Expression of MT-ATP6 in colorectal cancer

RECTUM ADENOCARCINOMA (READ) - Interactive survival scatter plotⁱ

The Survival Scatter plot shows the clinical status (i.e. dead or alive) for all individuals in the patient cohort, based on the same data that underlies the corresponding Kaplan-Meier plots. Patients that are alive at last time for follow-up are shown in blue and patients who have died during the study are shown in red.

The x-axis shows the expression levels (FPKM) of the investigated gene in the tumor tissue at the time of diagnosis. The y-axis shows the follow-up time after diagnosis (years). Both axes are complimented with kernel density curves demonstrating the data density over the axes. The top density plot shows the expression levels (FPKM) distribution among dead (red) and alive patients (blue). The right density plot shows the data density of the survived years of dead patients with high and low expression levels respectively, stratified using the cutoff indicated by the vertical dashed line through the Survival Scatter plot. This cutoff is automatically defined based on the FPKM cutoff that minimizes the p-score. The cutoff can be changed by dragging the vertical line or by entering a cutoff value in the square labeled "Current cut-off".

Under the Survival Scatter plot the p-score landscape (black curve; left axis) is shown together with dead median separation (red curve; right axis). Dead median separation is the difference in median mRNA expression between patients who have died with high and low expression, respectively. It is calculated as follows: median FPKM expression of dead patients with high expression - median FPKM expression of dead patients with low expression. This is intended to aid the user in visually exploring custom cutoffs and the associated p-scores and dead median separation.

Individual patient data is displayed and can be filtered by clicking on one or more of the category buttons on the top of the page. Categories describing expression level and patient information include: high, low, alive, dead, female, male and tumor stages. The scale of the x-axis can be toggled between linear and log-scale by clicking on the "x log" button. Mouse-over function shows TCGA ID, patient information and mRNA expression (FPKM) for each patient.

& Survival analysisⁱ

Stage:

Survival analysis

Current cut offⁱ:
Best expression cut offⁱ: 4835.13
Median expressionⁱ: N/A
Median follow up timeⁱ: N/A
P scoreⁱ N/A
5-year survival highⁱ N/A
5-year survival lowⁱ N/A

