Expression of MT-ND3 in colorectal cancer

RECTUM ADENOCARCINOMA (READ) - Interactive survival scatter plotⁱ

The Survival Scatter plot shows the clinical status (i.e. dead or alive) for all individuals in the patient cohort, based on the same data that underlies the corresponding Kaplan-Meier plots. Patients that are alive at last time for follow-up are shown in blue and patients who have died during the study are shown in red.

The x-axis shows the expression levels (FPKM) of the investigated gene in the tumor tissue at the time of diagnosis. The y-axis shows the follow-up time after diagnosis (years). Both axes are complimented with kernel density curves demonstrating the data density over the axes. The top density plot shows the expression levels (FPKM) distribution among dead (red) and alive patients (blue). The right density plot shows the data density of the survived years of dead patients with high and low expression levels respectively, stratified using the cutoff indicated by the vertical dashed line through the Survival Scatter plot. This cutoff is automatically defined based on the FPKM cutoff that minimizes the p-score. The cutoff can be changed by dragging the vertical line or by entering a cutoff value in the square labeled "Current cut-off".

Under the Survival Scatter plot the p-score landscape (black curve; left axis) is shown together with dead median separation (red curve; right axis). Dead median separation is the difference in median mRNA expression between patients who have died with high and low expression, respectively. It is calculated as follows: median FPKM expression of dead patients with high expression - median FPKM expression of dead patients with low expression. This is intended to aid the user in visually exploring custom cutoffs and the associated p-scores and dead median separation.

Individual patient data is displayed and can be filtered by clicking on one or more of the category buttons on the top of the page. Categories describing expression level and patient information include: high, low, alive, dead, female, male and tumor stages. The scale of the x-axis can be toggled between linear and log-scale by clicking on the "x log" button. Mouse-over function shows TCGA ID, patient information and mRNA expression (FPKM) for each patient.

& Survival analysisⁱ

Stage:

Survival analysis

Current cut offⁱ:
Best expression cut offⁱ: 5307.73
Median expressionⁱ: N/A
Median follow up timeⁱ: N/A
P scoreⁱ N/A
5-year survival highⁱ N/A
5-year survival lowⁱ N/A

