Expression of TMSB4X in colorectal cancer

RECTUM ADENOCARCINOMA (READ) - Interactive survival scatter plotⁱ

The Survival Scatter plot shows the clinical status (i.e. dead or alive) for all individuals in the patient cohort, based on the same data that underlies the corresponding Kaplan-Meier plots. Patients that are alive at last time for follow-up are shown in blue and patients who have died during the study are shown in red.

The x-axis shows the expression levels (FPKM) of the investigated gene in the tumor tissue at the time of diagnosis. The y-axis shows the follow-up time after diagnosis (years). Both axes are complimented with kernel density curves demonstrating the data density over the axes. The top density plot shows the expression levels (FPKM) distribution among dead (red) and alive patients (blue). The right density plot shows the data density of the survived years of dead patients with high and low expression levels respectively, stratified using the cutoff indicated by the vertical dashed line through the Survival Scatter plot. This cutoff is automatically defined based on the FPKM cutoff that minimizes the p-score. The cutoff can be changed by dragging the vertical line or by entering a cutoff value in the square labeled "Current cut-off".

Under the Survival Scatter plot the p-score landscape (black curve; left axis) is shown together with dead median separation (red curve; right axis). Dead median separation is the difference in median mRNA expression between patients who have died with high and low expression, respectively. It is calculated as follows: median FPKM expression of dead patients with high expression - median FPKM expression of dead patients with low expression. This is intended to aid the user in visually exploring custom cutoffs and the associated p-scores and dead median separation.

Individual patient data is displayed and can be filtered by clicking on one or more of the category buttons on the top of the page. Categories describing expression level and patient information include: high, low, alive, dead, female, male and tumor stages. The scale of the x-axis can be toggled between linear and log-scale by clicking on the "x log" button. Mouse-over function shows TCGA ID, patient information and mRNA expression (FPKM) for each patient.

& Survival analysisⁱ

Stage:

Survival analysis

Current cut offⁱ:
Best expression cut offⁱ: 842.65
Median expressionⁱ: N/A
Median follow up timeⁱ: N/A
P scoreⁱ N/A
5-year survival highⁱ N/A
5-year survival lowⁱ N/A

