Expression of MT-CO1 in testis cancer - The Human Protein Atlas

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MT-CO1

SUMMARY

TISSUE

CELL TYPE

PATHOLOGY

BRAIN

BLOOD

CELL

TESTIS CANCER - Interactive survival scatter plotⁱ

The Survival Scatter plot shows the clinical status (i.e. dead or alive) for all individuals in the patient cohort, based on the same data that underlies the corresponding Kaplan-Meier plots. Patients that are alive at last time for follow-up are shown in blue and patients who have died during the study are shown in red.

The x-axis shows the expression levels (FPKM) of the investigated gene in the tumor tissue at the time of diagnosis. The y-axis shows the follow-up time after diagnosis (years). Both axes are complimented with kernel density curves demonstrating the data density over the axes. The top density plot shows the expression levels (FPKM) distribution among dead (red) and alive patients (blue). The right density plot shows the data density of the survived years of dead patients with high and low expression levels respectively, stratified using the cutoff indicated by the vertical dashed line through the Survival Scatter plot. This cutoff is automatically defined based on the FPKM cutoff that minimizes the p-score. The cutoff can be changed by dragging the vertical line or by entering a cutoff value in the square labeled "Current cut-off".

Under the Survival Scatter plot the p-score landscape (black curve; left axis) is shown together with dead median separation (red curve; right axis). Dead median separation is the difference in median mRNA expression between patients who have died with high and low expression, respectively. It is calculated as follows: median FPKM expression of dead patients with high expression - median FPKM expression of dead patients with low expression. This is intended to aid the user in visually exploring custom cutoffs and the associated p-scores and dead median separation.

Individual patient data is displayed and can be filtered by clicking on one or more of the category buttons on the top of the page. Categories describing expression level and patient information include: high, low, alive, dead, female, male and tumor stages. The scale of the x-axis can be toggled between linear and log-scale by clicking on the "x log" button. Mouse-over function shows TCGA ID, patient information and mRNA expression (FPKM) for each patient.

& Survival analysisⁱ

MT-CO1 is not prognostic in testis cancer

Stage:

Survival analysis

Current cut offⁱ:
Best expression cut offⁱ: 5568.46
Median expressionⁱ: N/A
Median follow up timeⁱ: N/A
P scoreⁱ N/A
5-year survival highⁱ N/A
5-year survival lowⁱ N/A

