Expression of MT-CO1 in pancreatic cancer

PANCREATIC CANCER - Interactive survival scatter plotⁱ

The Survival Scatter plot shows the clinical status (i.e. dead or alive) for all individuals in the patient cohort, based on the same data that underlies the corresponding Kaplan-Meier plots. Patients that are alive at last time for follow-up are shown in blue and patients who have died during the study are shown in red.

The x-axis shows the expression levels (FPKM) of the investigated gene in the tumor tissue at the time of diagnosis. The y-axis shows the follow-up time after diagnosis (years). Both axes are complimented with kernel density curves demonstrating the data density over the axes. The top density plot shows the expression levels (FPKM) distribution among dead (red) and alive patients (blue). The right density plot shows the data density of the survived years of dead patients with high and low expression levels respectively, stratified using the cutoff indicated by the vertical dashed line through the Survival Scatter plot. This cutoff is automatically defined based on the FPKM cutoff that minimizes the p-score. The cutoff can be changed by dragging the vertical line or by entering a cutoff value in the square labeled "Current cut-off".

Under the Survival Scatter plot the p-score landscape (black curve; left axis) is shown together with dead median separation (red curve; right axis). Dead median separation is the difference in median mRNA expression between patients who have died with high and low expression, respectively. It is calculated as follows: median FPKM expression of dead patients with high expression - median FPKM expression of dead patients with low expression. This is intended to aid the user in visually exploring custom cutoffs and the associated p-scores and dead median separation.

Individual patient data is displayed and can be filtered by clicking on one or more of the category buttons on the top of the page. Categories describing expression level and patient information include: high, low, alive, dead, female, male and tumor stages. The scale of the x-axis can be toggled between linear and log-scale by clicking on the "x log" button. Mouse-over function shows TCGA ID, patient information and mRNA expression (FPKM) for each patient.

& Survival analysisⁱ

MT-CO1 is not prognostic in pancreatic cancer

Stage:

Survival analysis

Current cut offⁱ:
Best expression cut offⁱ: 5219.55
Median expressionⁱ: N/A
Median follow up timeⁱ: N/A
P scoreⁱ N/A
5-year survival highⁱ N/A
5-year survival lowⁱ N/A