TCGA RNA samplesⁱ

Average FPKM

1026.8

Number of samples

159

Samples

Sample	Description	FPKM
TCGA-DC-5337-01A	69 years, male, white, stage:i, alive, 792 days	3947.5
TCGA-AG-3591-01A	66 years, female, stage:iia, alive, 1035 days	2756.4
TCGA-F5-6811-01A	72 years, female, white, stage:iia, alive, 979 days	2535.2
TCGA-AG-3883-01A	69 years, male, stage:i, alive, 31 days	2459.6
TCGA-AG-3575-01A	51 years, male, stage:ii, alive, 365 days	2449.6
TCGA-AF-A56N-01A	47 years, female, black or african american, stage:iia, alive, 360 days	2224.3
TCGA-DC-5869-01A	62 years, female, black or african american, stage:iiib, alive, 943 days	2170.6
TCGA-DC-4745-01A	49 years, female, white, stage:iiib, alive, 639 days	2121.1
TCGA-AG-3898-01A	61 years, male, stage:iia, alive, 1461 days	1968.2
TCGA-AH-6897-01A	48 years, male, white, stage:i, alive, 804 days	1941.1
TCGA-DC-6154-01A	57 years, female, white, stage:iva, alive, 365 days	1825.3
TCGA-CL-5918-01A	90 years, female, white, stage:iia, alive, 218 days	1716.8
TCGA-AH-6544-01A	60 years, male, white, alive, 1173 days	1716.4
TCGA-DT-5265-01A	51 years, male, asian, stage:ii, alive, 384 days	1695.9
TCGA-AG-A00C-01A	49 years, female, stage:iiib, alive, 183 days	1695.2
TCGA-EI-7002-01A	58 years, male, white, stage:iv, alive, 364 days	1602.0
TCGA-AG-3892-01A	57 years, female, stage:i, alive, 396 days	1594.0
TCGA-AG-3728-01A	73 years, male, stage:iiib, alive, 912 days	1565.1
TCGA-DC-6158-01A	70 years, male, white, stage:i, dead, 334 days	1539.6
TCGA-AG-4021-01A	84 years, female, stage:iv, dead, 121 days	1511.3
TCGA-AG-3742-01A	85 years, female, stage:i, alive, 30 days	1466.4
TCGA-G5-6235-01A	72 years, male, white, stage:iiib, alive, 1696 days	1439.3
TCGA-AG-3582-01A	75 years, male, stage:iv, dead, 1096 days	1404.1
TCGA-DC-4749-01A	57 years, male, white, stage:i, alive, 762 days	1393.9
TCGA-EI-6511-01A	52 years, male, white, stage:iiib, alive, 482 days	1388.6
TCGA-AG-3605-01A	85 years, female, stage:iv, alive, 30 days	1365.1
TCGA-AG-3592-01A	68 years, male, stage:iia, alive, 1035 days	1354.9
TCGA-AG-3893-01A	74 years, male, stage:iiib, alive, 1065 days	1338.9
TCGA-DY-A1DG-01A	75 years, male, white, stage:iva, dead, 1566 days	1328.0
TCGA-CI-6620-01A	41 years, female, white, stage:iva, alive, 1009 days	1254.9
TCGA-EI-6508-01A	48 years, female, white, stage:iiib, alive, 636 days	1254.2
TCGA-AF-3913-01A	60 years, male, black or african american, stage:iv, dead, 316 days	1250.1
TCGA-AF-2690-01A	77 years, female, white, stage:iiic, dead, 524 days	1239.3
TCGA-AF-3911-01A	48 years, male, white, stage:iiic, alive, 1148 days	1238.5
TCGA-AG-3587-01A	65 years, male, stage:i, alive, 1400 days	1230.4
TCGA-DY-A1DF-01A	73 years, female, white, stage:iiic, dead, 734 days	1230.3
TCGA-AG-A032-01A	68 years, male, stage:iiib, alive, 1157 days	1220.0
TCGA-EI-6514-01A	59 years, female, white, stage:iia, alive, 496 days	1214.9
TCGA-AG-3598-01A	69 years, male, stage:iia, alive, 1522 days	1214.9
TCGA-F5-6702-01A	71 years, male, white, stage:iva, alive, 869 days	1208.4
TCGA-AF-A56K-01A	56 years, male, black or african american, stage:iia, alive, 2635 days	1204.6
TCGA-AG-3611-01A	72 years, male, stage:iia, alive, 424 days	1200.6
TCGA-DC-6683-01A	43 years, male, white, stage:iiib, alive, 762 days	1200.0
TCGA-AG-3583-01A	66 years, male, stage:iv, dead, 610 days	1196.8
TCGA-AF-3400-01A	54 years, male, white, stage:iia, alive, 1049 days	1195.7
TCGA-DY-A1H8-01A	77 years, female, white, stage:iiia, dead, 992 days	1186.2
TCGA-AG-3574-01A	89 years, female, stage:ii, dead, 1096 days	1184.7
TCGA-EI-6512-01A	64 years, female, white, stage:iiib, alive, 538 days	1180.5
TCGA-AG-4022-01A	59 years, female, stage:ii, alive, 1400 days	1167.7
TCGA-AG-3608-01A	79 years, female, stage:iia, alive, 485 days	1165.9
TCGA-EI-6881-01A	60 years, male, white, stage:iiia, alive, 499 days	1151.9
