Expression of MT-CYB in pancreatic cancer

PANCREATIC CANCER - Interactive survival scatter plotⁱ

The Survival Scatter plot shows the clinical status (i.e. dead or alive) for all individuals in the patient cohort, based on the same data that underlies the corresponding Kaplan-Meier plots. Patients that are alive at last time for follow-up are shown in blue and patients who have died during the study are shown in red.

The x-axis shows the expression levels (FPKM) of the investigated gene in the tumor tissue at the time of diagnosis. The y-axis shows the follow-up time after diagnosis (years). Both axes are complimented with kernel density curves demonstrating the data density over the axes. The top density plot shows the expression levels (FPKM) distribution among dead (red) and alive patients (blue). The right density plot shows the data density of the survived years of dead patients with high and low expression levels respectively, stratified using the cutoff indicated by the vertical dashed line through the Survival Scatter plot. This cutoff is automatically defined based on the FPKM cutoff that minimizes the p-score. The cutoff can be changed by dragging the vertical line or by entering a cutoff value in the square labeled "Current cut-off".

Under the Survival Scatter plot the p-score landscape (black curve; left axis) is shown together with dead median separation (red curve; right axis). Dead median separation is the difference in median mRNA expression between patients who have died with high and low expression, respectively. It is calculated as follows: median FPKM expression of dead patients with high expression - median FPKM expression of dead patients with low expression. This is intended to aid the user in visually exploring custom cutoffs and the associated p-scores and dead median separation.

Individual patient data is displayed and can be filtered by clicking on one or more of the category buttons on the top of the page. Categories describing expression level and patient information include: high, low, alive, dead, female, male and tumor stages. The scale of the x-axis can be toggled between linear and log-scale by clicking on the "x log" button. Mouse-over function shows TCGA ID, patient information and mRNA expression (FPKM) for each patient.

& Survival analysisⁱ

MT-CYB is not prognostic in pancreatic cancer

Stage:

Survival analysis

Current cut offⁱ:
Best expression cut offⁱ: 4030.92
Median expressionⁱ: N/A
Median follow up timeⁱ: N/A
P scoreⁱ N/A
5-year survival highⁱ N/A
5-year survival lowⁱ N/A

