Expression of MT-ND1 in glioma - The Human Protein Atlas

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MT-ND1

SUMMARY

TISSUE

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PATHOLOGY

BRAIN

BLOOD

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GLIOMA - Interactive survival scatter plotⁱ

The Survival Scatter plot shows the clinical status (i.e. dead or alive) for all individuals in the patient cohort, based on the same data that underlies the corresponding Kaplan-Meier plots. Patients that are alive at last time for follow-up are shown in blue and patients who have died during the study are shown in red.

The x-axis shows the expression levels (FPKM) of the investigated gene in the tumor tissue at the time of diagnosis. The y-axis shows the follow-up time after diagnosis (years). Both axes are complimented with kernel density curves demonstrating the data density over the axes. The top density plot shows the expression levels (FPKM) distribution among dead (red) and alive patients (blue). The right density plot shows the data density of the survived years of dead patients with high and low expression levels respectively, stratified using the cutoff indicated by the vertical dashed line through the Survival Scatter plot. This cutoff is automatically defined based on the FPKM cutoff that minimizes the p-score. The cutoff can be changed by dragging the vertical line or by entering a cutoff value in the square labeled "Current cut-off".

Under the Survival Scatter plot the p-score landscape (black curve; left axis) is shown together with dead median separation (red curve; right axis). Dead median separation is the difference in median mRNA expression between patients who have died with high and low expression, respectively. It is calculated as follows: median FPKM expression of dead patients with high expression - median FPKM expression of dead patients with low expression. This is intended to aid the user in visually exploring custom cutoffs and the associated p-scores and dead median separation.

Individual patient data is displayed and can be filtered by clicking on one or more of the category buttons on the top of the page. Categories describing expression level and patient information include: high, low, alive, dead, female, male and tumor stages. The scale of the x-axis can be toggled between linear and log-scale by clicking on the "x log" button. Mouse-over function shows TCGA ID, patient information and mRNA expression (FPKM) for each patient.

& Survival analysisⁱ

MT-ND1 is not prognostic in glioma

Stage:

Survival analysis

Current cut offⁱ:
Best expression cut offⁱ: 2846.26
Median expressionⁱ: N/A
Median follow up timeⁱ: N/A
P scoreⁱ N/A
3-year survival highⁱ N/A
3-year survival lowⁱ N/A