TCGA RNA samplesⁱ

Average FPKM

5216.7

Number of samples

159

Samples

Sample	Description	FPKM
TCGA-DY-A1DF-01A	73 years, female, white, stage:iiic, dead, 734 days	44155.9
TCGA-CL-5918-01A	90 years, female, white, stage:iia, alive, 218 days	24126.8
TCGA-EI-6514-01A	59 years, female, white, stage:iia, alive, 496 days	23464.1
TCGA-DY-A1DG-01A	75 years, male, white, stage:iva, dead, 1566 days	18142.3
TCGA-F5-6812-01A	67 years, male, white, stage:iia, alive, 1110 days	15778.5
TCGA-DY-A1H8-01A	77 years, female, white, stage:iiia, dead, 992 days	14501.4
TCGA-BM-6198-01A	73 years, male, white, stage:iiib, alive, 646 days	13810.0
TCGA-AF-A56K-01A	56 years, male, black or african american, stage:iia, alive, 2635 days	13219.5
TCGA-DY-A1DD-01A	77 years, female, white, stage:iiib, dead, 1741 days	13141.8
TCGA-G5-6572-01A	56 years, male, white, dead, 1432 days	11991.8
TCGA-AG-3732-01A	78 years, female, stage:i, alive, 1003 days	11910.8
TCGA-AG-A011-01A	80 years, male, stage:iia, alive, 1126 days	11321.2
TCGA-AG-A032-01A	68 years, male, stage:iiib, alive, 1157 days	10748.1
TCGA-DY-A1DC-01A	72 years, female, white, stage:iia, dead, 1258 days	10337.0
TCGA-F5-6813-01A	70 years, male, white, stage:iiic, dead, 598 days	10310.8
TCGA-AG-3742-01A	85 years, female, stage:i, alive, 30 days	10251.6
TCGA-AG-A026-01A	66 years, male, stage:ii, dead, 59 days	10154.9
TCGA-AH-6544-01A	60 years, male, white, alive, 1173 days	10149.9
TCGA-EI-6509-01A	53 years, male, white, stage:iiic, alive, 517 days	9934.0
TCGA-DC-6682-01A	57 years, male, white, stage:iia, alive, 762 days	9319.1
TCGA-G5-6235-01A	72 years, male, white, stage:iiib, alive, 1696 days	8822.4
TCGA-G5-6641-01A	67 years, male, white, stage:iiia, alive, 804 days	8637.8
TCGA-AG-3898-01A	61 years, male, stage:iia, alive, 1461 days	8104.0
TCGA-AG-A015-01A	64 years, female, stage:i, alive, 1096 days	7675.3
TCGA-AG-A01J-01A	59 years, female, stage:iia, alive, 31 days	7644.1
TCGA-AF-6672-01A	43 years, male, white, stage:iv, alive, 748 days	7354.5
TCGA-CI-6624-01C	53 years, female, white, stage:i, alive, 1466 days	7126.9
TCGA-AG-A00H-01A	75 years, male, stage:iia, alive, 790 days	7059.9
TCGA-CI-6621-01A	63 years, male, white, stage:iiib, alive, 419 days	6367.6
TCGA-AG-A02G-01A	66 years, male, stage:iv, dead, 1185 days	6183.2
TCGA-AF-5654-01A	73 years, female, white, stage:i, dead, 512 days	6175.7
TCGA-CL-5917-01A	71 years, female, white, stage:iiic, alive, 2376 days	6058.2
TCGA-AG-A002-01A	35 years, male, stage:i, alive, 638 days	5904.5
TCGA-AG-3890-01A	62 years, male, stage:i, alive, 518 days	5856.2
TCGA-AG-A00Y-01A	68 years, male, stage:iia, alive, 700 days	5800.6
TCGA-EF-5830-01A	54 years, male, white, stage:iib, alive, 106 days	5783.0
TCGA-F5-6465-01A	64 years, female, white, stage:iia, alive, 1506 days	5752.0
TCGA-AG-3600-01A	62 years, male, stage:iiic, alive, 184 days	5740.5
TCGA-EI-6510-01A	77 years, female, white, alive, 556 days	5724.5
TCGA-AG-3725-01A	90 years, female, stage:iii, alive, 638 days	5708.4
TCGA-AG-3593-01A	72 years, female, stage:iia, alive, 1035 days	5674.7
TCGA-F5-6811-01A	72 years, female, white, stage:iia, alive, 979 days	5652.8
TCGA-AH-6547-01A	79 years, female, white, dead, 76 days	5618.3
TCGA-CI-6623-01B	44 years, male, white, stage:i, alive, 1443 days	5579.0
TCGA-AH-6903-01A	46 years, male, white, stage:iiib, alive, 592 days	5575.4
TCGA-F5-6571-01A	62 years, female, white, stage:iia, alive, 1288 days	5571.8
TCGA-F5-6702-01A	71 years, male, white, stage:iva, alive, 869 days	5569.3
TCGA-AG-3574-01A	89 years, female, stage:ii, dead, 1096 days	5551.9
TCGA-AG-3583-01A	66 years, male, stage:iv, dead, 610 days	5509.5
TCGA-AG-A00C-01A	49 years, female, stage:iiib, alive, 183 days	5483.0
TCGA-AG-3901-01A	67 years, female, stage:iiib, alive, 761 days	5438.6
TCGA-AG-3893-01A	74 years, male, stage:iiib, alive, 1065 days	5378.6
