Female fertility relies on the ovarian follicles that form during fetal development. Some medical treatments, such as chemo- or radiotherapy, are toxic to follicles and therefore ovarian tissue cryopreservation is used as a standard method for fertility preservation. This method is used for both adults and prepubertal individuals, even if its efficiency for tissue collected before puberty is not well documented...Read more

In a study published in the Journal of the Endocrine Society, transcriptomics analysis and radiological evaluation was used to explore the differences between invasive and noninvasive pituitary neuroendocrine tumors (PitNETs) with respect to parasellar growth, bone invasiveness and vascularization...Read more

In a study published in Nature Communications, the expression of all human protein-coding genes in more than 1,000 human cell lines representing 27 cancer types was investigated using genome-wide transcriptomics analysis...Read more

Pyruvate kinase muscle type (PKM) is a key enzyme in glycolysis and is a mediator of the Warburg effect in tumors. The association of PKM with survival of cancer patients is controversial. This study investigated the associations of the alternatively spliced transcripts of PKM with cancer patients' survival outcomes and explained the conflicts in previous studies. The article has recently been published in the journal Cancers...Read more

The article "A genome-wide transcriptomic analysis of protein-coding genes in human blood cells" is published in the journal Science on December 19...Read more