TCGA RNA samplesⁱ

Average FPKM

6628.4

Number of samples

159

Samples

Sample	Description	FPKM
TCGA-DY-A1DF-01A	73 years, female, white, stage:iiic, dead, 734 days	37234.5
TCGA-F5-6812-01A	67 years, male, white, stage:iia, alive, 1110 days	19072.0
TCGA-DY-A1DD-01A	77 years, female, white, stage:iiib, dead, 1741 days	18958.2
TCGA-DY-A1H8-01A	77 years, female, white, stage:iiia, dead, 992 days	18751.3
TCGA-BM-6198-01A	73 years, male, white, stage:iiib, alive, 646 days	17613.2
TCGA-AG-A026-01A	66 years, male, stage:ii, dead, 59 days	15220.2
TCGA-DY-A1DG-01A	75 years, male, white, stage:iva, dead, 1566 days	14481.3
TCGA-CL-5918-01A	90 years, female, white, stage:iia, alive, 218 days	13590.0
TCGA-AG-A011-01A	80 years, male, stage:iia, alive, 1126 days	13323.1
TCGA-AG-A01J-01A	59 years, female, stage:iia, alive, 31 days	13254.2
TCGA-AG-A032-01A	68 years, male, stage:iiib, alive, 1157 days	13164.7
TCGA-DY-A1DC-01A	72 years, female, white, stage:iia, dead, 1258 days	13104.1
TCGA-AG-3882-01A	66 years, female, stage:i, alive, 608 days	11562.4
TCGA-AG-3593-01A	72 years, female, stage:iia, alive, 1035 days	11269.4
TCGA-EI-6514-01A	59 years, female, white, stage:iia, alive, 496 days	11032.4
TCGA-EI-6509-01A	53 years, male, white, stage:iiic, alive, 517 days	10842.5
TCGA-F5-6571-01A	62 years, female, white, stage:iia, alive, 1288 days	10798.5
TCGA-G5-6235-01A	72 years, male, white, stage:iiib, alive, 1696 days	10679.6
TCGA-AG-A02N-01A	67 years, male, stage:ii, alive, 1885 days	10656.4
TCGA-AG-3592-01A	68 years, male, stage:iia, alive, 1035 days	10481.1
TCGA-AG-A015-01A	64 years, female, stage:i, alive, 1096 days	10279.9
TCGA-AH-6544-01A	60 years, male, white, alive, 1173 days	10105.4
TCGA-AG-A025-01A	62 years, female, stage:i, alive, 1520 days	9975.1
TCGA-AG-A002-01A	35 years, male, stage:i, alive, 638 days	9966.5
TCGA-CI-6624-01C	53 years, female, white, stage:i, alive, 1466 days	9665.9
TCGA-AG-3893-01A	74 years, male, stage:iiib, alive, 1065 days	9305.7
TCGA-EI-6510-01A	77 years, female, white, alive, 556 days	9141.7
TCGA-AF-2691-01A	48 years, female, white, stage:i, alive, 1309 days	9120.0
TCGA-AG-3732-01A	78 years, female, stage:i, alive, 1003 days	8997.0
TCGA-AG-A014-01A	86 years, male, stage:i, alive, 485 days	8925.6
TCGA-AG-3890-01A	62 years, male, stage:i, alive, 518 days	8898.1
TCGA-AH-6643-01A	50 years, male, white, stage:iiic, dead, 1314 days	8648.8
TCGA-AG-3898-01A	61 years, male, stage:iia, alive, 1461 days	8619.1
TCGA-CL-4957-01A	79 years, female, dead, 425 days	8570.1
TCGA-G5-6233-01A	74 years, male, white, dead, 556 days	8490.1
TCGA-G5-6641-01A	67 years, male, white, stage:iiia, alive, 804 days	8431.6
TCGA-EF-5831-01A	72 years, male, white, stage:iia, alive, 127 days	8413.0
TCGA-AF-2692-01A	54 years, female, white, stage:iia, alive, 412 days	8307.6
TCGA-AG-A036-01A	71 years, male, stage:iii, alive, 3562 days	8282.2
TCGA-DY-A0XA-01A	57 years, female, white, stage:iia, alive, 3846 days	8144.6
TCGA-EI-6513-01A	59 years, male, white, stage:iiib, alive, 497 days	8073.3
TCGA-AG-A01N-01A	68 years, female, stage:iv, alive, 943 days	7832.5
TCGA-AG-A023-01A	62 years, female, stage:iv, dead, 1581 days	7738.4
TCGA-AF-5654-01A	73 years, female, white, stage:i, dead, 512 days	7706.5
TCGA-AG-A00C-01A	49 years, female, stage:iiib, alive, 183 days	7704.2
TCGA-F5-6813-01A	70 years, male, white, stage:iiic, dead, 598 days	7672.2
TCGA-CI-6619-01B	41 years, male, white, stage:iv, alive, 184 days	7612.0
TCGA-AF-6672-01A	43 years, male, white, stage:iv, alive, 748 days	7597.1
TCGA-DT-5265-01A	51 years, male, asian, stage:ii, alive, 384 days	7576.0
TCGA-AG-3878-01A	64 years, male, stage:i, alive, 30 days	7506.0
TCGA-DC-6682-01A	57 years, male, white, stage:iia, alive, 762 days	7445.3
TCGA-AG-3742-01A	85 years, female, stage:i, alive, 30 days	7434.4
TCGA-AG-3583-01A	66 years, male, stage:iv, dead, 610 days	7380.8