TCGA-AF-2690-01A	77 years, female, white, stage:iiic, dead, 524 days	5318.3
TCGA-DC-6157-01A	48 years, male, black or african american, stage:i, alive, 1581 days	5297.2
TCGA-AF-3911-01A	48 years, male, white, stage:iiic, alive, 1148 days	5238.2
TCGA-EI-6506-01A	78 years, female, white, stage:iia, alive, 625 days	5188.0
TCGA-DT-5265-01A	51 years, male, asian, stage:ii, alive, 384 days	5144.5
TCGA-AF-2691-01A	48 years, female, white, stage:i, alive, 1309 days	5075.2
TCGA-AG-A036-01A	71 years, male, stage:iii, alive, 3562 days	5056.8
TCGA-AH-6643-01A	50 years, male, white, stage:iiic, dead, 1314 days	5051.0
TCGA-AG-3578-01A	76 years, female, stage:iia, alive, 974 days	4980.9
TCGA-AG-A008-01A	50 years, female, stage:i, alive, 424 days	4957.8
TCGA-AF-4110-01A	77 years, male, white, stage:iva, alive, 912 days	4934.4
TCGA-F5-6464-01A	77 years, female, white, stage:iiic, dead, 303 days	4886.0
TCGA-AG-4008-01A	63 years, male, stage:iia, alive, 518 days	4848.1
TCGA-AF-A56N-01A	47 years, female, black or african american, stage:iia, alive, 360 days	4799.7
TCGA-DC-6683-01A	43 years, male, white, stage:iiib, alive, 762 days	4732.5
TCGA-AF-2693-01A	75 years, male, white, stage:i, alive, 1155 days	4712.8
TCGA-DC-6160-01A	68 years, male, white, stage:i, alive, 1339 days	4606.1
TCGA-DY-A0XA-01A	57 years, female, white, stage:iia, alive, 3846 days	4582.5
TCGA-AG-A014-01A	86 years, male, stage:i, alive, 485 days	4506.7
TCGA-CI-6619-01B	41 years, male, white, stage:iv, alive, 184 days	4454.2
TCGA-EF-5831-01A	72 years, male, white, stage:iia, alive, 127 days	4305.0
TCGA-AG-4022-01A	59 years, female, stage:ii, alive, 1400 days	4242.8
TCGA-AG-3887-01A	68 years, male, stage:iia, alive, 1124 days	4221.6
TCGA-DY-A1DE-01A	56 years, female, white, stage:iia, alive, 3932 days	4097.5
TCGA-AG-A023-01A	62 years, female, stage:iv, dead, 1581 days	4024.9
TCGA-EI-6511-01A	52 years, male, white, stage:iiib, alive, 482 days	3997.3
TCGA-AG-A02N-01A	67 years, male, stage:ii, alive, 1885 days	3990.5
TCGA-AF-6136-01A	72 years, female, white, stage:iiib, alive, 741 days	3944.1
TCGA-AG-3580-01A	67 years, male, stage:i, alive, 244 days	3908.0
TCGA-DC-6155-01A	31 years, female, white, stage:iiia, alive, 425 days	3879.9
TCGA-EI-6881-01A	60 years, male, white, stage:iiia, alive, 499 days	3863.1
TCGA-AH-6644-01A	73 years, male, white, alive, 838 days	3787.9
TCGA-AF-2687-01A	57 years, male, white, stage:iiic, alive, 1427 days	3779.8
TCGA-AG-3591-01A	66 years, female, stage:iia, alive, 1035 days	3773.1
TCGA-AG-A01N-01A	68 years, female, stage:iv, alive, 943 days	3772.2
TCGA-AG-4001-01A	74 years, female, stage:iia, alive, 1096 days	3759.5
TCGA-AG-3581-01A	63 years, male, stage:i, alive, 215 days	3754.4
TCGA-AG-3605-01A	85 years, female, stage:iv, alive, 30 days	3750.5
TCGA-AF-2692-01A	54 years, female, white, stage:iia, alive, 412 days	3666.6
TCGA-CL-4957-01A	79 years, female, dead, 425 days	3655.4
TCGA-AG-3909-01A	69 years, female, stage:iiib, alive, 608 days	3644.9
TCGA-AG-4021-01A	84 years, female, stage:iv, dead, 121 days	3642.9
TCGA-AG-3882-01A	66 years, female, stage:i, alive, 608 days	3544.8
TCGA-G5-6233-01A	74 years, male, white, dead, 556 days	3525.5
TCGA-CI-6620-01A	41 years, female, white, stage:iva, alive, 1009 days	3508.2
TCGA-AG-4007-01A	87 years, male, stage:iv, alive, 31 days	3492.6
TCGA-AG-3896-01A	85 years, female, stage:i, alive, 31 days	3430.4
TCGA-CI-6622-01A	74 years, male, white, stage:iib, alive, 1362 days	3426.7
TCGA-AG-3612-01A	55 years, female, stage:iiib, alive, 608 days	3416.4
TCGA-AF-A56L-01A	48 years, female, black or african american, stage:iiic, alive, 2007 days	3415.7
TCGA-AG-3584-01A	60 years, male, stage:iv, dead, 730 days	3408.4
TCGA-AG-3892-01A	57 years, female, stage:i, alive, 396 days	3408.3
TCGA-AG-A025-01A	62 years, female, stage:i, alive, 1520 days	3406.9
TCGA-AG-3999-01A	61 years, female, stage:iiic, alive, 853 days	3373.8