TCGA RNA samplesⁱ

Average FPKM

3898.4

Number of samples

176

Samples

Sample	Description	FPKM
TCGA-RB-A7B8-01A	81 years, female, white, stage:iib, dead, 466 days	9950.0
TCGA-LB-A7SX-01A	74 years, female, black or african american, stage:iib, dead, 393 days	9949.4
TCGA-FB-AAQ1-01A	49 years, male, white, stage:iib, dead, 123 days	9308.7
TCGA-2J-AABK-01A	71 years, male, white, stage:iib, alive, 484 days	9277.7
TCGA-FB-AAQ3-01A	65 years, female, white, stage:iib, dead, 31 days	9139.0
TCGA-HV-A5A5-01A	61 years, female, asian, stage:iib, alive, 289 days	9095.7
TCGA-3A-A9IL-01A	39 years, female, white, stage:i, alive, 2741 days	9004.3
TCGA-2J-AABH-01A	61 years, male, white, stage:iia, alive, 1287 days	8919.6
TCGA-2L-AAQM-01A	52 years, male, white, stage:iib, alive, 1383 days	8477.6
TCGA-FB-AAPY-01A	71 years, male, white, stage:iib, dead, 1059 days	7832.8
TCGA-H8-A6C1-01A	53 years, male, white, stage:iia, alive, 671 days	7768.8
TCGA-3A-A9IV-01A	59 years, female, white, stage:ib, alive, 1103 days	7640.8
TCGA-Q3-AA2A-01A	64 years, female, white, stage:ib, alive, 95 days	7600.3
TCGA-2J-AABT-01A	72 years, female, white, stage:iib, alive, 319 days	7269.2
TCGA-3A-A9IO-01A	56 years, male, white, alive, 1942 days	7227.9
TCGA-IB-A5SP-01A	77 years, male, white, stage:iia, alive, 482 days	6923.5
TCGA-2J-AABE-01A	73 years, male, white, stage:iia, alive, 676 days	6796.1
TCGA-2L-AAQJ-01A	49 years, female, white, stage:iii, dead, 394 days	6762.2
TCGA-US-A779-01A	54 years, female, white, stage:iib, dead, 511 days	6641.3
TCGA-3A-A9I9-01A	67 years, male, white, stage:iia, dead, 634 days	6573.2
TCGA-F2-A8YN-01A	76 years, male, white, stage:iia, alive, 517 days	6549.7
TCGA-M8-A5N4-01A	48 years, female, stage:iia, alive, 584 days	6430.2
TCGA-HZ-A8P1-01A	81 years, male, white, stage:ib, alive, 7 days	6207.8
TCGA-3A-A9IN-01A	62 years, female, white, stage:ib, alive, 2084 days	6168.2
TCGA-Q3-A5QY-01A	58 years, male, white, stage:iib, alive, 416 days	6031.8
TCGA-FB-AAPP-01A	71 years, male, white, stage:iib, dead, 485 days	5957.6
TCGA-3A-A9IS-01A	67 years, male, white, stage:ib, alive, 998 days	5954.3
TCGA-HZ-A77P-01A	77 years, male, white, stage:iib, alive, 330 days	5939.0
TCGA-HV-A5A3-01A	50 years, male, asian, stage:iia, dead, 128 days	5914.5
TCGA-HZ-A4BK-01A	72 years, male, white, stage:iib, alive, 657 days	5883.3
TCGA-FB-AAPQ-01A	65 years, male, white, stage:iib, dead, 1130 days	5567.1
TCGA-2J-AAB1-01A	65 years, male, white, stage:iib, dead, 66 days	5528.3
TCGA-HZ-A9TJ-01A	70 years, male, white, stage:iv, alive, 603 days	5463.1
TCGA-F2-A44H-01A	65 years, male, white, stage:iia, alive, 586 days	5371.5
TCGA-HV-AA8V-01A	50 years, male, asian, stage:iib, alive, 920 days	5248.9
TCGA-HV-A5A6-01A	65 years, female, asian, stage:iib, dead, 2036 days	5170.4
TCGA-3E-AAAY-01A	67 years, male, white, stage:iib, alive, 2285 days	5146.8
TCGA-XN-A8T5-01A	53 years, female, white, stage:ib, alive, 720 days	5145.8
TCGA-3A-A9I7-01A	45 years, male, black or african american, stage:iib, alive, 1323 days	5129.4
TCGA-IB-7649-01A	73 years, female, stage:iib, dead, 467 days	5107.3
TCGA-US-A77G-01A	64 years, male, white, stage:iib, dead, 12 days	5090.8
TCGA-HZ-A49H-01A	68 years, female, white, stage:iib, alive, 491 days	5083.3
TCGA-3E-AAAZ-01A	71 years, male, white, stage:iia, dead, 2182 days	5010.2
TCGA-FB-AAPU-01A	41 years, female, asian, stage:iia, dead, 381 days	4892.9
TCGA-XD-AAUH-01A	57 years, female, white, stage:iib, alive, 395 days	4777.4
TCGA-XD-AAUI-01A	50 years, female, white, stage:iib, dead, 366 days	4704.0
