Expression of MT-ND1 in pancreatic cancer

PANCREATIC CANCER - Interactive survival scatter plotⁱ

The Survival Scatter plot shows the clinical status (i.e. dead or alive) for all individuals in the patient cohort, based on the same data that underlies the corresponding Kaplan-Meier plots. Patients that are alive at last time for follow-up are shown in blue and patients who have died during the study are shown in red.

The x-axis shows the expression levels (FPKM) of the investigated gene in the tumor tissue at the time of diagnosis. The y-axis shows the follow-up time after diagnosis (years). Both axes are complimented with kernel density curves demonstrating the data density over the axes. The top density plot shows the expression levels (FPKM) distribution among dead (red) and alive patients (blue). The right density plot shows the data density of the survived years of dead patients with high and low expression levels respectively, stratified using the cutoff indicated by the vertical dashed line through the Survival Scatter plot. This cutoff is automatically defined based on the FPKM cutoff that minimizes the p-score. The cutoff can be changed by dragging the vertical line or by entering a cutoff value in the square labeled "Current cut-off".

Under the Survival Scatter plot the p-score landscape (black curve; left axis) is shown together with dead median separation (red curve; right axis). Dead median separation is the difference in median mRNA expression between patients who have died with high and low expression, respectively. It is calculated as follows: median FPKM expression of dead patients with high expression - median FPKM expression of dead patients with low expression. This is intended to aid the user in visually exploring custom cutoffs and the associated p-scores and dead median separation.

Individual patient data is displayed and can be filtered by clicking on one or more of the category buttons on the top of the page. Categories describing expression level and patient information include: high, low, alive, dead, female, male and tumor stages. The scale of the x-axis can be toggled between linear and log-scale by clicking on the "x log" button. Mouse-over function shows TCGA ID, patient information and mRNA expression (FPKM) for each patient.

& Survival analysisⁱ

MT-ND1 is prognostic, high expression is favorable in pancreatic cancer

Stage:

Survival analysis

Current cut offⁱ:
Best expression cut offⁱ: 1790.83
Median expressionⁱ: N/A
Median follow up timeⁱ: N/A
P scoreⁱ N/A
5-year survival highⁱ N/A
5-year survival lowⁱ N/A