TCGA-AH-6547-01A	79 years, female, white, dead, 76 days	7361.5
TCGA-AG-3725-01A	90 years, female, stage:iii, alive, 638 days	7241.0
TCGA-G5-6572-01A	56 years, male, white, dead, 1432 days	7073.8
TCGA-AG-3578-01A	76 years, female, stage:iia, alive, 974 days	7012.9
TCGA-AG-A00H-01A	75 years, male, stage:iia, alive, 790 days	6954.0
TCGA-EI-6506-01A	78 years, female, white, stage:iia, alive, 625 days	6915.0
TCGA-CI-6622-01A	74 years, male, white, stage:iib, alive, 1362 days	6812.9
TCGA-AG-A020-01A	57 years, female, stage:iii, alive, 31 days	6713.5
TCGA-AG-4022-01A	59 years, female, stage:ii, alive, 1400 days	6702.8
TCGA-CI-6623-01B	44 years, male, white, stage:i, alive, 1443 days	6588.4
TCGA-AG-3584-01A	60 years, male, stage:iv, dead, 730 days	6567.8
TCGA-AG-3580-01A	67 years, male, stage:i, alive, 244 days	6497.2
TCGA-AH-6903-01A	46 years, male, white, stage:iiib, alive, 592 days	6490.7
TCGA-EF-5830-01A	54 years, male, white, stage:iib, alive, 106 days	6461.2
TCGA-AF-A56K-01A	56 years, male, black or african american, stage:iia, alive, 2635 days	6416.5
TCGA-AG-4008-01A	63 years, male, stage:iia, alive, 518 days	6384.6
TCGA-AG-3612-01A	55 years, female, stage:iiib, alive, 608 days	6349.8
TCGA-F5-6702-01A	71 years, male, white, stage:iva, alive, 869 days	6344.8
TCGA-AF-3911-01A	48 years, male, white, stage:iiic, alive, 1148 days	6310.0
TCGA-CI-6621-01A	63 years, male, white, stage:iiib, alive, 419 days	6238.3
TCGA-DY-A1DE-01A	56 years, female, white, stage:iia, alive, 3932 days	6189.8
TCGA-EI-6881-01A	60 years, male, white, stage:iiia, alive, 499 days	6123.5
TCGA-F5-6811-01A	72 years, female, white, stage:iia, alive, 979 days	6111.1
TCGA-AG-A02G-01A	66 years, male, stage:iv, dead, 1185 days	6075.1
TCGA-AF-2687-01A	57 years, male, white, stage:iiic, alive, 1427 days	6053.0
TCGA-CI-6620-01A	41 years, female, white, stage:iva, alive, 1009 days	6021.2
TCGA-AG-A00Y-01A	68 years, male, stage:iia, alive, 700 days	5995.5
TCGA-AG-4001-01A	74 years, female, stage:iia, alive, 1096 days	5901.1
TCGA-AG-3883-01A	69 years, male, stage:i, alive, 31 days	5880.2
TCGA-AG-3600-01A	62 years, male, stage:iiic, alive, 184 days	5805.6
TCGA-AG-3574-01A	89 years, female, stage:ii, dead, 1096 days	5768.5
TCGA-AG-3586-01A	72 years, female, stage:iii, alive, 31 days	5754.0
TCGA-AG-3909-01A	69 years, female, stage:iiib, alive, 608 days	5664.9
TCGA-AG-A016-01A	55 years, male, stage:iv, alive, 276 days	5620.0
TCGA-AG-A02X-01A	77 years, male, stage:i, alive, 1247 days	5613.6
TCGA-EI-6512-01A	64 years, female, white, stage:iiib, alive, 538 days	5580.2
TCGA-AG-3999-01A	61 years, female, stage:iiic, alive, 853 days	5481.9
TCGA-EI-6511-01A	52 years, male, white, stage:iiib, alive, 482 days	5393.8
TCGA-F5-6465-01A	64 years, female, white, stage:iia, alive, 1506 days	5382.8
TCGA-AG-4021-01A	84 years, female, stage:iv, dead, 121 days	5203.7
TCGA-DC-6683-01A	43 years, male, white, stage:iiib, alive, 762 days	5185.1
TCGA-AG-3591-01A	66 years, female, stage:iia, alive, 1035 days	5174.9
TCGA-AG-3594-01A	77 years, male, stage:iia, dead, 61 days	5131.5
TCGA-AF-6136-01A	72 years, female, white, stage:iiib, alive, 741 days	5087.0
TCGA-AF-4110-01A	77 years, male, white, stage:iva, alive, 912 days	5074.6
TCGA-AG-A008-01A	50 years, female, stage:i, alive, 424 days	5055.6
TCGA-AG-3582-01A	75 years, male, stage:iv, dead, 1096 days	4977.0
TCGA-AH-6644-01A	73 years, male, white, alive, 838 days	4924.0
TCGA-AF-2690-01A	77 years, female, white, stage:iiic, dead, 524 days	4878.9
TCGA-AG-4005-01A	64 years, male, stage:iv, alive, 427 days	4867.4
TCGA-F5-6464-01A	77 years, female, white, stage:iiic, dead, 303 days	4865.2
TCGA-AH-6549-01A	66 years, male, white, alive, 532 days	4805.0
TCGA-AG-3726-01A	63 years, female, stage:i, alive, 243 days	4766.9
TCGA-EI-6508-01A	48 years, female, white, stage:iiib, alive, 636 days	4706.3
