Expression of MT-CYB in colorectal cancer

RECTUM ADENOCARCINOMA (READ) - Interactive survival scatter plotⁱ

The Survival Scatter plot shows the clinical status (i.e. dead or alive) for all individuals in the patient cohort, based on the same data that underlies the corresponding Kaplan-Meier plots. Patients that are alive at last time for follow-up are shown in blue and patients who have died during the study are shown in red.

The x-axis shows the expression levels (FPKM) of the investigated gene in the tumor tissue at the time of diagnosis. The y-axis shows the follow-up time after diagnosis (years). Both axes are complimented with kernel density curves demonstrating the data density over the axes. The top density plot shows the expression levels (FPKM) distribution among dead (red) and alive patients (blue). The right density plot shows the data density of the survived years of dead patients with high and low expression levels respectively, stratified using the cutoff indicated by the vertical dashed line through the Survival Scatter plot. This cutoff is automatically defined based on the FPKM cutoff that minimizes the p-score. The cutoff can be changed by dragging the vertical line or by entering a cutoff value in the square labeled "Current cut-off".

Under the Survival Scatter plot the p-score landscape (black curve; left axis) is shown together with dead median separation (red curve; right axis). Dead median separation is the difference in median mRNA expression between patients who have died with high and low expression, respectively. It is calculated as follows: median FPKM expression of dead patients with high expression - median FPKM expression of dead patients with low expression. This is intended to aid the user in visually exploring custom cutoffs and the associated p-scores and dead median separation.

Individual patient data is displayed and can be filtered by clicking on one or more of the category buttons on the top of the page. Categories describing expression level and patient information include: high, low, alive, dead, female, male and tumor stages. The scale of the x-axis can be toggled between linear and log-scale by clicking on the "x log" button. Mouse-over function shows TCGA ID, patient information and mRNA expression (FPKM) for each patient.

& Survival analysisⁱ

Stage:

Survival analysis

Current cut offⁱ:
Best expression cut offⁱ: 5388.35
Median expressionⁱ: N/A
Median follow up timeⁱ: N/A
P scoreⁱ N/A
5-year survival highⁱ N/A
5-year survival lowⁱ N/A