TCGA RNA samplesⁱ

Average FPKM

3334.8

Number of samples

176

Samples

Sample	Description	FPKM
TCGA-HV-A5A3-01A	50 years, male, asian, stage:iia, dead, 128 days	10344.4
TCGA-FB-AAQ3-01A	65 years, female, white, stage:iib, dead, 31 days	9381.1
TCGA-H8-A6C1-01A	53 years, male, white, stage:iia, alive, 671 days	9299.6
TCGA-2J-AABH-01A	61 years, male, white, stage:iia, alive, 1287 days	8428.2
TCGA-LB-A7SX-01A	74 years, female, black or african american, stage:iib, dead, 393 days	8178.3
TCGA-FB-AAPY-01A	71 years, male, white, stage:iib, dead, 1059 days	7839.4
TCGA-2J-AABK-01A	71 years, male, white, stage:iib, alive, 484 days	7786.6
TCGA-2L-AAQM-01A	52 years, male, white, stage:iib, alive, 1383 days	7125.3
TCGA-3A-A9IL-01A	39 years, female, white, stage:i, alive, 2741 days	7090.3
TCGA-HV-A5A5-01A	61 years, female, asian, stage:iib, alive, 289 days	6953.3
TCGA-IB-A5SP-01A	77 years, male, white, stage:iia, alive, 482 days	6527.0
TCGA-3A-A9IN-01A	62 years, female, white, stage:ib, alive, 2084 days	6498.7
TCGA-HZ-A8P1-01A	81 years, male, white, stage:ib, alive, 7 days	6437.2
TCGA-HV-A5A6-01A	65 years, female, asian, stage:iib, dead, 2036 days	6212.9
TCGA-US-A779-01A	54 years, female, white, stage:iib, dead, 511 days	6018.4
TCGA-Q3-AA2A-01A	64 years, female, white, stage:ib, alive, 95 days	5793.9
TCGA-2L-AAQE-01A	56 years, male, white, stage:iib, dead, 684 days	5747.3
TCGA-RB-A7B8-01A	81 years, female, white, stage:iib, dead, 466 days	5664.8
TCGA-3A-A9I7-01A	45 years, male, black or african american, stage:iib, alive, 1323 days	5611.3
TCGA-2J-AABT-01A	72 years, female, white, stage:iib, alive, 319 days	5607.3
TCGA-2J-AABE-01A	73 years, male, white, stage:iia, alive, 676 days	5585.7
TCGA-FB-AAPZ-01A	54 years, male, white, stage:iib, alive, 716 days	5561.4
TCGA-2L-AAQL-01A	82 years, male, white, stage:iib, dead, 292 days	5442.2
TCGA-M8-A5N4-01A	48 years, female, stage:iia, alive, 584 days	5434.4
TCGA-Q3-A5QY-01A	58 years, male, white, stage:iib, alive, 416 days	5353.2
TCGA-FB-AAQ6-01A	85 years, male, white, stage:ia, dead, 244 days	5343.2
TCGA-2L-AAQJ-01A	49 years, female, white, stage:iii, dead, 394 days	5334.4
TCGA-2J-AABI-01A	55 years, female, white, stage:iia, alive, 969 days	5297.7
TCGA-F2-A44H-01A	65 years, male, white, stage:iia, alive, 586 days	5253.2
TCGA-HZ-A4BK-01A	72 years, male, white, stage:iib, alive, 657 days	5068.1
TCGA-HZ-A9TJ-01A	70 years, male, white, stage:iv, alive, 603 days	5031.7
TCGA-FB-AAQ2-01A	81 years, female, white, stage:iib, dead, 153 days	4916.7
TCGA-US-A77G-01A	64 years, male, white, stage:iib, dead, 12 days	4902.6
TCGA-FB-AAPS-01A	62 years, female, white, stage:iib, alive, 228 days	4736.8
TCGA-3A-A9IS-01A	67 years, male, white, stage:ib, alive, 998 days	4646.7
TCGA-FB-A545-01A	72 years, female, white, stage:iib, dead, 732 days	4590.4
TCGA-XD-AAUI-01A	50 years, female, white, stage:iib, dead, 366 days	4580.0
TCGA-3A-A9IV-01A	59 years, female, white, stage:ib, alive, 1103 days	4572.4
TCGA-XD-AAUH-01A	57 years, female, white, stage:iib, alive, 395 days	4412.5
TCGA-2J-AABA-01A	55 years, male, white, stage:iib, dead, 607 days	4401.8
TCGA-IB-AAUO-01A	64 years, female, white, stage:iib, dead, 239 days	4365.3
TCGA-H6-A45N-01A	88 years, female, white, stage:iib, dead, 421 days	4317.4
TCGA-2J-AABU-01A	56 years, male, white, stage:iib, dead, 277 days	4259.9
TCGA-FB-AAQ1-01A	49 years, male, white, stage:iib, dead, 123 days	4256.9
TCGA-3E-AAAZ-01A	71 years, male, white, stage:iia, dead, 2182 days	4253.2
TCGA-HV-AA8V-01A	50 years, male, asian, stage:iib, alive, 920 days	4208.2