TCGA-AG-3896-01A	85 years, female, stage:i, alive, 31 days	1112.9
TCGA-AG-3599-01A	70 years, male, stage:i, alive, 366 days	1107.2
TCGA-G5-6641-01A	67 years, male, white, stage:iiia, alive, 804 days	1107.0
TCGA-AG-4007-01A	87 years, male, stage:iv, alive, 31 days	1098.9
TCGA-DC-6156-01A	62 years, male, white, stage:iva, alive, 943 days	1098.4
TCGA-AF-A56L-01A	48 years, female, black or african american, stage:iiic, alive, 2007 days	1090.3
TCGA-F5-6465-01A	64 years, female, white, stage:iia, alive, 1506 days	1065.3
TCGA-BM-6198-01A	73 years, male, white, stage:iiib, alive, 646 days	1052.5
TCGA-AG-A023-01A	62 years, female, stage:iv, dead, 1581 days	1027.4
TCGA-AG-3594-01A	77 years, male, stage:iia, dead, 61 days	1021.1
TCGA-AH-6903-01A	46 years, male, white, stage:iiib, alive, 592 days	1017.8
TCGA-AF-2687-01A	57 years, male, white, stage:iiic, alive, 1427 days	1001.3
TCGA-AF-6655-01A	66 years, male, white, stage:iiia, alive, 609 days	983.1
TCGA-AG-A00H-01A	75 years, male, stage:iia, alive, 790 days	979.3
TCGA-AG-3901-01A	67 years, female, stage:iiib, alive, 761 days	970.9
TCGA-EI-7004-01A	37 years, female, white, alive, 257 days	967.6
TCGA-EF-5831-01A	72 years, male, white, stage:iia, alive, 127 days	956.3
TCGA-CI-6624-01C	53 years, female, white, stage:i, alive, 1466 days	955.0
TCGA-AG-3902-01A	61 years, male, stage:iia, alive, 974 days	953.4
TCGA-AF-6136-01A	72 years, female, white, stage:iiib, alive, 741 days	952.5
TCGA-F5-6464-01A	77 years, female, white, stage:iiic, dead, 303 days	952.0
TCGA-F5-6861-01A	60 years, female, white, stage:iia, alive, 1160 days	949.8
TCGA-DC-6160-01A	68 years, male, white, stage:i, alive, 1339 days	945.9
TCGA-DY-A0XA-01A	57 years, female, white, stage:iia, alive, 3846 days	943.7
TCGA-DC-6681-01A	70 years, female, white, stage:iva, alive, 790 days	937.9
TCGA-AG-3725-01A	90 years, female, stage:iii, alive, 638 days	933.9
TCGA-AG-3593-01A	72 years, female, stage:iia, alive, 1035 days	928.3
TCGA-AG-3999-01A	61 years, female, stage:iiic, alive, 853 days	909.9
TCGA-AG-3894-01A	65 years, male, stage:iia, alive, 426 days	906.2
TCGA-F5-6863-01A	71 years, female, white, stage:iiib, dead, 361 days	905.3
TCGA-AG-4008-01A	63 years, male, stage:iia, alive, 518 days	904.9
TCGA-EI-6884-01A	71 years, male, white, stage:iiia, alive, 328 days	899.1
TCGA-AG-3612-01A	55 years, female, stage:iiib, alive, 608 days	896.3
TCGA-AG-A01J-01A	59 years, female, stage:iia, alive, 31 days	893.2
TCGA-AF-4110-01A	77 years, male, white, stage:iva, alive, 912 days	891.4
TCGA-AF-2693-01A	75 years, male, white, stage:i, alive, 1155 days	884.5
TCGA-AG-3600-01A	62 years, male, stage:iiic, alive, 184 days	873.9
TCGA-CL-4957-01A	79 years, female, dead, 425 days	872.7
TCGA-G5-6233-01A	74 years, male, white, dead, 556 days	849.9
TCGA-AH-6643-01A	50 years, male, white, stage:iiic, dead, 1314 days	848.3
TCGA-DY-A1DC-01A	72 years, female, white, stage:iia, dead, 1258 days	844.0
TCGA-AF-2691-01A	48 years, female, white, stage:i, alive, 1309 days	843.5
TCGA-AH-6547-01A	79 years, female, white, dead, 76 days	842.8
TCGA-AF-5654-01A	73 years, female, white, stage:i, dead, 512 days	842.7
TCGA-CI-6622-01A	74 years, male, white, stage:iib, alive, 1362 days	842.6
TCGA-AG-3731-01A	65 years, male, stage:iv, alive, 1126 days	838.9
TCGA-EI-6513-01A	59 years, male, white, stage:iiib, alive, 497 days	836.9
TCGA-DC-6682-01A	57 years, male, white, stage:iia, alive, 762 days	831.4
TCGA-AG-3878-01A	64 years, male, stage:i, alive, 30 days	829.4
TCGA-AF-6672-01A	43 years, male, white, stage:iv, alive, 748 days	826.4
TCGA-F5-6864-01A	74 years, female, white, stage:iiib, alive, 379 days	820.6
TCGA-AG-3578-01A	76 years, female, stage:iia, alive, 974 days	809.0
TCGA-AG-3882-01A	66 years, female, stage:i, alive, 608 days	803.0
TCGA-AG-A02N-01A	67 years, male, stage:ii, alive, 1885 days	800.8