TCGA RNA samplesⁱ

Average FPKM

2643.2

Number of samples

153

Samples

Sample	Description	FPKM
TCGA-06-0141-01A	62 years, male, white, dead, 313 days	10262.1
TCGA-06-0744-01A	67 years, male, white, dead, 1426 days	9468.2
TCGA-06-2561-01A	53 years, female, white, dead, 537 days	7120.8
TCGA-27-2519-01A	48 years, male, white, dead, 550 days	7103.2
TCGA-27-1835-01A	53 years, female, white, dead, 648 days	6524.4
TCGA-15-0742-01A	65 years, male, white, dead, 419 days	6381.6
TCGA-06-0132-01A	49 years, male, white, dead, 771 days	6361.4
TCGA-06-0743-01A	69 years, male, white, dead, 803 days	6339.2
TCGA-06-0649-01B	73 years, female, black or african american, dead, 64 days	5792.3
TCGA-06-0238-01A	46 years, male, white, dead, 405 days	5530.8
TCGA-19-1787-01B	49 years, male, white, dead, 385 days	5261.4
TCGA-27-1837-01A	36 years, male, white, dead, 427 days	5233.3
TCGA-26-1442-01A	43 years, male, white, alive, 953 days	5015.8
TCGA-06-0750-01A	43 years, male, white, dead, 28 days	4936.7
TCGA-27-1834-01A	56 years, male, white, dead, 1233 days	4870.1
TCGA-06-0184-01A	63 years, male, white, dead, 2126 days	4825.7
TCGA-16-0846-01A	85 years, male, white, dead, 119 days	4798.7
TCGA-14-0871-01A	75 years, female, white, dead, 880 days	4583.5
TCGA-19-2625-01A	76 years, female, white, dead, 124 days	4579.3
TCGA-32-2616-01A	48 years, female, white, dead, 224 days	4538.5
TCGA-32-1980-01A	72 years, male, white, dead, 36 days	4472.4
TCGA-19-2620-01A	70 years, male, white, dead, 148 days	4470.6
TCGA-06-0219-01A	67 years, male, white, dead, 22 days	4452.5
TCGA-06-0168-01A	59 years, female, white, dead, 598 days	4394.3
TCGA-14-1823-01A	58 years, female, white, dead, 543 days	4368.1
TCGA-06-0138-01A	43 years, male, white, dead, 737 days	4293.4
TCGA-06-0882-01A	30 years, male, white, dead, 632 days	4168.4
TCGA-27-1830-01A	57 years, male, white, dead, 154 days	4149.3
TCGA-06-0210-01A	72 years, female, white, dead, 225 days	3946.9
TCGA-06-1804-01A	81 years, female, white, dead, 414 days	3928.0
TCGA-12-0619-01A	60 years, male, white, dead, 1062 days	3919.4
TCGA-02-0047-01A	78 years, male, white, dead, 448 days	3810.4
TCGA-06-0156-01A	57 years, male, white, dead, 178 days	3787.1
TCGA-26-5136-01B	78 years, female, white, dead, 577 days	3748.1
TCGA-06-2557-01A	76 years, male, black or african american, dead, 33 days	3721.2
TCGA-16-1045-01B	49 years, female, white, dead, 883 days	3713.9
TCGA-06-0686-01A	53 years, male, white, dead, 432 days	3662.6
TCGA-06-0749-01A	50 years, male, black or african american, dead, 82 days	3647.4
TCGA-06-2558-01A	75 years, female, white, dead, 380 days	3557.0
TCGA-32-1982-01A	76 years, female, white, dead, 142 days	3499.5
TCGA-26-5132-01A	74 years, male, white, alive, 286 days	3439.6
TCGA-06-5411-01A	51 years, male, white, dead, 254 days	3387.4
TCGA-41-4097-01A	63 years, female, white, dead, 6 days	3326.4
TCGA-06-2570-01A	21 years, female, white, alive, 958 days	3226.6
TCGA-28-2513-01A	69 years, female, white, alive, 222 days	3207.0
TCGA-41-2571-01A	89 years, male, white, dead, 26 days	3140.9
TCGA-06-0157-01A	63 years, female, white, dead, 97 days	3093.7
TCGA-12-0616-01A	36 years, female, white, dead, 448 days	3019.7
TCGA-32-2634-01A	82 years, male, white, alive, 693 days	2961.6
TCGA-28-1753-01A	53 years, male, white, alive, 37 days	2937.2
TCGA-06-0645-01A	56 years, female, white, dead, 175 days	2894.0
TCGA-06-0178-01A	39 years, male, white, dead, 2681 days	2850.2
TCGA-19-2624-01A	51 years, male, white, dead, 5 days	2842.3
TCGA-06-0139-01A	40 years, male, white, dead, 362 days	2837.6
TCGA-41-2572-01A	67 years, male, white, dead, 406 days	2836.5
