Expression of MT-ATP6 in pancreatic cancer

PANCREATIC CANCER - Interactive survival scatter plotⁱ

The Survival Scatter plot shows the clinical status (i.e. dead or alive) for all individuals in the patient cohort, based on the same data that underlies the corresponding Kaplan-Meier plots. Patients that are alive at last time for follow-up are shown in blue and patients who have died during the study are shown in red.

The x-axis shows the expression levels (FPKM) of the investigated gene in the tumor tissue at the time of diagnosis. The y-axis shows the follow-up time after diagnosis (years). Both axes are complimented with kernel density curves demonstrating the data density over the axes. The top density plot shows the expression levels (FPKM) distribution among dead (red) and alive patients (blue). The right density plot shows the data density of the survived years of dead patients with high and low expression levels respectively, stratified using the cutoff indicated by the vertical dashed line through the Survival Scatter plot. This cutoff is automatically defined based on the FPKM cutoff that minimizes the p-score. The cutoff can be changed by dragging the vertical line or by entering a cutoff value in the square labeled "Current cut-off".

Under the Survival Scatter plot the p-score landscape (black curve; left axis) is shown together with dead median separation (red curve; right axis). Dead median separation is the difference in median mRNA expression between patients who have died with high and low expression, respectively. It is calculated as follows: median FPKM expression of dead patients with high expression - median FPKM expression of dead patients with low expression. This is intended to aid the user in visually exploring custom cutoffs and the associated p-scores and dead median separation.

Individual patient data is displayed and can be filtered by clicking on one or more of the category buttons on the top of the page. Categories describing expression level and patient information include: high, low, alive, dead, female, male and tumor stages. The scale of the x-axis can be toggled between linear and log-scale by clicking on the "x log" button. Mouse-over function shows TCGA ID, patient information and mRNA expression (FPKM) for each patient.

& Survival analysisⁱ

MT-ATP6 is prognostic, high expression is favorable in pancreatic cancer

Stage:

Survival analysis

Current cut offⁱ:
Best expression cut offⁱ: 3087.43
Median expressionⁱ: N/A
Median follow up timeⁱ: N/A
P scoreⁱ N/A
5-year survival highⁱ N/A
5-year survival lowⁱ N/A