TCGA-AG-3731-01A	65 years, male, stage:iv, alive, 1126 days	4685.5
TCGA-AF-6655-01A	66 years, male, white, stage:iiia, alive, 609 days	4629.5
TCGA-AF-2693-01A	75 years, male, white, stage:i, alive, 1155 days	4619.4
TCGA-AG-3581-01A	63 years, male, stage:i, alive, 215 days	4583.3
TCGA-AG-3611-01A	72 years, male, stage:iia, alive, 424 days	4395.0
TCGA-AG-3901-01A	67 years, female, stage:iiib, alive, 761 days	4383.6
TCGA-AG-3608-01A	79 years, female, stage:iia, alive, 485 days	4337.7
TCGA-CL-5917-01A	71 years, female, white, stage:iiic, alive, 2376 days	4213.0
TCGA-DC-6157-01A	48 years, male, black or african american, stage:i, alive, 1581 days	4209.3
TCGA-AG-4007-01A	87 years, male, stage:iv, alive, 31 days	4209.0
TCGA-F5-6861-01A	60 years, female, white, stage:iia, alive, 1160 days	4155.0
TCGA-AF-A56L-01A	48 years, female, black or african american, stage:iiic, alive, 2007 days	3985.3
TCGA-AG-3587-01A	65 years, male, stage:i, alive, 1400 days	3971.5
TCGA-F5-6864-01A	74 years, female, white, stage:iiib, alive, 379 days	3969.5
TCGA-DC-6160-01A	68 years, male, white, stage:i, alive, 1339 days	3958.7
TCGA-F5-6814-01A	57 years, male, white, stage:iia, alive, 1131 days	3940.8
TCGA-AG-3896-01A	85 years, female, stage:i, alive, 31 days	3915.8
TCGA-AF-3400-01A	54 years, male, white, stage:iia, alive, 1049 days	3901.8
TCGA-DC-4749-01A	57 years, male, white, stage:i, alive, 762 days	3757.4
TCGA-AG-3902-01A	61 years, male, stage:iia, alive, 974 days	3740.0
TCGA-AG-3885-01A	71 years, female, stage:iiib, alive, 546 days	3723.3
TCGA-DC-6156-01A	62 years, male, white, stage:iva, alive, 943 days	3695.7
TCGA-AG-3887-01A	68 years, male, stage:iia, alive, 1124 days	3647.8
TCGA-AF-A56N-01A	47 years, female, black or african american, stage:iia, alive, 360 days	3550.1
TCGA-DC-6681-01A	70 years, female, white, stage:iva, alive, 790 days	3535.9
TCGA-AG-3605-01A	85 years, female, stage:iv, alive, 30 days	3431.4
TCGA-AG-3894-01A	65 years, male, stage:iia, alive, 426 days	3426.3
TCGA-AG-3892-01A	57 years, female, stage:i, alive, 396 days	3218.4
TCGA-AG-3881-01A	83 years, female, stage:iia, alive, 579 days	3117.2
TCGA-EI-6883-01A	63 years, male, white, stage:iic, alive, 350 days	2987.0
TCGA-AG-3599-01A	70 years, male, stage:i, alive, 366 days	2967.4
TCGA-AG-3727-01A	78 years, female, stage:iii, alive, 30 days	2964.5
TCGA-DC-6158-01A	70 years, male, white, stage:i, dead, 334 days	2946.4
TCGA-F5-6863-01A	71 years, female, white, stage:iiib, dead, 361 days	2646.1
TCGA-AG-3728-01A	73 years, male, stage:iiib, alive, 912 days	2585.0
TCGA-AG-3598-01A	69 years, male, stage:iia, alive, 1522 days	2505.0
TCGA-EI-6507-01A	60 years, male, white, stage:iia, alive, 607 days	2461.6
TCGA-AF-3913-01A	60 years, male, black or african american, stage:iv, dead, 316 days	2267.4
TCGA-AG-3609-01A	65 years, female, stage:iiic, alive, 608 days	2210.6
TCGA-EI-6885-01A	57 years, female, white, stage:iv, alive, 415 days	2001.6
TCGA-EI-6882-01A	59 years, male, white, stage:iia, alive, 262 days	1915.8
TCGA-EI-7002-01A	58 years, male, white, stage:iv, alive, 364 days	1773.2
TCGA-DC-4745-01A	49 years, female, white, stage:iiib, alive, 639 days	1764.9
TCGA-EI-6917-01A	33 years, male, white, stage:iiia, alive, 531 days	1732.1
TCGA-AH-6897-01A	48 years, male, white, stage:i, alive, 804 days	1699.3
TCGA-DC-6155-01A	31 years, female, white, stage:iiia, alive, 425 days	1580.9
TCGA-EI-6884-01A	71 years, male, white, stage:iiia, alive, 328 days	1517.9
TCGA-DC-6154-01A	57 years, female, white, stage:iva, alive, 365 days	1465.1
TCGA-DC-5337-01A	69 years, male, white, stage:i, alive, 792 days	1116.0
TCGA-AG-3575-01A	51 years, male, stage:ii, alive, 365 days	1057.1
TCGA-EI-7004-01A	37 years, female, white, alive, 257 days	956.2
TCGA-DC-5869-01A	62 years, female, black or african american, stage:iiib, alive, 943 days	686.5
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