TCGA-S4-A8RM-01A	67 years, male, white, stage:iib, alive, 737 days	4699.9
TCGA-HZ-8519-01A	73 years, male, white, stage:ia, alive, 454 days	4644.1
TCGA-FB-A7DR-01A	48 years, male, asian, stage:iia, dead, 353 days	4599.9
TCGA-2L-AAQL-01A	82 years, male, white, stage:iib, dead, 292 days	4574.7
TCGA-FB-AAQ6-01A	85 years, male, white, stage:ia, dead, 244 days	4570.2
TCGA-3A-A9IX-01A	40 years, male, white, stage:ia, alive, 1037 days	4541.6
TCGA-F2-A44G-01A	79 years, female, white, stage:iib, dead, 233 days	4525.8
TCGA-3A-A9IR-01A	64 years, female, white, stage:ib, alive, 1542 days	4499.3
TCGA-2J-AABA-01A	55 years, male, white, stage:iib, dead, 607 days	4465.3
TCGA-HV-A5A4-01A	72 years, female, asian, stage:iia, alive, 232 days	4460.4
TCGA-FB-AAPZ-01A	54 years, male, white, stage:iib, alive, 716 days	4417.6
TCGA-US-A77E-01A	73 years, male, white, stage:iib, dead, 430 days	4339.5
TCGA-2L-AAQE-01A	56 years, male, white, stage:iib, dead, 684 days	4297.8
TCGA-RL-AAAS-01A	60 years, female, white, stage:ib, alive, 9 days	4286.8
TCGA-2J-AABF-01A	73 years, male, white, stage:iib, dead, 691 days	4282.9
TCGA-IB-A5SO-01A	71 years, male, white, stage:iib, dead, 365 days	4262.9
TCGA-IB-AAUR-01A	67 years, male, white, stage:iib, alive, 338 days	4228.8
TCGA-YH-A8SY-01A	73 years, female, white, alive, 388 days	4219.8
TCGA-US-A776-01A	61 years, male, white, stage:iia, alive, 1216 days	4213.7
TCGA-HZ-8315-01A	54 years, female, white, stage:iia, dead, 299 days	4180.1
TCGA-S4-A8RP-01A	77 years, female, white, stage:iib, dead, 702 days	4172.7
TCGA-3A-A9IH-01A	66 years, female, white, stage:ia, alive, 1021 days	4123.9
TCGA-F2-6880-01A	70 years, male, white, stage:iib, alive, 289 days	4099.1
TCGA-XN-A8T3-01A	67 years, male, white, stage:ib, alive, 951 days	4058.5
TCGA-2J-AABR-01A	60 years, female, white, stage:iia, alive, 438 days	4033.7
TCGA-HZ-7289-01A	77 years, male, white, stage:iib, dead, 661 days	4028.1
TCGA-IB-AAUO-01A	64 years, female, white, stage:iib, dead, 239 days	4011.4
TCGA-HZ-8317-01A	69 years, female, white, stage:iib, dead, 378 days	4004.4
TCGA-HV-A7OP-01A	72 years, male, asian, stage:iib, alive, 978 days	3937.4
TCGA-FB-AAQ2-01A	81 years, female, white, stage:iib, dead, 153 days	3932.1
TCGA-IB-A6UG-01A	65 years, male, white, stage:iib, dead, 41 days	3909.2
TCGA-2L-AAQI-01A	66 years, male, white, stage:iib, dead, 103 days	3862.5
TCGA-HZ-8637-01A	76 years, female, white, stage:iib, dead, 517 days	3852.4
TCGA-H6-A45N-01A	88 years, female, white, stage:iib, dead, 421 days	3843.5
TCGA-FB-A78T-01A	71 years, female, white, stage:iib, dead, 375 days	3812.6
TCGA-XD-AAUG-01A	66 years, female, white, stage:iv, alive, 420 days	3798.4
TCGA-FB-AAPS-01A	62 years, female, white, stage:iib, alive, 228 days	3793.5
TCGA-IB-AAUM-01A	76 years, male, white, stage:iib, alive, 8 days	3780.7
TCGA-IB-AAUW-01A	63 years, female, white, stage:iib, dead, 230 days	3779.8
TCGA-HZ-A49I-01A	77 years, male, white, stage:iib, dead, 308 days	3767.0
TCGA-PZ-A5RE-01A	44 years, female, white, stage:iib, dead, 470 days	3766.4
TCGA-IB-AAUQ-01A	50 years, male, white, stage:iib, dead, 183 days	3762.7
TCGA-HZ-8638-01A	84 years, female, white, stage:ia, dead, 151 days	3716.5
TCGA-HZ-A49G-01A	58 years, female, white, stage:iib, alive, 660 days	3692.5
TCGA-IB-A6UF-01A	63 years, male, white, stage:iib, alive, 666 days	3637.8
TCGA-2J-AABO-01A	43 years, male, white, stage:iib, alive, 440 days	3602.9
TCGA-FB-A4P5-01A	69 years, female, white, stage:iib, dead, 179 days	3541.8
TCGA-2J-AAB8-01A	71 years, male, white, stage:iib, alive, 80 days	3465.4