TCGA RNA samplesⁱ

Average FPKM

4740.5

Number of samples

159

Samples

Sample	Description	FPKM
TCGA-DY-A1DF-01A	73 years, female, white, stage:iiic, dead, 734 days	27439.7
TCGA-CL-5918-01A	90 years, female, white, stage:iia, alive, 218 days	17204.0
TCGA-DY-A1H8-01A	77 years, female, white, stage:iiia, dead, 992 days	16396.3
TCGA-AG-A032-01A	68 years, male, stage:iiib, alive, 1157 days	13598.9
TCGA-AG-A00H-01A	75 years, male, stage:iia, alive, 790 days	13573.1
TCGA-F5-6812-01A	67 years, male, white, stage:iia, alive, 1110 days	12244.9
TCGA-AG-A02N-01A	67 years, male, stage:ii, alive, 1885 days	11995.3
TCGA-AG-A026-01A	66 years, male, stage:ii, dead, 59 days	11677.3
TCGA-BM-6198-01A	73 years, male, white, stage:iiib, alive, 646 days	11353.7
TCGA-AF-A56K-01A	56 years, male, black or african american, stage:iia, alive, 2635 days	10596.3
TCGA-DY-A1DD-01A	77 years, female, white, stage:iiib, dead, 1741 days	10575.7
TCGA-AG-A01J-01A	59 years, female, stage:iia, alive, 31 days	10435.0
TCGA-DY-A1DC-01A	72 years, female, white, stage:iia, dead, 1258 days	10120.2
TCGA-CI-6624-01C	53 years, female, white, stage:i, alive, 1466 days	9760.4
TCGA-AG-3890-01A	62 years, male, stage:i, alive, 518 days	9632.3
TCGA-AG-A015-01A	64 years, female, stage:i, alive, 1096 days	9388.0
TCGA-G5-6641-01A	67 years, male, white, stage:iiia, alive, 804 days	9174.7
TCGA-AG-A036-01A	71 years, male, stage:iii, alive, 3562 days	9132.7
TCGA-F5-6571-01A	62 years, female, white, stage:iia, alive, 1288 days	8562.4
TCGA-G5-6572-01A	56 years, male, white, dead, 1432 days	8261.5
TCGA-AG-3732-01A	78 years, female, stage:i, alive, 1003 days	8219.7
TCGA-DY-A1DG-01A	75 years, male, white, stage:iva, dead, 1566 days	7964.6
TCGA-AG-A011-01A	80 years, male, stage:iia, alive, 1126 days	7950.2
TCGA-AG-A025-01A	62 years, female, stage:i, alive, 1520 days	7901.8
TCGA-AG-3878-01A	64 years, male, stage:i, alive, 30 days	7877.2
TCGA-F5-6813-01A	70 years, male, white, stage:iiic, dead, 598 days	7530.0
TCGA-AG-3578-01A	76 years, female, stage:iia, alive, 974 days	7522.2
TCGA-EI-6514-01A	59 years, female, white, stage:iia, alive, 496 days	7415.7
TCGA-AG-A014-01A	86 years, male, stage:i, alive, 485 days	7291.1
TCGA-EI-6509-01A	53 years, male, white, stage:iiic, alive, 517 days	7240.7
TCGA-AG-3893-01A	74 years, male, stage:iiib, alive, 1065 days	7198.7
TCGA-AG-3882-01A	66 years, female, stage:i, alive, 608 days	7189.0
TCGA-AF-6672-01A	43 years, male, white, stage:iv, alive, 748 days	7055.2
TCGA-AG-A023-01A	62 years, female, stage:iv, dead, 1581 days	6931.0
TCGA-AG-3593-01A	72 years, female, stage:iia, alive, 1035 days	6683.9
TCGA-AH-6544-01A	60 years, male, white, alive, 1173 days	6667.3
TCGA-AG-A00Y-01A	68 years, male, stage:iia, alive, 700 days	6519.0
TCGA-AG-3583-01A	66 years, male, stage:iv, dead, 610 days	6274.2
TCGA-AG-A002-01A	35 years, male, stage:i, alive, 638 days	6073.1
TCGA-AG-A02G-01A	66 years, male, stage:iv, dead, 1185 days	6062.4
TCGA-AG-3612-01A	55 years, female, stage:iiib, alive, 608 days	5956.9
TCGA-AG-A01N-01A	68 years, female, stage:iv, alive, 943 days	5948.7
TCGA-AG-3883-01A	69 years, male, stage:i, alive, 31 days	5733.2
TCGA-AF-2692-01A	54 years, female, white, stage:iia, alive, 412 days	5649.2
TCGA-AH-6643-01A	50 years, male, white, stage:iiic, dead, 1314 days	5645.6
TCGA-AG-3580-01A	67 years, male, stage:i, alive, 244 days	5622.0
TCGA-AG-3742-01A	85 years, female, stage:i, alive, 30 days	5579.0
TCGA-AH-6547-01A	79 years, female, white, dead, 76 days	5461.1
TCGA-AG-3725-01A	90 years, female, stage:iii, alive, 638 days	5315.6
TCGA-G5-6235-01A	72 years, male, white, stage:iiib, alive, 1696 days	5294.5
TCGA-AF-A56L-01A	48 years, female, black or african american, stage:iiic, alive, 2007 days	5290.5
TCGA-EI-6510-01A	77 years, female, white, alive, 556 days	5234.0
TCGA-AG-3898-01A	61 years, male, stage:iia, alive, 1461 days	5076.9