TCGA-L1-A7W4-01A	48 years, female, white, stage:iib, dead, 278 days	4185.4
TCGA-HZ-A49G-01A	58 years, female, white, stage:iib, alive, 660 days	4150.9
TCGA-3A-A9I9-01A	67 years, male, white, stage:iia, dead, 634 days	4098.0
TCGA-2J-AAB1-01A	65 years, male, white, stage:iib, dead, 66 days	4072.5
TCGA-XN-A8T5-01A	53 years, female, white, stage:ib, alive, 720 days	4051.9
TCGA-HZ-8637-01A	76 years, female, white, stage:iib, dead, 517 days	4045.7
TCGA-HZ-A49H-01A	68 years, female, white, stage:iib, alive, 491 days	3996.6
TCGA-S4-A8RP-01A	77 years, female, white, stage:iib, dead, 702 days	3870.9
TCGA-US-A77E-01A	73 years, male, white, stage:iib, dead, 430 days	3855.6
TCGA-3A-A9IO-01A	56 years, male, white, alive, 1942 days	3829.7
TCGA-IB-7649-01A	73 years, female, stage:iib, dead, 467 days	3798.6
TCGA-FB-AAQ0-01A	68 years, male, white, stage:iia, dead, 473 days	3701.6
TCGA-3A-A9IX-01A	40 years, male, white, stage:ia, alive, 1037 days	3670.5
TCGA-IB-A6UG-01A	65 years, male, white, stage:iib, dead, 41 days	3597.4
TCGA-IB-AAUQ-01A	50 years, male, white, stage:iib, dead, 183 days	3584.6
TCGA-XN-A8T3-01A	67 years, male, white, stage:ib, alive, 951 days	3572.2
TCGA-HZ-A77P-01A	77 years, male, white, stage:iib, alive, 330 days	3564.8
TCGA-XD-AAUG-01A	66 years, female, white, stage:iv, alive, 420 days	3559.1
TCGA-FB-AAPQ-01A	65 years, male, white, stage:iib, dead, 1130 days	3538.0
TCGA-3A-A9IJ-01A	65 years, male, white, stage:ib, alive, 1854 days	3494.6
TCGA-F2-A44G-01A	79 years, female, white, stage:iib, dead, 233 days	3482.2
TCGA-IB-AAUW-01A	63 years, female, white, stage:iib, dead, 230 days	3406.4
TCGA-3A-A9I5-01A	58 years, male, white, alive, 1794 days	3357.1
TCGA-2J-AABO-01A	43 years, male, white, stage:iib, alive, 440 days	3305.2
TCGA-2J-AABR-01A	60 years, female, white, stage:iia, alive, 438 days	3286.0
TCGA-2L-AAQI-01A	66 years, male, white, stage:iib, dead, 103 days	3270.6
TCGA-FB-A4P5-01A	69 years, female, white, stage:iib, dead, 179 days	3240.8
TCGA-IB-A6UF-01A	63 years, male, white, stage:iib, alive, 666 days	3231.7
TCGA-S4-A8RM-01A	67 years, male, white, stage:iib, alive, 737 days	3222.9
TCGA-2J-AABF-01A	73 years, male, white, stage:iib, dead, 691 days	3187.7
TCGA-FB-A78T-01A	71 years, female, white, stage:iib, dead, 375 days	3184.6
TCGA-FB-A7DR-01A	48 years, male, asian, stage:iia, dead, 353 days	3177.5
TCGA-US-A776-01A	61 years, male, white, stage:iia, alive, 1216 days	3176.1
TCGA-IB-AAUR-01A	67 years, male, white, stage:iib, alive, 338 days	3157.6
TCGA-IB-8126-01A	80 years, female, white, stage:iii, alive, 462 days	3141.8
TCGA-IB-AAUS-01A	84 years, female, white, stage:iib, alive, 225 days	3088.1
TCGA-HZ-8519-01A	73 years, male, white, stage:ia, alive, 454 days	3070.5
TCGA-3E-AAAY-01A	67 years, male, white, stage:iib, alive, 2285 days	3069.9
TCGA-HZ-8315-01A	54 years, female, white, stage:iia, dead, 299 days	3059.3
TCGA-HZ-8317-01A	69 years, female, white, stage:iib, dead, 378 days	3040.9
TCGA-HZ-7289-01A	77 years, male, white, stage:iib, dead, 661 days	3040.3
TCGA-3A-A9IB-01A	69 years, female, white, stage:iib, dead, 224 days	3033.5
TCGA-2J-AAB9-01A	71 years, female, white, stage:iib, dead, 627 days	3010.2
TCGA-2L-AAQA-01A	76 years, male, white, stage:iib, dead, 143 days	2987.6
TCGA-3A-A9IU-01A	65 years, male, white, stage:iib, dead, 458 days	2979.3
TCGA-F2-6880-01A	70 years, male, white, stage:iib, alive, 289 days	2971.8
TCGA-FB-AAPP-01A	71 years, male, white, stage:iib, dead, 485 days	2942.7
TCGA-IB-AAUT-01A	65 years, male, white, stage:iib, alive, 287 days	2935.8
