Expression of MT-ND2 in colorectal cancer

RECTUM ADENOCARCINOMA (READ) - Interactive survival scatter plotⁱ

The Survival Scatter plot shows the clinical status (i.e. dead or alive) for all individuals in the patient cohort, based on the same data that underlies the corresponding Kaplan-Meier plots. Patients that are alive at last time for follow-up are shown in blue and patients who have died during the study are shown in red.

The x-axis shows the expression levels (FPKM) of the investigated gene in the tumor tissue at the time of diagnosis. The y-axis shows the follow-up time after diagnosis (years). Both axes are complimented with kernel density curves demonstrating the data density over the axes. The top density plot shows the expression levels (FPKM) distribution among dead (red) and alive patients (blue). The right density plot shows the data density of the survived years of dead patients with high and low expression levels respectively, stratified using the cutoff indicated by the vertical dashed line through the Survival Scatter plot. This cutoff is automatically defined based on the FPKM cutoff that minimizes the p-score. The cutoff can be changed by dragging the vertical line or by entering a cutoff value in the square labeled "Current cut-off".

Under the Survival Scatter plot the p-score landscape (black curve; left axis) is shown together with dead median separation (red curve; right axis). Dead median separation is the difference in median mRNA expression between patients who have died with high and low expression, respectively. It is calculated as follows: median FPKM expression of dead patients with high expression - median FPKM expression of dead patients with low expression. This is intended to aid the user in visually exploring custom cutoffs and the associated p-scores and dead median separation.

Individual patient data is displayed and can be filtered by clicking on one or more of the category buttons on the top of the page. Categories describing expression level and patient information include: high, low, alive, dead, female, male and tumor stages. The scale of the x-axis can be toggled between linear and log-scale by clicking on the "x log" button. Mouse-over function shows TCGA ID, patient information and mRNA expression (FPKM) for each patient.

& Survival analysisⁱ

Stage:

Survival analysis

Current cut offⁱ:
Best expression cut offⁱ: 4192.57
Median expressionⁱ: N/A
Median follow up timeⁱ: N/A
P scoreⁱ N/A
5-year survival highⁱ N/A
5-year survival lowⁱ N/A