TCGA-AH-6644-01A	73 years, male, white, alive, 838 days	4917.2
TCGA-CI-6619-01B	41 years, male, white, stage:iv, alive, 184 days	4850.9
TCGA-EI-6881-01A	60 years, male, white, stage:iiia, alive, 499 days	4780.9
TCGA-AG-A00C-01A	49 years, female, stage:iiib, alive, 183 days	4540.5
TCGA-AG-3726-01A	63 years, female, stage:i, alive, 243 days	4515.0
TCGA-AG-A008-01A	50 years, female, stage:i, alive, 424 days	4348.0
TCGA-AH-6903-01A	46 years, male, white, stage:iiib, alive, 592 days	4329.8
TCGA-AG-3600-01A	62 years, male, stage:iiic, alive, 184 days	4315.9
TCGA-EF-5831-01A	72 years, male, white, stage:iia, alive, 127 days	4252.1
TCGA-AF-2691-01A	48 years, female, white, stage:i, alive, 1309 days	4214.6
TCGA-DC-6157-01A	48 years, male, black or african american, stage:i, alive, 1581 days	4176.0
TCGA-AG-A020-01A	57 years, female, stage:iii, alive, 31 days	4143.6
TCGA-AG-4001-01A	74 years, female, stage:iia, alive, 1096 days	3960.7
TCGA-AG-3901-01A	67 years, female, stage:iiib, alive, 761 days	3957.3
TCGA-DC-6682-01A	57 years, male, white, stage:iia, alive, 762 days	3938.0
TCGA-CI-6623-01B	44 years, male, white, stage:i, alive, 1443 days	3918.6
TCGA-AG-3999-01A	61 years, female, stage:iiic, alive, 853 days	3916.9
TCGA-CI-6621-01A	63 years, male, white, stage:iiib, alive, 419 days	3899.0
TCGA-AG-3581-01A	63 years, male, stage:i, alive, 215 days	3886.9
TCGA-CL-4957-01A	79 years, female, dead, 425 days	3872.3
TCGA-AG-3584-01A	60 years, male, stage:iv, dead, 730 days	3851.2
TCGA-F5-6811-01A	72 years, female, white, stage:iia, alive, 979 days	3799.3
TCGA-CL-5917-01A	71 years, female, white, stage:iiic, alive, 2376 days	3792.4
TCGA-AG-3885-01A	71 years, female, stage:iiib, alive, 546 days	3663.6
TCGA-CI-6620-01A	41 years, female, white, stage:iva, alive, 1009 days	3633.3
TCGA-AG-3887-01A	68 years, male, stage:iia, alive, 1124 days	3620.1
TCGA-AF-A56N-01A	47 years, female, black or african american, stage:iia, alive, 360 days	3552.2
TCGA-AG-3574-01A	89 years, female, stage:ii, dead, 1096 days	3509.6
TCGA-AG-4022-01A	59 years, female, stage:ii, alive, 1400 days	3508.0
TCGA-AG-3592-01A	68 years, male, stage:iia, alive, 1035 days	3495.2
TCGA-AG-3909-01A	69 years, female, stage:iiib, alive, 608 days	3494.3
TCGA-AG-4005-01A	64 years, male, stage:iv, alive, 427 days	3451.0
TCGA-AG-3594-01A	77 years, male, stage:iia, dead, 61 days	3447.1
TCGA-F5-6465-01A	64 years, female, white, stage:iia, alive, 1506 days	3443.7
TCGA-DT-5265-01A	51 years, male, asian, stage:ii, alive, 384 days	3414.4
TCGA-AF-3911-01A	48 years, male, white, stage:iiic, alive, 1148 days	3352.9
TCGA-F5-6702-01A	71 years, male, white, stage:iva, alive, 869 days	3308.1
TCGA-AG-3611-01A	72 years, male, stage:iia, alive, 424 days	3295.7
TCGA-EI-6511-01A	52 years, male, white, stage:iiib, alive, 482 days	3291.2
TCGA-AF-2693-01A	75 years, male, white, stage:i, alive, 1155 days	3283.3
TCGA-AG-A016-01A	55 years, male, stage:iv, alive, 276 days	3218.5
TCGA-AF-2687-01A	57 years, male, white, stage:iiic, alive, 1427 days	3195.2
TCGA-AG-A02X-01A	77 years, male, stage:i, alive, 1247 days	3183.3
TCGA-EI-6508-01A	48 years, female, white, stage:iiib, alive, 636 days	3179.1
TCGA-EF-5830-01A	54 years, male, white, stage:iib, alive, 106 days	3144.4
TCGA-AG-3896-01A	85 years, female, stage:i, alive, 31 days	3041.2
TCGA-AG-3582-01A	75 years, male, stage:iv, dead, 1096 days	3022.8
TCGA-AF-2690-01A	77 years, female, white, stage:iiic, dead, 524 days	2985.5
TCGA-DY-A1DE-01A	56 years, female, white, stage:iia, alive, 3932 days	2980.8
TCGA-AF-3913-01A	60 years, male, black or african american, stage:iv, dead, 316 days	2957.3
TCGA-EI-6506-01A	78 years, female, white, stage:iia, alive, 625 days	2933.3
TCGA-EI-6512-01A	64 years, female, white, stage:iiib, alive, 538 days	2927.3
TCGA-DC-6683-01A	43 years, male, white, stage:iiib, alive, 762 days	2912.4
