Expression of RPS18 in colorectal cancer

RECTUM ADENOCARCINOMA (READ) - Interactive survival scatter plotⁱ

The Survival Scatter plot shows the clinical status (i.e. dead or alive) for all individuals in the patient cohort, based on the same data that underlies the corresponding Kaplan-Meier plots. Patients that are alive at last time for follow-up are shown in blue and patients who have died during the study are shown in red.

The x-axis shows the expression levels (FPKM) of the investigated gene in the tumor tissue at the time of diagnosis. The y-axis shows the follow-up time after diagnosis (years). Both axes are complimented with kernel density curves demonstrating the data density over the axes. The top density plot shows the expression levels (FPKM) distribution among dead (red) and alive patients (blue). The right density plot shows the data density of the survived years of dead patients with high and low expression levels respectively, stratified using the cutoff indicated by the vertical dashed line through the Survival Scatter plot. This cutoff is automatically defined based on the FPKM cutoff that minimizes the p-score. The cutoff can be changed by dragging the vertical line or by entering a cutoff value in the square labeled "Current cut-off".

Under the Survival Scatter plot the p-score landscape (black curve; left axis) is shown together with dead median separation (red curve; right axis). Dead median separation is the difference in median mRNA expression between patients who have died with high and low expression, respectively. It is calculated as follows: median FPKM expression of dead patients with high expression - median FPKM expression of dead patients with low expression. This is intended to aid the user in visually exploring custom cutoffs and the associated p-scores and dead median separation.

Individual patient data is displayed and can be filtered by clicking on one or more of the category buttons on the top of the page. Categories describing expression level and patient information include: high, low, alive, dead, female, male and tumor stages. The scale of the x-axis can be toggled between linear and log-scale by clicking on the "x log" button. Mouse-over function shows TCGA ID, patient information and mRNA expression (FPKM) for each patient.

& Survival analysisⁱ

Stage:

Survival analysis

Current cut offⁱ:
Best expression cut offⁱ: 880.59
Median expressionⁱ: N/A
Median follow up timeⁱ: N/A
P scoreⁱ N/A
5-year survival highⁱ N/A
5-year survival lowⁱ N/A