TCGA RNA samplesⁱ

Average FPKM

4309.9

Number of samples

159

Samples

Sample	Description	FPKM
TCGA-DY-A1DF-01A	73 years, female, white, stage:iiic, dead, 734 days	22346.7
TCGA-DY-A1DD-01A	77 years, female, white, stage:iiib, dead, 1741 days	22031.6
TCGA-BM-6198-01A	73 years, male, white, stage:iiib, alive, 646 days	14448.0
TCGA-EI-6514-01A	59 years, female, white, stage:iia, alive, 496 days	13578.9
TCGA-DY-A1H8-01A	77 years, female, white, stage:iiia, dead, 992 days	13036.3
TCGA-AF-A56K-01A	56 years, male, black or african american, stage:iia, alive, 2635 days	11755.9
TCGA-CL-5918-01A	90 years, female, white, stage:iia, alive, 218 days	11666.1
TCGA-DY-A1DG-01A	75 years, male, white, stage:iva, dead, 1566 days	11179.3
TCGA-AG-A011-01A	80 years, male, stage:iia, alive, 1126 days	11158.5
TCGA-DY-A1DC-01A	72 years, female, white, stage:iia, dead, 1258 days	10915.8
TCGA-G5-6572-01A	56 years, male, white, dead, 1432 days	10648.2
TCGA-F5-6812-01A	67 years, male, white, stage:iia, alive, 1110 days	9995.9
TCGA-AG-A026-01A	66 years, male, stage:ii, dead, 59 days	9390.7
TCGA-G5-6235-01A	72 years, male, white, stage:iiib, alive, 1696 days	8681.9
TCGA-AG-3732-01A	78 years, female, stage:i, alive, 1003 days	8630.1
TCGA-AF-5654-01A	73 years, female, white, stage:i, dead, 512 days	8140.1
TCGA-AG-A032-01A	68 years, male, stage:iiib, alive, 1157 days	7399.3
TCGA-AG-3742-01A	85 years, female, stage:i, alive, 30 days	6882.3
TCGA-F5-6813-01A	70 years, male, white, stage:iiic, dead, 598 days	6797.0
TCGA-AH-6547-01A	79 years, female, white, dead, 76 days	6733.0
TCGA-AG-A01J-01A	59 years, female, stage:iia, alive, 31 days	6573.7
TCGA-EI-6506-01A	78 years, female, white, stage:iia, alive, 625 days	6569.5
TCGA-AG-A02N-01A	67 years, male, stage:ii, alive, 1885 days	6489.5
TCGA-AF-6672-01A	43 years, male, white, stage:iv, alive, 748 days	6428.1
TCGA-CI-6624-01C	53 years, female, white, stage:i, alive, 1466 days	6329.9
TCGA-EF-5830-01A	54 years, male, white, stage:iib, alive, 106 days	6312.7
TCGA-AF-2691-01A	48 years, female, white, stage:i, alive, 1309 days	6052.0
TCGA-EI-6510-01A	77 years, female, white, alive, 556 days	6006.3
TCGA-EI-6509-01A	53 years, male, white, stage:iiic, alive, 517 days	5972.9
TCGA-AG-3593-01A	72 years, female, stage:iia, alive, 1035 days	5954.2
TCGA-DC-6682-01A	57 years, male, white, stage:iia, alive, 762 days	5911.2
TCGA-DY-A0XA-01A	57 years, female, white, stage:iia, alive, 3846 days	5826.5
TCGA-EI-6513-01A	59 years, male, white, stage:iiib, alive, 497 days	5643.0
TCGA-AG-A00C-01A	49 years, female, stage:iiib, alive, 183 days	5639.9
TCGA-CI-6622-01A	74 years, male, white, stage:iib, alive, 1362 days	5627.4
TCGA-F5-6571-01A	62 years, female, white, stage:iia, alive, 1288 days	5578.2
TCGA-CL-4957-01A	79 years, female, dead, 425 days	5378.4
TCGA-CI-6619-01B	41 years, male, white, stage:iv, alive, 184 days	5378.0
TCGA-DT-5265-01A	51 years, male, asian, stage:ii, alive, 384 days	5371.2
TCGA-DY-A1DE-01A	56 years, female, white, stage:iia, alive, 3932 days	5271.8
TCGA-AH-6544-01A	60 years, male, white, alive, 1173 days	5194.4
TCGA-CI-6621-01A	63 years, male, white, stage:iiib, alive, 419 days	5135.1
TCGA-G5-6641-01A	67 years, male, white, stage:iiia, alive, 804 days	5009.1
TCGA-AG-3890-01A	62 years, male, stage:i, alive, 518 days	4707.6
TCGA-F5-6465-01A	64 years, female, white, stage:iia, alive, 1506 days	4705.9
TCGA-EI-6511-01A	52 years, male, white, stage:iiib, alive, 482 days	4698.5
TCGA-AG-A00Y-01A	68 years, male, stage:iia, alive, 700 days	4695.1
TCGA-G5-6233-01A	74 years, male, white, dead, 556 days	4644.6
TCGA-AG-A00H-01A	75 years, male, stage:iia, alive, 790 days	4625.7
TCGA-AG-3893-01A	74 years, male, stage:iiib, alive, 1065 days	4618.0
TCGA-AG-3882-01A	66 years, female, stage:i, alive, 608 days	4592.1
TCGA-AG-A01N-01A	68 years, female, stage:iv, alive, 943 days	4558.6