TCGA RNA samplesⁱ

Average FPKM

7760.8

Number of samples

176

Samples

Sample	Description	FPKM
TCGA-FB-AAPY-01A	71 years, male, white, stage:iib, dead, 1059 days	22907.7
TCGA-H8-A6C1-01A	53 years, male, white, stage:iia, alive, 671 days	21343.0
TCGA-3A-A9IN-01A	62 years, female, white, stage:ib, alive, 2084 days	20534.1
TCGA-2J-AABK-01A	71 years, male, white, stage:iib, alive, 484 days	17766.7
TCGA-HV-A5A5-01A	61 years, female, asian, stage:iib, alive, 289 days	17215.8
TCGA-Q3-AA2A-01A	64 years, female, white, stage:ib, alive, 95 days	16036.1
TCGA-RB-A7B8-01A	81 years, female, white, stage:iib, dead, 466 days	15823.9
TCGA-F2-A44H-01A	65 years, male, white, stage:iia, alive, 586 days	15351.6
TCGA-FB-AAQ3-01A	65 years, female, white, stage:iib, dead, 31 days	15322.0
TCGA-HZ-A8P1-01A	81 years, male, white, stage:ib, alive, 7 days	15257.7
TCGA-HV-A5A6-01A	65 years, female, asian, stage:iib, dead, 2036 days	15236.7
TCGA-3A-A9IL-01A	39 years, female, white, stage:i, alive, 2741 days	14356.3
TCGA-LB-A7SX-01A	74 years, female, black or african american, stage:iib, dead, 393 days	13879.3
TCGA-FB-AAQ1-01A	49 years, male, white, stage:iib, dead, 123 days	13246.0
TCGA-2J-AABH-01A	61 years, male, white, stage:iia, alive, 1287 days	13066.1
TCGA-IB-A5SP-01A	77 years, male, white, stage:iia, alive, 482 days	12964.3
TCGA-FB-AAQ6-01A	85 years, male, white, stage:ia, dead, 244 days	12632.3
TCGA-2L-AAQJ-01A	49 years, female, white, stage:iii, dead, 394 days	12631.0
TCGA-IB-7649-01A	73 years, female, stage:iib, dead, 467 days	12569.9
TCGA-M8-A5N4-01A	48 years, female, stage:iia, alive, 584 days	12481.3
TCGA-HZ-A4BK-01A	72 years, male, white, stage:iib, alive, 657 days	12464.5
TCGA-HV-AA8V-01A	50 years, male, asian, stage:iib, alive, 920 days	12074.3
TCGA-HZ-A9TJ-01A	70 years, male, white, stage:iv, alive, 603 days	12023.9
TCGA-HZ-8638-01A	84 years, female, white, stage:ia, dead, 151 days	11732.3
TCGA-3A-A9I7-01A	45 years, male, black or african american, stage:iib, alive, 1323 days	11703.9
TCGA-IB-AAUO-01A	64 years, female, white, stage:iib, dead, 239 days	11676.0
TCGA-3A-A9IV-01A	59 years, female, white, stage:ib, alive, 1103 days	11654.9
TCGA-HV-A5A3-01A	50 years, male, asian, stage:iia, dead, 128 days	11596.4
TCGA-Q3-A5QY-01A	58 years, male, white, stage:iib, alive, 416 days	11518.1
TCGA-3A-A9IS-01A	67 years, male, white, stage:ib, alive, 998 days	11242.2
TCGA-F2-A44G-01A	79 years, female, white, stage:iib, dead, 233 days	11115.8
TCGA-2L-AAQM-01A	52 years, male, white, stage:iib, alive, 1383 days	10998.1
TCGA-US-A77E-01A	73 years, male, white, stage:iib, dead, 430 days	10783.9
TCGA-3A-A9I9-01A	67 years, male, white, stage:iia, dead, 634 days	10766.4
TCGA-FB-AAQ0-01A	68 years, male, white, stage:iia, dead, 473 days	10572.6
TCGA-3A-A9IO-01A	56 years, male, white, alive, 1942 days	10549.7
TCGA-HZ-8315-01A	54 years, female, white, stage:iia, dead, 299 days	10545.3
TCGA-HV-A5A4-01A	72 years, female, asian, stage:iia, alive, 232 days	10160.0
TCGA-2J-AABT-01A	72 years, female, white, stage:iib, alive, 319 days	9859.3
TCGA-FB-AAPQ-01A	65 years, male, white, stage:iib, dead, 1130 days	9751.2
TCGA-HZ-A49G-01A	58 years, female, white, stage:iib, alive, 660 days	9677.3
TCGA-XD-AAUI-01A	50 years, female, white, stage:iib, dead, 366 days	9598.2
TCGA-3E-AAAY-01A	67 years, male, white, stage:iib, alive, 2285 days	9597.2
TCGA-S4-A8RM-01A	67 years, male, white, stage:iib, alive, 737 days	9562.7
TCGA-S4-A8RP-01A	77 years, female, white, stage:iib, dead, 702 days	9379.4
TCGA-FB-A545-01A	72 years, female, white, stage:iib, dead, 732 days	9207.1
