years, female, stage:iv, alive, 30 days	9966.6
TCGA-AG-3582-01A	75 years, male, stage:iv, dead, 1096 days	9902.6
TCGA-AG-4008-01A	63 years, male, stage:iia, alive, 518 days	9815.2
TCGA-AF-A56L-01A	48 years, female, black or african american, stage:iiic, alive, 2007 days	9780.9
TCGA-AG-3591-01A	66 years, female, stage:iia, alive, 1035 days	9772.5
TCGA-AG-A020-01A	57 years, female, stage:iii, alive, 31 days	9641.1
TCGA-AG-A008-01A	50 years, female, stage:i, alive, 424 days	9640.1
TCGA-AF-6136-01A	72 years, female, white, stage:iiib, alive, 741 days	9636.5
TCGA-AF-4110-01A	77 years, male, white, stage:iva, alive, 912 days	9407.8
TCGA-DC-6682-01A	57 years, male, white, stage:iia, alive, 762 days	9365.4
TCGA-AF-3400-01A	54 years, male, white, stage:iia, alive, 1049 days	9363.5
TCGA-F5-6465-01A	64 years, female, white, stage:iia, alive, 1506 days	9348.7
TCGA-EI-6512-01A	64 years, female, white, stage:iiib, alive, 538 days	9262.7
TCGA-AG-3611-01A	72 years, male, stage:iia, alive, 424 days	9255.9
TCGA-AF-A56N-01A	47 years, female, black or african american, stage:iia, alive, 360 days	9254.5
TCGA-EI-6511-01A	52 years, male, white, stage:iiib, alive, 482 days	9199.2
TCGA-AG-3894-01A	65 years, male, stage:iia, alive, 426 days	9003.0
TCGA-CI-6622-01A	74 years, male, white, stage:iib, alive, 1362 days	8993.3
TCGA-AH-6644-01A	73 years, male, white, alive, 838 days	8777.5
TCGA-DC-6157-01A	48 years, male, black or african american, stage:i, alive, 1581 days	8758.8
TCGA-AG-3896-01A	85 years, female, stage:i, alive, 31 days	8681.0
TCGA-AG-3726-01A	63 years, female, stage:i, alive, 243 days	8652.4
TCGA-AG-3885-01A	71 years, female, stage:iiib, alive, 546 days	8649.6
TCGA-EI-6508-01A	48 years, female, white, stage:iiib, alive, 636 days	8641.2
TCGA-DC-6683-01A	43 years, male, white, stage:iiib, alive, 762 days	8632.0
TCGA-F5-6861-01A	60 years, female, white, stage:iia, alive, 1160 days	8608.9
TCGA-AG-A02X-01A	77 years, male, stage:i, alive, 1247 days	8546.8
TCGA-AG-4007-01A	87 years, male, stage:iv, alive, 31 days	8494.5
TCGA-AG-3594-01A	77 years, male, stage:iia, dead, 61 days	8355.5
TCGA-AF-2687-01A	57 years, male, white, stage:iiic, alive, 1427 days	8310.5
TCGA-DT-5265-01A	51 years, male, asian, stage:ii, alive, 384 days	8266.2
TCGA-AF-2690-01A	77 years, female, white, stage:iiic, dead, 524 days	8152.6
TCGA-F5-6464-01A	77 years, female, white, stage:iiic, dead, 303 days	8145.3
TCGA-AF-2693-01A	75 years, male, white, stage:i, alive, 1155 days	8043.4
TCGA-AG-A02G-01A	66 years, male, stage:iv, dead, 1185 days	8006.6
TCGA-DC-6155-01A	31 years, female, white, stage:iiia, alive, 425 days	7957.1
TCGA-AG-3608-01A	79 years, female, stage:iia, alive, 485 days	7922.9
TCGA-F5-6811-01A	72 years, female, white, stage:iia, alive, 979 days	7797.2
TCGA-AG-4005-01A	64 years, male, stage:iv, alive, 427 days	7766.9
TCGA-DC-4749-01A	57 years, male, white, stage:i, alive, 762 days	7558.0