TCGA-AG-3898-01A	61 years, male, stage:iia, alive, 1461 days	4521.6
TCGA-CI-6620-01A	41 years, female, white, stage:iva, alive, 1009 days	4502.8
TCGA-AH-6643-01A	50 years, male, white, stage:iiic, dead, 1314 days	4470.2
TCGA-F5-6702-01A	71 years, male, white, stage:iva, alive, 869 days	4379.8
TCGA-AF-2690-01A	77 years, female, white, stage:iiic, dead, 524 days	4299.2
TCGA-AG-A02G-01A	66 years, male, stage:iv, dead, 1185 days	4205.4
TCGA-AG-3584-01A	60 years, male, stage:iv, dead, 730 days	4198.0
TCGA-EI-6881-01A	60 years, male, white, stage:iiia, alive, 499 days	4187.1
TCGA-AG-A002-01A	35 years, male, stage:i, alive, 638 days	4174.8
TCGA-CI-6623-01B	44 years, male, white, stage:i, alive, 1443 days	4170.2
TCGA-AG-3725-01A	90 years, female, stage:iii, alive, 638 days	4145.1
TCGA-AF-A56L-01A	48 years, female, black or african american, stage:iiic, alive, 2007 days	4130.2
TCGA-AG-4021-01A	84 years, female, stage:iv, dead, 121 days	4114.7
TCGA-AG-4022-01A	59 years, female, stage:ii, alive, 1400 days	4098.2
TCGA-AF-3911-01A	48 years, male, white, stage:iiic, alive, 1148 days	4066.3
TCGA-AG-3600-01A	62 years, male, stage:iiic, alive, 184 days	4034.5
TCGA-AG-A015-01A	64 years, female, stage:i, alive, 1096 days	4003.4
TCGA-F5-6814-01A	57 years, male, white, stage:iia, alive, 1131 days	4000.8
TCGA-AG-4008-01A	63 years, male, stage:iia, alive, 518 days	3954.6
TCGA-AG-A025-01A	62 years, female, stage:i, alive, 1520 days	3904.1
TCGA-AG-3592-01A	68 years, male, stage:iia, alive, 1035 days	3878.1
TCGA-F5-6811-01A	72 years, female, white, stage:iia, alive, 979 days	3871.8
TCGA-CL-5917-01A	71 years, female, white, stage:iiic, alive, 2376 days	3862.6
TCGA-AF-6136-01A	72 years, female, white, stage:iiib, alive, 741 days	3846.9
TCGA-AG-3578-01A	76 years, female, stage:iia, alive, 974 days	3831.8
TCGA-AF-A56N-01A	47 years, female, black or african american, stage:iia, alive, 360 days	3715.5
TCGA-DC-6157-01A	48 years, male, black or african american, stage:i, alive, 1581 days	3642.3
TCGA-AG-3574-01A	89 years, female, stage:ii, dead, 1096 days	3635.5
TCGA-AG-A036-01A	71 years, male, stage:iii, alive, 3562 days	3625.7
TCGA-AG-A014-01A	86 years, male, stage:i, alive, 485 days	3456.8
TCGA-AF-2687-01A	57 years, male, white, stage:iiic, alive, 1427 days	3432.1
TCGA-AF-2693-01A	75 years, male, white, stage:i, alive, 1155 days	3393.7
TCGA-AF-2692-01A	54 years, female, white, stage:iia, alive, 412 days	3388.5
TCGA-AG-3594-01A	77 years, male, stage:iia, dead, 61 days	3354.5
TCGA-EF-5831-01A	72 years, male, white, stage:iia, alive, 127 days	3270.8
TCGA-AG-A023-01A	62 years, female, stage:iv, dead, 1581 days	3250.3
TCGA-AH-6644-01A	73 years, male, white, alive, 838 days	3238.3
TCGA-AG-3608-01A	79 years, female, stage:iia, alive, 485 days	3202.4
TCGA-AG-3731-01A	65 years, male, stage:iv, alive, 1126 days	3193.4
TCGA-AF-6655-01A	66 years, male, white, stage:iiia, alive, 609 days	3069.2
TCGA-AG-A020-01A	57 years, female, stage:iii, alive, 31 days	3059.2
TCGA-AH-6549-01A	66 years, male, white, alive, 532 days	2995.4
TCGA-AF-4110-01A	77 years, male, white, stage:iva, alive, 912 days	2968.2
TCGA-DC-6160-01A	68 years, male, white, stage:i, alive, 1339 days	2956.3
TCGA-AG-3909-01A	69 years, female, stage:iiib, alive, 608 days	2931.9
TCGA-AG-4005-01A	64 years, male, stage:iv, alive, 427 days	2928.9
TCGA-EI-6508-01A	48 years, female, white, stage:iiib, alive, 636 days	2896.9
TCGA-AG-A02X-01A	77 years, male, stage:i, alive, 1247 days	2838.0
TCGA-EI-6883-01A	63 years, male, white, stage:iic, alive, 350 days	2819.0
TCGA-AG-3901-01A	67 years, female, stage:iiib, alive, 761 days	2800.9
TCGA-AG-4001-01A	74 years, female, stage:iia, alive, 1096 days	2798.5
TCGA-AG-3581-01A	63 years, male, stage:i, alive, 215 days	2689.0
TCGA-AG-4007-01A	87 years, male, stage:iv, alive, 31 days	2673.8
TCGA-AG-3591-01A	66 years, female, stage:iia, alive, 1035 days	2659.7