TCGA-FB-AAPU-01A	41 years, female, asian, stage:iia, dead, 381 days	9176.0
TCGA-2J-AABE-01A	73 years, male, white, stage:iia, alive, 676 days	8921.5
TCGA-HZ-8637-01A	76 years, female, white, stage:iib, dead, 517 days	8876.7
TCGA-IB-AAUQ-01A	50 years, male, white, stage:iib, dead, 183 days	8854.7
TCGA-US-A779-01A	54 years, female, white, stage:iib, dead, 511 days	8835.0
TCGA-H6-A45N-01A	88 years, female, white, stage:iib, dead, 421 days	8800.7
TCGA-HV-AA8X-01A	75 years, female, asian, stage:iib, dead, 532 days	8747.6
TCGA-HZ-A49H-01A	68 years, female, white, stage:iib, alive, 491 days	8704.1
TCGA-2L-AAQI-01A	66 years, male, white, stage:iib, dead, 103 days	8691.0
TCGA-FB-AAPZ-01A	54 years, male, white, stage:iib, alive, 716 days	8646.5
TCGA-HZ-8519-01A	73 years, male, white, stage:ia, alive, 454 days	8630.8
TCGA-FB-AAPP-01A	71 years, male, white, stage:iib, dead, 485 days	8618.5
TCGA-2J-AAB1-01A	65 years, male, white, stage:iib, dead, 66 days	8591.0
TCGA-L1-A7W4-01A	48 years, female, white, stage:iib, dead, 278 days	8569.8
TCGA-HZ-A77P-01A	77 years, male, white, stage:iib, alive, 330 days	8555.8
TCGA-3A-A9IH-01A	66 years, female, white, stage:ia, alive, 1021 days	8542.1
TCGA-2J-AABF-01A	73 years, male, white, stage:iib, dead, 691 days	8482.1
TCGA-FB-AAPS-01A	62 years, female, white, stage:iib, alive, 228 days	8341.2
TCGA-HZ-8317-01A	69 years, female, white, stage:iib, dead, 378 days	8306.5
TCGA-3A-A9IR-01A	64 years, female, white, stage:ib, alive, 1542 days	8236.4
TCGA-3A-A9J0-01A	75 years, male, white, stage:iib, alive, 743 days	8235.5
TCGA-FB-A4P5-01A	69 years, female, white, stage:iib, dead, 179 days	8184.2
TCGA-YH-A8SY-01A	73 years, female, white, alive, 388 days	8182.0
TCGA-3A-A9IX-01A	40 years, male, white, stage:ia, alive, 1037 days	8174.9
TCGA-US-A77G-01A	64 years, male, white, stage:iib, dead, 12 days	8161.0
TCGA-XD-AAUH-01A	57 years, female, white, stage:iib, alive, 395 days	8085.6
TCGA-IB-A5SO-01A	71 years, male, white, stage:iib, dead, 365 days	8066.3
TCGA-2J-AABA-01A	55 years, male, white, stage:iib, dead, 607 days	8021.4
TCGA-FB-A78T-01A	71 years, female, white, stage:iib, dead, 375 days	7955.7
TCGA-XN-A8T5-01A	53 years, female, white, stage:ib, alive, 720 days	7938.6
TCGA-2J-AABU-01A	56 years, male, white, stage:iib, dead, 277 days	7874.3
TCGA-IB-A6UF-01A	63 years, male, white, stage:iib, alive, 666 days	7843.4
TCGA-2J-AABO-01A	43 years, male, white, stage:iib, alive, 440 days	7835.5
TCGA-IB-7651-01A	64 years, female, white, stage:iib, dead, 603 days	7586.7
TCGA-2J-AABR-01A	60 years, female, white, stage:iia, alive, 438 days	7581.0
TCGA-XN-A8T3-01A	67 years, male, white, stage:ib, alive, 951 days	7417.0
TCGA-IB-A7M4-01A	81 years, male, white, stage:iib, alive, 483 days	7321.9
TCGA-3A-A9IB-01A	69 years, female, white, stage:iib, dead, 224 days	7319.6
TCGA-IB-AAUT-01A	65 years, male, white, stage:iib, alive, 287 days	7301.8
TCGA-FB-AAQ2-01A	81 years, female, white, stage:iib, dead, 153 days	7241.7
TCGA-IB-AAUR-01A	67 years, male, white, stage:iib, alive, 338 days	7129.8
TCGA-3A-A9I5-01A	58 years, male, white, alive, 1794 days	7065.6
TCGA-HZ-A77Q-01A	55 years, female, white, stage:iib, alive, 33 days	6999.6
TCGA-IB-AAUU-01A	35 years, male, white, stage:iib, alive, 245 days	6971.1
TCGA-2J-AAB4-01A	48 years, male, white, stage:iib, alive, 729 days	6922.3
TCGA-S4-A8RO-01A	75 years, female, white, stage:iib, alive, 525 days	6854.0
TCGA-FB-A4P6-01A	54 years, male, white, stage:iib, alive, 767 days	6826.1
TCGA-US-A776-01A	61 years, male, white, stage:iia, alive, 1216 days	6718.9