TCGA-EF-5830-01A	54 years, male, white, stage:iib, alive, 106 days	792.8
TCGA-AF-2692-01A	54 years, female, white, stage:iia, alive, 412 days	788.4
TCGA-AG-A01N-01A	68 years, female, stage:iv, alive, 943 days	774.0
TCGA-F5-6812-01A	67 years, male, white, stage:iia, alive, 1110 days	771.2
TCGA-CI-6621-01A	63 years, male, white, stage:iiib, alive, 419 days	771.0
TCGA-DY-A1DE-01A	56 years, female, white, stage:iia, alive, 3932 days	770.1
TCGA-AH-6549-01A	66 years, male, white, alive, 532 days	763.6
TCGA-AH-6644-01A	73 years, male, white, alive, 838 days	752.2
TCGA-CL-5917-01A	71 years, female, white, stage:iiic, alive, 2376 days	748.9
TCGA-AG-A020-01A	57 years, female, stage:iii, alive, 31 days	744.0
TCGA-AG-3909-01A	69 years, female, stage:iiib, alive, 608 days	724.3
TCGA-AG-4001-01A	74 years, female, stage:iia, alive, 1096 days	721.1
TCGA-AG-A015-01A	64 years, female, stage:i, alive, 1096 days	711.4
TCGA-DC-6157-01A	48 years, male, black or african american, stage:i, alive, 1581 days	710.0
TCGA-AG-3609-01A	65 years, female, stage:iiic, alive, 608 days	707.9
TCGA-AG-A025-01A	62 years, female, stage:i, alive, 1520 days	705.8
TCGA-AG-3881-01A	83 years, female, stage:iia, alive, 579 days	699.3
TCGA-AG-3586-01A	72 years, female, stage:iii, alive, 31 days	695.7
TCGA-EI-6917-01A	33 years, male, white, stage:iiia, alive, 531 days	693.7
TCGA-AG-3890-01A	62 years, male, stage:i, alive, 518 days	674.4
TCGA-F5-6813-01A	70 years, male, white, stage:iiic, dead, 598 days	667.7
TCGA-AG-3580-01A	67 years, male, stage:i, alive, 244 days	665.0
TCGA-AG-A00Y-01A	68 years, male, stage:iia, alive, 700 days	654.8
TCGA-AG-A008-01A	50 years, female, stage:i, alive, 424 days	651.8
TCGA-F5-6571-01A	62 years, female, white, stage:iia, alive, 1288 days	645.0
TCGA-AG-4005-01A	64 years, male, stage:iv, alive, 427 days	643.1
TCGA-AG-A026-01A	66 years, male, stage:ii, dead, 59 days	640.9
TCGA-AG-3726-01A	63 years, female, stage:i, alive, 243 days	631.8
TCGA-EI-6510-01A	77 years, female, white, alive, 556 days	631.3
TCGA-G5-6572-01A	56 years, male, white, dead, 1432 days	626.1
TCGA-AG-A02X-01A	77 years, male, stage:i, alive, 1247 days	617.0
TCGA-EI-6506-01A	78 years, female, white, stage:iia, alive, 625 days	614.8
TCGA-CI-6619-01B	41 years, male, white, stage:iv, alive, 184 days	599.9
TCGA-AG-A014-01A	86 years, male, stage:i, alive, 485 days	599.6
TCGA-EI-6883-01A	63 years, male, white, stage:iic, alive, 350 days	591.7
TCGA-AG-3885-01A	71 years, female, stage:iiib, alive, 546 days	591.0
TCGA-EI-6882-01A	59 years, male, white, stage:iia, alive, 262 days	587.7
TCGA-AG-3887-01A	68 years, male, stage:iia, alive, 1124 days	567.9
TCGA-AG-3581-01A	63 years, male, stage:i, alive, 215 days	566.6
TCGA-CI-6623-01B	44 years, male, white, stage:i, alive, 1443 days	552.9
TCGA-EI-6885-01A	57 years, female, white, stage:iv, alive, 415 days	552.6
TCGA-AG-3732-01A	78 years, female, stage:i, alive, 1003 days	548.1
TCGA-AG-3584-01A	60 years, male, stage:iv, dead, 730 days	492.8
TCGA-DC-6155-01A	31 years, female, white, stage:iiia, alive, 425 days	485.1
TCGA-F5-6814-01A	57 years, male, white, stage:iia, alive, 1131 days	479.8
TCGA-EI-6507-01A	60 years, male, white, stage:iia, alive, 607 days	440.2
TCGA-EI-6509-01A	53 years, male, white, stage:iiic, alive, 517 days	439.0
TCGA-AG-A02G-01A	66 years, male, stage:iv, dead, 1185 days	410.9
TCGA-AG-A036-01A	71 years, male, stage:iii, alive, 3562 days	380.9
TCGA-AG-3727-01A	78 years, female, stage:iii, alive, 30 days	366.5
TCGA-DY-A1DD-01A	77 years, female, white, stage:iiib, dead, 1741 days	327.7
TCGA-AG-A011-01A	80 years, male, stage:iia, alive, 1126 days	323.3
TCGA-AG-A016-01A	55 years, male, stage:iv, alive, 276 days	304.2
TCGA-AG-A002-01A	35 years, male, stage:i, alive, 638 days	296.0
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