TCGA-DY-A0XA-01A	57 years, female, white, stage:iia, alive, 3846 days	2891.3
TCGA-CI-6622-01A	74 years, male, white, stage:iib, alive, 1362 days	2854.9
TCGA-AF-4110-01A	77 years, male, white, stage:iva, alive, 912 days	2837.8
TCGA-AF-3400-01A	54 years, male, white, stage:iia, alive, 1049 days	2834.2
TCGA-F5-6464-01A	77 years, female, white, stage:iiic, dead, 303 days	2806.7
TCGA-AF-6136-01A	72 years, female, white, stage:iiib, alive, 741 days	2770.3
TCGA-F5-6864-01A	74 years, female, white, stage:iiib, alive, 379 days	2767.2
TCGA-AG-4008-01A	63 years, male, stage:iia, alive, 518 days	2747.7
TCGA-EI-6513-01A	59 years, male, white, stage:iiib, alive, 497 days	2722.6
TCGA-AG-3586-01A	72 years, female, stage:iii, alive, 31 days	2639.3
TCGA-G5-6233-01A	74 years, male, white, dead, 556 days	2627.2
TCGA-AG-3727-01A	78 years, female, stage:iii, alive, 30 days	2610.6
TCGA-AG-3605-01A	85 years, female, stage:iv, alive, 30 days	2553.4
TCGA-AG-3608-01A	79 years, female, stage:iia, alive, 485 days	2550.8
TCGA-AG-3591-01A	66 years, female, stage:iia, alive, 1035 days	2491.5
TCGA-DC-6160-01A	68 years, male, white, stage:i, alive, 1339 days	2458.9
TCGA-AG-3881-01A	83 years, female, stage:iia, alive, 579 days	2397.8
TCGA-AG-3587-01A	65 years, male, stage:i, alive, 1400 days	2372.6
TCGA-AG-3731-01A	65 years, male, stage:iv, alive, 1126 days	2310.0
TCGA-AG-3894-01A	65 years, male, stage:iia, alive, 426 days	2261.6
TCGA-AG-4007-01A	87 years, male, stage:iv, alive, 31 days	2243.2
TCGA-F5-6861-01A	60 years, female, white, stage:iia, alive, 1160 days	2205.0
TCGA-DC-6156-01A	62 years, male, white, stage:iva, alive, 943 days	2193.6
TCGA-AG-3902-01A	61 years, male, stage:iia, alive, 974 days	2184.9
TCGA-AG-3892-01A	57 years, female, stage:i, alive, 396 days	2157.7
TCGA-DC-6681-01A	70 years, female, white, stage:iva, alive, 790 days	2140.4
TCGA-AF-6655-01A	66 years, male, white, stage:iiia, alive, 609 days	2079.1
TCGA-AG-3728-01A	73 years, male, stage:iiib, alive, 912 days	2063.5
TCGA-AG-3599-01A	70 years, male, stage:i, alive, 366 days	2055.9
TCGA-AG-4021-01A	84 years, female, stage:iv, dead, 121 days	1986.9
TCGA-DC-6158-01A	70 years, male, white, stage:i, dead, 334 days	1920.8
TCGA-EI-6883-01A	63 years, male, white, stage:iic, alive, 350 days	1885.9
TCGA-DC-4749-01A	57 years, male, white, stage:i, alive, 762 days	1857.3
TCGA-AH-6549-01A	66 years, male, white, alive, 532 days	1847.5
TCGA-AG-3598-01A	69 years, male, stage:iia, alive, 1522 days	1799.9
TCGA-F5-6814-01A	57 years, male, white, stage:iia, alive, 1131 days	1646.6
TCGA-AG-3609-01A	65 years, female, stage:iiic, alive, 608 days	1632.4
TCGA-EI-7002-01A	58 years, male, white, stage:iv, alive, 364 days	1549.9
TCGA-AF-5654-01A	73 years, female, white, stage:i, dead, 512 days	1503.3
TCGA-DC-6154-01A	57 years, female, white, stage:iva, alive, 365 days	1466.3
TCGA-EI-6884-01A	71 years, male, white, stage:iiia, alive, 328 days	1451.1
TCGA-F5-6863-01A	71 years, female, white, stage:iiib, dead, 361 days	1162.9
TCGA-EI-6917-01A	33 years, male, white, stage:iiia, alive, 531 days	1098.8
TCGA-EI-6882-01A	59 years, male, white, stage:iia, alive, 262 days	1094.2
TCGA-DC-4745-01A	49 years, female, white, stage:iiib, alive, 639 days	1010.9
TCGA-EI-6885-01A	57 years, female, white, stage:iv, alive, 415 days	982.2
TCGA-EI-6507-01A	60 years, male, white, stage:iia, alive, 607 days	968.7
TCGA-AG-3575-01A	51 years, male, stage:ii, alive, 365 days	895.7
TCGA-DC-6155-01A	31 years, female, white, stage:iiia, alive, 425 days	708.6
TCGA-DC-5869-01A	62 years, female, black or african american, stage:iiib, alive, 943 days	698.3
TCGA-EI-7004-01A	37 years, female, white, alive, 257 days	617.9
TCGA-AH-6897-01A	48 years, male, white, stage:i, alive, 804 days	507.3
TCGA-DC-5337-01A	69 years, male, white, stage:i, alive, 792 days	500.1
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