TCGA-IB-AAUW-01A	63 years, female, white, stage:iib, dead, 230 days	6694.8
TCGA-2L-AAQA-01A	76 years, male, white, stage:iib, dead, 143 days	6685.4
TCGA-2J-AABI-01A	55 years, female, white, stage:iia, alive, 969 days	6630.2
TCGA-FB-A7DR-01A	48 years, male, asian, stage:iia, dead, 353 days	6529.5
TCGA-IB-AAUN-01A	74 years, female, white, stage:ib, dead, 144 days	6512.4
TCGA-HZ-A4BH-01A	75 years, male, white, stage:iib, alive, 194 days	6436.6
TCGA-IB-8126-01A	80 years, female, white, stage:iii, alive, 462 days	6432.2
TCGA-3A-A9IJ-01A	65 years, male, white, stage:ib, alive, 1854 days	6359.4
TCGA-HZ-7289-01A	77 years, male, white, stage:iib, dead, 661 days	6338.4
TCGA-RL-AAAS-01A	60 years, female, white, stage:ib, alive, 9 days	6329.7
TCGA-XD-AAUG-01A	66 years, female, white, stage:iv, alive, 420 days	6309.6
TCGA-3A-A9IU-01A	65 years, male, white, stage:iib, dead, 458 days	6294.0
TCGA-F2-A8YN-01A	76 years, male, white, stage:iia, alive, 517 days	6294.0
TCGA-2L-AAQE-01A	56 years, male, white, stage:iib, dead, 684 days	6235.7
TCGA-IB-AAUS-01A	84 years, female, white, stage:iib, alive, 225 days	6232.6
TCGA-RB-AA9M-01A	43 years, male, white, stage:iib, alive, 286 days	6195.1
TCGA-HZ-A77O-01A	77 years, female, white, stage:iib, dead, 160 days	6129.2
TCGA-HZ-A49I-01A	77 years, male, white, stage:iib, dead, 308 days	6128.0
TCGA-IB-AAUM-01A	76 years, male, white, stage:iib, alive, 8 days	6088.0
TCGA-HZ-7924-01A	60 years, female, white, stage:iia, alive, 840 days	6070.0
TCGA-F2-A7TX-01A	77 years, male, white, stage:iib, dead, 95 days	6069.8
TCGA-IB-AAUP-01A	68 years, male, white, stage:iib, alive, 431 days	6048.2
TCGA-IB-AAUV-01A	49 years, male, white, stage:iib, alive, 404 days	6012.6
TCGA-PZ-A5RE-01A	44 years, female, white, stage:iib, dead, 470 days	5976.9
TCGA-Z5-AAPL-01A	74 years, female, white, stage:iia, alive, 467 days	5939.6
TCGA-IB-7645-01A	44 years, female, stage:iib, dead, 1502 days	5933.4
TCGA-IB-A6UG-01A	65 years, male, white, stage:iib, dead, 41 days	5903.7
TCGA-IB-7897-01A	54 years, female, white, stage:iib, dead, 486 days	5897.9
TCGA-US-A774-01A	76 years, female, white, stage:iib, dead, 695 days	5848.6
TCGA-IB-7644-01A	65 years, female, white, stage:iv, dead, 394 days	5837.9
TCGA-3E-AAAZ-01A	71 years, male, white, stage:iia, dead, 2182 days	5613.5
TCGA-IB-7885-01A	78 years, female, white, stage:iib, alive, 1257 days	5566.6
TCGA-IB-A5SQ-01A	56 years, female, white, stage:ib, dead, 219 days	5472.8
TCGA-IB-A5ST-01A	64 years, female, white, stage:iib, alive, 635 days	5462.7
TCGA-2L-AAQL-01A	82 years, male, white, stage:iib, dead, 292 days	5428.3
TCGA-XD-AAUL-01A	56 years, male, white, stage:iia, alive, 498 days	5354.9
TCGA-F2-6880-01A	70 years, male, white, stage:iib, alive, 289 days	5349.0
TCGA-HZ-7923-01A	65 years, male, white, stage:iia, alive, 314 days	5285.8
TCGA-3A-A9IZ-01A	47 years, male, white, stage:iib, dead, 308 days	5153.3
TCGA-HZ-8002-01A	61 years, male, white, stage:iib, dead, 366 days	5022.2
TCGA-LB-A9Q5-01A	63 years, female, white, stage:iib, dead, 313 days	4985.4
TCGA-IB-7646-01A	60 years, male, white, stage:iib, dead, 145 days	4938.6
TCGA-US-A77J-01A	81 years, female, white, stage:iib, dead, 568 days	4881.7
TCGA-HV-A7OL-01A	70 years, male, asian, stage:iia, alive, 252 days	4843.5
TCGA-IB-7652-01A	49 years, female, asian, stage:iib, alive, 1116 days	4821.5
TCGA-3A-A9IC-01A	61 years, female, white, stage:iib, dead, 738 days	4787.4
TCGA-HZ-7920-01A	71 years, male, white, stage:ib, dead, 236 days	4624.2
TCGA-IB-8127-01A	59 years, male, white, stage:iib, alive, 522 days	4366.3