TCGA RNA samplesⁱ

Average FPKM

4887.7

Number of samples

176

Samples

Sample	Description	FPKM
TCGA-2J-AABK-01A	71 years, male, white, stage:iib, alive, 484 days	13023.3
TCGA-FB-AAQ1-01A	49 years, male, white, stage:iib, dead, 123 days	12150.0
TCGA-FB-AAPY-01A	71 years, male, white, stage:iib, dead, 1059 days	11651.7
TCGA-H8-A6C1-01A	53 years, male, white, stage:iia, alive, 671 days	11269.0
TCGA-2J-AABH-01A	61 years, male, white, stage:iia, alive, 1287 days	10987.4
TCGA-FB-AAQ3-01A	65 years, female, white, stage:iib, dead, 31 days	9739.9
TCGA-3A-A9IV-01A	59 years, female, white, stage:ib, alive, 1103 days	9673.7
TCGA-3A-A9IL-01A	39 years, female, white, stage:i, alive, 2741 days	9612.2
TCGA-Q3-AA2A-01A	64 years, female, white, stage:ib, alive, 95 days	9543.2
TCGA-HV-A5A5-01A	61 years, female, asian, stage:iib, alive, 289 days	9405.6
TCGA-RB-A7B8-01A	81 years, female, white, stage:iib, dead, 466 days	9198.1
TCGA-2L-AAQM-01A	52 years, male, white, stage:iib, alive, 1383 days	9039.7
TCGA-F2-A8YN-01A	76 years, male, white, stage:iia, alive, 517 days	9024.6
TCGA-3A-A9IN-01A	62 years, female, white, stage:ib, alive, 2084 days	8863.5
TCGA-LB-A7SX-01A	74 years, female, black or african american, stage:iib, dead, 393 days	8813.8
TCGA-HZ-A9TJ-01A	70 years, male, white, stage:iv, alive, 603 days	8763.7
TCGA-F2-A44H-01A	65 years, male, white, stage:iia, alive, 586 days	8560.4
TCGA-FB-AAPQ-01A	65 years, male, white, stage:iib, dead, 1130 days	8259.7
TCGA-IB-A5SP-01A	77 years, male, white, stage:iia, alive, 482 days	8248.4
TCGA-FB-AAPP-01A	71 years, male, white, stage:iib, dead, 485 days	7929.9
TCGA-2L-AAQJ-01A	49 years, female, white, stage:iii, dead, 394 days	7838.0
TCGA-FB-AAPU-01A	41 years, female, asian, stage:iia, dead, 381 days	7734.2
TCGA-XD-AAUI-01A	50 years, female, white, stage:iib, dead, 366 days	7625.6
TCGA-OE-A75W-01A	75 years, male, white, stage:iia, dead, 267 days	7595.0
TCGA-US-A779-01A	54 years, female, white, stage:iib, dead, 511 days	7590.8
TCGA-2J-AABE-01A	73 years, male, white, stage:iia, alive, 676 days	7547.1
TCGA-HZ-A8P1-01A	81 years, male, white, stage:ib, alive, 7 days	7534.7
TCGA-HV-A5A6-01A	65 years, female, asian, stage:iib, dead, 2036 days	7292.5
TCGA-HV-AA8V-01A	50 years, male, asian, stage:iib, alive, 920 days	7206.7
TCGA-HZ-8638-01A	84 years, female, white, stage:ia, dead, 151 days	7178.4
TCGA-2J-AABT-01A	72 years, female, white, stage:iib, alive, 319 days	7078.1
TCGA-FB-AAQ6-01A	85 years, male, white, stage:ia, dead, 244 days	7059.6
TCGA-3A-A9I9-01A	67 years, male, white, stage:iia, dead, 634 days	7010.6
TCGA-HZ-8637-01A	76 years, female, white, stage:iib, dead, 517 days	6862.4
TCGA-US-A77E-01A	73 years, male, white, stage:iib, dead, 430 days	6730.0
TCGA-Q3-A5QY-01A	58 years, male, white, stage:iib, alive, 416 days	6694.6
TCGA-2J-AAB1-01A	65 years, male, white, stage:iib, dead, 66 days	6443.4
TCGA-US-A776-01A	61 years, male, white, stage:iia, alive, 1216 days	6373.0
TCGA-HZ-A4BK-01A	72 years, male, white, stage:iib, alive, 657 days	6350.8
TCGA-M8-A5N4-01A	48 years, female, stage:iia, alive, 584 days	6260.0
TCGA-HZ-8315-01A	54 years, female, white, stage:iia, dead, 299 days	6232.3
TCGA-3E-AAAY-01A	67 years, male, white, stage:iib, alive, 2285 days	6226.1
TCGA-HZ-8519-01A	73 years, male, white, stage:ia, alive, 454 days	6126.0