TCGA-AG-3580-01A	67 years, male, stage:i, alive, 244 days	2641.8
TCGA-F5-6464-01A	77 years, female, white, stage:iiic, dead, 303 days	2622.3
TCGA-AG-3902-01A	61 years, male, stage:iia, alive, 974 days	2604.7
TCGA-AH-6903-01A	46 years, male, white, stage:iiib, alive, 592 days	2558.0
TCGA-AG-3583-01A	66 years, male, stage:iv, dead, 610 days	2531.4
TCGA-F5-6863-01A	71 years, female, white, stage:iiib, dead, 361 days	2466.9
TCGA-AG-3611-01A	72 years, male, stage:iia, alive, 424 days	2456.4
TCGA-AG-3605-01A	85 years, female, stage:iv, alive, 30 days	2428.8
TCGA-DC-4749-01A	57 years, male, white, stage:i, alive, 762 days	2400.8
TCGA-AG-3612-01A	55 years, female, stage:iiib, alive, 608 days	2371.8
TCGA-AG-A008-01A	50 years, female, stage:i, alive, 424 days	2329.5
TCGA-EI-7002-01A	58 years, male, white, stage:iv, alive, 364 days	2311.7
TCGA-AG-3582-01A	75 years, male, stage:iv, dead, 1096 days	2309.3
TCGA-EI-6512-01A	64 years, female, white, stage:iiib, alive, 538 days	2301.3
TCGA-AG-3999-01A	61 years, female, stage:iiic, alive, 853 days	2291.7
TCGA-DC-6681-01A	70 years, female, white, stage:iva, alive, 790 days	2281.3
TCGA-DC-6683-01A	43 years, male, white, stage:iiib, alive, 762 days	2206.0
TCGA-AG-3586-01A	72 years, female, stage:iii, alive, 31 days	2075.7
TCGA-AG-A016-01A	55 years, male, stage:iv, alive, 276 days	2006.1
TCGA-AG-3587-01A	65 years, male, stage:i, alive, 1400 days	2000.5
TCGA-AG-3878-01A	64 years, male, stage:i, alive, 30 days	1997.7
TCGA-AG-3896-01A	85 years, female, stage:i, alive, 31 days	1985.9
TCGA-AG-3894-01A	65 years, male, stage:iia, alive, 426 days	1926.3
TCGA-F5-6864-01A	74 years, female, white, stage:iiib, alive, 379 days	1850.3
TCGA-EI-6507-01A	60 years, male, white, stage:iia, alive, 607 days	1801.3
TCGA-AG-3726-01A	63 years, female, stage:i, alive, 243 days	1735.9
TCGA-DC-6156-01A	62 years, male, white, stage:iva, alive, 943 days	1666.7
TCGA-AG-3598-01A	69 years, male, stage:iia, alive, 1522 days	1660.6
TCGA-AF-3913-01A	60 years, male, black or african american, stage:iv, dead, 316 days	1525.6
TCGA-AH-6897-01A	48 years, male, white, stage:i, alive, 804 days	1506.0
TCGA-AG-3887-01A	68 years, male, stage:iia, alive, 1124 days	1469.7
TCGA-AG-3599-01A	70 years, male, stage:i, alive, 366 days	1425.2
TCGA-AG-3883-01A	69 years, male, stage:i, alive, 31 days	1411.8
TCGA-DC-6158-01A	70 years, male, white, stage:i, dead, 334 days	1411.4
TCGA-AG-3728-01A	73 years, male, stage:iiib, alive, 912 days	1397.3
TCGA-EI-6885-01A	57 years, female, white, stage:iv, alive, 415 days	1396.4
TCGA-AF-3400-01A	54 years, male, white, stage:iia, alive, 1049 days	1388.8
TCGA-EI-6884-01A	71 years, male, white, stage:iiia, alive, 328 days	1386.7
TCGA-F5-6861-01A	60 years, female, white, stage:iia, alive, 1160 days	1348.2
TCGA-EI-6917-01A	33 years, male, white, stage:iiia, alive, 531 days	1339.6
TCGA-DC-4745-01A	49 years, female, white, stage:iiib, alive, 639 days	1302.8
TCGA-AG-3881-01A	83 years, female, stage:iia, alive, 579 days	1263.1
TCGA-EI-6882-01A	59 years, male, white, stage:iia, alive, 262 days	1200.4
TCGA-AG-3892-01A	57 years, female, stage:i, alive, 396 days	1117.4
TCGA-AG-3609-01A	65 years, female, stage:iiic, alive, 608 days	1088.6
TCGA-AG-3885-01A	71 years, female, stage:iiib, alive, 546 days	1039.1
TCGA-DC-5869-01A	62 years, female, black or african american, stage:iiib, alive, 943 days	858.6
TCGA-AG-3575-01A	51 years, male, stage:ii, alive, 365 days	730.5
TCGA-DC-6154-01A	57 years, female, white, stage:iva, alive, 365 days	729.6
TCGA-AG-3727-01A	78 years, female, stage:iii, alive, 30 days	722.5
TCGA-DC-5337-01A	69 years, male, white, stage:i, alive, 792 days	643.0
TCGA-DC-6155-01A	31 years, female, white, stage:iiia, alive, 425 days	634.7
TCGA-EI-7004-01A	37 years, female, white, alive, 257 days	465.4
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