TCGA-26-5135-01A	72 years, female, white, dead, 270 days	2808.5
TCGA-06-0187-01A	69 years, male, white, dead, 828 days	2769.0
TCGA-06-2562-01A	81 years, male, white, dead, 382 days	2763.0
TCGA-26-5134-01A	74 years, male, white, alive, 167 days	2736.6
TCGA-28-2499-01A	59 years, male, white, dead, 95 days	2714.8
TCGA-14-0787-01A	69 years, male, asian, dead, 68 days	2677.1
TCGA-28-1747-01C	44 years, male, white, dead, 77 days	2665.6
TCGA-27-2528-01A	62 years, male, white, dead, 480 days	2634.9
TCGA-06-0646-01A	61 years, male, white, dead, 175 days	2634.4
TCGA-32-2615-01A	62 years, male, white, dead, 485 days	2598.9
TCGA-14-0817-01A	69 years, female, white, dead, 164 days	2560.4
TCGA-76-4929-01A	76 years, female, white, dead, 111 days	2531.5
TCGA-06-2569-01A	24 years, female, black or african american, alive, 13 days	2518.0
TCGA-32-1970-01A	59 years, male, white, dead, 468 days	2512.6
TCGA-26-5133-01A	59 years, male, white, alive, 452 days	2476.0
TCGA-06-0158-01A	73 years, male, white, dead, 329 days	2470.0
TCGA-76-4926-01B	68 years, male, white, dead, 138 days	2357.2
TCGA-32-2632-01A	80 years, male, white, dead, 269 days	2353.6
TCGA-06-0125-01A	63 years, female, white, dead, 1448 days	2341.5
TCGA-06-2564-01A	50 years, male, white, alive, 181 days	2302.6
TCGA-06-0745-01A	59 years, male, white, dead, 239 days	2301.6
TCGA-02-2483-01A	43 years, male, asian, alive, 466 days	2300.8
TCGA-14-0790-01B	64 years, female, white, dead, 419 days	2242.0
TCGA-06-0130-01A	54 years, male, white, dead, 394 days	2166.7
TCGA-12-0618-01A	49 years, male, white, dead, 395 days	2129.8
TCGA-06-0747-01A	53 years, male, white, dead, 82 days	2128.8
TCGA-28-2514-01A	45 years, male, asian, alive, 160 days	2115.9
TCGA-06-0878-01A	74 years, male, white, alive, 218 days	2098.5
TCGA-12-0821-01A	62 years, male, white, dead, 323 days	2063.1
TCGA-19-2629-01A	60 years, male, white, dead, 737 days	2062.1
TCGA-15-1444-01A	21 years, male, white, dead, 1537 days	2057.1
TCGA-19-1390-01A	63 years, female, white, dead, 772 days	2038.7
TCGA-27-2524-01A	56 years, male, white, dead, 231 days	1946.5
TCGA-06-5418-01A	75 years, female, white, dead, 83 days	1930.7
TCGA-27-1832-01A	59 years, female, white, dead, 300 days	1901.2
TCGA-08-0386-01A	74 years, male, white, dead, 548 days	1873.4
TCGA-41-3915-01A	48 years, male, white, dead, 360 days	1864.6
TCGA-06-0129-01A	30 years, male, asian, dead, 1024 days	1862.8
TCGA-06-5416-01A	23 years, female, white, alive, 204 days	1859.3
TCGA-19-4065-01A	36 years, male, white, alive, 214 days	1837.9
TCGA-06-5410-01A	72 years, female, white, dead, 108 days	1831.0
TCGA-14-0781-01B	49 years, male, black or african american, dead, 29 days	1811.0
TCGA-26-5139-01A	65 years, female, white, alive, 48 days	1752.0
TCGA-12-1597-01B	62 years, female, white, dead, 675 days	1736.1
TCGA-19-2619-01A	55 years, female, black or african american, alive, 294 days	1729.4
TCGA-06-2559-01A	83 years, male, white, dead, 150 days	1729.3
TCGA-32-4213-01A	47 years, female, white, alive, 604 days	1719.8
TCGA-32-2638-01A	67 years, male, white, dead, 766 days	1718.0
TCGA-06-2565-01A	59 years, male, asian, dead, 506 days	1698.7
TCGA-06-0190-01A	62 years, male, white, dead, 317 days	1668.6
TCGA-14-1825-01A	70 years, male, white, dead, 232 days	1628.4
TCGA-14-0789-01A	54 years, male, white, dead, 342 days	1624.2
TCGA-76-4925-01A	76 years, male, white, dead, 146 days	1609.3
TCGA-14-2554-01A	52 years, female, white, dead, 532 days	1604.4
TCGA-06-2567-01A	65 years, male, white, dead, 133 days	1600.7
TCGA-06-5858-01A	45 years, female, white, alive, 187 days	1539.3
TCGA-27-2521-01A	34 years, male, white, dead, 510 days	1531.0