TCGA-IB-A7M4-01A	81 years, male, white, stage:iib, alive, 483 days	2926.9
TCGA-IB-AAUN-01A	74 years, female, white, stage:ib, dead, 144 days	2855.7
TCGA-HZ-8638-01A	84 years, female, white, stage:ia, dead, 151 days	2846.2
TCGA-FB-A4P6-01A	54 years, male, white, stage:iib, alive, 767 days	2839.5
TCGA-IB-A5SQ-01A	56 years, female, white, stage:ib, dead, 219 days	2792.2
TCGA-RL-AAAS-01A	60 years, female, white, stage:ib, alive, 9 days	2718.5
TCGA-F2-A8YN-01A	76 years, male, white, stage:iia, alive, 517 days	2705.5
TCGA-IB-A5SO-01A	71 years, male, white, stage:iib, dead, 365 days	2693.1
TCGA-YH-A8SY-01A	73 years, female, white, alive, 388 days	2691.3
TCGA-3A-A9IR-01A	64 years, female, white, stage:ib, alive, 1542 days	2674.9
TCGA-US-A77J-01A	81 years, female, white, stage:iib, dead, 568 days	2646.9
TCGA-IB-AAUM-01A	76 years, male, white, stage:iib, alive, 8 days	2644.3
TCGA-HZ-A77Q-01A	55 years, female, white, stage:iib, alive, 33 days	2643.9
TCGA-LB-A9Q5-01A	63 years, female, white, stage:iib, dead, 313 days	2622.3
TCGA-HV-A5A4-01A	72 years, female, asian, stage:iia, alive, 232 days	2592.8
TCGA-IB-AAUV-01A	49 years, male, white, stage:iib, alive, 404 days	2535.6
TCGA-IB-AAUU-01A	35 years, male, white, stage:iib, alive, 245 days	2523.1
TCGA-3A-A9J0-01A	75 years, male, white, stage:iib, alive, 743 days	2515.1
TCGA-HV-AA8X-01A	75 years, female, asian, stage:iib, dead, 532 days	2512.8
TCGA-S4-A8RO-01A	75 years, female, white, stage:iib, alive, 525 days	2480.6
TCGA-2J-AAB4-01A	48 years, male, white, stage:iib, alive, 729 days	2454.4
TCGA-PZ-A5RE-01A	44 years, female, white, stage:iib, dead, 470 days	2410.8
TCGA-HZ-7923-01A	65 years, male, white, stage:iia, alive, 314 days	2391.8
TCGA-3A-A9IH-01A	66 years, female, white, stage:ia, alive, 1021 days	2378.2
TCGA-IB-AAUP-01A	68 years, male, white, stage:iib, alive, 431 days	2376.0
TCGA-YB-A89D-01A	59 years, male, white, stage:iib, alive, 350 days	2374.2
TCGA-Z5-AAPL-01A	74 years, female, white, stage:iia, alive, 467 days	2357.7
TCGA-FB-AAPU-01A	41 years, female, asian, stage:iia, dead, 381 days	2297.8
TCGA-HV-A7OP-01A	72 years, male, asian, stage:iib, alive, 978 days	2289.2
TCGA-FB-A5VM-01A	74 years, male, white, stage:ib, dead, 498 days	2190.5
TCGA-HZ-A4BH-01A	75 years, male, white, stage:iib, alive, 194 days	2174.1
TCGA-IB-7885-01A	78 years, female, white, stage:iib, alive, 1257 days	2169.4
TCGA-2J-AABV-01A	74 years, male, white, stage:iib, dead, 652 days	2164.3
TCGA-YY-A8LH-01A	61 years, female, white, stage:iib, alive, 2016 days	2124.7
TCGA-RB-AA9M-01A	43 years, male, white, stage:iib, alive, 286 days	2120.3
TCGA-XD-AAUL-01A	56 years, male, white, stage:iia, alive, 498 days	2081.7
TCGA-IB-7897-01A	54 years, female, white, stage:iib, dead, 486 days	2070.3
TCGA-HZ-8001-01A	69 years, male, white, stage:iii, alive, 706 days	2050.3
TCGA-IB-7887-01A	62 years, female, white, stage:iib, dead, 110 days	2040.7
TCGA-US-A774-01A	76 years, female, white, stage:iib, dead, 695 days	2034.5
TCGA-3A-A9IZ-01A	47 years, male, white, stage:iib, dead, 308 days	1940.8
TCGA-IB-A5ST-01A	64 years, female, white, stage:iib, alive, 635 days	1841.7
TCGA-HZ-7924-01A	60 years, female, white, stage:iia, alive, 840 days	1836.1
TCGA-LB-A8F3-01A	64 years, female, black or african american, stage:iia, alive, 379 days	1822.1
TCGA-HZ-A49I-01A	77 years, male, white, stage:iib, dead, 308 days	1759.5
TCGA-IB-A7LX-01A	57 years, male, white, stage:iib, dead, 250 days	1733.5
TCGA-IB-7645-01A	44 years, female, stage:iib, dead, 1502 days	1733.4
TCGA-HV-A7OL-01A	70 years, male, asian, stage:iia, alive, 252 days	1727.7