TCGA-2J-AABU-01A	56 years, male, white, stage:iib, dead, 277 days	3400.5
TCGA-IB-AAUT-01A	65 years, male, white, stage:iib, alive, 287 days	3366.0
TCGA-FB-A4P6-01A	54 years, male, white, stage:iib, alive, 767 days	3318.3
TCGA-2J-AAB4-01A	48 years, male, white, stage:iib, alive, 729 days	3301.3
TCGA-US-A77J-01A	81 years, female, white, stage:iib, dead, 568 days	3286.9
TCGA-IB-AAUP-01A	68 years, male, white, stage:iib, alive, 431 days	3260.3
TCGA-IB-AAUV-01A	49 years, male, white, stage:iib, alive, 404 days	3198.2
TCGA-US-A774-01A	76 years, female, white, stage:iib, dead, 695 days	3177.6
TCGA-OE-A75W-01A	75 years, male, white, stage:iia, dead, 267 days	3141.0
TCGA-FB-A545-01A	72 years, female, white, stage:iib, dead, 732 days	3123.0
TCGA-FB-AAQ0-01A	68 years, male, white, stage:iia, dead, 473 days	3121.8
TCGA-IB-A5ST-01A	64 years, female, white, stage:iib, alive, 635 days	3074.3
TCGA-3A-A9J0-01A	75 years, male, white, stage:iib, alive, 743 days	3045.0
TCGA-RB-AA9M-01A	43 years, male, white, stage:iib, alive, 286 days	3024.2
TCGA-2J-AAB9-01A	71 years, female, white, stage:iib, dead, 627 days	3011.6
TCGA-IB-8126-01A	80 years, female, white, stage:iii, alive, 462 days	2986.7
TCGA-3A-A9I5-01A	58 years, male, white, alive, 1794 days	2968.6
TCGA-IB-A7LX-01A	57 years, male, white, stage:iib, dead, 250 days	2926.9
TCGA-L1-A7W4-01A	48 years, female, white, stage:iib, dead, 278 days	2925.5
TCGA-F2-A7TX-01A	77 years, male, white, stage:iib, dead, 95 days	2895.2
TCGA-HV-AA8X-01A	75 years, female, asian, stage:iib, dead, 532 days	2883.7
TCGA-Z5-AAPL-01A	74 years, female, white, stage:iia, alive, 467 days	2856.6
TCGA-HZ-A4BH-01A	75 years, male, white, stage:iib, alive, 194 days	2854.8
TCGA-HZ-A77Q-01A	55 years, female, white, stage:iib, alive, 33 days	2834.2
TCGA-IB-AAUU-01A	35 years, male, white, stage:iib, alive, 245 days	2826.1
TCGA-2J-AABI-01A	55 years, female, white, stage:iia, alive, 969 days	2817.6
TCGA-IB-7652-01A	49 years, female, asian, stage:iib, alive, 1116 days	2791.6
TCGA-YB-A89D-01A	59 years, male, white, stage:iib, alive, 350 days	2741.3
TCGA-IB-AAUN-01A	74 years, female, white, stage:ib, dead, 144 days	2719.8
TCGA-HZ-7923-01A	65 years, male, white, stage:iia, alive, 314 days	2679.1
TCGA-IB-A5SQ-01A	56 years, female, white, stage:ib, dead, 219 days	2655.9
TCGA-HZ-7924-01A	60 years, female, white, stage:iia, alive, 840 days	2653.4
TCGA-3A-A9IJ-01A	65 years, male, white, stage:ib, alive, 1854 days	2516.3
TCGA-XD-AAUL-01A	56 years, male, white, stage:iia, alive, 498 days	2477.3
TCGA-3A-A9IC-01A	61 years, female, white, stage:iib, dead, 738 days	2401.6
TCGA-IB-7889-01A	86 years, female, white, stage:iib, dead, 481 days	2362.5
TCGA-IB-A7M4-01A	81 years, male, white, stage:iib, alive, 483 days	2342.3
TCGA-3A-A9IU-01A	65 years, male, white, stage:iib, dead, 458 days	2336.8
TCGA-3A-A9IB-01A	69 years, female, white, stage:iib, dead, 224 days	2334.2
TCGA-IB-7644-01A	65 years, female, white, stage:iv, dead, 394 days	2329.8
TCGA-LB-A9Q5-01A	63 years, female, white, stage:iib, dead, 313 days	2301.1
TCGA-HZ-7926-01A	57 years, male, black or african american, stage:iib, dead, 518 days	2274.8
TCGA-IB-AAUS-01A	84 years, female, white, stage:iib, alive, 225 days	2271.7
TCGA-IB-7897-01A	54 years, female, white, stage:iib, dead, 486 days	2260.5
TCGA-2L-AAQA-01A	76 years, male, white, stage:iib, dead, 143 days	2191.7
TCGA-YY-A8LH-01A	61 years, female, white, stage:iib, alive, 2016 days	2174.5
TCGA-HZ-8002-01A	61 years, male, white, stage:iib, dead, 366 days	2173.1
TCGA-IB-7887-01A	62 years, female, white, stage:iib, dead, 110 days	2173.1