TCGA-2L-AAQL-01A	82 years, male, white, stage:iib, dead, 292 days	6121.3
TCGA-IB-7649-01A	73 years, female, stage:iib, dead, 467 days	6083.0
TCGA-FB-AAQ2-01A	81 years, female, white, stage:iib, dead, 153 days	6076.4
TCGA-F2-A44G-01A	79 years, female, white, stage:iib, dead, 233 days	6067.1
TCGA-FB-AAPZ-01A	54 years, male, white, stage:iib, alive, 716 days	6034.8
TCGA-IB-AAUO-01A	64 years, female, white, stage:iib, dead, 239 days	6010.2
TCGA-FB-AAQ0-01A	68 years, male, white, stage:iia, dead, 473 days	5820.5
TCGA-HV-A5A3-01A	50 years, male, asian, stage:iia, dead, 128 days	5790.4
TCGA-HZ-A77P-01A	77 years, male, white, stage:iib, alive, 330 days	5787.4
TCGA-2J-AAB4-01A	48 years, male, white, stage:iib, alive, 729 days	5766.0
TCGA-2J-AABA-01A	55 years, male, white, stage:iib, dead, 607 days	5677.1
TCGA-3A-A9IS-01A	67 years, male, white, stage:ib, alive, 998 days	5611.7
TCGA-HZ-8317-01A	69 years, female, white, stage:iib, dead, 378 days	5575.3
TCGA-2J-AABF-01A	73 years, male, white, stage:iib, dead, 691 days	5567.1
TCGA-XD-AAUH-01A	57 years, female, white, stage:iib, alive, 395 days	5553.7
TCGA-IB-AAUQ-01A	50 years, male, white, stage:iib, dead, 183 days	5551.0
TCGA-2J-AAB8-01A	71 years, male, white, stage:iib, alive, 80 days	5497.2
TCGA-US-A77G-01A	64 years, male, white, stage:iib, dead, 12 days	5313.7
TCGA-3A-A9I5-01A	58 years, male, white, alive, 1794 days	5240.7
TCGA-HZ-A49H-01A	68 years, female, white, stage:iib, alive, 491 days	5211.4
TCGA-2J-AABR-01A	60 years, female, white, stage:iia, alive, 438 days	5189.2
TCGA-S4-A8RM-01A	67 years, male, white, stage:iib, alive, 737 days	5187.1
TCGA-3A-A9J0-01A	75 years, male, white, stage:iib, alive, 743 days	5119.3
TCGA-3A-A9I7-01A	45 years, male, black or african american, stage:iib, alive, 1323 days	5109.7
TCGA-HV-AA8X-01A	75 years, female, asian, stage:iib, dead, 532 days	5105.9
TCGA-2J-AABO-01A	43 years, male, white, stage:iib, alive, 440 days	5074.8
TCGA-PZ-A5RE-01A	44 years, female, white, stage:iib, dead, 470 days	5072.1
TCGA-YH-A8SY-01A	73 years, female, white, alive, 388 days	5018.2
TCGA-XN-A8T5-01A	53 years, female, white, stage:ib, alive, 720 days	4988.2
TCGA-HZ-7289-01A	77 years, male, white, stage:iib, dead, 661 days	4878.8
TCGA-H6-A45N-01A	88 years, female, white, stage:iib, dead, 421 days	4864.8
TCGA-3A-A9IX-01A	40 years, male, white, stage:ia, alive, 1037 days	4862.3
TCGA-IB-A5SO-01A	71 years, male, white, stage:iib, dead, 365 days	4856.2
TCGA-2J-AABU-01A	56 years, male, white, stage:iib, dead, 277 days	4852.5
TCGA-3A-A9IH-01A	66 years, female, white, stage:ia, alive, 1021 days	4780.4
TCGA-IB-A6UF-01A	63 years, male, white, stage:iib, alive, 666 days	4749.4
TCGA-XD-AAUG-01A	66 years, female, white, stage:iv, alive, 420 days	4686.3
TCGA-2L-AAQI-01A	66 years, male, white, stage:iib, dead, 103 days	4641.5
TCGA-2J-AABI-01A	55 years, female, white, stage:iia, alive, 969 days	4640.4
TCGA-FB-AAPS-01A	62 years, female, white, stage:iib, alive, 228 days	4556.2
TCGA-IB-A6UG-01A	65 years, male, white, stage:iib, dead, 41 days	4514.8
TCGA-IB-8126-01A	80 years, female, white, stage:iii, alive, 462 days	4499.3
TCGA-L1-A7W4-01A	48 years, female, white, stage:iib, dead, 278 days	4456.7
TCGA-2L-AAQE-01A	56 years, male, white, stage:iib, dead, 684 days	4454.1
TCGA-HZ-A49G-01A	58 years, female, white, stage:iib, alive, 660 days	4413.5