TCGA-06-2563-01A	72 years, female, white, alive, 932 days	1514.2
TCGA-14-1829-01A	57 years, male, black or african american, alive, 218 days	1476.3
TCGA-28-5220-01A	67 years, male, white, dead, 388 days	1333.2
TCGA-28-5216-01A	52 years, male, white, alive, 415 days	1326.6
TCGA-28-5207-01A	71 years, male, white, dead, 343 days	1295.1
TCGA-06-0644-01A	71 years, male, black or african american, dead, 384 days	1286.7
TCGA-06-0211-01B	47 years, male, white, dead, 360 days	1261.1
TCGA-06-0174-01A	54 years, male, white, dead, 98 days	1246.1
TCGA-76-4928-01B	85 years, female, white, dead, 94 days	1243.5
TCGA-76-4931-01A	70 years, female, white, dead, 279 days	1238.7
TCGA-27-2526-01A	79 years, female, white, dead, 87 days	1233.1
TCGA-28-5218-01A	63 years, male, white, dead, 157 days	1200.4
TCGA-06-5412-01A	78 years, female, white, dead, 138 days	1180.7
TCGA-14-1034-01A	60 years, female, dead, 485 days	1176.5
TCGA-28-5215-01A	62 years, female, white, dead, 335 days	1157.7
TCGA-28-5209-01A	66 years, female, white, alive, 77 days	1154.8
TCGA-41-5651-01A	59 years, female, black or african american, dead, 460 days	1121.2
TCGA-27-1831-01A	66 years, male, white, dead, 505 days	1120.9
TCGA-06-5414-01A	61 years, male, white, alive, 273 days	1090.7
TCGA-28-2509-01A	77 years, female, white, alive, 145 days	1045.7
TCGA-76-4927-01A	58 years, male, white, dead, 535 days	935.1
TCGA-02-0055-01A	62 years, female, white, dead, 76 days	930.6
TCGA-76-4932-01A	50 years, female, white, dead, 1458 days	916.7
TCGA-02-2486-01A	64 years, male, white, dead, 618 days	854.6
TCGA-19-5960-01A	56 years, male, white, dead, 455 days	832.8
TCGA-02-2485-01A	53 years, male, black or african american, alive, 470 days	803.0
TCGA-12-3650-01A	46 years, male, white, dead, 333 days	765.5
TCGA-06-5417-01A	45 years, female, white, alive, 155 days	759.7
TCGA-27-2523-01A	63 years, male, white, dead, 489 days	750.7
TCGA-12-5299-01A	56 years, female, white, dead, 98 days	717.3
TCGA-06-5413-01A	67 years, male, white, alive, 268 days	646.5
TCGA-06-5859-01A	63 years, male, white, alive, 139 days	641.5
TCGA-28-5204-01A	72 years, male, white, dead, 454 days	576.2
TCGA-06-5856-01A	58 years, male, white, dead, 114 days	558.4
TCGA-12-5295-01A	60 years, female, white, dead, 454 days	555.1
TCGA-12-3653-01A	34 years, female, white, dead, 442 days	474.3
TCGA-06-5408-01A	54 years, female, white, dead, 357 days	473.9
TCGA-12-3652-01A	60 years, male, white, dead, 1062 days	450.2
TCGA-28-5213-01A	72 years, male, white, alive, 951 days	441.4
TCGA-28-5208-01A	52 years, male, white, dead, 544 days	336.7
TCGA-32-5222-01A	66 years, male, white, dead, 585 days	313.3
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GLIOMA - Protein expressionⁱ A mouse-over function shows sample information and annotation data. Click on an image to view it in a full screen mode. Samples can be filtered based on level of antibody staining by selecting one or several of the following categories: high, medium, low and not detected. The assay and annotation is described here. Note that samples used for immunohistochemistry by the Human Protein Atlas do not correspond to samples in the TCGA dataset.

Antibody stainingⁱ Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high. This score is based on the staining intensity and fraction of stained cells. Read more	Antibody HPA066847	Antibody CAB033779
Staining
High
Medium
Low
Not detected
Intensity
Strong
Moderate
Weak
Negative
Quantity
>75%
75%-25%
<25%
None
Location
Nuclear
Cytoplasmic/membranous
Cytoplasmic/membranous,nuclear
None
Click images for details

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.