TCGA RNA samplesⁱ

Average FPKM

6467.1

Number of samples

134

Samples

Sample	Description	FPKM
TCGA-ZM-AA05-01A	36 years, male, white, stage:iic, alive, 1126 days	73874.7
TCGA-ZM-AA0F-01A	35 years, male, white, stage:ia, alive, 681 days	40515.8
TCGA-ZM-AA0H-01A	50 years, male, white, stage:is, alive, 1736 days	36307.4
TCGA-ZM-AA06-01A	45 years, male, white, stage:ib, alive, 1498 days	36280.0
TCGA-XE-AAOL-01A	38 years, male, black or african american, stage:i, alive, 13 days	34204.4
TCGA-ZM-AA0E-01A	39 years, male, white, stage:ia, alive, 811 days	31063.8
TCGA-ZM-AA0N-01A	44 years, male, white, stage:ib, alive, 634 days	23419.3
TCGA-XE-AAO6-01A	47 years, male, white, stage:ia, alive, 240 days	21993.6
TCGA-ZM-AA0B-01A	32 years, male, white, stage:ia, alive, 838 days	18648.0
TCGA-ZM-AA0D-01A	34 years, male, white, stage:ia, alive, 848 days	15129.9
TCGA-XE-AAO4-01A	40 years, male, white, stage:ia, alive, 367 days	12309.8
TCGA-2G-AAGG-01A	20 years, male, white, stage:iiic, alive, 2611 days	11746.1
TCGA-YU-A90S-01A	26 years, male, white, stage:ia, alive, 971 days	10558.1
TCGA-W4-A7U4-01A	23 years, male, white, alive, 738 days	8458.8
TCGA-2G-AAG6-01A	24 years, male, white, stage:is, alive, 2231 days	8017.3
TCGA-YU-A94I-01A	66 years, male, stage:ia, alive, 536 days	7696.3
TCGA-YU-A90Y-01A	23 years, male, black or african american, stage:iiic, dead, 17 days	7689.4
TCGA-XE-AAOJ-01A	24 years, male, white, stage:is, alive, 1550 days	7608.3
TCGA-WZ-A8D5-01A	38 years, male, white, alive, 774 days	7156.4
TCGA-YU-A90P-01A	25 years, male, white, stage:ia, alive, 2069 days	7017.4
TCGA-2G-AAGV-01A	23 years, male, white, alive, 4527 days	6506.7
TCGA-2G-AAG5-01A	36 years, male, white, stage:is, alive, 2299 days	6482.8
TCGA-2G-AAGE-01A	21 years, male, white, stage:is, alive, 2478 days	6187.9
TCGA-XY-A89B-01A	35 years, male, white, stage:ia, alive, 471 days	6142.7
TCGA-2G-AAKL-01A	26 years, male, white, stage:ii, alive, 7023 days	6093.2
TCGA-4K-AA1I-01A	26 years, male, white, stage:ia, alive, 3 days	6028.1
TCGA-S6-A8JY-01A	27 years, male, white, stage:is, alive, 278 days	6008.5
TCGA-2G-AAG0-01A	23 years, male, white, stage:is, alive, 1529 days	5934.3
TCGA-VF-A8AB-01A	31 years, male, black or african american, stage:ia, alive, 760 days	5757.8
TCGA-VF-A8AE-01A	39 years, male, white, stage:ia, alive, 727 days	5705.9
TCGA-2G-AAGA-01A	38 years, male, white, stage:iia, alive, 2439 days	5665.1
TCGA-XE-A8H4-01A	23 years, male, white, stage:ia, alive, 559 days	5603.7
TCGA-XE-AAOB-01A	27 years, male, white, stage:is, dead, 513 days	5598.1
TCGA-2G-AAKM-01A	14 years, male, white, stage:ii, dead, 6972 days	5577.8
TCGA-2G-AAH2-01A	20 years, male, white, stage:is, alive, 6060 days	5559.1
TCGA-XE-AAOC-01A	31 years, male, white, stage:ia, alive, 270 days	5510.1
TCGA-2G-AAFY-01A	24 years, male, white, stage:iia, alive, 1099 days	5482.4
TCGA-VF-A8AD-01A	36 years, male, white, stage:ib, alive, 1006 days	5423.9
TCGA-YU-AA4L-01A	27 years, male, black or african american, stage:iiic, alive, 1573 days	5379.1
TCGA-2G-AAGY-01A	28 years, male, white, stage:is, alive, 5329 days	5314.5
TCGA-XE-AAOD-01A	39 years, male, white, stage:ib, alive, 2058 days	5308.4
TCGA-2G-AAG3-01A	53 years, male, white, stage:is, alive, 1593 days	5283.4
TCGA-2G-AAL7-01A	32 years, male, white, stage:is, alive, 3991 days	5197.1
TCGA-VF-A8A8-01A	18 years, male, white, stage:ia, alive, 1131 days	5043.8
TCGA-2G-AAG8-01A	21 years, male, white, stage:ib, alive, 2289 days	5036.5
TCGA-2G-AAFL-01A	35 years, male, white, stage:ib, alive, 750 days	4985.1
TCGA-WZ-A7V4-01A	28 years, male, white, stage:i, alive, 894 days	4982.8
TCGA-2G-AAFM-01A	31 years, male, white, stage:iia, alive, 503 days	4979.6