TCGA-S4-A8RP-01A	77 years, female, white, stage:iib, dead, 702 days	4408.4
TCGA-IB-AAUR-01A	67 years, male, white, stage:iib, alive, 338 days	4397.4
TCGA-FB-A78T-01A	71 years, female, white, stage:iib, dead, 375 days	4365.5
TCGA-XN-A8T3-01A	67 years, male, white, stage:ib, alive, 951 days	4331.3
TCGA-3A-A9IJ-01A	65 years, male, white, stage:ib, alive, 1854 days	4249.4
TCGA-FB-A4P5-01A	69 years, female, white, stage:iib, dead, 179 days	4226.3
TCGA-3A-A9IR-01A	64 years, female, white, stage:ib, alive, 1542 days	4225.8
TCGA-FB-A7DR-01A	48 years, male, asian, stage:iia, dead, 353 days	4179.5
TCGA-HZ-A49I-01A	77 years, male, white, stage:iib, dead, 308 days	4139.7
TCGA-IB-AAUW-01A	63 years, female, white, stage:iib, dead, 230 days	4106.6
TCGA-IB-AAUU-01A	35 years, male, white, stage:iib, alive, 245 days	4090.7
TCGA-F2-6880-01A	70 years, male, white, stage:iib, alive, 289 days	4077.8
TCGA-HZ-A77Q-01A	55 years, female, white, stage:iib, alive, 33 days	3927.6
TCGA-HV-A5A4-01A	72 years, female, asian, stage:iia, alive, 232 days	3896.1
TCGA-HV-A7OP-01A	72 years, male, asian, stage:iib, alive, 978 days	3845.3
TCGA-IB-AAUM-01A	76 years, male, white, stage:iib, alive, 8 days	3827.8
TCGA-IB-A7M4-01A	81 years, male, white, stage:iib, alive, 483 days	3808.8
TCGA-RL-AAAS-01A	60 years, female, white, stage:ib, alive, 9 days	3803.9
TCGA-S4-A8RO-01A	75 years, female, white, stage:iib, alive, 525 days	3774.8
TCGA-US-A77J-01A	81 years, female, white, stage:iib, dead, 568 days	3773.7
TCGA-IB-AAUT-01A	65 years, male, white, stage:iib, alive, 287 days	3773.2
TCGA-IB-AAUS-01A	84 years, female, white, stage:iib, alive, 225 days	3714.4
TCGA-IB-AAUN-01A	74 years, female, white, stage:ib, dead, 144 days	3694.8
TCGA-Z5-AAPL-01A	74 years, female, white, stage:iia, alive, 467 days	3643.3
TCGA-2J-AAB9-01A	71 years, female, white, stage:iib, dead, 627 days	3595.6
TCGA-FB-A4P6-01A	54 years, male, white, stage:iib, alive, 767 days	3574.8
TCGA-US-A774-01A	76 years, female, white, stage:iib, dead, 695 days	3565.3
TCGA-YB-A89D-01A	59 years, male, white, stage:iib, alive, 350 days	3562.4
TCGA-3A-A9IB-01A	69 years, female, white, stage:iib, dead, 224 days	3515.6
TCGA-HZ-8636-01A	58 years, female, white, stage:iv, dead, 545 days	3494.8
TCGA-IB-AAUP-01A	68 years, male, white, stage:iib, alive, 431 days	3480.1
TCGA-RB-AA9M-01A	43 years, male, white, stage:iib, alive, 286 days	3467.9
TCGA-HZ-7923-01A	65 years, male, white, stage:iia, alive, 314 days	3449.7
TCGA-IB-7885-01A	78 years, female, white, stage:iib, alive, 1257 days	3441.6
TCGA-YY-A8LH-01A	61 years, female, white, stage:iib, alive, 2016 days	3431.5
TCGA-HZ-A4BH-01A	75 years, male, white, stage:iib, alive, 194 days	3430.2
TCGA-FB-A545-01A	72 years, female, white, stage:iib, dead, 732 days	3408.7
TCGA-IB-7645-01A	44 years, female, stage:iib, dead, 1502 days	3396.5
TCGA-IB-A7LX-01A	57 years, male, white, stage:iib, dead, 250 days	3363.7
TCGA-IB-7887-01A	62 years, female, white, stage:iib, dead, 110 days	3354.9
TCGA-3A-A9IC-01A	61 years, female, white, stage:iib, dead, 738 days	3342.9
TCGA-HZ-7924-01A	60 years, female, white, stage:iia, alive, 840 days	3323.8
TCGA-IB-AAUV-01A	49 years, male, white, stage:iib, alive, 404 days	3274.8
TCGA-IB-7644-01A	65 years, female, white, stage:iv, dead, 394 days	3256.8
TCGA-IB-A5SQ-01A	56 years, female, white, stage:ib, dead, 219 days	3249.1