TCGA-AG-3892-01A	57 years, female, stage:i, alive, 396 days	7436.1
TCGA-F5-6864-01A	74 years, female, white, stage:iiib, alive, 379 days	7212.7
TCGA-CL-5917-01A	71 years, female, white, stage:iiic, alive, 2376 days	6984.8
TCGA-EI-6883-01A	63 years, male, white, stage:iic, alive, 350 days	6736.7
TCGA-AG-3887-01A	68 years, male, stage:iia, alive, 1124 days	6729.0
TCGA-AG-3901-01A	67 years, female, stage:iiib, alive, 761 days	6726.2
TCGA-AG-3728-01A	73 years, male, stage:iiib, alive, 912 days	6460.6
TCGA-F5-6702-01A	71 years, male, white, stage:iva, alive, 869 days	6414.5
TCGA-F5-6814-01A	57 years, male, white, stage:iia, alive, 1131 days	6384.7
TCGA-AF-3913-01A	60 years, male, black or african american, stage:iv, dead, 316 days	6335.3
TCGA-AG-3587-01A	65 years, male, stage:i, alive, 1400 days	6287.6
TCGA-AG-3731-01A	65 years, male, stage:iv, alive, 1126 days	6032.2
TCGA-AG-3902-01A	61 years, male, stage:iia, alive, 974 days	5959.6
TCGA-AH-6549-01A	66 years, male, white, alive, 532 days	5824.0
TCGA-AG-3727-01A	78 years, female, stage:iii, alive, 30 days	5715.3
TCGA-AF-6655-01A	66 years, male, white, stage:iiia, alive, 609 days	5684.2
TCGA-AG-4021-01A	84 years, female, stage:iv, dead, 121 days	5490.3
TCGA-DC-6156-01A	62 years, male, white, stage:iva, alive, 943 days	5448.8
TCGA-AG-3598-01A	69 years, male, stage:iia, alive, 1522 days	5437.3
TCGA-AG-3599-01A	70 years, male, stage:i, alive, 366 days	5427.7
TCGA-DC-6158-01A	70 years, male, white, stage:i, dead, 334 days	5160.4
TCGA-DC-6160-01A	68 years, male, white, stage:i, alive, 1339 days	4901.1
TCGA-AG-3881-01A	83 years, female, stage:iia, alive, 579 days	4886.3
TCGA-EI-7002-01A	58 years, male, white, stage:iv, alive, 364 days	4734.0
TCGA-DC-6154-01A	57 years, female, white, stage:iva, alive, 365 days	4683.3
TCGA-F5-6863-01A	71 years, female, white, stage:iiib, dead, 361 days	4472.2
TCGA-AG-3609-01A	65 years, female, stage:iiic, alive, 608 days	4373.2
TCGA-AH-6897-01A	48 years, male, white, stage:i, alive, 804 days	4292.9
TCGA-DC-6681-01A	70 years, female, white, stage:iva, alive, 790 days	4249.6
TCGA-DC-4745-01A	49 years, female, white, stage:iiib, alive, 639 days	3839.9
TCGA-EI-6882-01A	59 years, male, white, stage:iia, alive, 262 days	3579.5
TCGA-EI-6884-01A	71 years, male, white, stage:iiia, alive, 328 days	3531.9
TCGA-EI-6917-01A	33 years, male, white, stage:iiia, alive, 531 days	3343.0
TCGA-EI-6885-01A	57 years, female, white, stage:iv, alive, 415 days	3288.7
TCGA-EI-6507-01A	60 years, male, white, stage:iia, alive, 607 days	3177.1
TCGA-AG-3575-01A	51 years, male, stage:ii, alive, 365 days	2462.9
TCGA-DC-5869-01A	62 years, female, black or african american, stage:iiib, alive, 943 days	2384.4
TCGA-DC-5337-01A	69 years, male, white, stage:i, alive, 792 days	1998.5
TCGA-EI-7004-01A	37 years, female, white, alive, 257 days	1824.6
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