TCGA RNA samplesⁱ

Average FPKM

1342.6

Number of samples

159

Samples

Sample	Description	FPKM
TCGA-AG-3591-01A	66 years, female, stage:iia, alive, 1035 days	5241.6
TCGA-AG-3883-01A	69 years, male, stage:i, alive, 31 days	4025.6
TCGA-AG-3881-01A	83 years, female, stage:iia, alive, 579 days	3339.0
TCGA-AG-3583-01A	66 years, male, stage:iv, dead, 610 days	3230.1
TCGA-AG-3605-01A	85 years, female, stage:iv, alive, 30 days	3052.8
TCGA-DC-6682-01A	57 years, male, white, stage:iia, alive, 762 days	2931.9
TCGA-AG-3598-01A	69 years, male, stage:iia, alive, 1522 days	2892.7
TCGA-DC-4745-01A	49 years, female, white, stage:iiib, alive, 639 days	2663.9
TCGA-AG-3728-01A	73 years, male, stage:iiib, alive, 912 days	2550.8
TCGA-AG-3611-01A	72 years, male, stage:iia, alive, 424 days	2498.0
TCGA-DC-5337-01A	69 years, male, white, stage:i, alive, 792 days	2477.8
TCGA-AG-3609-01A	65 years, female, stage:iiic, alive, 608 days	2472.5
TCGA-AG-3999-01A	61 years, female, stage:iiic, alive, 853 days	2323.5
TCGA-DC-5869-01A	62 years, female, black or african american, stage:iiib, alive, 943 days	2308.0
TCGA-AG-3574-01A	89 years, female, stage:ii, dead, 1096 days	2297.3
TCGA-AG-3575-01A	51 years, male, stage:ii, alive, 365 days	2218.8
TCGA-DY-A1DG-01A	75 years, male, white, stage:iva, dead, 1566 days	2194.8
TCGA-AG-3892-01A	57 years, female, stage:i, alive, 396 days	2186.5
TCGA-AG-3882-01A	66 years, female, stage:i, alive, 608 days	2070.8
TCGA-AG-4005-01A	64 years, male, stage:iv, alive, 427 days	2061.9
TCGA-AG-3896-01A	85 years, female, stage:i, alive, 31 days	2008.7
TCGA-AG-A02G-01A	66 years, male, stage:iv, dead, 1185 days	2007.2
TCGA-AG-3608-01A	79 years, female, stage:iia, alive, 485 days	1998.5
TCGA-AG-3587-01A	65 years, male, stage:i, alive, 1400 days	1959.4
TCGA-AF-2693-01A	75 years, male, white, stage:i, alive, 1155 days	1942.5
TCGA-AF-2691-01A	48 years, female, white, stage:i, alive, 1309 days	1928.7
TCGA-EF-5830-01A	54 years, male, white, stage:iib, alive, 106 days	1830.3
TCGA-AF-3911-01A	48 years, male, white, stage:iiic, alive, 1148 days	1826.0
TCGA-DY-A1H8-01A	77 years, female, white, stage:iiia, dead, 992 days	1815.2
TCGA-AG-3887-01A	68 years, male, stage:iia, alive, 1124 days	1793.6
TCGA-AG-3612-01A	55 years, female, stage:iiib, alive, 608 days	1792.4
TCGA-DY-A0XA-01A	57 years, female, white, stage:iia, alive, 3846 days	1768.0
TCGA-AG-4007-01A	87 years, male, stage:iv, alive, 31 days	1754.5
TCGA-AG-3894-01A	65 years, male, stage:iia, alive, 426 days	1753.6
TCGA-AG-3581-01A	63 years, male, stage:i, alive, 215 days	1740.5
TCGA-AG-3885-01A	71 years, female, stage:iiib, alive, 546 days	1711.6
TCGA-G5-6233-01A	74 years, male, white, dead, 556 days	1710.7
TCGA-DC-6154-01A	57 years, female, white, stage:iva, alive, 365 days	1697.8
TCGA-AG-3725-01A	90 years, female, stage:iii, alive, 638 days	1656.7
TCGA-AF-4110-01A	77 years, male, white, stage:iva, alive, 912 days	1611.9
TCGA-EI-7002-01A	58 years, male, white, stage:iv, alive, 364 days	1543.5
TCGA-AF-6136-01A	72 years, female, white, stage:iiib, alive, 741 days	1536.5
TCGA-AH-6549-01A	66 years, male, white, alive, 532 days	1526.5
TCGA-AG-3727-01A	78 years, female, stage:iii, alive, 30 days	1511.5
TCGA-AG-3592-01A	68 years, male, stage:iia, alive, 1035 days	1493.1
TCGA-AF-3913-01A	60 years, male, black or african american, stage:iv, dead, 316 days	1478.5
TCGA-AH-6644-01A	73 years, male, white, alive, 838 days	1407.9
TCGA-AG-A023-01A	62 years, female, stage:iv, dead, 1581 days	1402.3
TCGA-AF-6672-01A	43 years, male, white, stage:iv, alive, 748 days	1397.5
TCGA-DY-A1DD-01A	77 years, female, white, stage:iiib, dead, 1741 days	1396.8
TCGA-AG-3600-01A	62 years, male, stage:iiic, alive, 184 days	1384.5
TCGA-CI-6623-01B	44 years, male, white, stage:i, alive, 1443 days	1377.6
TCGA-AG-A00Y-01A	68 years, male, stage:iia, alive, 700 days	1375.3