TCGA-AG-3592-01A	68 years, male, stage:iia, alive, 1035 days	3300.9
TCGA-EI-6513-01A	59 years, male, white, stage:iiib, alive, 497 days	3281.9
TCGA-AG-3731-01A	65 years, male, stage:iv, alive, 1126 days	3159.3
TCGA-AG-3608-01A	79 years, female, stage:iia, alive, 485 days	3041.0
TCGA-F5-6814-01A	57 years, male, white, stage:iia, alive, 1131 days	3011.6
TCGA-AG-3611-01A	72 years, male, stage:iia, alive, 424 days	2908.6
TCGA-AF-3913-01A	60 years, male, black or african american, stage:iv, dead, 316 days	2887.4
TCGA-AG-3894-01A	65 years, male, stage:iia, alive, 426 days	2768.9
TCGA-DC-4749-01A	57 years, male, white, stage:i, alive, 762 days	2720.0
TCGA-AG-A020-01A	57 years, female, stage:iii, alive, 31 days	2594.9
TCGA-EI-6508-01A	48 years, female, white, stage:iiib, alive, 636 days	2593.2
TCGA-EI-6512-01A	64 years, female, white, stage:iiib, alive, 538 days	2542.4
TCGA-AF-3400-01A	54 years, male, white, stage:iia, alive, 1049 days	2530.8
TCGA-AF-6655-01A	66 years, male, white, stage:iiia, alive, 609 days	2530.7
TCGA-AG-A016-01A	55 years, male, stage:iv, alive, 276 days	2451.9
TCGA-AG-3586-01A	72 years, female, stage:iii, alive, 31 days	2405.8
TCGA-DC-6681-01A	70 years, female, white, stage:iva, alive, 790 days	2399.7
TCGA-AG-3902-01A	61 years, male, stage:iia, alive, 974 days	2327.3
TCGA-AG-3878-01A	64 years, male, stage:i, alive, 30 days	2318.2
TCGA-AG-3594-01A	77 years, male, stage:iia, dead, 61 days	2297.4
TCGA-F5-6861-01A	60 years, female, white, stage:iia, alive, 1160 days	2296.2
TCGA-AG-3609-01A	65 years, female, stage:iiic, alive, 608 days	2283.6
TCGA-F5-6864-01A	74 years, female, white, stage:iiib, alive, 379 days	2248.6
TCGA-DC-6156-01A	62 years, male, white, stage:iva, alive, 943 days	2226.2
TCGA-DC-6158-01A	70 years, male, white, stage:i, dead, 334 days	2206.8
TCGA-AG-3598-01A	69 years, male, stage:iia, alive, 1522 days	2192.4
TCGA-AG-3599-01A	70 years, male, stage:i, alive, 366 days	2143.9
TCGA-AG-3582-01A	75 years, male, stage:iv, dead, 1096 days	2089.5
TCGA-AG-4005-01A	64 years, male, stage:iv, alive, 427 days	2085.2
TCGA-AH-6549-01A	66 years, male, white, alive, 532 days	1989.1
TCGA-AG-3728-01A	73 years, male, stage:iiib, alive, 912 days	1967.4
TCGA-F5-6863-01A	71 years, female, white, stage:iiib, dead, 361 days	1955.4
TCGA-EI-6883-01A	63 years, male, white, stage:iic, alive, 350 days	1840.3
TCGA-AG-3885-01A	71 years, female, stage:iiib, alive, 546 days	1821.3
TCGA-EI-7002-01A	58 years, male, white, stage:iv, alive, 364 days	1777.7
TCGA-AG-A02X-01A	77 years, male, stage:i, alive, 1247 days	1773.7
TCGA-DC-6154-01A	57 years, female, white, stage:iva, alive, 365 days	1743.0
TCGA-DC-5869-01A	62 years, female, black or african american, stage:iiib, alive, 943 days	1652.9
TCGA-DC-4745-01A	49 years, female, white, stage:iiib, alive, 639 days	1651.0
TCGA-EI-6884-01A	71 years, male, white, stage:iiia, alive, 328 days	1640.7
TCGA-AG-3883-01A	69 years, male, stage:i, alive, 31 days	1553.8
TCGA-AH-6897-01A	48 years, male, white, stage:i, alive, 804 days	1512.9
TCGA-EI-6885-01A	57 years, female, white, stage:iv, alive, 415 days	1398.7
TCGA-AG-3587-01A	65 years, male, stage:i, alive, 1400 days	1325.0
TCGA-EI-6507-01A	60 years, male, white, stage:iia, alive, 607 days	1313.4
TCGA-EI-6882-01A	59 years, male, white, stage:iia, alive, 262 days	1129.5
TCGA-AG-3881-01A	83 years, female, stage:iia, alive, 579 days	1096.4
TCGA-AG-3575-01A	51 years, male, stage:ii, alive, 365 days	992.8
TCGA-DC-5337-01A	69 years, male, white, stage:i, alive, 792 days	979.9
TCGA-EI-6917-01A	33 years, male, white, stage:iiia, alive, 531 days	967.4
TCGA-AG-3726-01A	63 years, female, stage:i, alive, 243 days	658.4
TCGA-EI-7004-01A	37 years, female, white, alive, 257 days	543.4
TCGA-AG-3727-01A	78 years, female, stage:iii, alive, 30 days	288.8
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