TCGA-XE-AANJ-01A	39 years, male, white, stage:is, alive, 2007 days	4898.0
TCGA-4K-AAAL-01A	31 years, male, white, stage:is, alive, 483 days	4872.6
TCGA-2G-AAFE-01A	37 years, male, white, stage:iia, alive, 4702 days	4858.1
TCGA-4K-AA1H-01A	26 years, male, white, stage:ia, alive, 518 days	4821.1
TCGA-SN-A84W-01A	30 years, male, white, stage:is, alive, 293 days	4793.5
TCGA-2G-AAGP-01A	33 years, male, white, stage:iia, alive, 4018 days	4767.0
TCGA-S6-A8JX-01A	27 years, male, white, stage:ib, alive, 552 days	4698.4
TCGA-2G-AAFJ-01A	23 years, male, asian, alive, 792 days	4623.0
TCGA-2G-AAG9-01A	25 years, male, white, stage:iiib, alive, 2234 days	4595.8
TCGA-VF-A8A9-01A	31 years, male, white, stage:ia, alive, 1119 days	4518.6
TCGA-2G-AAFH-01A	38 years, male, white, stage:iib, alive, 1375 days	4450.1
TCGA-2G-AAFN-01A	26 years, male, white, stage:iiib, alive, 773 days	4439.7
TCGA-2G-AAGZ-01A	27 years, male, white, stage:iiia, alive, 5233 days	4425.1
TCGA-2G-AAGF-01A	28 years, male, white, stage:is, alive, 2734 days	4422.4
TCGA-XE-A8H1-01A	24 years, male, white, stage:is, alive, 209 days	4408.4
TCGA-2G-AAGN-01A	41 years, male, white, stage:iiib, alive, 3656 days	4311.3
TCGA-2G-AALP-01A	43 years, male, white, stage:iiib, alive, 2645 days	4291.1
TCGA-2G-AAGO-01A	41 years, male, white, stage:is, alive, 4026 days	4275.4
TCGA-2G-AAFI-01A	41 years, male, white, stage:ib, alive, 675 days	4212.2
TCGA-2G-AAKG-01A	22 years, male, white, stage:i, alive, 6598 days	4196.9
TCGA-2G-AAFG-01A	30 years, male, white, stage:is, alive, 6183 days	4168.1
TCGA-2G-AAG7-01A	33 years, male, white, stage:is, alive, 2475 days	4157.5
TCGA-2G-AAGC-01A	28 years, male, white, stage:is, alive, 2585 days	4152.5
TCGA-X3-A8G4-01A	33 years, male, white, stage:is, alive, 856 days	4127.2
TCGA-2G-AAH0-01A	30 years, male, white, stage:is, alive, 5477 days	4019.7
TCGA-2G-AAKH-01A	19 years, male, white, stage:ii, alive, 6862 days	3956.1
TCGA-XY-A8S3-01B	24 years, male, white, stage:is, alive, 843 days	3928.0
TCGA-SN-A6IS-01A	26 years, male, white, stage:is, alive, 496 days	3917.2
TCGA-YU-A90W-01A	45 years, male, white, stage:ia, alive, 1113 days	3893.5
TCGA-XE-AANI-01A	37 years, male, white, stage:is, alive, 1041 days	3888.0
TCGA-2G-AAHA-01A	48 years, male, white, stage:ib, alive, 3349 days	3860.3
TCGA-2G-AAGI-01A	33 years, male, white, stage:is, alive, 3137 days	3854.3
TCGA-YU-A94D-01A	28 years, male, stage:iiib, alive, 2167 days	3726.9
TCGA-2G-AAF8-01A	33 years, male, white, stage:ia, alive, 3911 days	3711.1
TCGA-2G-AAGW-01A	38 years, male, white, stage:is, alive, 4899 days	3693.0
TCGA-SN-A84Y-01A	18 years, male, white, stage:is, alive, 524 days	3691.6
TCGA-YU-AA61-01A	29 years, male, white, stage:is, alive, 864 days	3668.3
TCGA-XE-A8H5-01A	29 years, male, stage:is, alive, 1217 days	3641.0
TCGA-2G-AAKD-01A	18 years, male, white, stage:iii, alive, 6340 days	3606.9
TCGA-2G-AAGS-01A	39 years, male, white, stage:iiib, alive, 4816 days	3606.5
TCGA-WZ-A7V3-01A	20 years, male, white, stage:i, alive, 753 days	3584.2
TCGA-W4-A7U3-01A	26 years, male, white, alive, 149 days	3571.0
TCGA-2G-AAGJ-01A	28 years, male, black or african american, stage:ia, alive, 2938 days	3503.1
TCGA-WZ-A7V5-01A	27 years, male, white, stage:i, alive, 1061 days	3422.9
TCGA-2G-AAFV-01A	31 years, male, white, stage:is, alive, 1389 days	3400.2
TCGA-YU-A90Q-01A	21 years, male, stage:ib, alive, 1964 days	3394.0
TCGA-XE-AAOF-01A	50 years, male, asian, stage:ia, alive, 1268 days	3329.6
TCGA-VF-A8AA-01A	51 years, male, white, stage:i, alive, 1146 days	3325.8
TCGA-2G-AAEX-01A	38 years, male, white, stage:is, alive, 1259 days	3310.2
TCGA-2G-AAGM-01A	51 years, male, white, stage:is, alive, 3891 days	3308.9