TCGA-AG-3902-01A	61 years, male, stage:iia, alive, 974 days	1374.1
TCGA-EI-6917-01A	33 years, male, white, stage:iiia, alive, 531 days	1354.1
TCGA-AG-A015-01A	64 years, female, stage:i, alive, 1096 days	1348.8
TCGA-BM-6198-01A	73 years, male, white, stage:iiib, alive, 646 days	1330.8
TCGA-F5-6863-01A	71 years, female, white, stage:iiib, dead, 361 days	1315.5
TCGA-F5-6571-01A	62 years, female, white, stage:iia, alive, 1288 days	1310.3
TCGA-AG-A02X-01A	77 years, male, stage:i, alive, 1247 days	1301.7
TCGA-AG-3586-01A	72 years, female, stage:iii, alive, 31 days	1297.5
TCGA-AG-A00C-01A	49 years, female, stage:iiib, alive, 183 days	1287.7
TCGA-CL-5918-01A	90 years, female, white, stage:iia, alive, 218 days	1285.7
TCGA-AG-4022-01A	59 years, female, stage:ii, alive, 1400 days	1267.6
TCGA-AG-3582-01A	75 years, male, stage:iv, dead, 1096 days	1266.8
TCGA-AG-A016-01A	55 years, male, stage:iv, alive, 276 days	1265.2
TCGA-G5-6641-01A	67 years, male, white, stage:iiia, alive, 804 days	1263.7
TCGA-DC-4749-01A	57 years, male, white, stage:i, alive, 762 days	1261.4
TCGA-CI-6621-01A	63 years, male, white, stage:iiib, alive, 419 days	1240.1
TCGA-AF-A56L-01A	48 years, female, black or african american, stage:iiic, alive, 2007 days	1227.5
TCGA-AF-5654-01A	73 years, female, white, stage:i, dead, 512 days	1224.5
TCGA-AG-A025-01A	62 years, female, stage:i, alive, 1520 days	1222.6
TCGA-EI-6881-01A	60 years, male, white, stage:iiia, alive, 499 days	1209.4
TCGA-AG-3878-01A	64 years, male, stage:i, alive, 30 days	1191.1
TCGA-AG-3726-01A	63 years, female, stage:i, alive, 243 days	1189.2
TCGA-DY-A1DC-01A	72 years, female, white, stage:iia, dead, 1258 days	1179.2
TCGA-EI-6509-01A	53 years, male, white, stage:iiic, alive, 517 days	1177.7
TCGA-F5-6814-01A	57 years, male, white, stage:iia, alive, 1131 days	1175.6
TCGA-CI-6619-01B	41 years, male, white, stage:iv, alive, 184 days	1171.1
TCGA-AG-3580-01A	67 years, male, stage:i, alive, 244 days	1164.4
TCGA-AH-6544-01A	60 years, male, white, alive, 1173 days	1164.3
TCGA-AG-A01N-01A	68 years, female, stage:iv, alive, 943 days	1163.6
TCGA-DY-A1DE-01A	56 years, female, white, stage:iia, alive, 3932 days	1162.3
TCGA-DC-6155-01A	31 years, female, white, stage:iiia, alive, 425 days	1161.1
TCGA-DC-6681-01A	70 years, female, white, stage:iva, alive, 790 days	1160.2
TCGA-AF-2687-01A	57 years, male, white, stage:iiic, alive, 1427 days	1156.6
TCGA-AG-3732-01A	78 years, female, stage:i, alive, 1003 days	1152.9
TCGA-EI-6507-01A	60 years, male, white, stage:iia, alive, 607 days	1150.2
TCGA-F5-6813-01A	70 years, male, white, stage:iiic, dead, 598 days	1133.4
TCGA-G5-6572-01A	56 years, male, white, dead, 1432 days	1132.7
TCGA-AH-6643-01A	50 years, male, white, stage:iiic, dead, 1314 days	1129.4
TCGA-CI-6620-01A	41 years, female, white, stage:iva, alive, 1009 days	1092.5
TCGA-F5-6864-01A	74 years, female, white, stage:iiib, alive, 379 days	1081.9
TCGA-F5-6861-01A	60 years, female, white, stage:iia, alive, 1160 days	1080.9
TCGA-AG-A032-01A	68 years, male, stage:iiib, alive, 1157 days	1072.6
TCGA-F5-6465-01A	64 years, female, white, stage:iia, alive, 1506 days	1068.0
TCGA-AG-A036-01A	71 years, male, stage:iii, alive, 3562 days	1057.1
TCGA-AG-3599-01A	70 years, male, stage:i, alive, 366 days	1055.7
TCGA-EI-7004-01A	37 years, female, white, alive, 257 days	1054.7
TCGA-AH-6903-01A	46 years, male, white, stage:iiib, alive, 592 days	1049.4
TCGA-CI-6622-01A	74 years, male, white, stage:iib, alive, 1362 days	1043.2
TCGA-EI-6514-01A	59 years, female, white, stage:iia, alive, 496 days	1043.0
TCGA-AG-A00H-01A	75 years, male, stage:iia, alive, 790 days	1040.7
TCGA-AF-3400-01A	54 years, male, white, stage:iia, alive, 1049 days	1037.9
TCGA-AF-A56K-01A	56 years, male, black or african american, stage:iia, alive, 2635 days	1036.4
TCGA-AG-3909-01A	69 years, female, stage:iiib, alive, 608 days	1007.2