TCGA-F2-7276-01A	64 years, male, white, stage:iib, dead, 216 days	1708.4
TCGA-IB-7654-01A	80 years, male, white, stage:iib, dead, 476 days	1686.1
TCGA-HZ-A77O-01A	77 years, female, white, stage:iib, dead, 160 days	1677.5
TCGA-IB-7889-01A	86 years, female, white, stage:iib, dead, 481 days	1652.2
TCGA-OE-A75W-01A	75 years, male, white, stage:iia, dead, 267 days	1576.2
TCGA-IB-8127-01A	59 years, male, white, stage:iib, alive, 522 days	1549.3
TCGA-H6-8124-01A	56 years, female, white, stage:iib, alive, 392 days	1502.5
TCGA-HZ-7926-01A	57 years, male, black or african american, stage:iib, dead, 518 days	1446.0
TCGA-IB-7888-01A	66 years, female, black or african american, stage:iia, dead, 1332 days	1406.0
TCGA-2J-AAB6-01A	75 years, male, white, stage:iia, dead, 293 days	1402.7
TCGA-HZ-7925-01A	66 years, male, white, stage:iib, dead, 614 days	1395.8
TCGA-F2-A7TX-01A	77 years, male, white, stage:iib, dead, 95 days	1388.6
TCGA-HZ-7920-01A	71 years, male, white, stage:ib, dead, 236 days	1375.5
TCGA-HZ-8002-01A	61 years, male, white, stage:iib, dead, 366 days	1349.3
TCGA-3A-A9IC-01A	61 years, female, white, stage:iib, dead, 738 days	1311.0
TCGA-HZ-8636-01A	58 years, female, white, stage:iv, dead, 545 days	1282.0
TCGA-F2-6879-01A	57 years, male, white, stage:iib, dead, 334 days	1281.0
TCGA-HZ-8003-01A	65 years, female, white, stage:iib, dead, 596 days	1239.8
TCGA-IB-7651-01A	64 years, female, white, stage:iib, dead, 603 days	1210.6
TCGA-IB-7644-01A	65 years, female, white, stage:iv, dead, 394 days	1208.4
TCGA-IB-7646-01A	60 years, male, white, stage:iib, dead, 145 days	1150.7
TCGA-IB-A5SS-01A	64 years, female, white, stage:iib, dead, 460 days	1111.3
TCGA-2J-AAB8-01A	71 years, male, white, stage:iib, alive, 80 days	1061.2
TCGA-HZ-7919-01A	52 years, female, white, stage:iib, dead, 593 days	1049.5
TCGA-IB-7891-01A	49 years, female, white, stage:iib, dead, 913 days	1009.7
TCGA-IB-7652-01A	49 years, female, asian, stage:iib, alive, 1116 days	1007.0
TCGA-F2-7273-01A	54 years, male, black or african american, stage:iib, dead, 592 days	927.3
TCGA-HZ-8005-01A	81 years, male, white, stage:iib, dead, 120 days	918.6
TCGA-HZ-7922-01A	61 years, female, white, stage:iib, alive, 4 days	903.4
TCGA-HZ-7918-01A	72 years, male, white, stage:iib, alive, 969 days	877.9
TCGA-IB-7890-01A	73 years, male, stage:ib, dead, 598 days	874.8
TCGA-IB-7893-01A	64 years, male, white, stage:iia, dead, 117 days	781.5
TCGA-2J-AABP-01A	58 years, female, white, stage:iib, alive, 463 days	771.7
TCGA-IB-7886-01A	80 years, male, white, stage:iib, dead, 123 days	461.9
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PANCREATIC CANCER - Protein expressionⁱ A mouse-over function shows sample information and annotation data. Click on an image to view it in a full screen mode. Samples can be filtered based on level of antibody staining by selecting one or several of the following categories: high, medium, low and not detected. The assay and annotation is described here. Note that samples used for immunohistochemistry by the Human Protein Atlas do not correspond to samples in the TCGA dataset.

Antibody stainingⁱ Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high. This score is based on the staining intensity and fraction of stained cells. Read more	Antibody HPA066847	Antibody CAB033779
Staining
High
Medium
Low
Not detected
Intensity
Strong
Moderate
Weak
Negative
Quantity
>75%
75%-25%
<25%
None
Location
Nuclear
Cytoplasmic/membranous
Cytoplasmic/membranous,nuclear
None
Click images for details