TCGA-IB-A5ST-01A	64 years, female, white, stage:iib, alive, 635 days	3220.6
TCGA-F2-A7TX-01A	77 years, male, white, stage:iib, dead, 95 days	3218.3
TCGA-IB-7652-01A	49 years, female, asian, stage:iib, alive, 1116 days	3136.1
TCGA-3E-AAAZ-01A	71 years, male, white, stage:iia, dead, 2182 days	3127.6
TCGA-IB-7889-01A	86 years, female, white, stage:iib, dead, 481 days	3126.1
TCGA-3A-A9IO-01A	56 years, male, white, alive, 1942 days	3116.6
TCGA-2J-AAB6-01A	75 years, male, white, stage:iia, dead, 293 days	3058.2
TCGA-IB-7651-01A	64 years, female, white, stage:iib, dead, 603 days	3035.8
TCGA-IB-8127-01A	59 years, male, white, stage:iib, alive, 522 days	2953.1
TCGA-HV-A7OL-01A	70 years, male, asian, stage:iia, alive, 252 days	2933.5
TCGA-FB-A5VM-01A	74 years, male, white, stage:ib, dead, 498 days	2926.2
TCGA-XD-AAUL-01A	56 years, male, white, stage:iia, alive, 498 days	2868.5
TCGA-3A-A9IU-01A	65 years, male, white, stage:iib, dead, 458 days	2864.4
TCGA-HZ-A77O-01A	77 years, female, white, stage:iib, dead, 160 days	2817.3
TCGA-IB-7646-01A	60 years, male, white, stage:iib, dead, 145 days	2788.9
TCGA-2L-AAQA-01A	76 years, male, white, stage:iib, dead, 143 days	2755.7
TCGA-IB-7897-01A	54 years, female, white, stage:iib, dead, 486 days	2748.6
TCGA-H6-8124-01A	56 years, female, white, stage:iib, alive, 392 days	2725.8
TCGA-HZ-8001-01A	69 years, male, white, stage:iii, alive, 706 days	2663.2
TCGA-F2-7276-01A	64 years, male, white, stage:iib, dead, 216 days	2652.0
TCGA-LB-A9Q5-01A	63 years, female, white, stage:iib, dead, 313 days	2623.6
TCGA-2J-AABV-01A	74 years, male, white, stage:iib, dead, 652 days	2611.3
TCGA-2J-AABP-01A	58 years, female, white, stage:iib, alive, 463 days	2540.3
TCGA-LB-A8F3-01A	64 years, female, black or african american, stage:iia, alive, 379 days	2490.7
TCGA-IB-7654-01A	80 years, male, white, stage:iib, dead, 476 days	2489.9
TCGA-3A-A9IZ-01A	47 years, male, white, stage:iib, dead, 308 days	2480.8
TCGA-HZ-8002-01A	61 years, male, white, stage:iib, dead, 366 days	2281.6
TCGA-HZ-7926-01A	57 years, male, black or african american, stage:iib, dead, 518 days	2278.1
TCGA-HZ-7925-01A	66 years, male, white, stage:iib, dead, 614 days	2266.3
TCGA-IB-7890-01A	73 years, male, stage:ib, dead, 598 days	1978.3
TCGA-IB-A5SS-01A	64 years, female, white, stage:iib, dead, 460 days	1890.9
TCGA-HZ-8003-01A	65 years, female, white, stage:iib, dead, 596 days	1887.8
TCGA-HZ-7920-01A	71 years, male, white, stage:ib, dead, 236 days	1881.2
TCGA-HZ-7919-01A	52 years, female, white, stage:iib, dead, 593 days	1845.6
TCGA-IB-7888-01A	66 years, female, black or african american, stage:iia, dead, 1332 days	1779.3
TCGA-F2-6879-01A	57 years, male, white, stage:iib, dead, 334 days	1769.5
TCGA-IB-7891-01A	49 years, female, white, stage:iib, dead, 913 days	1735.6
TCGA-HZ-7918-01A	72 years, male, white, stage:iib, alive, 969 days	1392.5
TCGA-IB-7893-01A	64 years, male, white, stage:iia, dead, 117 days	1279.9
TCGA-HZ-8005-01A	81 years, male, white, stage:iib, dead, 120 days	1209.3
TCGA-HZ-7922-01A	61 years, female, white, stage:iib, alive, 4 days	1193.8
TCGA-F2-7273-01A	54 years, male, black or african american, stage:iib, dead, 592 days	1075.0
TCGA-IB-7886-01A	80 years, male, white, stage:iib, dead, 123 days	984.8
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PANCREATIC CANCER - Protein expressionⁱ

Pending cancer tissue analysis