TCGA-AG-3890-01A	62 years, male, stage:i, alive, 518 days	986.5
TCGA-CL-4957-01A	79 years, female, dead, 425 days	981.8
TCGA-AG-3593-01A	72 years, female, stage:iia, alive, 1035 days	980.3
TCGA-AF-2690-01A	77 years, female, white, stage:iiic, dead, 524 days	968.0
TCGA-EI-6884-01A	71 years, male, white, stage:iiia, alive, 328 days	961.0
TCGA-EI-6513-01A	59 years, male, white, stage:iiib, alive, 497 days	946.7
TCGA-F5-6811-01A	72 years, female, white, stage:iia, alive, 979 days	946.2
TCGA-AG-3742-01A	85 years, female, stage:i, alive, 30 days	937.3
TCGA-AF-A56N-01A	47 years, female, black or african american, stage:iia, alive, 360 days	925.8
TCGA-AG-3594-01A	77 years, male, stage:iia, dead, 61 days	921.3
TCGA-EI-6510-01A	77 years, female, white, alive, 556 days	918.2
TCGA-DC-6683-01A	43 years, male, white, stage:iiib, alive, 762 days	917.4
TCGA-G5-6235-01A	72 years, male, white, stage:iiib, alive, 1696 days	916.5
TCGA-DC-6157-01A	48 years, male, black or african american, stage:i, alive, 1581 days	916.3
TCGA-DC-6160-01A	68 years, male, white, stage:i, alive, 1339 days	915.8
TCGA-EF-5831-01A	72 years, male, white, stage:iia, alive, 127 days	910.5
TCGA-AG-3898-01A	61 years, male, stage:iia, alive, 1461 days	898.5
TCGA-AG-A008-01A	50 years, female, stage:i, alive, 424 days	889.1
TCGA-EI-6512-01A	64 years, female, white, stage:iiib, alive, 538 days	881.0
TCGA-AG-A026-01A	66 years, male, stage:ii, dead, 59 days	880.2
TCGA-AH-6897-01A	48 years, male, white, stage:i, alive, 804 days	849.7
TCGA-AG-4008-01A	63 years, male, stage:iia, alive, 518 days	847.4
TCGA-CL-5917-01A	71 years, female, white, stage:iiic, alive, 2376 days	841.7
TCGA-DY-A1DF-01A	73 years, female, white, stage:iiic, dead, 734 days	838.1
TCGA-AG-3893-01A	74 years, male, stage:iiib, alive, 1065 days	834.3
TCGA-EI-6506-01A	78 years, female, white, stage:iia, alive, 625 days	823.1
TCGA-AG-3578-01A	76 years, female, stage:iia, alive, 974 days	822.2
TCGA-AG-A02N-01A	67 years, male, stage:ii, alive, 1885 days	816.5
TCGA-AG-3731-01A	65 years, male, stage:iv, alive, 1126 days	815.3
TCGA-DC-6156-01A	62 years, male, white, stage:iva, alive, 943 days	810.7
TCGA-F5-6812-01A	67 years, male, white, stage:iia, alive, 1110 days	803.9
TCGA-EI-6885-01A	57 years, female, white, stage:iv, alive, 415 days	785.0
TCGA-EI-6883-01A	63 years, male, white, stage:iic, alive, 350 days	762.7
TCGA-AF-6655-01A	66 years, male, white, stage:iiia, alive, 609 days	746.0
TCGA-AG-3901-01A	67 years, female, stage:iiib, alive, 761 days	726.1
TCGA-AG-A020-01A	57 years, female, stage:iii, alive, 31 days	714.1
TCGA-AG-A014-01A	86 years, male, stage:i, alive, 485 days	708.2
TCGA-F5-6702-01A	71 years, male, white, stage:iva, alive, 869 days	702.5
TCGA-AG-4001-01A	74 years, female, stage:iia, alive, 1096 days	699.7
TCGA-AG-A01J-01A	59 years, female, stage:iia, alive, 31 days	682.6
TCGA-F5-6464-01A	77 years, female, white, stage:iiic, dead, 303 days	578.5
TCGA-DC-6158-01A	70 years, male, white, stage:i, dead, 334 days	575.2
TCGA-AH-6547-01A	79 years, female, white, dead, 76 days	572.9
TCGA-AG-4021-01A	84 years, female, stage:iv, dead, 121 days	550.3
TCGA-AG-3584-01A	60 years, male, stage:iv, dead, 730 days	548.1
TCGA-DT-5265-01A	51 years, male, asian, stage:ii, alive, 384 days	547.1
TCGA-AF-2692-01A	54 years, female, white, stage:iia, alive, 412 days	545.0
TCGA-EI-6508-01A	48 years, female, white, stage:iiib, alive, 636 days	527.3
TCGA-EI-6511-01A	52 years, male, white, stage:iiib, alive, 482 days	490.0
TCGA-EI-6882-01A	59 years, male, white, stage:iia, alive, 262 days	489.9
TCGA-AG-A011-01A	80 years, male, stage:iia, alive, 1126 days	446.7
TCGA-CI-6624-01C	53 years, female, white, stage:i, alive, 1466 days	444.2
TCGA-AG-A002-01A	35 years, male, stage:i, alive, 638 days	372.7
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