TCGA-2G-AAH4-01A	34 years, male, white, stage:ii, alive, 6210 days	3298.5
TCGA-2G-AAFO-01A	33 years, male, white, stage:iia, alive, 685 days	3229.8
TCGA-YU-A912-01A	34 years, male, black or african american, stage:iiic, alive, 866 days	3182.3
TCGA-2X-A9D5-01A	49 years, male, white, stage:i, alive, 435 days	3121.6
TCGA-2G-AAHC-01A	33 years, male, white, stage:is, alive, 5539 days	3025.2
TCGA-2G-AAH3-01A	20 years, male, white, stage:i, alive, 1822 days	3014.1
TCGA-2G-AAGX-01A	22 years, male, white, stage:ia, alive, 5514 days	2998.7
TCGA-2G-AAFZ-01A	32 years, male, white, stage:iii, alive, 1353 days	2932.6
TCGA-2G-AAHG-01A	25 years, male, white, stage:i, alive, 1819 days	2875.8
TCGA-2G-AAGT-01A	30 years, male, white, stage:is, alive, 4406 days	2831.0
TCGA-XE-A9SE-01A	35 years, male, white, stage:ia, alive, 708 days	2827.6
TCGA-XY-A8S2-01A	67 years, male, white, stage:i, alive, 672 days	2735.1
TCGA-W4-A7U2-01A	26 years, male, white, alive, 1263 days	2726.7
TCGA-2X-A9D6-01A	42 years, male, white, stage:i, alive, 607 days	2703.1
TCGA-SN-A84X-01A	21 years, male, white, stage:is, alive, 312 days	2642.9
TCGA-2G-AAF4-01A	30 years, male, white, stage:i, alive, 2315 days	2630.4
TCGA-XE-AAO3-01A	33 years, male, asian, stage:i, alive, 2857 days	2604.2
TCGA-XE-AANR-01A	24 years, male, white, stage:i, alive, 14 days	2570.8
TCGA-S6-A8JW-01A	37 years, male, white, stage:is, alive, 698 days	2560.6
TCGA-2G-AAHN-01A	32 years, male, white, stage:i, alive, 6445 days	2553.1
TCGA-SB-A6J6-01A	22 years, male, white, stage:ia, alive, 413 days	2539.3
TCGA-SB-A76C-01A	38 years, male, white, alive, 42 days	2521.6
TCGA-XY-A9T9-01A	37 years, male, white, stage:is, alive, 281 days	2452.6
TCGA-XE-AANV-01A	52 years, male, stage:ib, alive, 1701 days	2409.3
TCGA-2G-AAHT-01A	32 years, male, white, stage:is, alive, 542 days	2301.0
TCGA-2G-AAH8-01A	45 years, male, white, stage:iiic, alive, 2248 days	2230.3
TCGA-2G-AAGK-01A	20 years, male, white, stage:is, alive, 3621 days	2146.3
TCGA-2G-AAF6-01A	28 years, male, white, stage:is, alive, 3491 days	2089.1
TCGA-VF-A8AC-01A	29 years, male, white, stage:ia, alive, 1083 days	2040.4
TCGA-2G-AAHL-01A	26 years, male, white, stage:i, alive, 7081 days	1901.7
TCGA-2G-AAL5-01A	31 years, male, white, stage:i, alive, 7437 days	1881.1
TCGA-2G-AAEW-01A	31 years, male, white, stage:is, dead, 618 days	1807.1
TCGA-SO-A8JP-01A	29 years, male, white, stage:i, alive, 540 days	1530.3
TCGA-2G-AAF1-01A	28 years, male, asian, stage:is, alive, 1403 days	1260.5
TCGA-4K-AA1G-01A	34 years, male, white, stage:is, alive, 436 days	1108.1
TCGA-2G-AAHP-01A	31 years, male, white, stage:is, alive, 5667 days	541.0
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TESTIS CANCER - Protein expressionⁱ A mouse-over function shows sample information and annotation data. Click on an image to view it in a full screen mode. Samples can be filtered based on level of antibody staining by selecting one or several of the following categories: high, medium, low and not detected. The assay and annotation is described here. Note that samples used for immunohistochemistry by the Human Protein Atlas do not correspond to samples in the TCGA dataset.

Antibody stainingⁱ Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high. This score is based on the staining intensity and fraction of stained cells. Read more	Antibody HPA069328	Antibody CAB016241
Staining
High
Medium
Low
Not detected
Intensity
Strong
Moderate
Weak
Negative
Quantity
>75%
75%-25%
<25%
None
Location
Nuclear
Cytoplasmic/membranous
Cytoplasmic/membranous,nuclear
None
Click images for details

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.