TCGA-F2-7276-01A	64 years, male, white, stage:iib, dead, 216 days	4323.0
TCGA-YB-A89D-01A	59 years, male, white, stage:iib, alive, 350 days	4288.1
TCGA-2J-AAB9-01A	71 years, female, white, stage:iib, dead, 627 days	4253.9
TCGA-HZ-7926-01A	57 years, male, black or african american, stage:iib, dead, 518 days	4180.1
TCGA-YY-A8LH-01A	61 years, female, white, stage:iib, alive, 2016 days	4146.3
TCGA-HZ-8001-01A	69 years, male, white, stage:iii, alive, 706 days	4032.2
TCGA-HZ-7925-01A	66 years, male, white, stage:iib, dead, 614 days	3956.7
TCGA-IB-A7LX-01A	57 years, male, white, stage:iib, dead, 250 days	3914.0
TCGA-HZ-7919-01A	52 years, female, white, stage:iib, dead, 593 days	3863.2
TCGA-IB-A5SS-01A	64 years, female, white, stage:iib, dead, 460 days	3731.5
TCGA-IB-7889-01A	86 years, female, white, stage:iib, dead, 481 days	3727.0
TCGA-IB-7888-01A	66 years, female, black or african american, stage:iia, dead, 1332 days	3699.8
TCGA-H6-8124-01A	56 years, female, white, stage:iib, alive, 392 days	3697.3
TCGA-IB-7887-01A	62 years, female, white, stage:iib, dead, 110 days	3677.1
TCGA-IB-7654-01A	80 years, male, white, stage:iib, dead, 476 days	3668.6
TCGA-OE-A75W-01A	75 years, male, white, stage:iia, dead, 267 days	3640.9
TCGA-FB-A5VM-01A	74 years, male, white, stage:ib, dead, 498 days	3468.8
TCGA-IB-7891-01A	49 years, female, white, stage:iib, dead, 913 days	3399.2
TCGA-2J-AAB6-01A	75 years, male, white, stage:iia, dead, 293 days	3227.2
TCGA-HZ-8636-01A	58 years, female, white, stage:iv, dead, 545 days	3205.4
TCGA-IB-7890-01A	73 years, male, stage:ib, dead, 598 days	3051.9
TCGA-IB-7893-01A	64 years, male, white, stage:iia, dead, 117 days	2912.7
TCGA-HZ-8003-01A	65 years, female, white, stage:iib, dead, 596 days	2912.3
TCGA-LB-A8F3-01A	64 years, female, black or african american, stage:iia, alive, 379 days	2908.3
TCGA-HZ-7918-01A	72 years, male, white, stage:iib, alive, 969 days	2825.5
TCGA-2J-AABV-01A	74 years, male, white, stage:iib, dead, 652 days	2815.1
TCGA-F2-6879-01A	57 years, male, white, stage:iib, dead, 334 days	2738.2
TCGA-HZ-8005-01A	81 years, male, white, stage:iib, dead, 120 days	2714.4
TCGA-HV-A7OP-01A	72 years, male, asian, stage:iib, alive, 978 days	2672.7
TCGA-F2-7273-01A	54 years, male, black or african american, stage:iib, dead, 592 days	2421.0
TCGA-2J-AAB8-01A	71 years, male, white, stage:iib, alive, 80 days	2306.7
TCGA-HZ-7922-01A	61 years, female, white, stage:iib, alive, 4 days	2263.2
TCGA-2J-AABP-01A	58 years, female, white, stage:iib, alive, 463 days	1963.9
TCGA-IB-7886-01A	80 years, male, white, stage:iib, dead, 123 days	1571.1
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PANCREATIC CANCER - Protein expressionⁱ A mouse-over function shows sample information and annotation data. Click on an image to view it in a full screen mode. Samples can be filtered based on level of antibody staining by selecting one or several of the following categories: high, medium, low and not detected. The assay and annotation is described here. Note that samples used for immunohistochemistry by the Human Protein Atlas do not correspond to samples in the TCGA dataset.

Antibody stainingⁱ Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high. This score is based on the staining intensity and fraction of stained cells. Read more	Antibody HPA069328	Antibody CAB016241
Staining
High
Medium
Low
Not detected
Intensity
Strong
Moderate
Weak
Negative
Quantity
>75%
75%-25%
<25%
None
Location
Nuclear
Cytoplasmic/membranous
Cytoplasmic/membranous,nuclear
None
Click images for details