TCGA-F2-7276-01A	64 years, male, white, stage:iib, dead, 216 days	2133.2
TCGA-FB-A5VM-01A	74 years, male, white, stage:ib, dead, 498 days	2114.1
TCGA-IB-7645-01A	44 years, female, stage:iib, dead, 1502 days	2089.1
TCGA-HZ-8636-01A	58 years, female, white, stage:iv, dead, 545 days	2066.3
TCGA-S4-A8RO-01A	75 years, female, white, stage:iib, alive, 525 days	2032.5
TCGA-HZ-A77O-01A	77 years, female, white, stage:iib, dead, 160 days	1982.0
TCGA-H6-8124-01A	56 years, female, white, stage:iib, alive, 392 days	1962.9
TCGA-LB-A8F3-01A	64 years, female, black or african american, stage:iia, alive, 379 days	1922.2
TCGA-IB-7651-01A	64 years, female, white, stage:iib, dead, 603 days	1867.7
TCGA-IB-7885-01A	78 years, female, white, stage:iib, alive, 1257 days	1854.1
TCGA-2J-AAB6-01A	75 years, male, white, stage:iia, dead, 293 days	1753.0
TCGA-IB-7654-01A	80 years, male, white, stage:iib, dead, 476 days	1752.2
TCGA-HZ-7925-01A	66 years, male, white, stage:iib, dead, 614 days	1702.3
TCGA-HZ-8001-01A	69 years, male, white, stage:iii, alive, 706 days	1644.4
TCGA-2J-AABV-01A	74 years, male, white, stage:iib, dead, 652 days	1634.7
TCGA-IB-7646-01A	60 years, male, white, stage:iib, dead, 145 days	1539.2
TCGA-2J-AABP-01A	58 years, female, white, stage:iib, alive, 463 days	1488.6
TCGA-IB-8127-01A	59 years, male, white, stage:iib, alive, 522 days	1454.6
TCGA-IB-7890-01A	73 years, male, stage:ib, dead, 598 days	1450.0
TCGA-HZ-7920-01A	71 years, male, white, stage:ib, dead, 236 days	1441.6
TCGA-HZ-7919-01A	52 years, female, white, stage:iib, dead, 593 days	1418.5
TCGA-HZ-8003-01A	65 years, female, white, stage:iib, dead, 596 days	1404.0
TCGA-IB-7888-01A	66 years, female, black or african american, stage:iia, dead, 1332 days	1334.2
TCGA-3A-A9IZ-01A	47 years, male, white, stage:iib, dead, 308 days	1300.3
TCGA-F2-7273-01A	54 years, male, black or african american, stage:iib, dead, 592 days	1273.7
TCGA-IB-7891-01A	49 years, female, white, stage:iib, dead, 913 days	1263.4
TCGA-IB-A5SS-01A	64 years, female, white, stage:iib, dead, 460 days	1231.2
TCGA-F2-6879-01A	57 years, male, white, stage:iib, dead, 334 days	1116.2
TCGA-HZ-7918-01A	72 years, male, white, stage:iib, alive, 969 days	1006.7
TCGA-HZ-7922-01A	61 years, female, white, stage:iib, alive, 4 days	935.4
TCGA-HV-A7OL-01A	70 years, male, asian, stage:iia, alive, 252 days	909.1
TCGA-IB-7886-01A	80 years, male, white, stage:iib, dead, 123 days	903.4
TCGA-IB-7893-01A	64 years, male, white, stage:iia, dead, 117 days	899.0
TCGA-HZ-8005-01A	81 years, male, white, stage:iib, dead, 120 days	723.2
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PANCREATIC CANCER - Protein expressionⁱ A mouse-over function shows sample information and annotation data. Click on an image to view it in a full screen mode. Samples can be filtered based on level of antibody staining by selecting one or several of the following categories: high, medium, low and not detected. The assay and annotation is described here. Note that samples used for immunohistochemistry by the Human Protein Atlas do not correspond to samples in the TCGA dataset.

Antibody stainingⁱ Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high. This score is based on the staining intensity and fraction of stained cells. Read more	Antibody HPA068400	Antibody CAB032215
Staining
High
Medium
Low
Not detected
Intensity
Strong
Moderate
Weak
Negative
Quantity
>75%
75%-25%
<25%
None
Location
Nuclear
Cytoplasmic/membranous
Cytoplasmic/membranous,nuclear
None
Click images for details